List of works - Gert C Scheper

A human pathology-related mutation prevents import of an aminoacyl-tRNA synthetase into mitochondria

scientific article published on February 2011

A yeast purification system for human translation initiation factors eIF2 and eIF2Bε and their use in the diagnosis of CACH/VWM disease

scientific article

Adenovirus vector-based prime-boost vaccination via heterologous routes induces cervicovaginal CD8+ T cell responses against HPV16 oncoproteins

scientific article published on 21 November 2017

Analysis of CLCN2 as candidate gene for megalencephalic leukoencephalopathy with subcortical cysts

scientific article published in April 2010

Astrocytes are central in the pathomechanisms of vanishing white matter

scientific article

Correspondence on "Spinal cord calcification in an early-onset progressive leukoencephalopathy"

scientific article published on 01 August 2011

Defective glial maturation in vanishing white matter disease.

scientific article

Defective translation initiation causes vanishing of cerebral white matter

scientific article

Development of a replication-deficient adenoviral vector-based vaccine candidate for the interception of HPV16- and HPV18-induced infections and disease

scientific article published on 6 March 2017

Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?

scientific article

Features in the N and C termini of the MAPK-interacting kinase Mnk1 mediate its nucleocytoplasmic shuttling

scientific article published on 28 August 2003

Knockdown of MLC1 in primary astrocytes causes cell vacuolation: A MLC disease cell model ⬇️

scientific article published on April 3, 2011

Leukoencephalopathy With Vanishing White Matter: A Review ⬇️

scientific article published on October 1, 2010

Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation is associated with cell-type-dependent splicing of mtAspRS mRNA ⬇️

scientific article published on February 1, 2012

Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation: clinical and genetic characterization and target for therapy

scientific article

Leukoencephalopathy with brainstem and spinal cord involvement and normal lactate: a new mutation in the DARS2 gene

scientific article published on 25 May 2010

Localisation and regulation of the eIF4E-binding protein 4E-BP3.

scientific article

MLC1 is associated with the dystrophin-glycoprotein complex at astrocytic endfeet

scientific article

MLC1: a novel protein in distal astroglial processes

scientific article

MRI of a family with leukoencephalypathy with vanishing white matter.

scientific article published on 24 May 2005

Megalencephalic leucoencephalopathy with cysts: defect in chloride currents and cell volume regulation.

scientific article

Megalencephalic leukoencephalopathy with subcortical cysts: an update and extended mutation analysis of MLC1.

scientific article

Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle

scientific article published on 4 December 2014

Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation

scientific article

Molecular pathogenesis of megalencephalic leukoencephalopathy with subcortical cysts: mutations in MLC1 cause folding defects

scientific article

Mutant GlialCAM causes megalencephalic leukoencephalopathy with subcortical cysts, benign familial macrocephaly, and macrocephaly with retardation and autism

scientific article

Pathogenic mutations causing LBSL affect mitochondrial aspartyl-tRNA synthetase in diverse ways ⬇️

scientific article published on March 1, 2013

Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA.

scientific article

Regulation of protein synthesis in lymphoblasts from vanishing white matter patients

scientific article

Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes.

scientific article published in September 2011

The Drosophila protein kinase LK6 is regulated by ERK and phosphorylates the eukaryotic initiation factor eIF4E in vivo

scientific article

The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization

scientific article

Translation matters: protein synthesis defects in inherited disease

scientific article (publication date: September 2007)

Two cases with megalencephalic leukoencephalopathy with subcortical cysts and MLC1 mutations in the Turkish population

scientific article

Vanishing white matter disease

scientific article

Vanishing white matter disease associated with ptosis and myoclonic seizures

scientific article

Vanishing white matter disease: a review with focus on its genetics

scientific article

Vanishing white matter disease: the first reported chinese patient

scientific article

eIF2B-related disorders: antenatal onset and involvement of multiple organs

scientific article

List of works by Gert C Scheper

A human pathology-related mutation prevents import of an aminoacyl-tRNA synthetase into mitochondria

A yeast purification system for human translation initiation factors eIF2 and eIF2Bε and their use in the diagnosis of CACH/VWM disease

Adenovirus vector-based prime-boost vaccination via heterologous routes induces cervicovaginal CD8+ T cell responses against HPV16 oncoproteins

Analysis of CLCN2 as candidate gene for megalencephalic leukoencephalopathy with subcortical cysts

Astrocytes are central in the pathomechanisms of vanishing white matter

Correspondence on "Spinal cord calcification in an early-onset progressive leukoencephalopathy"

Defective glial maturation in vanishing white matter disease.

Defective translation initiation causes vanishing of cerebral white matter

Development of a replication-deficient adenoviral vector-based vaccine candidate for the interception of HPV16- and HPV18-induced infections and disease

Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?

Features in the N and C termini of the MAPK-interacting kinase Mnk1 mediate its nucleocytoplasmic shuttling

Knockdown of MLC1 in primary astrocytes causes cell vacuolation: A MLC disease cell model ⬇️

Leukoencephalopathy With Vanishing White Matter: A Review ⬇️

Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation is associated with cell-type-dependent splicing of mtAspRS mRNA ⬇️

Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation: clinical and genetic characterization and target for therapy

Leukoencephalopathy with brainstem and spinal cord involvement and normal lactate: a new mutation in the DARS2 gene

Localisation and regulation of the eIF4E-binding protein 4E-BP3.

MLC1 is associated with the dystrophin-glycoprotein complex at astrocytic endfeet

MLC1: a novel protein in distal astroglial processes

MRI of a family with leukoencephalypathy with vanishing white matter.

Megalencephalic leucoencephalopathy with cysts: defect in chloride currents and cell volume regulation.

Megalencephalic leukoencephalopathy with subcortical cysts: an update and extended mutation analysis of MLC1.

Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle

Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation

Molecular pathogenesis of megalencephalic leukoencephalopathy with subcortical cysts: mutations in MLC1 cause folding defects

Mutant GlialCAM causes megalencephalic leukoencephalopathy with subcortical cysts, benign familial macrocephaly, and macrocephaly with retardation and autism

Pathogenic mutations causing LBSL affect mitochondrial aspartyl-tRNA synthetase in diverse ways ⬇️

Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA.

Regulation of protein synthesis in lymphoblasts from vanishing white matter patients

Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes.

The Drosophila protein kinase LK6 is regulated by ERK and phosphorylates the eukaryotic initiation factor eIF4E in vivo

The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization

Translation matters: protein synthesis defects in inherited disease

Two cases with megalencephalic leukoencephalopathy with subcortical cysts and MLC1 mutations in the Turkish population

Vanishing white matter disease

Vanishing white matter disease associated with ptosis and myoclonic seizures

Vanishing white matter disease: a review with focus on its genetics

Vanishing white matter disease: the first reported chinese patient

eIF2B-related disorders: antenatal onset and involvement of multiple organs