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List of works by Timothy W Phares

A Peptide-Based Checkpoint Immunomodulator Alleviates Immune Dysfunction in Murine Polymicrobial Sepsis

scientific article published on 15 October 2020

A Peptide-Based PD1 Antagonist Enhances T-Cell Priming and Efficacy of a Prophylactic Malaria Vaccine and Promotes Survival in a Lethal Malaria Model

scientific article published on 09 July 2020

A peroxynitrite-dependent pathway is responsible for blood-brain barrier permeability changes during a central nervous system inflammatory response: TNF-alpha is neither necessary nor sufficient

scientific article

Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis

scientific article published on 9 January 2013

Blood-brain barrier changes and cell invasion differ between therapeutic immune clearance of neurotrophic virus and CNS autoimmunity

scholarly article

CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis

scientific article published on 28 December 2011

CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis

scientific article published on 18 January 2016

CXCR3-dependent plasma blast migration to the central nervous system during viral encephalomyelitis

scientific article

Differential expression of growth factors at the cellular level in virus-infected brain

scientific article

Distinct CD4 T-cell effects on primary versus recall CD8 T-cell responses during viral encephalomyelitis

scientific article published on 4 September 2014

Early blood-brain barrier permeability in cerebella of PLSJL mice immunized with myelin basic protein.

scientific article published on 11 April 2008

Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis.

scientific article published on 14 December 2012

Enhanced antiviral T cell function in the absence of B7-H1 is insufficient to prevent persistence but exacerbates axonal bystander damage during viral encephalomyelitis.

scientific article

Factors supporting intrathecal humoral responses following viral encephalomyelitis.

scientific article

Failure to open the blood-brain barrier and deliver immune effectors to central nervous system tissues leads to the lethal outcome of silver-haired bat rabies virus infection

scientific article

Gamma interferon signaling in oligodendrocytes is critical for protection from neurotropic coronavirus infection

scientific article

ICAM-1 upregulation in the spinal cords of PLSJL mice with experimental allergic encephalomyelitis is dependent upon TNF-alpha production triggered by the loss of blood-brain barrier integrity

scientific article published on 01 October 2004

IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability

scientific article

IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis

scientific article published on 06 August 2013

IL-27 limits central nervous system viral clearance by promoting IL-10 and enhances demyelination.

scientific article

Intrathecal humoral immunity to encephalitic RNA viruses.

scientific article published on 15 February 2013

Liposomes containing monophosphoryl lipid A and QS-21 serve as an effective adjuvant for soluble circumsporozoite protein malaria vaccine FMP013.

scientific article published on 05 June 2017

Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics

scientific article published on 06 March 2020

Progression from IgD+ IgM+ to isotype-switched B cells is site specific during coronavirus-induced encephalomyelitis.

scientific article

Regional differences in blood-brain barrier permeability changes and inflammation in the apathogenic clearance of virus from the central nervous system

scientific article published in June 2006

Rhesus macaque and mouse models for down-selecting circumsporozoite protein based malaria vaccines differ significantly in immunogenicity and functional outcomes

scientific article published on 13 March 2017

Role of CD25(+) CD4(+) T cells in acute and persistent coronavirus infection of the central nervous system

scientific article published on 24 September 2013

Shifting hierarchies of interleukin-10-producing T cell populations in the central nervous system during acute and persistent viral encephalomyelitis.

scientific article

Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium

scientific article

Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis

scientific article published on 22 February 2016

Target-dependent B7-H1 regulation contributes to clearance of central nervous system infection and dampens morbidity.

scientific article

The Structure of the Cysteine-Rich Domain of Plasmodium falciparum P113 Identifies the Location of the RH5 Binding Site

scientific article published on 08 September 2020

The production of antibody by invading B cells is required for the clearance of rabies virus from the central nervous system.

scientific article

Therapeutic Immune Clearance of Rabies Virus from the CNS ⬇️

scientific article published on March 1, 2011

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