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List of works by Kaarina Sivonen

4-Methylproline guided natural product discovery: co-occurrence of 4-hydroxy- and 4-methylprolines in nostoweipeptins and nostopeptolides.

scientific article

A Novel Cyanobacterial Nostocyclopeptide is a Potent Antitoxin against Microcystins

scientific article published on 23 June 2010

A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway

scientific article published on 05 February 2016

A high proportion of Baltic Sea benthic cyanobacterial isolates contain apoptogens able to induce rapid death of isolated rat hepatocytes.

scientific article

A liquid chromatography–mass spectrometric method for the detection of cyclic β-amino fatty acid lipopeptides

scientific article published on 15 February 2016

Acyloxymethyl esterification of nodularin-R and microcystin-LA produces inactive protoxins that become reactivated and produce apoptosis inside intact cells

scientific article published in September 2009

Allelopathy of Baltic Sea cyanobacteria: no evidence for the role of nodularin

article

Alternative Biosynthetic Starter Units Enhance the Structural Diversity of Cyanobacterial Lipopeptides

scientific article published on 06 February 2019

Anabaenolysins, novel cytolytic lipopeptides from benthic Anabaena cyanobacteria

scientific article

Analysis of an inactive cyanobactin biosynthetic gene cluster leads to discovery of new natural products from strains of the genus Microcystis

scientific article

Analytical Methods Workgroup report

scientific article published on 01 January 2008

Anatoxin-a producing Tychonema (Cyanobacteria) in European waterbodies

scientific article published on 18 November 2014

Anatoxin-a synthetase gene cluster of the cyanobacterium Anabaena sp. strain 37 and molecular methods to detect potential producers

scientific article

Antifungal activity improved by coproduction of cyclodextrins and anabaenolysins in Cyanobacteria

scientific article

Antifungal compounds from cyanobacteria.

scientific article

Antitumor astins originate from the fungal endophyte Cyanodermella asteris living within the medicinal plant Aster tataricus

scientific article published on 06 December 2019

Associations of cyanobacterial toxin, nodularin, with environmental factors and zooplankton in the Baltic Sea.

scientific article published on 23 December 2003

Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes.

scientific article

BASIC: Baltic Sea cyanobacteria. An investigation of the structure and dynamics of water blooms of cyanobacteria in the Baltic Sea—responses to a changing environment

article

Bacteria contribute to sediment nutrient release and reflect progressed eutrophication-driven hypoxia in an organic-rich continental sea

scientific article

Bacterial diversity and function in the Baltic Sea with an emphasis on cyanobacteria.

scientific article

Benthic cyanobacteria from the Baltic Sea contain cytotoxic Anabaena, Nodularia, and Nostoc strains and an apoptosis-inducing Phormidium strain.

scientific article

Benthic cyanobacteria of the genus Nodularia are non-toxic, without gas vacuoles, able to glide and genetically more diverse than planktonic Nodularia

scientific article

Biosynthesis of microcystin hepatotoxins in the cyanobacterial genus Fischerella.

scientific article

Biosynthesis of the Bis-Prenylated Alkaloids Muscoride A and B

scientific article published on 19 November 2019

CORRESPONDENCE BETWEEN PHYLOGENY AND MORPHOLOGY OF SNOWELLA SPP. AND WORONICHINIA NAEGELIANA, CYANOBACTERIA COMMONLY OCCURRING IN LAKES1

article

Calanoid copepods feed and produce eggs in the presence of toxic cyanobacteriaNodularia spumigena

article

Characterization of ten H2 producing cyanobacteria isolated from the Baltic Sea and Finnish lakes

article

Characterization of the interaction of the antifungal and cytotoxic cyclic glycolipopeptide hassallidin with sterol-containing lipid membranes

scientific article published on 19 June 2019

Chemical diversity and cellular effects of antifungal cyclic lipopeptides from cyanobacteria

Comparative Genomics of the Baltic Sea Toxic Cyanobacteria Nodularia spumigena UHCC 0039 and Its Response to Varying Salinity.

scientific article published on 8 March 2018

Competition between a toxic and a non-toxic Microcystis strain under constant and pulsed nitrogen and phosphorus supply

article

Convergent evolution of [D-Leucine(1)] microcystin-LR in taxonomically disparate cyanobacteria

scientific article

Coupling biogeochemical process rates and metagenomic blueprints of coastal bacterial assemblages in the context of environmental change

scientific article published on 01 August 2018

Culture-independent evidence for the persistent presence and genetic diversity of microcystin-producing Anabaena (Cyanobacteria) in the Gulf of Finland

scientific article

CyanoMetDB, a comprehensive public database of secondary metabolites from cyanobacteria

scientific article

Cyanobacteria as a Source for Novel Anti-Leukemic Compounds

scientific article published on 26 August 2015

Cyanobacteria from terrestrial and marine sources contain apoptogens able to overcome chemoresistance in acute myeloid leukemia cells.

scientific article published on 3 April 2014

Cyanobacteria produce a high variety of hepatotoxic peptides in lichen symbiosis

scientific article published on 26 March 2012

Cyanobacterial Toxic and Bioactive Peptides in Freshwater Bodies of Greece: Concentrations, Occurrence Patterns, and Implications for Human Health

scientific article

Cyanobactins-ribosomal cyclic peptides produced by cyanobacteria

scientific article published on 27 February 2010

Cyanodermella asteris sp. nov. (Ostropales) from the inflorescence axis of Aster tataricus

scientific article published in 2017

Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants.

scientific article published on 14 September 2017

Dereplication of Natural Products with Antimicrobial and Anticancer Activity from Brazilian Cyanobacteria

scientific article published on 24 December 2019

Detection of microcystin-producing cyanobacteria in Finnish lakes with genus-specific microcystin synthetase gene E (mcyE) PCR and associations with environmental factors

scientific article published on September 2006

Development of a chip assay and quantitative PCR for detecting microcystin synthetase E gene expression

scientific article published on 16 April 2010

Development of a universal microarray based on the ligation detection reaction and 16S rrna gene polymorphism to target diversity of cyanobacteria

scientific article published on December 2004

Direct evidence for production of microcystins by Anabaena strains from the Baltic Sea

scientific article

Discovering protein kinase C active plants growing in Finland utilizing automated bioassay combined to LC/MS.

scientific article

Discovery of a pederin family compound in a non-symbiotic bloom-forming cyanobacterium.

scientific article published on 23 March 2018

Discovery of rare and highly toxic microcystins from lichen-associated cyanobacterium Nostoc sp. strain IO-102-I

scientific article published on October 2004

Discovery of varlaxins, new aeruginosin-type inhibitors of human trypsins

scientific article published on 9 March 2022

Diversity of Aphanizomenon flos-aquae (cyanobacterium) populations along a Baltic Sea salinity gradient.

scientific article published on November 2002

Diversity of hepatotoxic microcystins and bioactive anabaenopeptins in cyanobacterial blooms from Greek freshwaters

scientific article published in 2005

Draft genome sequence of Talaromyces islandicus ("Penicillium islandicum") WF-38-12, a neglected mold with significant biotechnological potential

scientific article published on 18 July 2015

Draft genome sequence of calothrix strain 336/3, a novel h2-producing cyanobacterium isolated from a finnish lake

scientific article

Effect of Nutrient Loading on Bacterioplankton Community Composition in Lake Mesocosms

article

Effect of humic material on the bacterioplankton community composition in boreal lakes and mesocosms.

scientific article

Effect of nitrogen and phosphorus on growth of toxic and nontoxic Microcystis strains and on intracellular microcystin concentrations

scientific article published on 15 April 2002

Effect of nutrient enrichment on bacterioplankton biomass and community composition in mesocosms in the Archipelago Sea, northern Baltic

article

Effects of allochthonous dissolved organic matter input on microbial composition and nitrogen-cycling genes at two contrasting estuarine sites

scientific article published on 01 September 2019

Effects of phosphate and light on growth of and bioactive peptide production by the Cyanobacterium anabaena strain 90 and its anabaenopeptilide mutant.

scientific article

Emerging high throughput analyses of cyanobacterial toxins and toxic cyanobacteria

scientific article

Endotoxins associated with cyanobacteria and their removal during drinking water treatment

scientific article published in May 2002

Evidence for positive selection acting on microcystin synthetase adenylation domains in three cyanobacterial genera

scientific article

Evolving interactions between diazotrophic cyanobacterium and phage mediate nitrogen release and host competitive ability

scientific article

Expression of the nodularin synthetase genes in the Baltic Sea bloom-former cyanobacterium Nodularia spumigena strain AV1.

scientific article published on 22 May 2008

Extended H2 photoproduction by N2-fixing cyanobacteria immobilized in thin alginate films

Fatty Acid Substitutions Modulate the Cytotoxicity of Puwainaphycins/Minutissamides Isolated from the Baltic Sea Cyanobacterium Nodularia harveyana UHCC-0300

First report of the cyanobacterium Aphanizomenon ovalisporum Forti in two Greek lakes and cyanotoxin occurrence

scientific article published in December 2005

Frequency of virus-resistant hosts determines experimental community dynamics

scientific article published on 28 November 2018

Genes coding for hepatotoxic heptapeptides (microcystins) in the cyanobacterium Anabaena strain 90

scientific article

Genetic Organization of Anabaenopeptin and Spumigin Biosynthetic Gene Clusters in the Cyanobacterium Sphaerospermopsis torques-reginae ITEP-024.

scientific article published on 13 January 2017

Genetic diversity in strains of the genus Anabaena isolated from planktonic and benthic habitats of the Gulf of Finland (Baltic Sea).

scientific article published on 10 March 2008

Genome Reduction and Secondary Metabolism of the Marine Sponge-Associated Cyanobacterium

Genome mining demonstrates the widespread occurrence of gene clusters encoding bacteriocins in cyanobacteria

scientific article

Genome mining expands the chemical diversity of the cyanobactin family to include highly modified linear peptides

scientific article published in August 2013

Genome-derived insights into the biology of the hepatotoxic bloom-forming cyanobacterium Anabaena sp. strain 90

scientific article

Genomic insights into the distribution, genetic diversity and evolution of polyketide synthases and nonribosomal peptide synthetases

scientific article

Guest editorial

scholarly article by Kaarina Sivonen published 2005 in Environmental Toxicology

Hassallidins, antifungal glycolipopeptides, are widespread among cyanobacteria and are the end-product of a nonribosomal pathway

scientific article

High diversity of cultivable heterotrophic bacteria in association with cyanobacterial water blooms

scientific article

High-Quality Draft Genome Sequence of Pantanalinema sp. GBBB05, a Cyanobacterium From Cerrado Biome

scientific article published in 2021

Highly diverse cyanobactins in strains of the genus Anabaena.

scientific article published on 11 December 2009

Hydrogen photoproduction by immobilized n2-fixing cyanobacteria: understanding the role of the uptake hydrogenase in the long-term process

scientific article published on 11 July 2014

Hydrophobic derivatives of 5-(hydroxymethyl)isophthalic acid that selectively induce apoptosis in leukemia cells but not in fibroblasts

Identification of geosmin and 2-methylisoborneol in cyanobacteria and molecular detection methods for the producers of these compounds.

scientific article published on January 2015

Identification of hepatotoxin-producing cyanobacteria by DNA-chip

scientific article published on 7 January 2008

Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing

scientific article

Insight into the genome and brackish water adaptation strategies of toxic and bloom-forming Baltic Sea Dolichospermum sp. UHCC 0315

article

Insights into the physiology and ecology of the brackish-water-adapted Cyanobacterium Nodularia spumigena CCY9414 based on a genome-transcriptome analysis

scientific article

Interlaboratory comparison of Taq Nuclease Assays for the quantification of the toxic cyanobacteria Microcystis sp.

scientific article published on 19 December 2006

Lichen species identity and diversity of cyanobacterial toxins in symbiosis

scientific article published on March 6, 2013

Limnothrix redekei (Van Goor) Meffert (Cyanobacteria) Strains from Lake Kastoria, Greece Form a Separate Phylogenetic Group

scientific article published in January 2005

Lipid biomarker signatures as tracers for harmful cyanobacterial blooms in the Baltic Sea.

scientific article

Marine benthic cyanobacteria contain apoptosis-inducing activity synergizing with daunorubicin to kill leukemia cells, but not cardiomyocytes

scientific article published on 14 October 2010

Microcystin Production in the Tripartite Cyanolichen Peltigera leucophlebia

article

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

Mining of Cyanobacterial Genomes Indicates Natural Product Biosynthetic Gene Clusters Located in Conjugative Plasmids

scientific article published on 04 November 2021

Molecular methods: chip assay and quantitative real-time PCR: in detecting hepatotoxic cyanobacteria

scientific article published in January 2011

N-Prenylation of Tryptophan by an Aromatic Prenyltransferase from the Cyanobactin Biosynthetic Pathway

scientific article published on 03 December 2018

Natural Product Biosynthetic Diversity and Comparative Genomics of the Cyanobacteria

scientific article published on October 2015

Natural occurrence of microcystin synthetase deletion mutants capable of producing microcystins in strains of the genus Anabaena (Cyanobacteria).

scientific article published in April 2008

New structural variants of aeruginosin produced by the toxic bloom forming cyanobacterium Nodularia spumigena

scientific article (publication date: 2013)

Newly isolated Nodularia phage influences cyanobacterial community dynamics

scientific article

Nodularia spumigena extract induces upregulation of mitochondrial respiratory chain complexes in spinach (Spinacia oleracea L.)

article published in 2012

Nodularin uptake and induction of oxidative stress in spinach (Spinachia oleracea)

article by Nina Lehtimäki et al published April 2011 in The Journal of Plant Physiology

Non-autonomous transposable elements associated with inactivation of microcystin gene clusters in strains of the genus Anabaena isolated from the Baltic Sea

article

Nostocyclopeptide-M1: a potent, nontoxic inhibitor of the hepatocyte drug transporters OATP1B3 and OATP1B1.

scientific article published on 24 January 2011

Nostophycin biosynthesis is directed by a hybrid polyketide synthase-nonribosomal peptide synthetase in the toxic cyanobacterium Nostoc sp. strain 152.

scientific article published on 23 September 2011

Nostophycin, a Novel Cyclic Peptide from the Toxic CyanobacteriumNostocsp. 152

scientific article published on 26 July 2002

Nostosins, Trypsin Inhibitors Isolated from the Terrestrial Cyanobacterium Nostoc sp. Strain FSN

scientific article published on 01 August 2014

PCR-based identification of microcystin-producing genotypes of different cyanobacterial genera.

scientific article published on 10 October 2003

Pathologic findings and toxin identification in cyanobacterial (Nodularia spumigena) intoxication in a dog.

scientific article published on 8 August 2011

Phosphorus chemistry and bacterial community composition interact in brackish sediments receiving agricultural discharges

scientific article

Phosphorus limitation and diel control of nitrogen-fixing cyanobacteria in the Baltic Sea

article

Phylogenetic and morphological evaluation of the genera Anabaena, Aphanizomenon, Trichormus and Nostoc (Nostocales, Cyanobacteria).

scientific article

Phylogenetic comparison of the cyanobacterial genera Anabaena and Aphanizomenon

scientific article published in September 2002

Phylogenetic evidence for the early evolution of microcystin synthesis

scientific article (publication date: 13 January 2004)

Phylogenomic Analysis of Secondary Metabolism in the Toxic Cyanobacterial Genera Anabaena, Dolichospermum and Aphanizomenon

scientific article published on 11 April 2020

Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria.

scientific article

Post-Translational Tyrosine Geranylation in Cyanobactin Biosynthesis.

scientific article published on 27 April 2018

Potent Inhibitor of Human Trypsins from the Aeruginosin Family of Natural Products

scientific article

Production of High Amounts of Hepatotoxin Nodularin and New Protease Inhibitors Pseudospumigins by the Brazilian Benthic Nostoc sp. CENA543.

scientific article published on 9 October 2017

Pseudoaeruginosins, nonribosomal peptides in Nodularia spumigena

scientific article

Quantitative real-time PCR detection of toxic Nodularia cyanobacteria in the Baltic Sea

scientific article published on 2 February 2007

Quantitative real-time PCR for determination of microcystin synthetase e copy numbers for microcystis and anabaena in lakes.

scientific article

Rearranged Biosynthetic Gene Cluster and Synthesis of Hassallidin E in Planktothrix serta PCC 8927.

scientific article

Recurrent adenylation domain replacement in the microcystin synthetase gene cluster.

scientific article

Repeat-type distribution in trnL intron does not correspond with species phylogeny: comparison of the genetic markers 16S rRNA and trnL intron in heterocystous cyanobacteria.

scientific article

Reply to Sasso et al.: Distribution and phylogeny of nonribosomal peptide and polyketide biosynthetic pathways in eukaryotes

scientific article

Responses of Baltic Sea ice and open-water natural bacterial communities to salinity change

scientific article

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

scientific article

Screening for biohydrogen production by cyanobacteria isolated from the Baltic Sea and Finnish lakes

article

Screening native isolates of cyanobacteria and a green alga for integrated wastewater treatment, biomass accumulation and neutral lipid production

article

Secondary metabolite from Nostoc XPORK14A inhibits photosynthesis and growth of Synechocystis PCC 6803.

scientific article published in June 2014

Shared PKS Module in Biosynthesis of Synergistic Laxaphycins

scientific article published on 16 September 2020

Shared PKS modules in biosynthesis of synergistic laxaphycins

Simultaneous Production of Anabaenopeptins and Namalides by the Cyanobacterium Nostoc sp. CENA543.

scientific article published on 21 September 2017

Sphaerocyclamide, a prenylated cyanobactin from the cyanobacterium Sphaerospermopsis sp. LEGE 00249

scientific article published in Scientific Reports

Strains of the cyanobacterial genera Calothrix and Rivularia isolated from the Baltic Sea display cryptic diversity and are distantly related to Gloeotrichia and Tolypothrix.

scientific article published on 27 April 2007

Strains of the toxic and bloom-forming Nodularia spumigena (cyanobacteria) can degrade methylphosphonate and release methane.

scientific article

Structures of three new cyclic heptapeptide hepatotoxins produced by the cyanobacterium (blue-green alga) Nostoc sp. strain 152

scientific article published on 18 March 2005

The Biosynthesis of Rare Homo-Amino Acid Containing Variants of Microcystin by a Benthic Cyanobacterium.

scientific article published on 7 May 2019

The cyclochlorotine mycotoxin is produced by the nonribosomal peptide synthetase CctN in Talaromyces islandicus ('Penicillium islandicum').

scientific article

The genetic basis for O-acetylation of the microcystin toxin in cyanobacteria.

scientific article published in July 2013

The lipopeptide toxins anabaenolysin A and B target biological membranes in a cholesterol-dependent manner.

scientific article

The non-ribosomal assembly and frequent occurrence of the protease inhibitors spumigins in the bloom-forming cyanobacterium Nodularia spumigena

scientific article published on 19 August 2009

The presence of microcystins and other cyanobacterial bioactive peptides in aquatic fauna collected from Greek freshwaters

scientific article published in June 2006

The structure and biosynthesis of heinamides A1–A3 and B1–B5, antifungal members of the laxaphycin lipopeptide family

scientific article

The swinholide biosynthetic gene cluster from a terrestrial cyanobacterium Nostoc sp. UHCC 0450.

scientific article published on 17 November 2017

Transcriptomic and Proteomic Profiling of Anabaena sp. Strain 90 under Inorganic Phosphorus Stress

scientific article published on 29 May 2015

Trophic transfer of cyanobacterial toxins from zooplankton to planktivores: Consequences for pike larvae and mysid shrimps

scientific article published on 01 June 2005

Two alternative starter modules for the non-ribosomal biosynthesis of specific anabaenopeptin variants in Anabaena (Cyanobacteria).

scientific article

Virulence genes of Aeromonas isolates, bacterial endotoxins and cyanobacterial toxins from recreational water samples associated with human health symptoms.

scientific article published on December 2011

Widespread occurrence and lateral transfer of the cyanobactin biosynthesis gene cluster in cyanobacteria

scientific article