List of works - David J. Miller

A functional heat shock protein 90 chaperone is essential for efficient flock house virus RNA polymerase synthesis in Drosophila cells

scientific article

A targeted analysis of cellular chaperones reveals contrasting roles for heat shock protein 70 in flock house virus RNA replication

scientific article

Activation of the type I interferon pathway is enhanced in response to human neuronal differentiation.

scientific article

Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock House virus RNA replication

scientific article

Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

scientific journal article

Detecting protein-protein interaction in live yeast by flow cytometry

scientific article published in February 2005

Diagnosis and Management of Candida and Other Fungal Infections of the Head and Neck

scientific article published in June 2002

Discovery of anthranilamides as a novel class of inhibitors of neurotropic alphavirus replication

scientific article published on 11 February 2015

Discovery of potent broad spectrum antivirals derived from marine actinobacteria

scientific article (publication date: 2013)

Engineered Retargeting of Viral RNA Replication Complexes to an Alternative Intracellular Membrane ⬇️

scientific article published on November 1, 2003

Flock house virus RNA polymerase is a transmembrane protein with amino-terminal sequences sufficient for mitochondrial localization and membrane insertion

scientific article

Human neuronal cells possess functional cytoplasmic and TLR-mediated innate immune pathways influenced by phosphatidylinositol-3 kinase signaling.

scientific article

Identification of thieno[3,2-b]pyrrole derivatives as novel small molecule inhibitors of neurotropic alphaviruses

scientific article (publication date: April 2009)

In vivo self-interaction of nodavirus RNA replicase protein a revealed by fluorescence resonance energy transfer

scientific article published on July 2005

MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness

scientific article

Manipulation of host factors optimizes the pathogenesis of western equine encephalitis virus infections in mice for antiviral drug development

scientific article

Maturation-dependent responses of human neuronal cells to western equine encephalitis virus infection and type I interferons

scientific article published on 26 November 2007

Mitochondrion-enriched anionic phospholipids facilitate flock house virus RNA polymerase membrane association

scientific article published on 25 February 2009

Neurotropic arboviruses induce interferon regulatory factor 3-mediated neuronal responses that are cytoprotective, interferon independent, and inhibited by Western equine encephalitis virus capsid

scientific article published on 28 November 2012

Novel Inhibitors of Neurotropic Alphavirus Replication That Improve Host Survival in a Mouse Model of Acute Viral Encephalitis ⬇️

scientific article published on April 3, 2012

Novel indole-2-carboxamide compounds are potent broad-spectrum antivirals active against western equine encephalitis virus in vivo.

scientific article

Optimization of novel indole-2-carboxamide inhibitors of neurotropic alphavirus replication

scientific article

Restriction of Rift Valley Fever Virus Virulence in Mosquito Cells ⬇️

scientific article published on February 17, 2010

Role of cellular lipids in positive-sense RNA virus replication complex assembly and function

scientific article published on 29 April 2010

Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses

scientific article

The combined use of alphavirus replicons and pseudoinfectious particles for the discovery of antivirals derived from natural products

scientific article published on 30 December 2014

The heat shock protein 70 cochaperone YDJ1 is required for efficient membrane-specific flock house virus RNA replication complex assembly and function in Saccharomyces cerevisiae

scientific article

Three-dimensional analysis of a viral RNA replication complex reveals a virus-induced mini-organelle

scientific article (publication date: September 2007)

List of works by David J. Miller

A functional heat shock protein 90 chaperone is essential for efficient flock house virus RNA polymerase synthesis in Drosophila cells

A targeted analysis of cellular chaperones reveals contrasting roles for heat shock protein 70 in flock house virus RNA replication

Activation of the type I interferon pathway is enhanced in response to human neuronal differentiation.

Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock House virus RNA replication

Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

Detecting protein-protein interaction in live yeast by flow cytometry

Diagnosis and Management of Candida and Other Fungal Infections of the Head and Neck

Discovery of anthranilamides as a novel class of inhibitors of neurotropic alphavirus replication

Discovery of potent broad spectrum antivirals derived from marine actinobacteria

Engineered Retargeting of Viral RNA Replication Complexes to an Alternative Intracellular Membrane ⬇️

Flock house virus RNA polymerase is a transmembrane protein with amino-terminal sequences sufficient for mitochondrial localization and membrane insertion

Human neuronal cells possess functional cytoplasmic and TLR-mediated innate immune pathways influenced by phosphatidylinositol-3 kinase signaling.

Identification of thieno[3,2-b]pyrrole derivatives as novel small molecule inhibitors of neurotropic alphaviruses

In vivo self-interaction of nodavirus RNA replicase protein a revealed by fluorescence resonance energy transfer

MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness

Manipulation of host factors optimizes the pathogenesis of western equine encephalitis virus infections in mice for antiviral drug development

Maturation-dependent responses of human neuronal cells to western equine encephalitis virus infection and type I interferons

Mitochondrion-enriched anionic phospholipids facilitate flock house virus RNA polymerase membrane association

Neurotropic arboviruses induce interferon regulatory factor 3-mediated neuronal responses that are cytoprotective, interferon independent, and inhibited by Western equine encephalitis virus capsid

Novel Inhibitors of Neurotropic Alphavirus Replication That Improve Host Survival in a Mouse Model of Acute Viral Encephalitis ⬇️

Novel indole-2-carboxamide compounds are potent broad-spectrum antivirals active against western equine encephalitis virus in vivo.

Optimization of novel indole-2-carboxamide inhibitors of neurotropic alphavirus replication

Restriction of Rift Valley Fever Virus Virulence in Mosquito Cells ⬇️

Role of cellular lipids in positive-sense RNA virus replication complex assembly and function

Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses

The combined use of alphavirus replicons and pseudoinfectious particles for the discovery of antivirals derived from natural products

The heat shock protein 70 cochaperone YDJ1 is required for efficient membrane-specific flock house virus RNA replication complex assembly and function in Saccharomyces cerevisiae

Three-dimensional analysis of a viral RNA replication complex reveals a virus-induced mini-organelle