List of works - Dionisios Vourloumis

3,4-diaminobenzoic acid derivatives as inhibitors of the oxytocinase subfamily of M1 aminopeptidases with immune-regulating properties

scientific article

A Homo sapiens cytoplasmic ribosomal decoding A-site affinity screen evaluating aminoglycoside and analogue binding ⬇️

scientific article published on January 14, 2011

A zebrafish in vivo phenotypic assay to identify 3-aminothiophene-2-carboxylic acid-based angiogenesis inhibitors

scientific article

Aminoglycoside-hybrid ligands targeting the ribosomal decoding site

scientific article published on 01 January 2005

Chemical Biology of Epothilones

scientific article published on 01 August 1998

Cobalt-Assisted Claisen Rearrangement of Enediyne Lactones at Ambient Temperature. Studies toward a Synthetic Application of the Myers Cycloaromatization

scientific article

Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.

scientific article published on 24 March 2011

Conformational dynamics of the EGFR kinase domain reveals structural features involved in activation.

scientific article

Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency.

scientific article published on 21 February 2017

Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells

Designed spiro-bicyclic analogues targeting the ribosomal decoding center

scientific article published on 01 January 2011

Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes.

scientific article published on 11 February 2010

Discovery of potent vascular endothelial growth factor receptor-2 inhibitors

scientific article

Exploration of zinc-binding groups for the design of inhibitors for the oxytocinase subfamily of M1 aminopeptidases

scientific article published on 01 November 2019

Heterometallic In(III)–Pd(II) Porous Metal–Organic Framework with Square-Octahedron Topology Displaying High CO2 Uptake and Selectivity toward CH4 and N2

scientific article published on 05 June 2018

Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody-Drug Conjugates.

scientific article

Molecular recognition by glycoside pseudo base pairs and triples in an apramycin-RNA complex

scientific article published in April 2005

Monitoring molecular recognition of the ribosomal decoding site

scientific article

Novel 2,5-dideoxystreptamine derivatives targeting the ribosomal decoding site RNA.

scientific article published in December 2002

Novel acyclic deoxystreptamine mimetics targeting the ribosomal decoding site

scientific article published in September 2003

Novel copper(II) complex of N-propyl-norfloxacin and 1,10-phenanthroline with enhanced antileukemic and DNA nuclease activities

scientific article published on 19 January 2008

Novel paromamine derivatives exploring shallow-groove recognition of ribosomal-decoding-site RNA

scientific article published on 01 December 2002

Novel selective inhibitors of aminopeptidases that generate antigenic peptides.

scientific article published on 23 July 2013

Piperidine glycosides targeting the ribosomal decoding site.

scientific article

Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides.

scientific article published on April 2011

Rational design of azepane-glycoside antibiotics targeting the bacterial ribosome

scientific article published in February 2004

Rigid spiroethers targeting the decoding center of the bacterial ribosome

scientific article published on 10 January 2014

Second generation analogs of rigid 6,7-spiro scaffolds targeting the bacterial ribosome

scientific article published on 08 October 2010

Streamlined Symmetrical Total Synthesis of Disorazole B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues

scientific article published on 27 August 2020

Structure-guided discovery of novel aminoglycoside mimetics as antibacterial translation inhibitors

scientific article

Synthesis and Biological Activity of Sarcodictyins

scientific article published on 01 June 1998

Synthesis and Biopharmaceutical Evaluation of Imatinib Analogues Featuring Unusual Structural Motifs.

scientific article published on 20 November 2015

Synthesis and characterization of novel natural product-Gd(III) MRI contrast agent conjugates

scientific article

Synthesis of 5,6-spiroethers and evaluation of their affinities for the bacterial A site.

scientific article published on 6 May 2011

Synthesis of dehydroalanine fragments as thiostrepton side chain mimetics

scientific article published in May 2005

Synthesis of triazole-functionalized 2-DOS analogues and their evaluation as A-site binders.

scientific article published on 9 January 2014

The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

scholarly article by K. C. Nicolaou et al published 3 January 2000 in Angewandte Chemie

Total Synthesis and Biological Evaluation of Natural and Designed Tubulysins.

scientific article published on February 2016

Total Synthesis of Epothilone A: The Olefin Metathesis Approach

article by Zhen Yang et al published 3 February 1997 in Angewandte Chemie International Edition

Total synthesis of apoptolidin: completion of the synthesis and analogue synthesis and evaluation.

scientific article published on December 2003

Unnatural rigid scaffolds targeting the bacterial ribosome

scientific article published on 01 August 2009

List of works by Dionisios Vourloumis

3,4-diaminobenzoic acid derivatives as inhibitors of the oxytocinase subfamily of M1 aminopeptidases with immune-regulating properties

A Homo sapiens cytoplasmic ribosomal decoding A-site affinity screen evaluating aminoglycoside and analogue binding ⬇️

A zebrafish in vivo phenotypic assay to identify 3-aminothiophene-2-carboxylic acid-based angiogenesis inhibitors

Aminoglycoside-hybrid ligands targeting the ribosomal decoding site

Chemical Biology of Epothilones

Cobalt-Assisted Claisen Rearrangement of Enediyne Lactones at Ambient Temperature. Studies toward a Synthetic Application of the Myers Cycloaromatization

Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.

Conformational dynamics of the EGFR kinase domain reveals structural features involved in activation.

Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency.

Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells

Designed spiro-bicyclic analogues targeting the ribosomal decoding center

Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes.

Discovery of potent vascular endothelial growth factor receptor-2 inhibitors

Exploration of zinc-binding groups for the design of inhibitors for the oxytocinase subfamily of M1 aminopeptidases

Heterometallic In(III)–Pd(II) Porous Metal–Organic Framework with Square-Octahedron Topology Displaying High CO2 Uptake and Selectivity toward CH4 and N2

Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody-Drug Conjugates.

Molecular recognition by glycoside pseudo base pairs and triples in an apramycin-RNA complex

Monitoring molecular recognition of the ribosomal decoding site

Novel 2,5-dideoxystreptamine derivatives targeting the ribosomal decoding site RNA.

Novel acyclic deoxystreptamine mimetics targeting the ribosomal decoding site

Novel copper(II) complex of N-propyl-norfloxacin and 1,10-phenanthroline with enhanced antileukemic and DNA nuclease activities

Novel paromamine derivatives exploring shallow-groove recognition of ribosomal-decoding-site RNA

Novel selective inhibitors of aminopeptidases that generate antigenic peptides.

Piperidine glycosides targeting the ribosomal decoding site.

Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides.

Rational design of azepane-glycoside antibiotics targeting the bacterial ribosome

Rigid spiroethers targeting the decoding center of the bacterial ribosome

Second generation analogs of rigid 6,7-spiro scaffolds targeting the bacterial ribosome

Streamlined Symmetrical Total Synthesis of Disorazole B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues

Structure-guided discovery of novel aminoglycoside mimetics as antibacterial translation inhibitors

Synthesis and Biological Activity of Sarcodictyins

Synthesis and Biopharmaceutical Evaluation of Imatinib Analogues Featuring Unusual Structural Motifs.

Synthesis and characterization of novel natural product-Gd(III) MRI contrast agent conjugates

Synthesis of 5,6-spiroethers and evaluation of their affinities for the bacterial A site.

Synthesis of dehydroalanine fragments as thiostrepton side chain mimetics

Synthesis of triazole-functionalized 2-DOS analogues and their evaluation as A-site binders.

The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

Total Synthesis and Biological Evaluation of Natural and Designed Tubulysins.

Total Synthesis of Epothilone A: The Olefin Metathesis Approach

Total synthesis of apoptolidin: completion of the synthesis and analogue synthesis and evaluation.

Unnatural rigid scaffolds targeting the bacterial ribosome