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List of works by Carl E. Frasch

A comparison of the serum agar grouping and slide agglutination methods for the identification of Neisseria meningitidis strains ⬇️

scientific article published on January 1, 1977

A method for purification of bacterial R-type lipopolysaccharides (lipooligosaccharides)

scientific article published on 01 February 1987

A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels ⬇️

scientific article published on January 1, 1982

Adherence of Isolates of Neisseria meningitidis from Patients and Carriers to Human Buccal Epithelial Cells ⬇️

scientific article published on October 1, 1980

Amplification of rDNA loci to detect and type Neisseria meningitidis and other eubacteria

scientific article published on 01 February 1993

An ELISA study of the antibody response after vaccination with a combined meningococcal group B polysaccharide and serotype 2 outer membrane protein vaccine.

scientific article

An analytical model applied to a multicenter pneumococcal enzyme-linked immunosorbent assay study

scientific article

An outer membrane protein of Neisseria meningitidis group B responsible for serotype specificity

scientific article published on July 1974

Analysis of Neisseria meningitidis class 3 outer membrane protein gene variable regions and type identification using genetic techniques.

scientific article

Analysis of damage to human ciliated nasopharyngeal epithelium by Neisseria meningitidis

scientific article published on February 1986

Antibody response of adults to an aluminum hydroxide-adsorbed Neisseria meningitidis serotype 2b protein-group B polysaccharide vaccine

scientific article published on 01 October 1988

Antibody response to infection in multiple myeloma. Implications for vaccination

scientific article published on August 1979

Antibody studies in mice of outer membrane antigens for use in an improved meningococcal B and C vaccine

scientific article published on 01 January 1996

Appearance of new strains associated with group B meningococcal disease and their use for rapid vaccine development

scientific article published on January 1987

Bactericidal antibody is the immunologic surrogate of protection against meningococcal disease

scientific article published on 21 May 2009

Bactericidal antibody responses of juvenile rhesus monkeys immunized with group B Neisseria meningitidis capsular polysaccharide-protein conjugate vaccines.

scientific article published on March 1997

Binding diversity of monoclonal antibodies to alpha(2-->8) polysialic acid conjugated to outer membrane vesicle via adipic acid dihydrazide.

scientific article

Capsular polysaccharide-protein conjugate vaccines of carbotype 1 Vibrio vulnificus: construction, immunogenicity, and protective efficacy in a murine model

scientific article

Capsular serotype of Staphylococcus aureus in the era of community-acquired MRSA ⬇️

scientific article published on July 18, 2011

Characterization and immunogenicity of meningococcal group C conjugate vaccine prepared using hydrazide-activated tetanus toxoid

scientific article published on 7 August 2007

Characterization of a stress protein from group B Neisseria meningitidis

scientific article published on June 1993

Characterization of antibodies to capsular polysaccharide antigens of Haemophilus influenzae type b and Streptococcus pneumoniae in human immune globulin intravenous preparations

scientific article

Chemical analysis of major outer membrane proteins of Neisseria meningitidis: comparison of serotypes 2 and 11

scientific article published on January 1980

Class-specific antibody response to group B Neisseria meningitidis capsular polysaccharide: use of polylysine precoating in an enzyme-linked immunosorbent assay

scientific article

Class-specific human bactericidal antibodies to capsular and noncapsular surface antigens of Neisseria meningitidis

scientific article published on 01 March 1984

Classification of Neisseria meningitidis Group B into Distinct Serotypes IV. Preliminary Chemical Studies on the Nature of the Serotype Antigen ⬇️

scientific article published on November 1, 1972

Classification of Neisseria meningitidis Group B into Distinct Serotypes. III. Application of a New Bactericidal-Inhibition Technique to Distribution of Serotypes among Cases and Carriers ⬇️

scientific article published on February 1, 1973

Classification of Neisseria meningitidis group B into distinct serotypes. I. Serological typing by a microbactericidal method

scientific article

Classification of Neisseria meningitidis group B into distinct serotypes. II. Extraction of type-specific antigens for serotyping by precipitin techniques.

scientific article

Clinical characteristics of a novel 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine candidate (PHiD-CV). Introduction

scientific article published in April 2009

Comparison of Neisseria meningitidis serogroup W135 polysaccharide-tetanus toxoid conjugate vaccines made by periodate activation of O-acetylated, non-O-acetylated and chemically de-O-acetylated polysaccharide

scientific article published on 29 June 2007

Correlates of immunity for pneumococcal conjugate vaccines ⬇️

scientific article published on May 16, 2003

Correlation between Serological and Sequencing Analyses of the PorB Outer Membrane Protein in the Neisseria meningitidis Serotyping System ⬇️

scientific article published on May 1, 1998

Description and nomenclature of Neisseria meningitidis capsule locus

scientific article published on April 2013

Detection and quantitation of the glucuronoxylomannan-like polysaccharide antigen from clinical and nonclinical isolates of Trichosporon beigelii and implications for pathogenicity

scientific article published on January 1995

Development and evaluation of pneumococcal conjugate vaccines: clinical trials and control tests

scientific article

Development of a Neisseria meningitidis group B serotype 2b protein vaccine and evaluation in a mouse model

scientific article

Development of a group A meningococcal conjugate vaccine,MenAfriVacTM ⬇️

scientific article published on April 12, 2012

Development of a second generation group B meningococcal vaccine

scientific article published on December 1, 1991

Diagnostic value of interactions between members of the family Neisseriaceae and lectins.

scientific article published on March 1984

Differential capacities of outer membrane proteins from Neisseria meningitidis B to prime the murine immune system after vaccination

scientific article published on January 2007

Effect of O acetylation of Neisseria meningitidis serogroup A capsular polysaccharide on development of functional immune responses

scientific article

Effect of a booster dose of serogroup B meningococcal vaccine on antibody response to Neisseria meningitidis in mice vaccinated with different immunization schedules

scientific article published in April 2005

Emergence of a new clone of serogroup C Neisseria meningitidis in São Paulo, Brazil ⬇️

scientific article published on May 1, 1992

Enzyme-linked immunosorbent assay for quantitation of human antibodies to pneumococcal polysaccharides

scientific article

Estimation of group B streptococcus type III polysaccharide-specific antibody concentrations in human sera is antigen dependent

scientific article

Evaluation of Previously Assigned Antibody Concentrations in Pneumococcal Polysaccharide Reference Serum 89SF by the Method of Cross-Standardization ⬇️

scientific article published on March 1, 1998

Evaluation of pneumococcal polysaccharide immunoassays using a 22F adsorption step with serum samples from infants vaccinated with conjugate vaccines

scientific article

Evaluation of the antiserum agar method for the serogroup identification of Neisseria meningitidis ⬇️

scientific article published on June 1, 1979

Expression of Neisseria meningitidis iron-regulated outer membrane proteins, including a 70-kilodalton transferrin receptor, and their potential for use as vaccines

scientific article

Five structural classes of major outer membrane proteins in Neisseria meningitidis

scientific article

Genetic and immunologic characterization of a novel serotype 4, 15 strain of Neisseria meningitidis

scientific article published in November 2000

Genetic relationships and clonal population structure of serotype 2 strains of Neisseria meningitidis.

scientific article published on June 1987

Genetic structure of Neisseria meningitidis populations in relation to serogroup, serotype, and outer membrane protein pattern

scientific article

Haemophilus b Disease After Vaccination With Haemophilus b Polysaccharide or Conjugate Vaccine

scientific article published on 01 December 1991

Heat-modifiable outer membrane proteins of Neisseria meningitidis and their organization within the membrane ⬇️

scientific article published on December 1, 1978

Heterogeneity and variation among Neisseria meningitidis lipopolysaccharides.

scientific article

High burden of invasive Streptococcus agalactiae disease in South African infants

scientific article published in March 2003

Human immune response to epitopes on the meningococcal outer membrane class 5 protein following natural infection

scientific article published on 01 September 1996

Human opsonins to meningococci after vaccination.

scientific article published on December 1984

Identification of variable region differences in Neisseria meningitidis class 3 protein sequences among five group B serotypes

scientific article published on December 1, 1992

Immune response of Brazilian children to a Neisseria meningitidis serogroup B outer membrane protein vaccine: comparison with efficacy

scientific article

Immune response to native NadA from Neisseria meningitidis and its expression in clinical isolates in Brazil

scientific article published on 01 February 2003

Immunization with meningococcal outer-membrane protein vesicles containing lipooligosaccharide protects mice against lethal experimental group B Neisseria meningitidis infection and septic shock

scientific article published in September 1999

Immunogenic and protective properties of meningococcal serotype 2a protein in the hen-embryo model

scientific article published on 01 November 1983

Immunogenicity in mice of pneumococcal glycoconjugate vaccines using pneumococcal protein carriers

scientific article published on 01 April 2001

Immunogenicity of Lipopolysaccharide Derived from Brucella abortus: Potential as a Carrier in Development of Vaccines for AIDS ⬇️

scientific article published on January 1, 1991

Immunologic and genetic characterization of lipooligosaccharide variants in a Neisseria meningitidis serogroup C strain

scientific article published on 01 November 2002

Immunotype epitopes of Neisseria meningitidis lipooligosaccharide types 1 through 8.

scientific article

Impact of the Conjugation Method on the Immunogenicity of Streptococcus pneumoniae Serotype 19F Polysaccharide in Conjugate Vaccines ⬇️

scientific article published on December 1, 2010

Induction of group 17 specific antibodies by pneumococcal type 17F and 17A polysaccharide vaccines

scientific article published on 01 March 2001

Induction of iron regulated proteins during normal growth of Neisseria meningitidis in a chemically defined medium

scientific article published on 01 July 1994

Inhibition enzyme-linked immunosorbent assay for serotyping of group B streptococcal isolates

scientific article

Intercontinental spread of Neisseria meningitidis clones of the ET-5 complex

scientific article published in January 1987

Intercontinental spread of a genetically distinctive complex of clones of Neisseria meningitidis causing epidemic disease

scientific article published on July 1986

Interlaboratory study evaluating quantitation of antibodies to Haemophilus influenzae type b polysaccharide by enzyme-linked immunosorbent assay.

scientific article

Invasive meningococcal disease: secondary spread in a day-care center.

scientific article

Involvement of phospholipid end groups of group C Neisseria meningitidis and Haemophilus influenzae type b polysaccharides in association with isolated outer membranes and in immunoassays

scientific article published on February 1994

Level of maternal IgG anti-group B streptococcus type III antibody correlated with protection of neonates against early-onset disease caused by this pathogen

scientific article published on 28 July 2004

Level of maternal antibody required to protect neonates against early-onset disease caused by group B Streptococcus type Ia: a multicenter, seroepidemiology study

scientific article published on 31 August 2001

Lipopolysaccharide (LPS) from Brucella abortus is less toxic than that from Escherichia coli, suggesting the possible use of B. abortus or LPS from B. abortus as a carrier in vaccines ⬇️

scientific article published on April 1, 1992

Lot-release criteria, postlicensure quality control, and the Haemophilus influenzae type b conjugate vaccines

scientific article published on 01 March 1995

Measurements of lipopolysaccharide (endotoxin) in meningococcal protein and polysaccharide preparations for vaccine usage

scientific article

Meningitis caused by a nonencapsulated strain of Neisseria meningitidis in twin infants with a C6 deficiency

scientific article published on 01 April 1987

Meningococcal Disease Caused by Neisseria meningitidis Serogroup B Serotype 4 in São Paulo, Brazil, 1990 to 1996 ⬇️

scientific article published on March 1, 1998

Meningococcal Disease in Alabama ⬇️

scientific article published on March 1, 1978

Meningococcal colonization and infection in children and their household contacts ⬇️

scientific article published on May 1, 1979

Meningococcal disease in the United States--1986. Meningococcal Disease Study Group

scientific article

Meningococcal group B vaccine trial in Norway 1981--1982. Preliminary report of results available November 1982

scientific article published on 01 December 1983

Meningococcal vaccines and disease due to other serogroups ⬇️

scientific article published on October 28, 1978

Monoclonal antibody to serotype 17 of Neisseria meningitidis and their prevalence in Brazilian states

scientific article published on 01 January 1995

Morphological differences in Neisseria meningitidis pili

scientific article published on September 1988

Multicenter comparison of Neisseria meningitidis serogroup C anti-capsular polysaccharide antibody levels measured by a standardized enzyme-linked immunosorbent assay.

scientific article

Multicenter comparison of levels of antibody to the Neisseria meningitidis group A capsular polysaccharide measured by using an enzyme-linked immunosorbent assay ⬇️

scientific article published on January 1, 1992

Multilaboratory evaluation of a viability assay for measurement of opsonophagocytic antibodies specific to the capsular polysaccharides of Streptococcus pneumoniae

scientific article

Natural bactericidal activity of human serum against Neisseria meningitidis isolates of different serogroups and serotypes

scientific article

Ongoing group B Neisseria meningitidis epidemic in São Paulo, Brazil, due to increased prevalence of a single clone of the ET-5 complex ⬇️

scientific article published on July 1, 1992

Outer membrane antigens of Neisseria meningitidis group B serotype 2 studied by crossed immunoelectrophoresis ⬇️

scientific article published on September 1, 1979

Outer membrane protein vesicle vaccines for meningococcal disease

scientific article

Outer membrane proteins of Neisseria meningitidis: structure and importance in meningococcal disease

scientific article published on 01 January 1986

Outer membrane vesicles (OMVs) and detoxified lipooligosaccharide (dLOS) obtained from Brazilian prevalent N. meningitidis serogroup B strains protect mice against homologous and heterologous meningococcal infection and septic shock

scientific article

Phylogenetic lineages of invasive and colonizing strains of serotype III group B Streptococci from neonates: a multicenter prospective study

scientific article

Pneumococcal capsular polysaccharide preparations may contain non-C-polysaccharide contaminants that are immunogenic

scientific article

Pneumococcal type 22f polysaccharide absorption improves the specificity of a pneumococcal-polysaccharide enzyme-linked immunosorbent assay

scientific article published on March 2001

Preclinical evaluation of group B Neisseria meningitidis and Escherichia coli K92 capsular polysaccharide-protein conjugate vaccines in juvenile rhesus monkeys

scientific article published on March 1997

Preparation and characterization of an immunogenic meningococcal group A conjugate vaccine for use in Africa

scientific article published on 6 December 2008

Preparation of bacterial polysaccharide-protein conjugates: analytical and manufacturing challenges

scientific article published on 24 June 2009

Production and control of Neisseria meningitidis vaccines

scientific article published on January 1990

Prophylaxis against Neisseria meningitidis infections and antibody responses in patients with deficiency of the sixth component of complement

scientific article published in May 1990

Proposed Standardization of Neisseria meningitidis PorA Variable-Region Typing Nomenclature ⬇️

scientific article published on November 1, 1998

Prospects for the prevention of meningococcal disease: special reference to group B

scientific article published on 01 March 1987

Protection against group B Neisseria meningitidis disease: effect of serogroup B polysaccharide and polymyxin B on immunogenicity of serotype protein preparations

scientific article

Protection against group B Neisseria meningitidis disease: preparation of soluble protein and protein-polysaccharide immunogens

scientific article

Protection against group B meningococcal disease. I. Comparison of group-specific and type-specific protection in the chick embryo model ⬇️

scientific article published on August 1, 1976

Protection against group B meningococcal disease. II. Infection and resulting immunity in a guinea pig model ⬇️

scientific article published on March 1, 1978

Protection against group B meningococcal disease. III. Immunogenicity of serotype 2 vaccines and specificity of protection in a guinea pig model ⬇️

scientific article published on March 1, 1978

Protection against group B meningococcal disease: evaluation of serotype 2 protein vaccines in a mouse bacteremia model ⬇️

scientific article published on October 1, 1979

Protective immunity of pneumococcal glycoconjugates

scientific article published on January 2003

Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines

scientific article

Quantification of bacterial polysaccharides by the purpald assay: measurement of periodate-generated formaldehyde from glycol in the repeating unit

scientific article published in September 2001

Quantitation of human IgG subclass antibodies to Haemophilus influenzae type b capsular polysaccharide. Results of an international collaborative study using enzyme immunoassay methodology

scientific article published on 01 April 1992

Rapid serogroup identification of Neisseria meningitidis by using antiserum agar: Prevalence of serotypes in a disease-free military population ⬇️

scientific article published on September 1, 1979

Re-emergence of meningococcal carriage on three-year follow-up of a kibbutz population after whole-community chemoprophylaxis

scientific article published on 01 July 1993

Recent developments in Neisseria meningitidis group A conjugate vaccines

scientific article

Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer

scientific article published on 16 October 2005

Risk factors for carriage of meningococcus in the Los Angeles County men's jail system

scientific article published in February 1991

Role of Protein Serotype Antigens in Protection against Disease Due to Neisseria meningitidis ⬇️

scientific article published on August 1, 1977

Role of lipopolysaccharide in wheat germ agglutinin-mediated agglutination of Neisseria meningitidis and Neisseria gonorrhoeae.

scientific article published on October 1980

Safety of vaccines containing meningococcal group B polysaccharide ⬇️

scientific article published on July 21, 1984

Seroepidemiologic aspects of Neisseria meningitidis in homosexual men

scientific article published on January 1982

Serogroup and serotype classification of bacterial pathogens

scientific article published on January 1994

Serogroup identification of Neisseria meningitidis: comparison of an antiserum agar method with bacterial slide agglutination ⬇️

scientific article published on May 1, 1978

Serogroup identification of meningococci by a modified antiserum agar method ⬇️

scientific article published on April 1, 1979

Serotype antigens of Neisseria meningitidis and a proposed scheme for designation of serotypes

scientific article published on July 1985

Serotypes and polyacrylamide gel electrophoresis types among disease-associated isolates of group B Neisseria meningitidis in Spain, 1976-1979.

scientific article published in August 1983

Sodium dodecyl sulfate-polyacrylamide gel typing system for characterization of Neisseria meningitidis isolates.

scientific article published on August 1982

Specificity of antibodies to O-acetyl-positive and O-acetyl-negative group C meningococcal polysaccharides in sera from vaccinees and carriers.

scientific article published on December 1991

Specificity of human antibodies reactive with pneumococcal C polysaccharide

scientific article published on April 2000

Spectrum of disease due to Haemophilus influenzae type b occurring in vaccinated children

scientific article published on 01 August 1988

Standardization and a multilaboratory comparison of Neisseria meningitidis serogroup A and C serum bactericidal assays. The Multilaboratory Study Group.

scientific article

Status of a group B Neisseria meningitidis vaccine

scientific article published in December 1985

Strain-specific variation in the protein and lipopolysaccharide composition of the group B meningococcal outer membrane ⬇️

scientific article published on August 1, 1976

Strains of Neisseria meningitidis isolated from patients and their close contacts.

scientific article

Structural characterization of the lipid A component of pathogenic Neisseria meningitidis ⬇️

scientific article published on March 1, 1992

Sudden-onset deafness. Serodiagnosis of recent meningococcal infection

scientific article published in November 1989

Surface antigen analysis of group B Neisseria meningitis outer membrane by monoclonal antibodies: identification of bactericidal antibodies to class 5 protein

scientific article published on 01 September 1995

Technical Development of a New Meningococcal Conjugate Vaccine

scientific article

The immunogenicity of Haemophilus influenzae type b conjugate vaccines in children born to human immunodeficiency virus-infected women. Women and Infants Transmission Study Group

scientific article published in May 1998

The use of oligonucleotide probes for meningococcal serotype characterization ⬇️

scientific article published on 01 March 1998

Use of opsonophagocytosis for serological evaluation of pneumococcal vaccines

scientific article

Vaccines for prevention of meningococcal disease

scientific article published on 01 April 1989

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