List of works by Ichinosuke Hyodo

A Phase II study of irinotecan in combination with 120-h infusion of 5-fluorouracil in patients with metastatic colorectal carcinoma: Japan Clinical Oncology Group Study (JCOG9703).

scientific article published in January 2003

A Rare Case of Colonic Leiomyosarcoma in Association with Ulcerative Colitis

scientific article published on October 2016

A case of advanced gastric cancer showing HER2 positivity after chemotherapy

scientific article published on 03 April 2020

A case of pancreatic-pleural fistula of Type 1 autoimmune pancreatitis successfully treated with pancreatic drainage and steroid

scientific article published on 28 April 2020

A case report: Long-term complete response of metastatic hepatocellular carcinoma obtained after discontinuation of 2-month sorafenib monotherapy

scientific article published on 15 June 2020

A clinical study using octreotide in relieving gastrointestinal symptoms due to bowel obstruction in a terminally ill cancer patient

scientific article published in September 2004

A feasibility study of oxaliplatin (L-OHP) in combination with infusional 5-FU/l-LV (FOLFOX4 regimen) for advanced colorectal cancer

scientific article

A phase 3 non-inferiority study of 5-FU/l-leucovorin/irinotecan (FOLFIRI) versus irinotecan/S-1 (IRIS) as second-line chemotherapy for metastatic colorectal cancer: updated results of the FIRIS study

scientific article published on 09 August 2014

A phase I study of doxifluridine combined with weekly paclitaxel for metastatic gastric cancer

scientific article published on 13 April 2005

A phase I study on combined therapy with proton-beam radiotherapy and in situ tumor vaccination for locally advanced recurrent hepatocellular carcinoma

scientific article published on 16 October 2013

A phase II Study of the global dose and schedule of capecitabine in Japanese patients with metastatic colorectal cancer

scientific article published on 6 July 2006

A phase II study of S-1, oxaliplatin, oral leucovorin, and bevacizumab combination therapy (SOLA) in patients with unresectable metastatic colorectal cancer

scientific article published on 22 July 2015

A phase II study of biweekly mitomycin C and irinotecan combination therapy in patients with fluoropyrimidine-resistant advanced gastric cancer: a report from the Gastrointestinal Oncology Group of the Japan Clinical Oncology Group (JCOG0109-DI Tria

scientific article published on 19 April 2011

A phase II study of sequential methotrexate and 5-fluorouracil chemotherapy in previously treated gastric cancer: a report from the Gastrointestinal Oncology Group of the Japan Clinical Oncology Group, JCOG 9207 trial

scientific article published on 30 May 2008

A randomized phase II study comparing S-1 plus weekly split-dose cisplatin with S-1 plus standard-dose cisplatin as first-line chemotherapy for advanced gastric cancer

scientific article published on 13 July 2013

A randomized phase II study of combination therapy with S-1, oral leucovorin, and oxaliplatin (SOL) and mFOLFOX6 in patients with previously untreated metastatic colorectal cancer.

scientific article

Acetaldehyde is an oxidative stressor for gastric epithelial cells

scientific article

Acetic acid is an oxidative stressor in gastric cancer cells

scientific article published on 03 April 2018

Alcohol is an oxidative stressor for gastric epithelial cells: detection of superoxide in living cells

scientific article published on 31 August 2013

Anal canal adenocarcinoma with neuroendocrine features accompanying secondary extramammary Paget disease, successfully treated with modified FOLFOX6: a case report

scientific article published on 20 November 2018

Antitumor effects of a sirtuin inhibitor, tenovin-6, against gastric cancer cells via death receptor 5 up-regulation

scientific article

Artificial hydration therapy, laboratory findings, and fluid balance in terminally ill patients with abdominal malignancies

scientific article published on 01 February 2006

Augmented antitumor activity of 5-fluorouracil by double knockdown of MDM4 and MDM2 in colon and gastric cancer cells

scientific article published on 16 January 2019

Bevacizumab in combination with irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) in patients with metastatic colorectal cancer who were previously treated with oxaliplatin-containing regimens: a multicenter observational cohort study (TCTG 2nd-B

scientific article published on 31 December 2011

Biological markers as a predictor for response and prognosis of unresectable gastric cancer patients treated with irinotecan and cisplatin

scientific article published on 22 November 2005

Cancer cells uptake porphyrinsviaheme carrier protein 1

Cellular membrane fluidity measurement by fluorescence polarization in indomethacin-induced gastric cellular injury in vitro

scientific article published on 25 December 2007

Clinical study of TS-1 therapy for inoperable and recurrent gastric cancer

scientific article published on April 1, 2003

Clinical study of gemcitabine therapy for recurrent or metastatic pancreatic cancer

scientific article published in September 2004

Clinical study of irinotecan plus infusional fluorouracil/l-leucovorin (FOLFIRI) in patients with fluoropyrimidine-resistant metastatic colorectal cancer

scientific article

Clinical study of irinotecan therapy in patients with fluoropyrimidine-resistant advanced colorectal cancer

scientific article published in September 2004

Collagenous sprue diagnosed by double balloon endoscopy.

scientific article

Correlations of survival with progression-free survival, response rate, and disease control rate in advanced biliary tract cancer: a meta-analysis of randomised trials of first-line chemotherapy

scientific article

Cyclophosphamide enhances antitumor efficacy of oncolytic adenovirus expressing uracil phosphoribosyltransferase (UPRT) in immunocompetent Syrian hamsters

scientific article published on 4 April 2013

Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice

scientific article published on 19 November 2009

Diagnosis of drug-induced liver injury in Japanese patients by criteria of Consensus Meetings in Europe

scientific article published on 01 January 2003

Docetaxel and cisplatin in patients with advanced or recurrent gastric cancer: a multicenter phase I/II study

scientific article published in January 2002

Does Repeated Lung Resection Provide Long-Term Survival for Recurrent Pulmonary Metastases of Colorectal Cancer? Results of a Retrospective Japanese Multicenter Study

scientific article published on 25 October 2016

E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers

scientific article published on May 2007

Early Tumor Shrinkage and Depth of Response in the Second-Line Treatment for KRAS exon2 Wild-Type Metastatic Colorectal Cancer: An Exploratory Analysis of the Randomized Phase 2 Trial Comparing Panitumumab and Bevacizumab in Combination with FOLFIRI

scientific article published on 22 September 2020

Early tumor shrinkage and depth of response in patients with advanced gastric cancer: a retrospective analysis of a randomized phase III study of first-line S-1 plus oxaliplatin vs. S-1 plus cisplatin

scientific article published on 09 June 2018

Effect of combined treatment with the epirubicin-incorporating micelles (NC-6300) and 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016) on a human gastric cancer model

scientific article published on 18 December 2013

Efficacy and safety of S-1 and oxaliplatin combination therapy in elderly patients with advanced gastric cancer.

scientific article published on 16 October 2015

Efficacy of adjuvant chemotherapy after resection of pulmonary metastasis from colorectal cancer: a propensity score-matched analysis

scientific article published on 22 November 2018

Efficacy of clinical pathway for the management of mucosal gastric carcinoma treated with endoscopic submucosal dissection using an insulated-tip diathermic knife.

scientific article

Endoscopic detachable snare ligation: a new treatment method for colonic diverticular hemorrhage

scientific article

Enhanced antitumor effect of anti-tissue factor antibody-conjugated epirubicin-incorporating micelles in xenograft models.

scientific article published on 23 March 2015

EpCAM- and EGFR-targeted selective gene therapy for biliary cancers using Z33-fiber-modified adenovirus

scientific article published on 6 January 2011

Extensive liver metastasis of gastric cancer effectively treated by hepatic arterial infusion of 5-fluorouracil/cisplatin

scientific article published on 01 September 2000

Extragonadal retroperitoneal embryonal carcinoma successfully treated with chemotherapy.

scientific article published on November 2003

FOLFIRI plus bevacizumab 5 mg/kg versus 10 mg/kg as second-line therapy in patients with metastatic colorectal cancer who have failed first-line bevacizumab plus oxaliplatin-based therapy: a randomized phase III study (EAGLE Study)

scientific article published on 12 December 2011

First-line chemotherapy with S-1 alone or S-1 plus cisplatin for elderly patients with advanced gastric cancer: a multicenter propensity score matched study

scientific article published on 20 January 2018

Five-weekly S-1 plus cisplatin therapy combined with trastuzumab therapy in HER2-positive gastric cancer: a phase II trial and biomarker study (WJOG7212G).

scientific article published on 11 May 2017

Fluorescence-based co-culture of normal and cancerous cells as an indicator of therapeutic effects in cancer

scientific article

Gastric Cancer Concomitant with Inflammatory Fibroid Polyp Treated with Endoscopic Mucosal Resection Using an Insulation-tip Diathermic Knife ⬇️

scientific article published on 01 March 2003

Gastric acid induces mitochondrial superoxide production and lipid peroxidation in gastric epithelial cells

scientific article

Genotype-directed, dose-finding study of irinotecan in cancer patients with UGT1A1*28 and/or UGT1A1*6 polymorphisms

scientific article published on 12 August 2011

Geranylgeranylacetone protects the human gastric mucosa from diclofenac-induced injury via induction of heat shock protein 70

scientific article published on 06 August 2007

Glasgow Prognostic Score predicts poor prognosis among advanced biliary tract cancer patients with good performance status

article

Global perspectives on chemotherapy for patients with gastric carcinoma: a roundtable discussion.

scientific article published on May 2007

Granular cell tumor occurring in the sigmoid colon treated by endoscopic mucosal resection using a transparent cap (EMR-C) ⬇️

scientific article published on January 1, 2003

Heterogeneity of Tumor Sizes in Multiple Pulmonary Metastases of Colorectal Cancer as a Prognostic Factor

scientific article published on 12 October 2016

High orotate phosphoribosyltransferase gene expression predicts complete response to chemoradiotherapy in patients with squamous cell carcinoma of the esophagus

scientific article published on 23 March 2009

Identification of a unique hepatocellular carcinoma line, Li-7, with CD13(+) cancer stem cells hierarchy and population change upon its differentiation during culture and effects of sorafenib

scientific article

Impact of progression type on overall survival in patients with advanced gastric cancer based on randomized phase III study of S-1 plus oxaliplatin versus S-1 plus cisplatin

scientific article published on 7 November 2016

Incidence and underlying etiologies of bronchial secretion in terminally ill cancer patients: a multicenter, prospective, observational study.

scientific article published in June 2004

Irinotecan plus S-1 (IRIS) versus fluorouracil and folinic acid plus irinotecan (FOLFIRI) as second-line chemotherapy for metastatic colorectal cancer: a randomised phase 2/3 non-inferiority study (FIRIS study).

scientific article published on 12 August 2010

Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2014 for treatment of colorectal cancer

scientific article

Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer.

scientific article published on 15 October 2011

Long-term outcomes of proton beam therapy in patients with previously untreated hepatocellular carcinoma.

scientific article published on 23 December 2016

Long-term survival and prognostic factors in patients with metastatic gastric cancers treated with chemotherapy in the Japan Clinical Oncology Group (JCOG) study

scientific article published in November 2004

MDM4 expression as an indicator of TP53 reactivation by combined targeting of MDM2 and MDM4 in cancer cells without TP53 mutation

scientific article

MUC4 interacts with ErbB2 in human gallbladder carcinoma: potential pathobiological implications

scientific article published on 07 April 2008

Mediastinal Neuroendocrine Carcinoma Slowly Growing for 8 Years after Surgical Resection of Esophageal Squamous Cell Carcinoma

scientific article published on 07 July 2020

Meta-analysis supporting noninferiority of oxaliplatin plus S-1 to cisplatin plus S-1 in first-line treatment of advanced gastric cancer (G-SOX study): indirect comparison with S-1 alone

scientific article

Mitochondrial reactive oxygen species accelerate the expression of heme carrier protein 1 and enhance photodynamic cancer therapy effect

scientific article published on 20 June 2014

Multicenter prospective study on efficacy and safety of octreotide for inoperable malignant bowel obstruction

scientific article published on 21 April 2010

Multiple synchronous early gastric carcinoma with seven lesions

scientific article published on 01 January 2003

NC-6300, an epirubicin-incorporating micelle, extends the antitumor effect and reduces the cardiotoxicity of epirubicin.

scientific article published on 19 April 2013

NSAIDs and acidic environment induce gastric mucosal cellular mitochondrial dysfunction

scientific article published on 19 January 2012

Neoplastic transformation and induction of H+,K+ -adenosine triphosphatase by N-methyl-N'-nitro-N-nitrosoguanidine in the gastric epithelial RGM-1 cell line

scientific article published on 22 November 2007

Newly developed endoscopic detachable snare ligation therapy for colonic diverticular hemorrhage: a multicenter phase II trial (with videos)

scientific article published on 19 April 2018

Oncolytic Virotherapy and Gene Therapy Strategies for Hepatobiliary Cancers

scientific article published on 30 March 2017

Optimal Maintenance Strategy for First-Line Oxaliplatin-Containing Therapy with or without Bevacizumab in Patients with Metastatic Colorectal Cancer: A Meta-Analysis

scientific article published on 01 December 2020

Outcomes and prognostic factors after pulmonary metastasectomy in patients with colorectal cancer with previously resected hepatic metastases

scientific article published on 11 January 2019

Outcomes of segmentectomy and wedge resection for pulmonary metastases from colorectal cancer

scientific article published on 01 March 2017

Panitumumab-induced interstitial lung disease in a case of metastatic colorectal cancer

scientific article published on 18 March 2013

Perceptions and attitudes of clinical oncologists on complementary and alternative medicine: a nationwide survey in Japan

scientific article

Peroxiredoxin I protects gastric mucosa from oxidative injury induced by H. pylori infection

scientific article published on 14 November 2007

Phase 1 study of efatutazone, a novel oral peroxisome proliferator-activated receptor gamma agonist, in combination with FOLFIRI as second-line therapy in patients with metastatic colorectal cancer

scientific article

Phase I clinical and pharmacokinetic study of S-1 plus oral leucovorin in patients with metastatic colorectal cancer.

scientific article

Phase I study of gemcitabine, cisplatin, and S-1 combination therapy for patients with untreated advanced biliary tract cancer

scientific article published on 15 April 2015

Phase II study of S-1 on alternate days plus bevacizumab in patients aged ≥ 75 years with metastatic colorectal cancer (J-SAVER)

scientific article published on 14 May 2019

Phase II study of a 4-week capecitabine regimen in advanced or recurrent gastric cancer

scientific article

Phase II study of biweekly irinotecan and mitomycin C combination therapy in patients with fluoropyrimidine-resistant advanced colorectal cancer

scientific article

Phase II study of first-line chemotherapy with uracil-tegafur plus oral leucovorin in elderly (≥75 years) Japanese patients with metastatic colorectal cancer: SGOSG-CR0501 study

scientific article published on 20 February 2014

Phase II study of oxaliplatin in japanese patients with metastatic colorectal cancer refractory to fluoropyrimidines

scientific article

Phase II study of sequential methotrexate and 5-fluorouracil chemotherapy against peritoneally disseminated gastric cancer with malignant ascites: a report from the Gastrointestinal Oncology Study Group of the Japan Clinical Oncology Group, JCOG 960

scientific article

Potent in vitro and in vivo antitumor activity of interleukin-4-conjugated Pseudomonas exotoxin against human biliary tract carcinoma

scientific article published on December 2008

Potent in vitro and in vivo antitumor activity of sorafenib against human intrahepatic cholangiocarcinoma cells

scientific article published on 18 February 2011

Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells

scientific article published on 12 January 2011

Predicting skin toxicity according to EGFR polymorphisms in patients with colorectal cancer receiving antibody against EGFR.

scientific article published in November 2013

Prediction of the effect of capecitabine in gastric cancer by immunohistochemical staining of thymidine phosphorylase and dihydropyrimidine dehydrogenase

scientific article published in September 2008

Predictive factors of lymph node metastasis in patients with undifferentiated early gastric cancers

scientific article published on 01 May 2006

Present status and perspectives of colorectal cancer in Asia: Colorectal Cancer Working Group report in 30th Asia-Pacific Cancer Conference

scientific article

Proton beam therapy combined with concurrent chemotherapy for esophageal cancer

scientific article published in March 2015

Qing Dai attenuates nonsteroidal anti-inflammatory drug-induced mitochondrial reactive oxygen species in gastrointestinal epithelial cells

scientific article published on November 2014

Randomised phase II study of panitumumab plus irinotecan versus cetuximab plus irinotecan in patients with KRAS wild-type metastatic colorectal cancer refractory to fluoropyrimidine, irinotecan and oxaliplatin (WJOG 6510G)

scientific article published on 08 June 2020

Randomised phase II trial of mFOLFOX6 plus bevacizumab versus mFOLFOX6 plus cetuximab as first-line treatment for colorectal liver metastasis (ATOM trial)

scientific article published on 09 July 2019

Randomized phase II/III study of 5-fluorouracil/l-leucovorin versus 5-fluorouracil/l-leucovorin plus paclitaxel administered to patients with severe peritoneal metastases of gastric cancer (JCOG1108/WJOG7312G)

scientific article published on 08 February 2020

Randomized phase III trial of fluorouracil alone versus fluorouracil plus cisplatin versus uracil and tegafur plus mitomycin in patients with unresectable, advanced gastric cancer: The Japan Clinical Oncology Group Study (JCOG9205).

scientific article published on January 2003

Randomized study of FOLFIRI plus either panitumumab or bevacizumab for wild-type KRAS colorectal cancer-WJOG 6210G.

scientific article published on 06 October 2016

Randomized, Phase II Study of Trastuzumab Beyond Progression in Patients With HER2-Positive Advanced Gastric or Gastroesophageal Junction Cancer: WJOG7112G (T-ACT Study)

scientific article published on 24 March 2020

Randomized, open-label, phase III study comparing irinotecan with paclitaxel in patients with advanced gastric cancer without severe peritoneal metastasis after failure of prior combination chemotherapy using fluoropyrimidine plus platinum: WJOG 400

scientific article published on 4 November 2013

Reactive oxygen species involved cancer cellular specific 5-aminolevulinic acid uptake in gastric epithelial cells

scientific article published on March 2014

Regular dose of gemcitabine induces an increase in CD14+ monocytes and CD11c+ dendritic cells in patients with advanced pancreatic cancer

scientific article published on October 2009

Reply

Reply

Retrospective analysis for the efficacy and safety of nivolumab in advanced gastric cancer patients according to ascites burden

scientific article published on 22 October 2020

Retrospective analysis on usefulness of somatostatin receptor scintigraphy for neuroendocrine neoplasm

scientific article published on 01 October 2017

Risk factors for submucosal and lymphovascular invasion in gastric cancer looking indicative for endoscopic submucosal dissection.

scientific article

S-1 plus leucovorin and oxaliplatin versus S-1 plus cisplatin as first-line therapy in patients with advanced gastric cancer (SOLAR): a randomised, open-label, phase 3 trial

scientific article published on 16 July 2020

S-1 plus leucovorin versus S-1 plus leucovorin and oxaliplatin versus S-1 plus cisplatin in patients with advanced gastric cancer: a randomised, multicentre, open-label, phase 2 trial

scientific article

Safety margin of radiofrequency ablation for hepatocellular carcinoma: a prospective study using magnetic resonance imaging with superparamagnetic iron oxide

scientific article published on 17 May 2019

Safety, tolerability, pharmacokinetics, and pharmacodynamics of the afucosylated, humanized anti-EPHA2 antibody DS-8895a: a first-in-human phase I dose escalation and dose expansion study in patients with advanced solid tumors

scientific article published on 14 August 2019

Seronegative alpha-fetoprotein-producing early gastric cancer treated with endoscopic mucosal resection and additional surgery

scientific article

Sex differences in the safety of S-1 plus oxaliplatin and S-1 plus cisplatin for patients with metastatic gastric cancer

scientific article published on 23 July 2019

Significance of biological markers for predicting prognosis and selecting chemotherapy regimens of advanced gastric cancer patients between continuous infusion of 5-FU and a combination of 5-FU and cisplatin

scientific article published on 01 April 2007

Splenic rupture caused by pancreatic pseudocyst successfully treated by endoscopic ultrasound-guided drainage

scientific article published on 08 June 2020

Study protocol of the B-CAST study: a multicenter, prospective cohort study investigating the tumor biomarkers in adjuvant chemotherapy for stage III colon cancer

scientific article

Successful Long-term Management with a Single Administration of Tri-weekly Nab-paclitaxel in a Patient with Advanced Gastric Cancer with Peritoneal Dissemination

scientific article

Successful Treatment with Modified FOLFOX6 and Panitumumab in a Cecal Cancer Patient Undergoing Hemodialysis.

scientific article

Surgical Outcome and Prognostic Stratification for Pulmonary Metastasis From Colorectal Cancer.

scientific article published on June 2017

TAS-118 (S-1 plus leucovorin) versus S-1 in patients with gemcitabine-refractory advanced pancreatic cancer: a randomised, open-label, phase 3 study (GRAPE trial)

scientific article published on 22 November 2018

The pathophysiology of non-steroidal anti-inflammatory drug (NSAID)-induced mucosal injuries in stomach and small intestine

scientific article published on 26 February 2011

The ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase in tumour tissues of patients with metastatic gastric cancer is predictive of the clinical response to 5'-deoxy-5-fluorouridine

scientific article

The sirtuin inhibitor tenovin-6 upregulates death receptor 5 and enhances cytotoxic effects of 5-fluorouracil and oxaliplatin in colon cancer cells.

scientific article published in January 2013

Time-dependent discrepancies between physician-assessed and patient-reported oxaliplatin-induced peripheral neuropathy in patients with metastatic colorectal cancer who received mFOLFOX6 plus bevacizumab: a post hoc analysis (WJOG4407GSS2)

scientific article published on 16 November 2020

Unresectable alpha fetoprotein-producing gastric cancer successfully treated with irinotecan and mitomycin C after S-1 failure

scientific article published in February 2004

Unusual metastasis of hepatocellular carcinoma to the esophagus.

scientific article published in May 2005

Uracil-Tegafur and Oral Leucovorin Combined With Bevacizumab in Elderly Patients (Aged ≥ 75 Years) With Metastatic Colorectal Cancer: A Multicenter, Phase II Trial (Joint Study of Bevacizumab, Oral Leucovorin, and Uracil-Tegafur in Elderly Patients

scientific article published on 17 December 2015

Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice

scientific article published on 7 August 2008

Utility of epirubicin-incorporating micelles tagged with anti-tissue factor antibody clone with no anticoagulant effect.

scientific article published on 17 December 2015

Validation of the JCOG prognostic index in advanced gastric cancer using individual patient data from the SPIRITS and G-SOX trials.

scientific article

WJOG6510G: Randomized phase II of Pmab + IRI vs Cmab + IRI for KRAS WT mCRC previously treated after FU, IRI, and L-OHP

scientific article published on 01 October 2017

Waterjet submucosal dissection of porcine esophagus with the HybridKnife and ERBEJET 2 system: a pilot study

scientific article published on January 2017

[A case of Cronkhite-Canada syndrome associated with cholangiocellular carcinoma]

scientific article published on 01 May 2005

[A case of malignant peritoneal mesothelioma with the epithelioid histological type, successfully treated with pemetrexed plus cisplatin]

[A retrospective analysis of cetuximab or panitumumab monotherapy for KRAS wild-type metastatic colorectal cancer in clinical practice]

scientific article published in February 2015

[Gene mutation (KRAS, BRAF, PIK3CA) and clinical benefit of anti-EGFR antibody]

scientific article published on 01 April 2011

[Malignant lymphoma with submucosal invasion in the terminal ileum diagnosed with colonoscopy and examined by endoscopic ultrasonography]

scientific article published on 01 January 2004

[Revision of the training curriculum of Japan Society of Gastroenterology: gastroenterologist's role and professionalism]

aCGH Analysis of Predictive Biomarkers for Response to Bevacizumab plus Oxaliplatin- or Irinotecan-Based Chemotherapy in Patients with Metastatic Colorectal Cancer

scientific article published on 13 November 2018

Paulina is supported by:

About Paulina

Help