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List of works by Leda Bassit

2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture.

scientific article published on 8 June 2017

Acute acalculous cholecystitis during Zika virus infection in an immunocompromised patient

scientific article published on 24 November 2017

Adenosine Dioxolane Nucleoside Phosphoramidates as Antiviral Agents for Human Immunodeficiency and Hepatitis B Viruses

scientific article published on August 2013

Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides

scientific article published on 13 July 2009

Approaches to hepatitis C treatment and cure using NS5A inhibitors

scientific article published on 05 March 2014

Cellular pharmacology and potency of HIV-1 nucleoside analogs in primary human macrophages

scientific article published on 21 December 2012

Characterization of dengue virus 2 growth in megakaryocyte-erythrocyte progenitor cells

scientific article

Combinations of 2'-C-methylcytidine analogues with interferon-alpha2b and triple combination with ribavirin in the hepatitis C virus replicon system

scientific article

Efficacy and safety of 3-week response-guided triple direct-acting antiviral therapy for chronic hepatitis C infection: a phase 2, open-label, proof-of-concept study

scientific article

Evaluation of Single and Combination Therapies with Tenofovir Disoproxil Fumarate and Emtricitabine In Vitro and in a Robust Mouse Model Supporting High Levels of Hepatitis B Virus Replication ⬇️

scientific article published on September 17, 2012

Jak Inhibitors Modulate Production of Replication-Competent Zika Virus in Human Hofbauer, Trophoblasts, and Neuroblastoma cells

scientific article published on 24 May 2017

Long-term exposure to AZT, but not d4T, increases endothelial cell oxidative stress and mitochondrial dysfunction

scientific article published on 09 December 2008

Quantifying mixed populations of drug-resistant human immunodeficiency virus type 1.

scientific article

Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome

scientific article published in 2010

Synthesis and Anti-Hepatitis B Virus and Anti-Hepatitis C Virus Activities of 7-Deazaneplanocin A Analogues in Vitro

scientific article (publication date: 8 January 2009)

Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl-7-deazapurine nucleosides, their phosphoramidate prodrugs and 5'-triphosphates ⬇️

scientific article published on September 29, 2011

Synthesis and antiviral evaluation of 2′,2′,3′,3′-tetrafluoro nucleoside analogs

scientific article

Synthesis and antiviral evaluation of fluorinated acyclo-nucleosides and their phosphoramidates

scientific article published on 19 October 2016

Synthesis and antiviral evaluation of novel heteroarylpyrimidines analogs as HBV capsid effectors

scientific article published on 6 January 2017

Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector

scientific article published on 29 June 2017

Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3′-azido-2′,3′-dideoxypurine nucleosides ⬇️

scientific article published on May 30, 2011

Toward Elimination of Hepatitis B Virus Using Novel Drugs, Approaches, and Combined Modalities

scientific article

Towards HBV curative therapies

scientific article published in February 2018

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network

scientific article

β-D-2'-C-Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5'-Triphosphate Forms

scientific article

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