Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Irma Thesleff

A missense mutation in PAX9 in a family with distinct phenotype of oligodontia

scientific article (publication date: November 2003)

Affecting tooth morphology and renewal by fine-tuning the signals mediating cell and tissue interactions

scientific article published on January 2007

An integrated gene regulatory network controls stem cell proliferation in teeth

scientific article published in June 2007

Bono1: a gene associated with regions of deposition of bone and dentine

scientific article

Chondrogenic potential of mouse calvarial mesenchyme

scientific article published on 01 May 2005

Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling

scientific article

Continuous tooth replacement: the possible involvement of epithelial stem cells

scientific article published in June 2004

Cooperation of Nectin-1 and Nectin-3 Is Required for Maintenance of Epidermal Stratification and Proper Hair Shaft Formation in the Mouse

Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth

scientific article published on October 1, 2010

Death receptor signaling giving life to ectodermal organs

scientific article

Delayed tooth movement in Runx2+/- mice associated with mTORC2 in stretch-induced bone formation

scientific article published on 27 May 2020

Development of ectodermal organs

scientific article published in January 2014

Developmental biology and building a tooth

scientific article published on September 1, 2003

Developmental toxicity of dioxin to mouse embryonic teeth in vitro: arrest of tooth morphogenesis involves stimulation of apoptotic program in the dental epithelium

scientific article

Different roles of Runx2 during early neural crest-derived bone and tooth development

scientific article published on July 2006

Directional cell migration, but not proliferation, drives hair placode morphogenesis

scientific article published in March 2014

Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate

scientific journal article

Early epithelial signaling center governs tooth budding morphogenesis

scientific article

Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages

scientific article published on 15 September 2004

Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis

scientific article published in July 2011

Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression

scientific article published in January 2007

Ectodysplasin regulates activator-inhibitor balance in murine tooth development through Fgf20 signaling

scientific article

Ectodysplasin signaling in development

scientific article

Ectodysplasin, Edar and TNFRSF19 are expressed in complementary and overlapping patterns during mouse embryogenesis.

scientific article published in October 2003

Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development

scientific journal article

Effect of Estrogen and Food Hardness on Metabolism and Turnover of Condylar Cartilage

scientific article published in January 2015

Epithelial-mesenchymal signalling regulating tooth morphogenesis

scientific article

Explant Cultures of Embryonic Epithelium: Analysis of Mesenchymal Signals

article

Explant culture of embryonic craniofacial tissues: analyzing effects of signaling molecules on gene expression

scientific article published on 01 January 2010

Expression of Foxi3 is regulated by ectodysplasin in skin appendage placodes

scientific article published on 9 April 2013

Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone development

scientific article published on 01 November 2002

Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone development

scientific article published on 01 December 2002

Expression of the novel Golgi protein GoPro49 is developmentally regulated during mesenchymal differentiation

scientific article

Expression of the stem cell marker, SOX2, in ameloblastoma and dental epithelium

scientific article published on October 23, 2013

Fgfr2b mediated epithelial-mesenchymal interactions coordinate tooth morphogenesis and dental trigeminal axon patterning

scientific journal article

Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation

scientific journal article

Foxc1 integrates Fgf and Bmp signalling independently of twist or noggin during calvarial bone development

scientific article published in July 2005

From understanding tooth development to bioengineering of teeth

article

Functionally Distinctive Ptch Receptors Establish Multimodal Hedgehog Signaling in the Tooth Epithelial Stem Cell Niche

scientific article published on 10 June 2019

Glial origin of mesenchymal stem cells in a tooth model system

scientific article published on 27 July 2014

Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot

scientific article (publication date: December 2003)

Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes

scientific journal article

Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth

scientific article

Initiation of teeth from the dental lamina in the ferret

scientific article published on 6 January 2014

Introduction to the ECR special odontology issue

scientific article published on 18 April 2014

List of Contributors

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth

scientific article published in August 2002

Mechanisms of ectodermal organogenesis

scientific article published on October 15, 2003

Mesenchymal Wnt/β-Catenin Signaling Controls Epithelial Stem Cell Homeostasis in Teeth by Inhibiting the Antiapoptotic Effect of Fgf10.

scientific article published in May 2015

Mesenchymal Wnt/β-catenin signaling limits tooth number.

scientific article published on 2 February 2018

Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth

scientific journal article

Molecular mechanisms in calvarial bone and suture development, and their relation to craniosynostosis

scientific article published on April 1, 2003

Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer

scientific article

Nonindependence of mammalian dental characters

scientific article published in November 2004

Notch signalling is required for the survival of epithelial stem cells in the continuously growing mouse incisor

scientific article published on August 6, 2010

Novel strategies for expansion of tooth epithelial stem cells and ameloblast generation

scientific article published on 18 March 2020

Observations on continuously growing roots of the sloth and the K14-Eda transgenic mice indicate that epithelial stem cells can give rise to both the ameloblast and root epithelium cell lineage creating distinct tooth patterns

scientific article

Organ culture in the analysis of tissue interactions

scientific article published on 01 January 2008

Pathogenesis of ectodermal dysplasia.

scientific article published on 25 May 2012

Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells

scientific article published in January 2010

Phenotypic changes in dentition of Runx2 homozygote-null mutant mice

scientific journal article

Possible roles of Runx1 and Sox9 in incipient intramembranous ossification

scientific article

Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4

scientific article published on October 1, 2003

Regulation of Twist, Snail, and Id1 is conserved between the developing murine palate and tooth

scientific article published in September 2005

Regulation of epithelial stem cells in tooth regeneration

scientific article published on 9 May 2007

Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar

scientific journal article

Regulation of mammalian tooth cusp patterning by ectodin

scientific journal article

Runx1 is involved in the fusion of the primary and the secondary palatal shelves.

scientific article published on 29 October 2008

Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis

scientific journal article

Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity

scientific article published on 17 April 2003

Signaling Networks Regulating Tooth Organogenesis and Regeneration, and the Specification of Dental Mesenchymal and Epithelial Cell Lineages

scientific article published on April 1, 2012

Sostdc1 defines the size and number of skin appendage placodes

scientific article published on April 15, 2012

Sox2 marks epithelial competence to generate teeth in mammals and reptiles

scientific article published on 5 March 2013

Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors

scientific article published on 19 July 2012

Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ

scientific article published on 30 June 2020

Splitting placodes: effects of bone morphogenetic protein and Activin on the patterning and identity of mouse incisors

scientific article published on July 2010

Stem Cells and Tissue Engineering: Prospects for Regenerating Tissues in Dental Practice

scientific article published on January 1, 2003

Stimulation of ectodermal organ development by Ectodysplasin-A1.

scientific article published in July 2003

Sumo-1 function is dispensable in normal mouse development

scientific article published on 23 June 2008

Suppression of epithelial differentiation by Foxi3 is essential for molar crown patterning

scientific article published on 8 October 2015

Sustained epithelial beta-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation

scientific article published on 6 February 2008

The genetic basis of tooth development and dental defects

scientific article published in December 2006

The importance of signal pathway modulation in all aspects of tooth development

scientific article published in June 2009

The role of growth factors in tooth development

scientific article

The role of the dental lamina in mammalian tooth replacement

scientific article published in June 2009

The taming of the shrew milk teeth

scientific article published in July 2008

The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics

scientific article

Tinkering with the inductive mesenchyme: Sostdc1 uncovers the role of dental mesenchyme in limiting tooth induction

scientific article published in February 2009

Tissue Interactions Regulating Tooth Development and Renewal

scientific article published on 06 October 2015

Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs

scientific journal article

Tooth organogenesis and regeneration

scientific article published on 9 July 2010

Tooth patterning and enamel formation can be manipulated by misexpression of TNF receptor Edar

scientific article published in October 2004

Tooth shape formation and tooth renewal: evolving with the same signals

scientific article published on October 1, 2012

Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4

scientific article

Wnt10a regulates dentin sialophosphoprotein mRNA expression and possibly links odontoblast differentiation and tooth morphogenesis

scientific journal article

p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation

scientific journal article