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List of works by Seppo Ylä-Herttuala

(Strept)avidin-displaying lentiviruses as versatile tools for targeting and dual imaging of gene delivery

scientific article

10-year safety follow-up in patients with local VEGF gene transfer to ischemic lower limb

scientific article published on 21 July 2011

14q32 miRNA Cluster Takes Center Stage in Neovascularization

scientific article published on 01 September 2014

15-Lipoxygenase-1 induces lipid peroxidation and apoptosis, and improves survival in rat malignant glioma

scientific article published on January 1, 2012

15-lipoxygenase-1 prevents vascular endothelial growth factor A- and placental growth factor-induced angiogenic effects in rabbit skeletal muscles via reduction in growth factor mRNA levels, NO bioactivity, and downregulation of VEGF receptor 2 expr

scientific article published on 8 November 2007

18-kDa translocator protein ligand 18F-FEMPA: Biodistribution and uptake into atherosclerotic plaques in mice

scientific article published on 25 May 2016

1H MR spectroscopic imaging of phospholipase-mediated membrane lipid release in apoptotic rat glioma in vivo

scientific article

1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis.

scientific article published in November 1999

6-o- and N-sulfated syndecan-1 promotes baculovirus binding and entry into Mammalian cells

scientific article published on 07 August 2013

68Ga-DOTA-RGD peptide: biodistribution and binding into atherosclerotic plaques in mice

scientific article

A 96-well format for a high-throughput baculovirus generation, fast titering and recombinant protein production in insect and mammalian cells

scientific article

A New Gene Therapy Approach for Cardiovascular Disease by Non-coding RNAs Acting in the Nucleus

scientific article

A highly reproducible xenograft model for human ovarian carcinoma and application of MRI and ultrasound in longitudinal follow-up

scientific article published on 4 May 2006

A model for gene therapy of human hereditary lymphedema

scientific article (publication date: 23 October 2001)

A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo

scientific article

A preclinical assessment of the safety and biodistribution of an adenoviral vector containing the herpes simplex virus thymidine kinase gene (Cerepro) after intracerebral administration

scientific article published in June 2009

A stable bis-allyloxycarbonyl biotin aldehyde derivative for biotinylation via reductive alkylation: application to the synthesis of a biotinylated doxorubicin derivative

scientific article published in January 2003

AAV9-mediated VEGF-B gene transfer improves systolic function in progressive left ventricular hypertrophy

scientific article

ADA-SCID Gene Therapy Endorsed By European Medicines Agency For Marketing Authorization

scientific article published on June 2016

ADVANCES AND CHALLENGES IN CARDIOVASCULAR GENE THERAPY.

scientific article published on 16 August 2017

ASGCT Annual Meeting 2019

scientific article published on 18 July 2019

Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle

scientific article published on 14 May 2009

Activating the Chromatin by Noncoding RNAs

scientific article

Activation of Peroxisome Proliferator-Activated Receptor-δ as Novel Therapeutic Strategy to Prevent In-Stent Restenosis and Stent Thrombosis

scientific article published on 9 June 2016

Acute infections in children are accompanied by oxidative modification of LDL and decrease of HDL cholesterol, and are followed by thickening of carotid intima-media

scientific article published in March 2003

Acute respiratory viral infections aggravate arterial endothelial dysfunction in children with type 1 diabetes

scientific article published in November 2004

AdVEGF-B186 and AdVEGF-DΔNΔC induce angiogenesis and increase perfusion in porcine myocardium

scientific article published on 12 May 2016

Adeno-associated virus-mediated gene transfer of a secreted decoy human macrophage scavenger receptor reduces atherosclerotic lesion formation in LDL receptor knockout mice

scientific article published in December 2003

Adenoviral VEGF-A gene transfer induces angiogenesis and promotes bone formation in healing osseous tissues

scientific article published in July 2003

Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes

scientific article published on July 2002

Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart

scientific article published on 16 February 2004

Adenoviral expression of 15-lipoxygenase-1 in rabbit aortic endothelium: role in arachidonic acid-induced relaxation

article

Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up

scientific article published in September 2017

Adenovirus mediated herpes simplex virus-thymidine kinase/ganciclovir gene therapy for resectable malignant glioma

scientific article published on October 2009

Adenovirus-Mediated Gene Transfer of Placental Growth Factor to Perivascular Tissue Induces Angiogenesis via Upregulation of the Expression of Endogenous Vascular Endothelial Growth Factor-A

article

Adenovirus-Mediated Gene Transfer to Lower Limb Artery of Patients with Chronic Critical Leg Ischemia ⬇️

scientific article published on July 1, 1998

Adenovirus-mediated extracellular superoxide dismutase gene therapy reduces neointima formation in balloon-denuded rabbit aorta

scientific article published in October 2002

Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial

scientific article published on 12 July 2013

Adenovirus-mediated gene transfer into an experimental pancreatic tumour.

scientific article published in January 2000

Adenovirus-mediated gene transfer of Lp-PLA2 reduces LDL degradation and foam cell formation in vitro

scientific article published in July 2004

Adenovirus-mediated gene transfer of a secreted decoy human macrophage scavenger receptor (SR-AI) in LDL receptor knock-out mice

Adenovirus-mediated gene transfer of a secreted form of human macrophage scavenger receptor inhibits modified low-density lipoprotein degradation and foam-cell formation in macrophages

scientific article published in March 2000

Adenovirus-mediated gene transfer of human vascular endothelial growth factor-d induces transient angiogenic effects in mouse hind limb muscle

article

Adenovirus-mediated herpes simplex virus thymidine kinase gene therapy in BT4C rat glioma model

scientific article published in November 2002

Adenovirus‐mediated VEGF‐A gene transfer induces bone formationin vivo ⬇️

scientific article published on April 8, 2003

AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study

scientific article published in November 2004

Adventitial VEGF165 gene transfer prevents lumen loss through induction of positive arterial remodeling after PTCA in porcine coronary arteries

scientific article published on 24 January 2006

Adventitial gene transfer of VEGFR-2 specific VEGF-E chimera induces MCP-1 expression in vascular smooth muscle cells and enhances neointimal formation.

scientific article

Adventitial gene transfer to arterial wall

scientific article

All Eyes and Ears for Gene Therapy ⬇️

scientific article published on 11 July 2018

Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation by positron emission tomography.

scientific article

Amyloid-Targeting PET Tracer [F]Flutemetamol Accumulates in Atherosclerotic Plaques

scientific article published on 19 March 2019

An Efficient Faint Object Spectrograph

scientific article published on 01 August 1998

An update on angiogenic gene therapy: vascular endothelial growth factor and other directions.

scientific article published on August 2006

Analysis of fat graft metabolic adaptation and vascularization using positron emission tomography-computed tomographic imaging

scientific article

Analysis of gene and protein expression during monocyte-macrophage differentiation and cholesterol loading—cDNA and protein array study

article

Angiogenesis, Vascular Endothelial Growth Factor and Platelet-Derived Growth Factor-BB Expression, Iron Deposition, and Oxidation-Specific Epitopes in Stented Human Coronary Arteries ⬇️

scientific article published on November 1, 2001

Angiogenesis-Dependent and Independent Phases of Intimal Hyperplasia

scientific article published on 11 October 2004

Angiogenic Responses of Vascular Endothelial Growth Factors in Periadventitial Tissue

article

Angiogenic gene therapy in cardiovascular diseases: dream or vision?

scientific article published on 10 January 2017

Angiographically guided utero-placental gene transfer in rabbits with adenoviruses, plasmid/liposomes and plasmid/polyethyleneimine complexes

scientific article

Angiopoietin-1 Protects Against the Development of Cardiac Allograft Arteriosclerosis

article

Angiopoietin-1 promotes lymphatic sprouting and hyperplasia.

scientific article published on 3 March 2005

Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice

scientific article

Angiopoietin-regulated recruitment of vascular smooth muscle cells by endothelial-derived heparin binding EGF-like growth factor

scientific article published in September 2003

Animal Models of Gene Therapy for Cardiovascular Disease

article

Animal models of diabetic macrovascular complications: key players in the development of new therapeutic approaches

scientific article

Antegrade flow and peripheral resistance determine the level of endogenous arteriogenesis in patients with superficial femoral artery occlusion

scientific article published on 06 October 2009

Antiangiogenic gene therapy with soluble VEGF-receptors -1, -2 and -3 together with paclitaxel prolongs survival of mice with human ovarian carcinoma

scientific article

Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice

scientific article

Antibodies against oxidized LDL and cardiolipin and mortality in patients with coronary heart disease

scientific article

Antibody reactivity to an Epstein-Barr virus BERF4-encoded epitope occurring also in Asp-57 region of HLA-DQ8 beta chain. Childhood Diabetes in Finland Study Group.

scientific article

Antioxidant gene therapy for cardiovascular disease: current status and future perspectives

scientific article published on April 2008

Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

scientific article published in May 1990

Apolipoprotein A-I mimetic peptide 4F blocks sphingomyelinase-induced LDL aggregation

scientific article published on 10 April 2015

Apolipoprotein E and colon cancer

scientific article published on 01 February 2002

Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

scientific article

Artifact occurring during combined in situ hybridization and immunocytochemistry analysis because of positive chemography

scientific article published on 01 May 1998

Assessment of myocardial viability with [15O]water PET: A validation study in experimental myocardial infarction

scientific article published on 17 July 2019

Assignment of 1H nuclear magnetic resonance visible polyunsaturated fatty acids in BT4C gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death

scientific article

Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects

scientific article published in February 2003

Atherosclerosis and biochemical composition of coronary arteries in Finnish men Comparison of two populations with different incidences of coronary heart disease

article

Autoantibodies against oxidized LDL and endothelium-dependent vasodilation in insulin-dependent diabetes mellitus

scientific article published on 01 November 1999

Autoantibodies against oxidized LDL are associated with severe chest pain attacks in patients with coronary heart disease

scientific article

Autoantibodies against oxidized LDL do not predict atherosclerotic vascular disease in non-insulin-dependent diabetes mellitus

scientific article published in October 1996

Autoantibodies against oxidized low density lipoprotein in patients with angiographically verified coronary artery disease

scientific article published in January 1999

Autoantibody against oxidised LDL and progression of carotid atherosclerosis

scientific article published in The Lancet

Avidin Fusion Protein Strategies in Targeted Drug and Gene Delivery

article

Avidin fusion protein-expressing lentiviral vector for targeted drug delivery.

scientific article published in August 2009

Avidin-biotin technology in targeted therapy

scientific article published on May 2010

Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function

scientific article published on 12 March 2019

BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF

scientific article published on 06 October 2020

Baculovirus capsid display: a novel tool for transduction imaging

scientific article published on November 2003

Baculovirus is an efficient vector for the transduction of the eye: comparison of baculovirus- and adenovirus-mediated intravitreal vascular endothelial growth factor D gene transfer in the rabbit eye.

scientific article published in May 2009

Baculovirus-mediated gene delivery and RNAi applications

scientific article published on 22 April 2015

Baculovirus-mediated immediate-early gene expression and nuclear reorganization in human cells

scientific article published on 27 November 2007

Baculovirus-mediated periadventitial gene transfer to rabbit carotid artery

scientific article published in September 2000

Baculovirus-mediated vascular endothelial growth factor-D(ΔNΔC) gene transfer induces angiogenesis in rabbit skeletal muscle

scientific article

Baculovirus: an insect-derived vector for diverse gene transfer applications

scientific article published on 26 February 2013

Baculoviruses exhibit restricted cell type specificity in rat brain: a comparison of baculovirus- and adenovirus-mediated intracerebral gene transfer in vivo

scientific article published in December 2002

Baculoviruses mediate efficient gene expression in a wide range of vertebrate cells

scientific article published on January 2011

Baseline diene conjugation in LDL lipids as a direct measure of in vivo LDL oxidation

scientific article published in June 1998

Beta-galactosidase gene transfer to human malignant glioma in vivo using replication-deficient retroviruses and adenoviruses

scientific article published in August 1998

Beyond endothelial cells: Vascular endothelial growth factors in heart, vascular anomalies and placenta

scientific article published on 17 October 2018

Bile-duct proliferation as an unexpected side-effect after AAV2-LDLR gene transfer to rabbit liver

article

Biochemical composition of human internal mammary artery and saphenous vein

article

Biodegradable coronary scaffolds: their future and clinical and technological challenges

scientific article published on 01 July 2018

Biodistribution and antitumor effect of Cetuximab-targeted lentivirus

scientific article published on 18 October 2013

Biodistribution of adenoviral vector to nontarget tissues after local in vivo gene transfer to arterial wall using intravascular and periadventitial gene delivery methods

scientific article published in November 2000

Biology of vascular endothelial growth factors

scientific article

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

scientific article

Blood flow remodels growing vasculature during vascular endothelial growth factor gene therapy and determines between capillary arterialization and sprouting angiogenesis

scientific article published on 12 December 2005

Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth

scientific article

Brain pharmacokinetics of ganciclovir in rats with orthotopic BT4C glioma

scientific article

Bumps in the Road for Commercial Gene Therapy for Rare Diseases

scientific article published on 19 September 2017

CRISPR/Cas9 and p53: An Odd Couple Requiring Relationship Management

scientific article published on 16 November 2018

Call for papers: Nanoparticle Development and Applications in Cellular and Molecular Therapies

scientific article published on August 2016

Cancer gene therapy — current status in the clinics

Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy

scientific article published on 7 December 2010

Cardiac Lymphatics - A New Avenue for Therapeutics?

scientific article published on 10 January 2017

CardioPulse: Progress in gene therapy for cardiovascular disease

scientific article published in April 2016

Cardiovascular Gene Therapy: Past, Present, and Future

scientific article published on 04 April 2017

Cardiovascular gene therapy with vascular endothelial growth factors

scientific article published on 20 April 2013

Catheter-mediated vascular endothelial growth factor gene transfer to human coronary arteries after angioplasty

scientific article published in January 2000

Cell susceptibility to baculovirus transduction and echovirus infection is modified by protein kinase C phosphorylation and vimentin organization

scientific article published on 3 July 2013

Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells

scientific article

Cerivastatin and hypercholesterolemia reduce apoptosis of cardiomyocytes in guinea pig papillary muscle subjected to hypoxia/reoxygenation

scientific article published on 01 May 2006

Challenges in monoclonal antibody-based therapies

scientific article published on January 2009

Changes in gene expression in atherosclerotic plaques analyzed using DNA array

article

Changes in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress

scientific article published on 17 July 2019

Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis

scientific article published on 01 August 2021

Characterization of atherosclerotic lesions in apo E3-leiden transgenic mice

scientific article published on 01 January 1998

Characterizing atherosclerotic lesions by in-plane ultrasonic TOF measurements

Clathrin-independent entry of baculovirus triggers uptake of E. coli in non-phagocytic human cells

scientific article (publication date: 2009)

Clinical applications of vascular gene therapy

scientific article

Clinical significance of apoptotic index in non-small cell lung cancer: correlation with p53, mdm2, pRb and p21WAF1/CIP1 protein expression

scientific article published on 01 September 2005

Clinical trials for glioblastoma multiforme using adenoviral vectors.

scientific article published on October 2009

Clonal variation in interferon response determines the outcome of oncolytic virotherapy in mouse CT26 colon carcinoma model.

scientific article published on 18 September 2014

Cloning and characterization of Scavidin, a fusion protein for the targeted delivery of biotinylated molecules

scientific article published on 12 December 2001

Cloning and characterization of soluble decoy receptors

scientific article

Clostridium difficile toxins induce VEGF-A and vascular permeability to promote disease pathogenesis

scientific article published on 03 December 2018

Co-infection with Chlamydia pneumoniae and Helicobacter pylori results in vascular endothelial dysfunction and enhanced VCAM-1 expression in apoE-knockout mice

scientific article published on March 2003

Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions ⬇️

scientific article published on September 1, 1990

Combined Gene Therapy Using AdsVEGFR2 and AdsTie2 With Chemotherapy Reduces the Growth of Human Ovarian Cancer and Formation of Ascites in Mice

scientific article published on 12 May 2017

Combined vascular endothelial growth factor-A and fibroblast growth factor 4 gene transfer improves wound healing in diabetic mice

scientific article published on 30 August 2010

Comparative Study Of Adeno-Associated Virus, Adenovirus, Baculovirus And Lentivirus Vectors For Gene Therapy Of The Eyes

scientific article published on 3 October 2017

Comparison of different ways of presenting the results of biochemical analyses of human coronary arteries

scientific article published on 01 July 1986

Comparison of the effects of alpha-tocopherol, ubiquinone-10 and probucol at therapeutic doses on atherosclerosis in WHHL rabbits

scientific article published in August 2002

Complement and anti-alpha-galactosyl natural antibody-mediated inactivation of murine retrovirus occurs in adult serum but not in umbilical cord serum

scientific article published on January 1999

Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C).

scientific article published on 26 December 2013

Conditional expression of Lodavin, an avidin-tagged LDL receptor, for biotin-mediated applications in vivo

scientific article published on 24 April 2012

Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China

article

Consensus guidelines for the use and interpretation of angiogenesis assays

article

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

scientific article

Corrigendum to “Non-invasive Imaging in Gene Therapy”

article

Corrigendum to “Primary effect of 1α,25(OH)2D3 on IL-10 expression in monocytes is short-term down-regulation” [Biochim. Biophys. Acta 1803 (2010) 1276–86]

scholarly article by Juha M. Matilainen published in December 2011

Cotargeting of VEGFR-1 and -3 and angiopoietin receptor Tie2 reduces the growth of solid human ovarian cancer in mice

scientific article published on 24 September 2010

Critical role of VEGF-C/VEGFR-3 signaling in innate and adaptive immune responses in experimental obliterative bronchiolitis.

scientific article

Culture medium induced vimentin reorganization associates with enhanced baculovirus-mediated gene delivery

Current gene therapy trials for vascular diseases

scientific article published on 03 January 2014

Current status of cardiovascular gene therapy

scientific article published on 8 May 2007

Cytochrome P450 2A5 constitutive expression and induction by heavy metals is dependent on redox-sensitive transcription factor Nrf2 in liver

scientific article published in May 2010

DNA hypomethylation and methyltransferase expression in atherosclerotic lesions

scientific article published in February 2002

DNA methylation processes in atheosclerotic plaque

scientific article published on 18 December 2018

DNA methylation, smooth muscle cells, and atherogenesis

scientific article

Debate on Germline Gene Editing

scientific article published in August 2016

Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis

scientific article published on 22 August 2004

Deletion of Lymphangiogenic and Angiogenic Growth Factor VEGF-D Leads to Severe Hyperlipidemia and Delayed Clearance of Chylomicron Remnants

scientific article published on 01 October 2018

Detection of Hypoxia by [ 18 F]EF5 in Atherosclerotic Plaques in Mice

Development of Lentiviral Vectors for Targeted Integration and Protein Delivery

scientific article published on January 2016

Development of Safe and Efficient Viral Vectors for Clinical Gene Therapy

Diet intervention reduces uptake of αvβ3 integrin-targeted PET tracer 18F-galacto-RGD in mouse atherosclerotic plaques

article by Antti Saraste et al published 20 April 2012 in Journal of Nuclear Cardiology

Dietary (n-3) fatty acids reduce plasma F2-isoprostanes but not prostaglandin F2alpha in healthy humans

scientific article published on 01 May 2006

Differences in retinal neovascular tissue and vitreous humour in patients with type 1 and type 2 diabetes

scientific article published on 19 March 2009

Different apolipoprotein B breakdown patterns in models of oxidized low density lipoprotein

scientific article published on 01 January 1999

Differential Promoter Methylation of Macrophage Genes Is Associated With Impaired Vascular Growth in Ischemic Muscles of Hyperlipidemic and Type 2 Diabetic Mice: Genome-Wide Promoter Methylation Study

scientific article published on 17 June 2015

Differential Regulation of Vascular Endothelial Growth Factors by Promoter-targeted shRNAs

scientific article published on 19 May 2015

Differential but Complementary HIF1α and HIF2α Transcriptional Regulation

scientific article published on 09 May 2018

Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8.

scientific article

Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins

scientific article published on 3 May 2007

Distinct metabolic and vascular effects of dietary triglycerides and cholesterol in atherosclerotic and diabetic mouse models

scientific article

Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting.

scientific article

Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits

scientific article published in May 1990

Does Nrf2 gene transfer facilitate recovery after contusion spinal cord injury?

scientific article published on 20 August 2013

Does mass balance between sense and antisense transcripts fine-tune the outcome of gene expression?

scientific article published on 15 January 2014

Dotted collar placed around carotid artery induces asymmetric neointimal lesion formation in rabbits without intravascular manipulations

scientific article

Down's syndrome and atherosclerosis

scientific article

Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction

scientific article published in Scientific Reports

Doxycycline modulates VEGF-A expression: Failure of doxycycline-inducible lentivirus shRNA vector to knockdown VEGF-A expression in transgenic mice

scientific article published on 19 January 2018

Doxycycline-regulated lentiviral vector system with a novel reverse transactivator rtTA2S-M2 shows a tight control of gene expression in vitro and in vivo

scientific article published in March 2003

Dual role of vascular endothelial growth factor in experimental obliterative bronchiolitis.

scientific article published on 18 March 2005

EC-SOD gene therapy reduces paracetamol-induced liver damage in mice

scientific article

ESGCT 2017 in Berlin: Clear Steps Forward

scientific article published on 28 November 2017

Early gene therapy-induced apoptotic response in BT4C gliomas by magnetic resonance relaxation contrast T1 in the rotating frame

scientific article published in April 2002

Editorial: Vascularization for Regenerative Medicine

scientific article published on 21 November 2018

Effect of adventitial VEGF(165) gene transfer on vascular thickening after coronary artery balloon injury

scientific article published in December 2003

Effect of post-mortem time on the biochemical composition of coronary arteries

scientific article

Effect of repeated endotoxin treatment and hypercholesterolemia on preatherosclerotic lesions in weaned pigs Part 1. Scanning and transmission electron microscopic study

article

Effect of repeated endotoxin treatment and hypercholesterolemia on preatherosclerotic lesions in weaned pigs Part 11. Lipid and glycosaminoglycan analysis of intima and inner media

Effect of vitamin E on endothelial vasodilator function in patients with hypercholesterolemia, chronic smoking or both.

scientific article

Effects of Age, Diet, and Type 2 Diabetes on the Development and FDG Uptake of Atherosclerotic Plaques

article

Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis

scientific article published on 17 February 2012

Effects of atorvastatin and diet interventions on atherosclerotic plaque inflammation and [ 18 F]FDG uptake in Ldlr −/− Apob 100/100 mice

Effects of linagliptin intervention on atherosclerotic plaque inflammation and 18F-FDG uptake in a mouse model of type 2 diabetes

Effects of liposome-encapsulated bisphosphonates on acetylated LDL metabolism, lipid accumulation and viability of phagocyting cells

scientific article

Effects of vaccinia virus anti-inflammatory protein 35K and TIMP-1 gene transfers on vein graft stenosis in rabbits

scientific article

Efficacy and safety of myocardial gene transfer of adenovirus, adeno-associated virus and lentivirus vectors in the mouse heart

scientific article published on 24 December 2015

Efficient adventitial gene delivery to rabbit carotid artery with cationic polymer-plasmid complexes

scientific article published in January 1999

Efficient gene therapy based targeting system for the treatment of inoperable tumors

scientific article

Efficient pro-survival/angiogenic miRNA delivery by an MRI-detectable nanomaterial.

scientific article

Efficient production of active chicken avidin using a bacterial signal peptide in Escherichia coli

scientific article published on December 2004

Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy

scientific article

Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer

scientific article

Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism

scientific article

Endgame: glybera finally recommended for approval as the first gene therapy drug in the European union

scientific article

Endostatin inhibits endochondral ossification

scholarly article by A Sipola published in January 2007

Endothelial 15-lipoxygenase-1 overexpression increases acetylcholine-induced hypotension and vasorelaxation in rabbits

scientific article published on 7 January 2008

Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat

scientific article published on 05 August 2016

Endothelial cell differentiation is encompassed by changes in long range interactions between inactive chromatin regions.

scientific article published on 4 December 2017

Endothelium-specific overexpression of human vascular endothelial growth factor-D in mice leads to increased tumor frequency and a reduced lifespan.

scientific article published in March 2012

Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein

scientific article published on 03 May 2007

Enhanced gene delivery by avidin-displaying baculovirus

scientific article published on February 2004

Enhanced plasma cholesterol lowering effect of retrovirus-mediated LDL receptor gene transfer to WHHL rabbit liver after improved surgical technique and stimulation of hepatocyte proliferation by combined partial liver resection and thymidine kinase

scientific article published in January 1999

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism

scientific article

Enhancing Angiogenesis in Mice by VEGF-Targeting Small Activating RNAs

scientific article published on January 2017

Enrichment of long-chain ω9 and ω6 fatty acids in arterial cholesteryl esters in the early phase of atherogenesis

Enterolactone induces heme oxygenase-1 expression through nuclear factor-E2-related factor 2 activation in endothelial cells.

scientific article

EphrinB2/EphB4 signaling regulates non-sprouting angiogenesis by VEGF.

scientific article published on 11 April 2018

Epigenetherapy, a new concept

scientific article published in June 2011

Epigenetic Epidemiology of Atherosclerosis

scholarly article published 1 November 2011

Epigenetic regulation in vascular cells

scientific article published on October 2013

Epigenetic regulation of key vascular genes and growth factors

scientific article published on 14 April 2011

Epigenetic upregulation of endogenous VEGF-A reduces myocardial infarct size in mice

scientific article

Epigenetics and Atherosclerosis

article published in 2012

Epigenetics and atherosclerosis

scientific article published on 21 February 2009

Epigenetics and atherosclerosis

Erratum: Long-term VEGF-A expression promotes aberrant angiogenesis and fibrosis in skeletal muscle

scholarly article published in Gene Therapy

Erratum: Periadventitial angiopoietin 1 gene transfer induces angiogenesis in rabbit carotid arteries

article

Escherichia coli DNA contamination in AmpliTaq Gold polymerase interferes with TaqMan analysis of lacZ.

scientific article

Evaluation and characterization of EIA measuring autoantibodies against oxidized LDL

scientific article published on 01 September 2001

Evaluation of alphavbeta3 integrin-targeted positron emission tomography tracer 18F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice

scientific article published on 13 May 2009

Evaluation of angiogenesis and side effects in ischemic rabbit hindlimbs after intramuscular injection of adenoviral vectors encoding VEGF and LacZ.

scientific article

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man

scientific article

Evolving revascularization approaches for myocardial ischemia

scientific article published in November 2003

Exosomes as secondary inductive signals involved in kidney organogenesis

scientific article published on 23 January 2018

Experimental hyperlipidaemia does not prevent preconditioning and it reduces ischemia-induced apoptosis.

scientific article

Expression of LDL receptor, VLDL receptor, LDL receptor-related protein, and scavenger receptor in rabbit atherosclerotic lesions: marked induction of scavenger receptor and VLDL receptor expression during lesion development

scientific article published on March 1998

Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and scavenger receptor in human atherosclerotic lesions

scientific article

Expression of extracellular SOD and iNOS in macrophages and smooth muscle cells in human and rabbit atherosclerotic lesions: colocalization with epitopes characteristic of oxidized LDL and peroxynitrite-modified proteins.

scientific article published on February 1998

Expression of inducible nitric oxide synthase in macrophages and smooth muscle cells in various types of human atherosclerotic lesions

scientific article published on 01 June 1999

Expression of lipoprotein receptors in atherosclerotic lesions ⬇️

scientific article published on April 1, 1998

Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions

scientific article published on June 1991

Expression of urokinase-type plasminogen activator receptor is increased during epileptogenesis in the rat hippocampus.

scientific article

Expression of vascular endothelial growth factor (VEGF)-B and its receptor (VEGFR1) in murine heart, lung and kidney

scientific article

Expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in ischemic skeletal muscle and its regeneration

scientific article published on April 2002

Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer.

scientific article published on 14 June 2019

Extended release of adenovirus from silica implants in vitro and in vivo

scientific article

Extracellular superoxide dismutase accelerates endothelial recovery and inhibits in-stent restenosis in stented atherosclerotic Watanabe heritable hyperlipidemic rabbit aorta.

scientific article published on 19 November 2007

Extracellular superoxide dismutase deficiency and atherosclerosis in mice

scientific article

Extracellular superoxide dismutase with vaccinia virus anti-inflammatory protein 35K or tissue inhibitor of metalloproteinase-1: Combination gene therapy in the treatment of vein graft stenosis in rabbits

scientific article published in April 2006

Extracellular vesicles provide a capsid-free vector for oncolytic adenoviral DNA delivery

scientific article published on 17 April 2020

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

scientific article

False-positive apoptosis signal in mouse kidney and liver detected with TUNEL assay

scientific article published on 01 October 2000

Feasibility of experimental BT4C glioma models for somatostatin receptor 2-targeted therapies

scientific article

Feline immunodeficiency virus and retrovirus-mediated adventitial ex vivo gene transfer to rabbit carotid artery using autologous vascular smooth muscle cells

scientific article published in March 2004

Fetal membranes act as a barrier for adenoviruses: gene transfer into exocoelomic cavity of rat fetuses does not affect cells in the fetus

scientific article published in January 2004

Fibroblast growth factor 4 induces vascular permeability, angiogenesis and arteriogenesis in a rabbit hindlimb ischemia model

scientific article published on 15 November 2002

From the impact factor to DORA and the scientific content of articles

scientific article

Functional genomics and DNA array techniques in atherosclerosis research

scientific article

Future directions for therapeutic strategies in post-ischaemic vascularization: a position paper from European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology

article

Future prospects and challenges of antiangiogenic cancer gene therapy

scientific article published on April 2010

Gamma-secretase inhibitor treatment promotes VEGF-A-driven blood vessel growth and vascular leakage but disrupts neovascular perfusion

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Gene Deliver y to Rabbit Arteries Using the Collar Model

scientific article published on January 1, 1999

Gene Editing of Human Embryos with CRISPR/Cas9: Great Promise Coupled with Important Caveats

scientific article published on 21 February 2018

Gene Expression in Macrophage-Rich Inflammatory Cell Infiltrates in Human Atherosclerotic Lesions as Studied by Laser Microdissection and DNA Array

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Gene Therapy Moves Forward in 2010 ⬇️

scientific article published on February 1, 2011

Gene Therapy Used in Cancer Treatment

scientific article published on 8 April 2014

Gene Therapy for Heart Failure: Back to the Bench

scientific article published on October 2015

Gene Therapy in Nordic Countries

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Gene and Cell Therapy: Success Stories and Future Challenges

scientific article published on 19 April 2019

Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: cloning, genomic structure, and screening for variants in patients with type 2 diabetes

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Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts

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Gene therapy for angiogenesis, restenosis and related diseases.

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Gene therapy for cardiovascular diseases

scientific article published on January 2004

Gene therapy for coronary heart disease

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Gene therapy for ischemic cardiovascular diseases: some lessons learned from the first clinical trials

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Gene therapy for malignant glioma: current clinical status

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Gene therapy for restenosis: current status

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Gene therapy for therapeutic angiogenesis in critically ischaemic lower limb - on the way to the clinic

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Gene therapy in age related macular degeneration and hereditary macular disorders

scientific article published on June 2012

Gene therapy methods in cardiovascular diseases

scientific article published on January 2002

Gene therapy to prevent occlusion of venous bypass grafts

scientific article published on June 2008

Gene therapy with vascular endothelial growth factors

scientific article published on December 2009

Gene therapy: the first approved gene-based medicines, molecular mechanisms and clinical indications

scientific article published on January 2008

Gene transfer as a tool to induce therapeutic vascular growth

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Gene transfer for therapeutic vascular growth in myocardial and peripheral ischemia

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Gene transfer into rabbit arteries with adeno-associated virus and adenovirus vectors.

scientific article published in May 2004

Gene transfer into the carotid artery using an adventitial collar: comparison of the effectiveness of the plasmid-liposome complexes, retroviruses, pseudotyped retroviruses, and adenoviruses

scientific article published in September 1997

Gene transfer of extracellular superoxide dismutase to atherosclerotic mice

scientific article published in June 2001

Gene transfer to human placenta ex vivo: a novel application of dual perfusion of human placental cotyledon

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Gene transfer using the mature form of VEGF-D reduces neointimal thickening through nitric oxide-dependent mechanism

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Gene transfer vectors (DNA vehicles) and their incorporation into biomaterials for bone repair

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Gene transfers of vascular endothelial growth factor-A, vascular endothelial growth factor-B, vascular endothelial growth factor-C, and vascular endothelial growth factor-D have no effects on atherosclerosis in hypercholesterolemic low-density lipop

scientific article published in August 2005

General principles and approaches of gene therapy

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Generation of lentivirus vectors using recombinant baculoviruses

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Genes involved in atherosclerosis

scientific article published on 01 January 2002

Genetic alterations in the peritumoral stromal cells of malignant and borderline epithelial ovarian tumors as indicated by allelic imbalance on chromosome 3p.

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Genetics, genomics and proteomics in atherosclerosis research

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Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial Infarction

scientific article published in June 2017

Glioma cell density in a rat gene therapy model gauged by water relaxation rate along a fictitious magnetic field

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Global DNA methylation analysis of human atherosclerotic plaques reveals extensive genomic hypomethylation and reactivation at imprinted locus 14q32 involving induction of a miRNA cluster

scientific article

Glybera's second act: the curtain rises on the high cost of therapy

scientific article published on February 2015

Granulocyte transmigration through the endothelium is regulated by the oxidase activity of vascular adhesion protein-1 (VAP-1).

scientific article published on 15 January 2004

Growth Factor Therapy and Autologous Lymph Node Transfer in Lymphedema

Growth factor therapy and lymph node graft for lymphedema.

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Growth factor-induced therapeutic angiogenesis and arteriogenesis in the heart--gene therapy

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HIF-1 induction attenuates Nrf2-dependent IL-8 expression in human endothelial cells

scientific article published in July 2009

HIF-1α and HIF-2α induce angiogenesis and improve muscle energy recovery

scientific article published in October 2014

HIF-VEGF-VEGFR-2, TNF-alpha and IGF pathways are upregulated in critical human skeletal muscle ischemia as studied with DNA array

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HSV-tk gene therapy for human renal cell carcinoma in nude mice

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Heme oxygenase 1 is induced by miR-155 via reduced BACH1 translation in endothelial cells

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Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reactions

scientific article published in March 2000

High Plasma Lipid Levels Reduce Efficacy of Adenovirus-Mediated Gene Therapy

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High expression of Tie-2 predicts poor prognosis in primary high grade serous ovarian cancer

scientific article published on 05 November 2020

High expression of human 15-lipoxygenase induces NF-kappaB-mediated expression of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and T-cell adhesion on human endothelial cells

scientific article published on January 1999

High-resolution ultrasound perfusion imaging of therapeutic angiogenesis

scientific article published on January 2008

Highlighting the Field of Cardiovascular Regenerative Medicine

scientific article published on 19 June 2018

History of gene therapy

scientific article published on 23 April 2013

How to avoid complement attack in baculovirus-mediated gene delivery

scientific article published on July 2011

Human Vascular Endothelial Growth Factor A Expression Induces the Mouse Model of Neovascular Age-Related Macular Degeneration

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Human gene therapy and imaging: cardiology

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Hyperbaric oxygen therapy activates hypoxia-inducible factor 1 (HIF-1), which contributes to improved wound healing in diabetic mice.

scientific article published in January 2015

Hypoxia and platelet-derived growth factor-BB synergistically upregulate the expression of vascular endothelial growth factor in vascular smooth muscle cells

scientific article published on 01 January 1995

Hypoxia induces microRNA miR-210 in vitro and in vivo ephrin-A3 and neuronal pentraxin 1 are potentially regulated by miR-210.

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Hypoxia-inducible factor 1-induced G protein-coupled receptor 35 expression is an early marker of progressive cardiac remodelling

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Imaging of αvβ3 integrin expression in experimental myocardial ischemia with [68Ga]NODAGA-RGD positron emission tomography

scientific article published on 19 June 2017

Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas

scientific article published on 3 August 2017

Improved gene transfer efficiency in liver with vesicular stomatitis virus G-protein pseudotyped retrovirus after partial liver resection and thymidine kinase-ganciclovir pre-treatment

scientific article published in November 1999

Improved generation of recombinant baculovirus genomes in Escherichia coli

scientific article published in September 2003

Improved therapeutic effect on malignant glioma with adenoviral suicide gene therapy combined with temozolomide

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Improvement in adenoviral gene transfer efficiency after preincubation at +37 degrees C in vitro and in vivo

scientific article published on January 2002

Improvement in nuclear entry and transgene expression of baculoviruses by disintegration of microtubules in human hepatocytes

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Improving safety of gene therapy

scientific article published on January 2008

In Vivo Low Density Lipoprotein Oxidation Relates to Coronary Reactivity in Young Men

scientific article published on 01 July 1997

In vitro targeting of avidin-expressing glioma cells with biotinylated persistent luminescence nanoparticles

scientific article published on 7 February 2012

In vivo SPECT/CT imaging of human orthotopic ovarian carcinoma xenografts with 111In-labeled monoclonal antibodies

scientific article published on November 2010

In vivo application and tracking of baculovirus

scientific article published on June 2010

In vivo inhibition of nuclear factor of activated T-cells leads to atherosclerotic plaque regression in IGF-II/LDLR-/-ApoB100/100 mice

scientific article published in March 2018

In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin-1-p150Glued

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Increased Atherosclerotic Lesion Calcification in a Novel Mouse Model Combining Insulin Resistance, Hyperglycemia, and Hypercholesterolemia

scientific article published on 13 September 2007

Increased invasion of malignant gliomas after 15-LO-1 and HSV-tk/ganciclovir combination gene therapy

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Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomized, placebo-controlled, double-blinded phase II study

scientific article published on July 2002

Induction of 15-lipoxygenase mRNA and protein in early atherosclerotic lesions

scientific article published on December 1995

Inhibition of basal and interleukin-1-induced VCAM-1 expression by phospholipid hydroperoxide glutathione peroxidase and 15-lipoxygenase in rabbit aortic smooth muscle cells

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Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3.

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Inhibition of urothelial carcinoma through targeted type I interferon-mediated immune activation

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Insights into the molecular pathogenesis of atherosclerosis and therapeutic strategies using gene transfer

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Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies

scientific article published on January 1999

Intestinal lymphatic vessels and their role in chylomicron absorption and lipid homeostasis

scientific article published on 01 October 2019

Intracardiac injection of a capsid-modified Ad5/35 results in decreased heart toxicity when compared to standard Ad5

scientific article published on 29 November 2012

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

scientific article published on 10 September 2009

Intramyocardial Gene Therapy Directed to Hibernating Heart Muscle Using a Combination of Electromechanical Mapping and Positron Emission Tomography

scientific article published on 23 August 2016

Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta

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Intravascular adenovirus-mediated lipoprotein-associated phospholipase A2 gene transfer reduces neointima formation in balloon-denuded rabbit aorta

Intravascular ultrasound and magnetic resonance imaging in the assessment of atherosclerotic lesions in rabbit aorta. Correlation to histopathologic findings

scientific article published in August 1998

Intravesical rAd-IFNα/Syn3 for Patients With High-Grade, Bacillus Calmette-Guerin-Refractory or Relapsed Non-Muscle-Invasive Bladder Cancer: A Phase II Randomized Study

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Intravitreal adenoviral 15-lipoxygenase-1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes

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Involvement of specific macrophage-lineage cells surrounding arterioles in barrier and scavenger function in brain cortex

scientific article published on April 1996

Is oxidized low‐density lipoprotein present in vivo? ⬇️

scientific article published on 01 August 1998

Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart

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Isolation of fresh endothelial cells from porcine heart for cardiovascular studies: a new fast protocol suitable for genomic, transcriptomic and cell biology studies

scientific article published on 13 August 2019

KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells

scientific article published on 8 May 2008

LDLR-/-ApoB100/100 mice with insulin-like growth factor II overexpression reveal a novel form of retinopathy with photoreceptor atrophy and altered morphology of the retina ⬇️

scientific article published on 04 August 2013

Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice.

scientific article published on 29 August 2014

Left ventricular dysfunction with reduced functional cardiac reserve in diabetic and non-diabetic LDL-receptor deficient apolipoprotein B100-only mice

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Left ventricular remodeling leads to heart failure in mice with cardiac-specific overexpression of VEGF-B167: echocardiography and magnetic resonance imaging study.

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Lentiviral protein transduction with genome-modifying HIV-1 integrase-I-PpoI fusion proteins: studies on specificity and cytotoxicity

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Leukocyte trafficking-associated vascular adhesion protein 1 is expressed and functionally active in atherosclerotic plaques

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Linked Chromosome 16q13 Chemokines, Macrophage-Derived Chemokine, Fractalkine, and Thymus- and Activation-Regulated Chemokine, Are Expressed in Human Atherosclerotic Lesions

scientific article published on 01 June 2001

Lipid accumulation, lipid oxidation, and low plasma levels of acquired antibodies against oxidized lipids associate with degeneration and rupture of the intracranial aneurysm wall

scientific article published on 28 October 2013

Lipoprotein-Associated Phospholipase A 2 , Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions

scientific article published on 01 December 1999

Lipoproteins in normal and atherosclerotic aorta

scientific article published on August 1990

Local adventitial anti-angiogenic gene therapy reduces growth of vasa-vasorum and in-stent restenosis in WHHL rabbits

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Local hypomethylation in atherosclerosis found in rabbit ec-sod gene

scientific article published in September 1999

Localization of M2 muscarinic receptor protein in parvalbumin and calretinin containing cells of the adult rat entorhinal cortex using two complementary methods

scientific article published in January 2005

Long Non-Coding RNA Modulation of VEGF-A during Hypoxia

scientific article published on 20 November 2018

Long-term VEGF-A expression promotes aberrant angiogenesis and fibrosis in skeletal muscle

scientific article published on 12 May 2011

Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy

scientific article published in April 2004

Longitudinal rotating frame relaxation time measurements in infarcted mouse myocardium in vivo

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Low density lipoprotein undergoes oxidative modification in vivo

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Low efficacy of gene therapy for rat BT4C malignant glioma using intra-tumoural transduction with thymidine kinase retrovirus packaging cell injections and ganciclovir treatment

scientific article published in January 1999

Low interleukin-2 concentration favors generation of early memory T cells over effector phenotypes during chimeric antigen receptor T-cell expansion

scientific article published on 11 April 2017

Low interleukin-2 concentration favors generation of early memory T cells over effector phenotypes during chimeric antigen receptor T-cell expansion

scientific article published on 20 June 2017

Low spin-lock field T1 relaxation in the rotating frame as a sensitive MR imaging marker for gene therapy treatment response in rat glioma

scientific article

Low-grade inflammation and the phenotypic expression of myocardial fibrosis in hypertrophic cardiomyopathy

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Lymph node transfer and perinodal lymphatic growth factor treatment for lymphedema

scientific article

Lymphangiogenic gene therapy with minimal blood vascular side effects

scientific article

Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation

scientific article published on August 2006

Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor

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Lymphatic vasculature is increased in heart valves, ischaemic and inflamed hearts and in cholesterol-rich and calcified atherosclerotic lesions

scientific article published on 03 December 2010

Lymphatic vessel insufficiency in hypercholesterolemic mice alters lipoprotein levels and promotes atherogenesis.

scientific article

Macrophage colony-stimulating factor mRNA and protein in atherosclerotic lesions of rabbits and humans ⬇️

scientific article published on February 1, 1992

Macrophage foam cells from human aortic fatty streaks take up beta-VLDL and acetylated LDL in primary culture

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Macrophage selective photodynamic therapy by meta-tetra(hydroxyphenyl)chlorin loaded polymeric micelles: A possible treatment for cardiovascular diseases

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Macrophages and Oxidized Low Density Lipoproteins in the Pathogenesis of Atherosclerosis ⬇️

scientific article published on January 1, 1991

Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions ⬇️

scientific article published on November 15, 1991

Macrophages, endothelial cells, and lipoprotein oxidation in the pathogenesis of atherosclerosis

scientific article published on January 1990

Magnetic resonance imaging of viral particle biodistribution in vivo.

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Magnetically Coated Bioabsorbable Stents for Renormalization of Arterial Vessel Walls after Stent Implantation.

scientific article published on 22 December 2017

Metabolism of modified LDL and foam cell formation in murine macrophage-like RAW 264 cells

scientific article published on January 1999

Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro.

scientific article

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

scientific article published on 28 September 2020

Modified RNA kick-starts cardiac repair

scientific article published in October 2013

Molecular Therapy Special Issue on Gene Editing Technologies and Applications

scientific article published on August 2015

Molecular genetics of atherosclerosis

scientific article published on 20 March 2009

Monitoring of lipoprotein oxidation by gas chromatographic analysis of hydroxy fatty acids

scientific article published on 01 January 1995

Morphological characterization of baculovirus Autographa californica multiple nucleopolyhedrovirus

scientific article published on 05 December 2009

Mouse ECG findings in aging, with conduction system affecting drugs and in cardiac pathologies: Development and validation of ECG analysis algorithm in mice

scientific article published on December 2015

Neuropilin-2 and vascular endothelial growth factor receptor-3 are up-regulated in human vascular malformations

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New Technologies in Cardiovascular Research: Gene Therapy

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New aspects in vascular gene therapy

scientific article published on 15 February 2010

Nitric oxide donor GEA 3162 inhibits endothelial cell-mediated oxidation of low density lipoprotein

scientific article published on 01 January 1994

Non-invasive Imaging in Gene Therapy

scientific article published on 19 June 2007

Non-specific binding of [18F]FDG to calcifications in atherosclerotic plaques: experimental study of mouse and human arteries

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Nonviral gene delivery methods in cardiovascular diseases

scientific article published on 01 January 2005

Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor.

scientific article published on 12 May 2011

Novel insights into the regulation of antioxidant-response-elementmediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2

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Novel magnetic resonance imaging contrasts for monitoring response to gene therapy in rat glioma

scientific article published in November 2003

Novel targeting of biotinylated compounds to local tissues with avidin-lipoprotein receptor fusion protein.

scientific article published in December 2003

Novel vascular endothelial growth factor D variants with increased biological activity

scientific article published on 14 April 2009

Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo

scientific article published on 25 January 2007

Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo

scientific article published on 5 June 2008

Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid

scientific article published on 05 October 2009

Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice

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Nuclear factor erythroid 2-related factor 2 protects against beta amyloid.

scientific article published on 29 July 2008

On the relationship of LDL and VEGFR1: not just a family affair

scientific article published on December 2007

Optimization of lentiviral vector production for scale-up in fixed-bed bioreactor

scientific article published on 5 October 2017

Optimized in situ PCR method for the detection of gene transfer vector in histological sections

scientific article published in March 2001

Optimized self-excising Cre-expression cassette for mammalian cells

scientific article published on July 2004

Oral imatinib mesylate (STI571/gleevec) improves the efficacy of local intravascular vascular endothelial growth factor-C gene transfer in reducing neointimal growth in hypercholesterolemic rabbits

scientific article published on 9 February 2004

Overexpression of PHGPx inhibits hydroperoxide-induced oxidation, NFkappaB activation and apoptosis and affects oxLDL-mediated proliferation of rabbit aortic smooth muscle cells

scientific article published in October 2000

Overexpression of VEGF-A induces neovascularization and increased vascular leakage in rabbit eye after intravitreal adenoviral gene transfer

scientific article published in August 2006

Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy

scientific article published on 28 August 2008

Oxidation of LDL by rabbit and human 15-lipoxygenase: prevalence of nonenzymatic reactions.

scientific article published in July 2001

Oxidative stress-inducible lentiviral vectors for gene therapy.

scientific article published in May 2008

Oxidative stress-regulated lentiviral TK/GCV gene therapy for lung cancer treatment

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Oxidized LDL and atherogenesis

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Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

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Oxysterol binding protein induces upregulation of SREBP-1c and enhances hepatic lipogenesis.

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PDGF-C and -D and their receptors PDGFR-alpha and PDGFR-beta in atherosclerotic human arteries

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Pathogenesis and treatment of atherosclerosis-related diseases

Pathogenesis of atherosclerosis

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Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.

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Patterns of oxidized epitopes, but not NF-kappa B expression, change during atherogenesis in WHHL rabbits

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Peptide-Retargeted Adenovirus Encoding a Tissue Inhibitor of Metalloproteinase-1 Decreases Restenosis after Intravascular Gene Transfer

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Percutaneous transcoronary venous access for cellular cardiomyoplasty ⬇️

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Periadventitial angiopoietin-1 gene transfer induces angiogenesis in rabbit carotid arteries

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Periadventitial lacZ gene transfer to pig carotid arteries using a biodegradable collagen collar or a wrap of collagen sheet with adenoviruses and plasmid-liposome complexes

scientific article published in January 2000

Peroxisome proliferator-activated receptor-γ coactivator 1 α1 induces a cardiac excitation-contraction coupling phenotype without metabolic remodelling

scientific article published on 26 September 2016

Phosphorylation regulates FOXC2-mediated transcription in lymphatic endothelial cells

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Photodynamic Ablation of Lymphatic Vessels and Intralymphatic Cancer Cells Prevents Metastasis

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Platelet-derived Growth Factor-B Protects Rat Cardiac Allografts From Ischemia-reperfusion Injury

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Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with 18F-GE-180, a Radiotracer for Translocator Protein (TSPO).

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Positron emission tomography tracer [68GA]NODAGA-EXENDIN-4 detects glucagon-like peptide-1 receptor expression in mouse atherosclerotic vascular lesions

Post-intervention vessel remodeling

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Post-transcriptional regulatory element boosts baculovirus-mediated gene expression in vertebrate cells

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Postmenopausal hormone replacement therapy and autoantibodies against oxidized LDL.

scientific article published in June 1998

Preclinical Proof-of-Concept, Analytical Development, and Commercial Scale Production of Lentiviral Vector in Adherent Cells

scientific article published on 29 August 2019

Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer

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Preoperative angiopoietin-2 serum levels: a marker of malignant potential in ovarian neoplasms and poor prognosis in epithelial ovarian cancer

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Preparation of recombinant baculoviruses with the BVboost system

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Primary and metastatic ovarian cancer: Characterization by 3.0T diffusion-weighted MRI.

scientific article published on 13 March 2017

Primary effect of 1α,25(OH)₂D₃ on IL-10 expression in monocytes is short-term down-regulation

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Pro- and anti-angiogenic therapy and atherosclerosis with special emphasis on vascular endothelial growth factors

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Process Development of Adenoviral Vector Production in Fixed Bed Bioreactor: From Bench to Commercial Scale

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Production and purification of lentiviral vectors generated in 293T suspension cells with baculoviral vectors

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Production of HIV-1 integrase fusion protein-carrying lentiviral vectors for gene therapy and protein transduction

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Production of functional recombinant tyrosine hydroxylase by the BPV-1 expression plasmids in the cell cultures

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Profiling of Primary and Mature miRNA Expression in Atherosclerosis-Associated Cell Types

scientific article published on 13 May 2021

Progress and prospects: gene therapy clinical trials (part 1).

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Progress and prospects: hurdles to cardiovascular gene therapy clinical trials

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Promoter polymorphisms -359T/C and -303A/G of the catalytic subunit p110beta gene of human phosphatidylinositol 3-kinase are not associated with insulin secretion or insulin sensitivity in finnish subjects

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Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success

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Prospect and progress of gene therapy in treating atherosclerosis

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Prox1 interacts with Atoh1 and Gfi1, and regulates cellular differentiation in the inner ear sensory epithelia

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Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

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Quantification of porcine myocardial perfusion with modified dual bolus MRI - a prospective study with a PET reference

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Quantitative 1H nuclear magnetic resonance diffusion spectroscopy of BT4C rat glioma during thymidine kinase-mediated gene therapy in vivo: identification of apoptotic response

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Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL.

scientific article published in January 1994

Rabbit atherosclerotic lesions express scavenger receptor AIII mRNA, a naturally occurring splice variant that encodes a non-functional, dominant negative form of the macrophage scavenger receptor

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Rabbit extracellular superoxide dismutase: expression and effect on LDL oxidation

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Recent Advancements in Cardiovascular Gene Therapy and Vascular Biology

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Recent advances in novel therapies for lipid disorders

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Receptor-mediated binding and degradation of subfractions of human plasma low-density lipoprotein by cultured fibroblasts

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Regulation of VEGF-A Expression in Endothelial Cells by Transcriptional Gene Activation or Transcriptional Gene Silencing: Analysis of Genome Wide Transcriptional Response

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Regulation of endothelial lipase and systemic HDL cholesterol levels by SREBPs and VEGF-A.

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Release of replication-deficient retroviruses from a packaging cell line: interaction with glioma tumor spheroids in vitro

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Relevance of an academic GMP Pan-European vector infra-structure (PEVI).

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Reply to "heparan sulfate in baculovirus binding and entry of Mammalian cells".

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Reply to Kerbel et al.: EPCs are again claimed to be essential in yet other models despite the irreproducibility of the original experiments introducing them

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Requirements for baculoviruses for clinical gene therapy applications

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Research update for articles published in EJCI in 2011

Resectable VX-2 rabbit brain tumor model for development of intraoperative local administration of drugs

scientific article published on 18 June 2011

Residual adverse changes in arterial endothelial function and LDL oxidation after a mild systemic inflammation induced by influenza vaccination

scientific article published on 01 January 2007

Respiratory infection recurrence and passive smoking in early atherosclerosis in children and adolescents with type 1 diabetes

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Retrovirus-mediated, stable scavenger-receptor gene transfer leads to functional endocytotic receptor expression, foam cell formation, and increased susceptibility to apoptosis in rabbit aortic smooth muscle cells

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Review focus on epigenetics and the histone code in vascular biology

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Rhizavidin from Rhizobium etli: the first natural dimer in the avidin protein family

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Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)

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SPECT/CT imaging of baculovirus biodistribution in rat.

scientific article published on 5 April 2007

SUR1-E1506K mutation impairs glucose tolerance and promotes vulnerable atherosclerotic plaque phenotype in hypercholesterolemic mice

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Safety and Feasibility of Catheter-Based Local Intracoronary Vascular Endothelial Growth Factor Gene Transfer in the Prevention of Postangioplasty and In-Stent Restenosis and in the Treatment of Chronic Myocardial Ischemia ⬇️

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Safety profile of plasmid/liposomes and virus vectors in clinical gene therapy

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Screening of complement inhibitors: shielded baculoviruses increase the safety and efficacy of gene delivery

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Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease

scientific article published on 01 October 1995

Serial Optical Coherence Tomography at Baseline, 7 Days, and 1, 3, 6 and 12 Months After Bioresorbable Scaffold Implantation in a Growing Porcine Model

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Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer

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Severe coronary artery stenoses and reduced coronary flow velocity reserve in atherosclerotic mouse model

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Short and long-term effects of hVEGF-A(165) in Cre-activated transgenic mice

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Silencing of either SR-A or CD36 reduces atherosclerosis in hyperlipidaemic mice and reveals reciprocal upregulation of these receptors

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Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2.

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Sleeping Beauty Transposon Vectors in Liver-directed Gene Delivery of LDLR and VLDLR for Gene Therapy of Familial Hypercholesterolemia

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Sleeping Beauty-baculovirus hybrid vectors for long-term gene expression in the eye.

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Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle via reduced eNOS activity

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Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions

Smooth Muscle Cell Foam Cell Formation, Apolipoproteins, and ABCA1 in Intracranial Aneurysms: Implications for Lipid Accumulation as a Promoter of Aneurysm Wall Rupture

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Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling

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Soluble vascular endothelial growth factor receptor-1 improves therapeutic efficacy of suicide gene therapy in an angiogenesis-independent manner

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Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain

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Specific inhibition of SRC kinase impairs malignant glioma growth in vitro and in vivo

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Stabilisation of atherosclerotic plaques

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Stabilization of HIF-1alpha is critical to improve wound healing in diabetic mice

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Stabilization of atherosclerotic plaques: an update

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Stabilized HIF-1alpha is superior to VEGF for angiogenesis in skeletal muscle via adeno-associated virus gene transfer

scientific article published on 15 June 2005

Stable RNA interference: comparison of U6 and H1 promoters in endothelial cells and in mouse brain.

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Stimulation of functional vessel growth by gene therapy

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Structural determinants of vascular endothelial growth factor-D receptor binding and specificity

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Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells

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Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.

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TAFFEL: Independent Enrichment Analysis of gene sets

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Targeted delivery via avidin fusion protein: intracellular fate of biotinylated doxorubicin derivative and cellular uptake kinetics and biodistribution of biotinylated liposomes

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Targeted magnetic resonance imaging of Scavidin-receptor in human umbilical vein endothelial cells in vitro

scientific article published in April 2006

Targeting and purification of metabolically biotinylated baculovirus

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Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts.

scientific article published on 15 March 2010

Targeting of biotinylated compounds to its target tissue using a low-density lipoprotein receptor-avidin fusion protein

scientific article published in December 2003

Temporal Dynamics of Gene Expression During Endothelial Cell Differentiation From Human iPS Cells: A Comparison Study of Signalling Factors and Small Molecules

scientific article published on 14 March 2018

The Need for Increased Clarity and Transparency in the Regulatory Pathway for Gene Medicines in the European Union ⬇️

scientific article published on March 1, 2012

The Pharmacology of Gene Therapy

scientific article published on 22 July 2017

The Strengths and Weaknesses of VEGF Adenovirus-Driven Angiogenesis

The Syngeneic BT4C Rat Malignant Glioma is a Valuable Model to study Myelomonocytic cells in Tumors

The absence of macrophage Nrf2 promotes early atherogenesis

scientific article published on 22 January 2013

The administration of an adenoviral thymidine kinase suicide gene to the uterine artery of rabbits does not affect fertility: a safety study of pregnant and nonpregnant rabbits and their offspring

scientific article

The atherosclerotic lesion: a dynamic landscape

scientific article published on 01 October 1998

The bottleneck stent model for chronic myocardial ischemia and heart failure in pigs

scientific article

The combination of HSV-tk and endostatin gene therapy eradicates orthotopic human renal cell carcinomas in nude mice

scientific article published in November 2002

The development of interferon-based gene therapy for BCG unresponsive bladder cancer: from bench to bedside

scientific article published on 11 November 2018

The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction: rationale and design of the BAMI trial.

scientific article published on 25 September 2017

The effect of proteoglycans, collagen and lysyl oxidase on the metabolism of low density lipoprotein by macrophages

scientific article published on 01 October 1986

The effect of subcellular localization on the efficiency of EGFR-targeted VHH photosensitizer conjugates

scientific article published on 20 December 2017

The effects of VEGF-A on atherosclerosis, lipoprotein profile, and lipoprotein lipase in hyperlipidaemic mouse models

scientific article

The effects of VEGF-R1 and VEGF-R2 ligands on angiogenic responses and left ventricular function in mice

scientific article

The follow-up of progressive hypertrophic cardiomyopathy using magnetic resonance rotating frame relaxation times

scientific article

The genetic and metabolic determinants of cardiovascular complications in type 2 diabetes: recent insights from animal models and clinical investigations

scientific article published on October 2013

The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features

scholarly article by Tiina Nieminen published in January 2014

The molecular therapy family: past, present, and future

scientific article published on January 2015

The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis

scientific article published in June 2008

The use of low-molecular-weight PEIs as gene carriers in the monkey fibroblastoma and rabbit smooth muscle cell cultures

scientific article

Therapeutic angiogenesis with placental growth factor improves exercise tolerance of ischaemic rabbit hindlimbs

scientific article

Therapeutic delivery using gene-delivery methods

scientific article

Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation.

scientific article published on 2 December 2007

Therapeutic effects of rosuvastatin in hypercholesterolemic prediabetic mice in the absence of low density lipoprotein receptor

scientific article published on 30 November 2018

Therapeutic gene targeting approaches for the treatment of dyslipidemias and atherosclerosis

scientific article published on April 2013

Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses

scientific article published on November 2000

Tie1 controls angiopoietin function in vascular remodeling and inflammation

scientific article

Tissue inhibitor of metalloproteinase 1 adenoviral gene therapy alone is equally effective in reducing restenosis as combination gene therapy in a rabbit restenosis model

scientific article published on 19 July 2005

Tomato thymidine kinase-based suicide gene therapy for malignant glioma--an alternative for Herpes Simplex virus-1 thymidine kinase

scientific article

Transcriptional Profiling of Hypoxia-Regulated Non-coding RNAs in Human Primary Endothelial Cells

scientific article published on 05 November 2018

Transduction of vertebrate cells with recombinant baculovirus

scientific article

Transduction patterns and efficiencies in rabbit uterine tissues after intraluminal uterine adenovirus administration vary with the reproductive cycle

scientific article published in January 2007

Transfection of oocytes and other types of ovarian cells in rabbits after direct injection into uterine arteries of adenoviruses and plasmid/liposomes.

scientific article

Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidized low density lipoprotein

scientific article published on June 1995

Transplantation of adipose tissue mesenchymal cells conjugated with VEGF-releasing microcarriers promotes repair in murine myocardial infarction.

scientific article published on 17 July 2015

Truncated vesicular stomatitis virus G protein improves baculovirus transduction efficiency in vitro and in vivo

scientific article

Tumor suppressor and growth regulatory genes are overexpressed in severe early-onset preeclampsia--an array study on case-specific human preeclamptic placental tissue

scientific article published in July 2005

Two Decades of Molecular Therapy: The Journey Continues

scholarly article by Robert M Frederickson & Seppo Ylä-Herttuala published 2 January 2019 in Molecular Therapy

Type 2 diabetes enhances arterial uptake of choline in atherosclerotic mice: an imaging study with positron emission tomography tracer ¹⁸F-fluoromethylcholine

scientific article published on 6 February 2016

Type I interferon response against viral and non-viral gene transfer in human tumor and primary cell lines

scientific article published on February 2007

Ultrasound imaging with bolus delivered contrast agent for the detection of angiogenesis and blood flow irregularities

scientific article

Umbilical cord blood-derived progenitor cells enhance muscle regeneration in mouse hindlimb ischemia model

scientific article published on 18 September 2007

Upregulated signaling pathways in ruptured human saccular intracranial aneurysm wall: an emerging regulative role of Toll-like receptor signaling and nuclear factor-κB, hypoxia-inducible factor-1A, and ETS transcription factors

scientific article

Uptake of 11C-choline in mouse atherosclerotic plaques

scientific article published on 15 April 2010

Uptake of 68gallium in atherosclerotic plaques in LDLR-/-ApoB100/100 mice

scientific article published on 17 August 2011

Uptake of inflammatory cell marker [11C]PK11195 into mouse atherosclerotic plaques

scientific article published on 19 August 2008

VEGF Gene Transfer Reduces Intimal Thickening via Increased Production of Nitric Oxide in Carotid Arteries

article

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

scientific article

VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis.

scientific article

VEGF-A, VEGF-D and VEGF-D(DeltaNDeltaC) induced intimal hyperplasia in carotid arteries

scientific article published in November 2005

VEGF-A, VEGF-D, VEGF receptor-1, VEGF receptor-2, NF-κB, and RAGE in atherosclerotic lesions of diabetic Watanabe heritable hyperlipidemic rabbits

scientific article published on 25 August 2006

VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

scientific article

VEGF-C and VEGF-C156S in the pro-lymphangiogenic growth factor therapy of lymphedema: a large animal study

scientific article published on 28 May 2015

VEGF-C induced angiogenesis preferentially occurs at a distance from lymphangiogenesis.

scientific article published on 07 December 2007

VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses

scientific article (publication date: 30 May 2003)

VEGF-DdeltaNdeltaC mediated angiogenesis in skeletal muscles of diabetic WHHL rabbits

scientific article published in May 2010

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.

scientific article published on 11 September 2011

Vascular Endothelial Growth Factor-B Induces a Distinct Electrophysiological Phenotype in Mouse Heart

scientific article

Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels

scientific article published on June 2005

Vascular endothelial growth factor (VEGF) gene transfer enhances surgical revascularization of necrotic bone

article

Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects.

scientific article

Vascular endothelial growth factor B controls endothelial fatty acid uptake.

scientific article published on 14 March 2010

Vascular endothelial growth factor C-induced collateral formation in a model of myocardial ischemia

scientific article published on 9 December 2005

Vascular endothelial growth factor enhances cardiac allograft arteriosclerosis.

scientific article published in May 2002

Vascular endothelial growth factor-A and platelet-derived growth factor-B combination gene therapy prolongs angiogenic effects via recruitment of interstitial mononuclear cells and paracrine effects rather than improved pericyte coverage of angiogen

scientific article published on 2 October 2008

Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment.

scientific article

Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation

scientific article published on 11 October 2010

Vascular endothelial growth factor-B gene transfer prevents angiotensin II-induced diastolic dysfunction via proliferation and capillary dilatation in rats

scientific article published on 23 August 2010

Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1- and neuropilin receptor-1-dependent mechanisms

scientific article published on 2 February 2009

Vascular endothelial growth factor-C accelerates diabetic wound healing

scientific article

Vascular endothelial growth factor-C gene therapy restores lymphatic flow across incision wounds.

scientific article

Vascular endothelial growth factor-D expression in human atherosclerotic lesions

scientific article published on 01 October 2003

Vascular endothelial growth factor-D transgenic mice show enhanced blood capillary density, improved postischemic muscle regeneration, and increased susceptibility to tumor formation

scientific article published on 10 December 2008

Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis

scientific article published on January 2013

Vascular endothelial growth factors in retinal and choroidal neovascular diseases

scientific article published on February 2011

Vascular endothelial growth factors: biology and current status of clinical applications in cardiovascular medicine

scientific article published on 23 February 2007

Vascular gene transfer for the treatment of restenosis and atherosclerosis

scientific article published in October 1998

Vascular oligonucleotide transfer facilitated by a polymer-coated stent

scientific article

Water diffusion in a rat glioma during ganciclovir-thymidine kinase gene therapy-induced programmed cell death in vivo: correlation with cell density.

scientific article

Water spin dynamics during apoptotic cell death in glioma gene therapy probed by T1rho and T2rho

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What have we learnt about microarray analyses of atherogenesis?

scientific article

Writing the Next Chapter for the Molecular Therapy Family of Journals

scientific article published on October 2016

[18F]fluorodeoxyglucose uptake in atherosclerotic plaques is associated with reduced coronary flow reserve in mice

scientific article published in November 2014

[How to make scar tissue in cardiac muscle beat?]

scientific article published on 01 January 2005

[Human gene therapy]

scientific article published in January 1996

lacZ-neoR transfected glioma cells in syngeneic rats: growth pattern and characterization of the host immune response against cells transplanted inside and outside the CNS.

scientific article

rDNA-directed integration by an HIV-1 integrase--I-PpoI fusion protein

scientific article published on 28 December 2012

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