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List of works by Ikuo Takashima

A PCR-based protocol for the generation of a recombinant West Nile virus

scientific article

A comparative epidemiological study of hantavirus infection in Japan and Far East Russia

scientific article published on February 2007

A conserved region in the prM protein is a critical determinant in the assembly of flavivirus particles.

scientific article published on 28 September 2011

A critical determinant of neurological disease associated with highly pathogenic tick-borne flavivirus in mice

scientific article

A new model of Hantaan virus persistence in mice: the balance between HTNV infection and CD8(+) T-cell responses

scientific article published on May 2004

Amino acid changes responsible for attenuation of virus neurovirulence in an infectious cDNA clone of the Oshima strain of tick-borne encephalitis virus

scientific article published on April 2004

Analysis of severe acute respiratory syndrome coronavirus structural proteins in virus-like particle assembly.

scientific article

Comparison of virulence of various hantaviruses related to hemorrhagic fever with renal syndrome in newborn mouse model

scientific article published on February 2004

Construction and application of chimeric virus-like particles of tick-borne encephalitis virus and mosquito-borne Japanese encephalitis virus

scientific article published on January 2008

Construction of a replicon and an infectious cDNA clone of the Sofjin strain of the Far-Eastern subtype of tick-borne encephalitis virus ⬇️

scientific article published on July 23, 2011

Construction of an infectious cDNA clone for Omsk hemorrhagic fever virus, and characterization of mutations in NS2A and NS5.

scientific article published on 15 September 2010

Continuity and Change of Japanese Encephalitis Virus in Toyama Prefecture, Japan ⬇️

scientific article published on May 1, 2011

Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections

scientific article published on April 2006

Detection of West Nile virus and Japanese encephalitis virus using real-time PCR with a probe common to both viruses

scientific article published on June 2005

Development of a serotyping enzyme-linked immunosorbent assay system based on recombinant truncated hantavirus nucleocapsid proteins for New World hantavirus infection ⬇️

scientific article published on June 18, 2012

Development of an ELISA system for tick-borne encephalitis virus infection in rodents ⬇️

scientific article published on February 1, 2011

Development of an enzyme-linked immunosorbent assay for serological diagnosis of tick-borne encephalitis using subviral particles

scientific article published on 15 March 2006

Different chemokine expression in lethal and non-lethal murine West Nile virus infection

scientific article published on November 2004

Discrimination of West Nile virus and Japanese encephalitis virus strains using RT-PCR RFLP analysis

scientific article published on January 2003

Ecology of hantaviruses in Mexico: Genetic identification of rodent host species and spillover infection ⬇️

scientific article published on June 29, 2012

Epidemiological study of hantavirus infection in the Samara Region of European Russia.

scientific article published on December 2009

Establishment of a neutralization test involving reporter gene-expressing virus-like particles of tick-borne encephalitis virus

scientific article published on 27 May 2009

Generation of congenic mouse strains by introducing the virus-resistant genes, Mx1 and Oas1b, of feral mouse-derived inbred strain MSM/Ms into the common strain C57BL/6J.

scientific article published on August 2009

Genetic and antigenic analyses of a Puumala virus isolate as a potential vaccine strain

scientific article published on November 2008

Genetic and antigenic characterization of the Amur virus associated with hemorrhagic fever with renal syndrome

scientific article

Genetic and biological characterization of tick-borne encephalitis virus isolated from wild rodents in southern Hokkaido, Japan in 2008.

scientific article published on 16 April 2013

Genetic characterization of hantaviruses transmitted by the Korean field mouse (Apodemus peninsulae), Far East Russia

scientific article published on August 2002

Genetic diversity of hantaviruses in Mexico: Identification of three novel hantaviruses from Neotominae rodents ⬇️

scientific article published on November 25, 2011

Glycosylation of the Envelope Protein of West Nile Virus Affects Its Replication in Chicks

scientific article published on December 1, 2011

Glycosylation of the West Nile Virus Envelope Protein Increases In Vivo and In Vitro Viral Multiplication in Birds

scientific article (publication date: April 2010)

Hantavirus-specific CD8(+)-T-cell responses in newborn mice persistently infected with Hantaan virus

scientific article

Increased pathogenicity of West Nile virus (WNV) by glycosylation of envelope protein and seroprevalence of WNV in wild birds in Far Eastern Russia

scientific article published on 12 December 2013

Infection of Hantaan virus strain AA57 leading to pulmonary disease in laboratory mice ⬇️

scientific article published on October 21, 2011

Isolation and characterization of hantaviruses in Far East Russia and etiology of hemorrhagic fever with renal syndrome in the region.

scientific article published on March 2012

Packaging the replicon RNA of the Far-Eastern subtype of tick-borne encephalitis virus into single-round infectious particles: development of a heterologous gene delivery system

scientific article published on 25 March 2005

Puumala virus infection in Syrian hamsters (Mesocricetus auratus) resembling hantavirus infection in natural rodent hosts ⬇️

scientific article published on June 6, 2011

Role of the N-linked glycans of the prM and E envelope proteins in tick-borne encephalitis virus particle secretion

scientific article published on April 2005

Seroprevalence of West Nile virus in wild birds in far eastern Russia using a focus reduction neutralization test.

scientific article

Single point mutation in tick-borne encephalitis virus prM protein induces a reduction of virus particle secretion

scientific article published on October 2004

Soochong virus: an antigenically and genetically distinct hantavirus isolated from Apodemus peninsulae in Korea

scientific article

Susceptibility to flavivirus-specific antiviral response of Oas1b affects the neurovirulence of the Far-Eastern subtype of tick-borne encephalitis virus ⬇️

scientific article published on December 25, 2012

The N-terminus of the Montano virus nucleocapsid protein possesses broadly cross-reactive conformation-dependent epitopes conserved in rodent-borne hantaviruses ⬇️

scientific article published on April 19, 2012

The kinetics of proinflammatory cytokines in murine peritoneal macrophages infected with envelope protein-glycosylated or non-glycosylated West Nile virus.

scientific article

The pathogenesis of 3 neurotropic flaviviruses in a mouse model depends on the route of neuroinvasion after viremia

scientific article published on March 2015

Viral envelope protein glycosylation is a molecular determinant of the neuroinvasiveness of the New York strain of West Nile virus

scientific article published on December 2004

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