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List of works by Lucy Dorrell

A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A.

scientific article published on 30 January 2013

A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques

scientific article

A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans

scientific article published in April 2004

Antiviral Inhibitory Capacity of CD8+ T cells Predicts the Rate of CD4+ T-Cell Decline in HIV-1 Infection ⬇️

scientific article published on June 18, 2012

Aviremia 10 Years Postdiscontinuation of Antiretroviral Therapy Initiated During Primary Human Immunodeficiency Virus-1 Infection and Association With Gag-Specific T-Cell Responses

scientific article

Clinical experience with plasmid DNA- and modified vaccinia virus Ankara-vectored human immunodeficiency virus type 1 clade A vaccine focusing on T-cell induction

scientific article published on January 2007

Comment on clinical development of candidate HIV vaccines: different problems for different vaccines

scientific article published on April 2014

Comprehensive analysis of HIV Gag-specific IFN-gamma response in HIV-1- and HIV-2-infected asymptomatic patients from a clinical cohort in The Gambia

scientific article published in December 2008

Comprehensive cardiac magnetic resonance imaging and spectroscopy reveals a high burden of myocardial disease in HIV infection.

scientific article published on 30 January 2013

Control of HIV-1 replication in vitro by vaccine-induced human CD8(+) T cells through conserved subdominant Pol epitopes

scientific article published on 16 January 2016

Defining the HLA class I-associated viral antigen repertoire from HIV-1-infected human cells

scientific article published on 15 October 2015

Design and pre-clinical evaluation of a universal HIV-1 vaccine

scientific article published in 2007

Detecting asymptomatic Trichomonas vaginalis in females using the BD ProbeTec™ Trichomonas vaginalis Qx nucleic acid amplification test

scientific article published on 5 May 2016

Detection of broad functional gag-specific CD4+ T cell responses in HIV-1-infected subjects following therapeutic immunization with rMVA expressing an HIV-1 gag immunogen.

scientific article published on 21 December 2006

Development of prophylactic vaccines against HIV-1.

scientific article published on 17 July 2013

Discovery of a PCAF Bromodomain Chemical Probe

scientific article published on 14 December 2016

Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells

scientific article published on 25 March 2015

Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors.

scientific article published on 12 July 2016

Emergence of a distinct HIV-specific IL-10-producing CD8+ T-cell subset with immunomodulatory functions during chronic HIV-1 infection.

scientific article published on 29 August 2013

Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects

scientific article published on May 2017

Expansion and diversification of virus-specific T cells following immunization of human immunodeficiency virus type 1 (HIV-1)-infected individuals with a recombinant modified vaccinia virus Ankara/HIV-1 Gag vaccine.

scientific article

Exposure to zidovudine adversely affects mitochondrial turnover in primary T cells

scientific article published on 2 August 2016

HIV is an independent predictor of aortic stiffness

scientific article published on 16 August 2014

HIV-1-Related Cardiovascular Disease Is Associated With Chronic Inflammation, Frequent Pericardial Effusions, and Probable Myocardial Edema

scientific article

HLA class I and KIR genes do not protect against HIV type 1 infection in highly exposed uninfected individuals with hemophilia A.

scientific article

Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses

scientific article

Immunisation with recombinant modified vaccinia virus Ankara expressing HIV-1 gag in HIV-1-infected subjects stimulates broad functional CD4+ T cell responses

scientific article published in October 2006

Impaired IFN-gamma-secreting capacity in mycobacterial antigen-specific CD4 T cells during chronic HIV-1 infection despite long-term HAART.

scientific article

Induction of multifunctional human immunodeficiency virus type 1 (HIV-1)-specific T cells capable of proliferation in healthy subjects by using a prime-boost regimen of DNA- and modified vaccinia virus Ankara-vectored vaccines expressing HIV-1 Gag c

scientific article published on May 2006

Interleukin-10 responses to therapeutic vaccination during highly active antiretroviral therapy and after analytical therapy interruption.

scientific article published in October 2009

Linking genotype to phenotype on beads: high throughput selection of peptides with biological function

scientific article

Long-term follow up of human T-cell responses to conserved HIV-1 regions elicited by DNA/simian adenovirus/MVA vaccine regimens.

scientific article

Novel, in-natural-infection subdominant HIV-1 CD8+ T-cell epitopes revealed in human recipients of conserved-region T-cell vaccines

scientific article

Phase I clinical trial safety of DNA- and modified virus Ankara-vectored human immunodeficiency virus type 1 (HIV-1) vaccines administered alone and in a prime-boost regime to healthy HIV-1-uninfected volunteers

scientific article

Recent advances in understanding and preventing human papillomavirus-related disease

scientific article published on 14 March 2017

Safety and tolerability of conserved region vaccines vectored by plasmid DNA, simian adenovirus and modified vaccinia virus ankara administered to human immunodeficiency virus type 1-uninfected adults in a randomized, single-blind phase I trial.

scientific article

Safety and tolerability of recombinant modified vaccinia virus Ankara expressing an HIV-1 gag/multiepitope immunogen (MVA.HIVA) in HIV-1-infected persons receiving combination antiretroviral therapy

scientific article published on 11 January 2007

T cell cross-reactivity and conformational changes during TCR engagement

scientific article

Therapeutic HPV vaccines

scientific article published on 28 September 2017

Therapeutic immunization for the control of HIV-1: where are we now?

scientific article published on July 2006

Therapeutic immunization strategies for the control of HIV-1.

scientific article

Transient IL-10 receptor blockade can enhance CD8(+) T cell responses to a simian adenovirus-vectored HIV-1 conserved region immunogen

scientific article published in January 2015

Vaccination with a modified vaccinia virus Ankara (MVA)-vectored HIV-1 immunogen induces modest vector-specific T cell responses in human subjects

scientific article published on 16 September 2010

Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.

scientific article published on 31 October 2013

Viral vectors as vaccine platforms: from immunogenicity to impact

scientific article

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