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List of works by Elaine Spooncer

A specific PTPRC/CD45 phosphorylation event governed by stem cell chemokine CXCL12 regulates primitive hematopoietic cell motility

scientific article published on September 2013

Aberrant expression of the multi-CSF gene in hematopoietic precursor and stem cell lines initiates leukemogenic progression.

scientific article published in January 1989

Abl protein kinase abrogates the response of multipotent haemopoietic cells to the growth inhibitor macrophage inflammatory protein-1 alpha ⬇️

scientific article published on March 12, 1998

Acquired cross-linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption.

scientific article published on 15 June 2017

Activation of granulocyte-macrophage colony-stimulating factor and interleukin-3 receptor subunits in a multipotential hematopoietic progenitor cell line leads to differential effects on development.

scientific article published on September 1999

An activated protein kinase C alpha gives a differentiation signal for hematopoietic progenitor cells and mimicks macrophage colony-stimulating factor-stimulated signaling events

scientific journal article

BCR-ABL alters the proliferation and differentiation response of multipotent hematopoietic cells to stem cell factor

scientific article published on May 2002

BCR/ABL modulates protein phosphorylation associated with the etoposide-induced DNA damage response

scientific article

Bcr-Abl protein tyrosine kinase activity induces a loss of p53 protein that mediates a delay in myeloid differentiation

scientific article

Biological consequences of p160v-abl protein tyrosine kinase activity in a primitive, multipotent haemopoietic cell line

scientific article published on April 1994

Biological effects of retroviral transfection of the murine interleukin-3 gene into FDCP-Mix cells

scientific article published on 01 January 1989

Cellular interactions between 3T3 cells and interleukin-3-dependent multipotent haemopoietic cells: a model system for stromal-cell-mediated haemopoiesis

scientific article published on May 1989

Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib.

scientific article published in October 2005

Comparative proteomics of primitive hematopoietic cell populations reveals differences in expression of proteins regulating motility

scientific article published on 05 February 2004

Continuous in vitro generation of multipotential stem cell clones from src-infected cultures

scientific article published on 01 July 1984

Correction: Identification of Nuclear Protein Targets for Six Leukemogenic Tyrosine Kinases Governed by Post-Translational Regulation.

scientific article published on 27 June 2013

Culturing Primitive Hemopoietic Cells : Long-Term Mouse Marrow Cultures and the Establishment of Factor-Dependent (FDCP-Mix) Hemopoietic Cell Lines

scientific article published on 01 January 1990

Culturing Primitive Hemopoietic Cells: Long-Term Mouse Marrow Cultures and the Establishment of Factor-Dependent (FDCP-Mix) Hemopoietic Cell Lines

scientific article published on January 1, 1997

Defective ability to self-renew in vitro of highly purified primitive haematopoietic cells

scientific article published in Nature

Developmental fate determination and marker discovery in hematopoietic stem cell biology using proteomic fingerprinting

scientific article

Differential effect of leukaemogenic tyrosine kinases on cell motility is governed by subcellular localisation.

scientific article published on May 2006

Ectopic interleukin-5 receptor expression promotes proliferation without development in a multipotent hematopoietic cell line

scientific article published on March 1998

Efficient retroviral-mediated gene transfer into human B lymphoblastoid cells expressing mouse ecotropic viral receptor ⬇️

scientific article published on October 11, 1992

Eight-channel iTRAQ enables comparison of the activity of six leukemogenic tyrosine kinases

scientific article published on 21 October 2007

Erythropoietic repopulating ability of stem cells from long-term marrow culture

scientific article published on 01 April 1987

Evaluation of a mouse Y chromosome probe for assessing marrow transplantation

scientific article published on 01 March 1989

Expression and downregulation of cytotoxic cell protease 1 or Granzyme 'B' transcripts during myeloid differentiation of interleukin-3-dependent murine stem cell lines

scientific article published in December 1992

Expression of the GM-CSF gene after retroviral transfer in hematopoietic stem cell lines induces synchronous granulocyte-macrophage differentiation

scientific article published on March 1991

Generation of a conditionally immortalized myeloid progenitor cell line requiring the presence of both interleukin-3 and stem cell factor to survive and proliferate

scientific article published on September 2003

Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia

scientific article

Growth and differentiation in the hemopoietic system

scientific article published on January 1987

Growth and differentiation of hematopoietic stem cells

scientific article published on January 1988

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

scientific article published on January 1990

Haemopoietic stem cells and the problem of self-renewal

scientific article published on 01 January 1984

Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis

scientific article published in Nature

Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation

scientific article

Infection of multipotent IL-3-dependent stem cells with a retroviral vector containing the IL-3 gene confers density-dependent growth autonomy without blocking differentiation

scientific article published in January 1989

Insertional mutagenesis as a route to identifying genes involved in self renewal of haemopoietic stem cells

scientific article published on 01 January 2000

Interleukin-3-dependent hematopoietic stem cell lines capable of osteoclast formation in vitro

scientific article published on September 1991

Interleukin-3-specific modification of cell membrane "fluidity" of haemopoietic cells

scientific article published on 01 January 1988

Isolation and characterization of polyfucosylated lactosaminoglycan from human granulocytes

scientific article published on 01 April 1984

Isolation of haemopoietic spleen colony forming cells

scientific article published on 01 January 1986

Long-term bone marrow cultures

scientific article published on 01 January 1984

Long-term in vitro correction of alpha-L-iduronidase deficiency (Hurler syndrome) in human bone marrow.

scientific article published on March 1996

Long-term marrow culture: an overview of techniques and experience.

scientific article published on January 1984

Loss of immunoreactivity in long-term bone marrow culture ⬇️

scientific article published on September 14, 1978

Lysophospholipids synergistically promote primitive hematopoietic cell chemotaxis via a mechanism involving Vav 1

scientific article published on 26 June 2003

Metabolically inactive 3T3 cells can substitute for marrow stromal cells to promote the proliferation and development of multipotent haemopoietic stem cells

scientific article published on August 1987

Mutants of a multipotent hematopoietic cell line blocked in GM-CSF-induced differentiation are leukemogenic in vivo.

scientific article published on August 1994

Nineteenth Paterson Symposium on “Haemopoietic Cell Growth Factors”

scientific article published in March 1985

Perturbed hemopoiesis and the generation of multipotential stem cell clones in src-infected bone marrow cultures is an indirect or transient effect of the oncogene

scientific article published on March 1986

Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells

scientific article published on 28 February 2006

Rates of mutation to growth factor autonomy and tumorigenicity differ in hematopoietic stem and precursor cells expressing the multilineage colony-stimulating factor gene

scientific article published on December 1989

Regulation of haemopoiesis in long-term bone marrow cultures. IV. Glycosaminoglycan synthesis and the stimulation of haemopoiesis by beta-D-xylosides

scientific article published on February 1983

Restriction of expression of an integrated recombinant retrovirus in primary but not immortalized murine hematopoietic stem cells

scientific article published on 01 June 1988

Retroviral Vectors Related to the Myeloproliferative Sarcoma Virus Allow Efficient Expression in Hematopoietic Stem and Precursor Cell Lines, but Retroviral Infection Is Reduced in More Primitive Cells ⬇️

scientific article published on January 1, 1991

Role of cytokines and extracellular matrix in the regulation of haemopoietic stem cells

scientific article published on 01 December 1998

Role of the cellular matrix in haemopoiesis. I. Synthesis of glycosaminoglycans by mouse bone marrow cell cultures

scientific article published on 01 September 1983

Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

scientific article published on January 1986

Self-renewal of haemopoietic stem cells: the roles of the environment, of growth factors and of the src oncogene.

scientific article

Stromal cells in haemopoiesis

scientific article

Structure of sialylated fucosyl lactosaminoglycan isolated from human granulocytes

scientific article published on 01 September 1984

Studies on the self-renewal and differentiation of stem cells in long term marrow cultures

scientific article published in January 1985

THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo

scientific journal article

Targeted in vivo infection with a retroviral vector carrying the interleukin-3 (multi-CSF) gene leads to immortalization and leukemic transformation of primitive hematopoietic progenitor cells

scientific article published on January 1993

The Hox-2.4 gene is not involved in the generation of IL-3 dependent multipotent FDCP-mix cell lines

scientific article published on January 1995

The kinetic response of haemopoietic precursor cells, in vivo, to highly purified, recombinant interleukin-3

scientific article published on 01 January 1986

The mouse M-lysozyme gene domain: identification of myeloid and differentiation specific DNasel hypersensitive sites and of a 3'-cis acting regulatory element

scientific article

The regulation of hemopoietic cell development by the stromal cell environment and diffusible regulatory molecules.

scientific article published on January 1984

The rho-kinase inhibitors Y-27632 and fasudil act synergistically with imatinib to inhibit the expansion of ex vivo CD34(+) CML progenitor cells.

scientific article published on 7 June 2007

The role of cells and their products in the regulation of in vitro stem cell proliferation and granulocyte development ⬇️

scientific article published on 01 January 1980

The role of growth factors in self-renewal and differentiation of haemopoietic stem cells

scientific article published on March 1990

The role of stromal cells and growth factors in haemopoiesis and modulation of their effects by the src oncogene

scientific article

The specific enhancement of interferon alpha induced growth inhibition by BCR/ABL only occurs in multipotent cells

scientific article published on January 2001

Towards gene therapy of Hurler syndrome

scientific article

Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells

scientific article published on December 2000

Transplantation of Cultured Hemopoietic Stem Cells ⬇️

scientific article published on 01 January 1980

Transplantation of long-term cultured bone marrow cells

scientific article published on 01 June 1983

p210 Bcr-Abl expression in a primitive multipotent haematopoietic cell line models the development of chronic myeloid leukaemia.

scientific article published on August 1998

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