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List of works by Peggy L. Olive

A pilot study comparing intratumoral oxygenation using the comet assay following 2.5% and 5% carbogen and 100% oxygen

scientific article published on 01 February 2001

A sensitivity to oxidative stress is linked to chromosome 11 but is not due to a difference in single strand DNA breakage or repair ⬇️

scientific article published on October 1, 1993

Acute hypoxia in tumors: implications for modifiers of radiation effects

scientific article published on 01 August 1986

Analysis of DNA damage in individual cells

scientific article

Apoptosis: an indicator of radiosensitivity in vitro ? ⬇️

scientific article published on June 1, 1997

Carbonic anhydrase 9 as an endogenous marker for hypoxic cells in cervical cancer.

scientific article published in December 2001

Cell Cycle-Dependent Expression of Phosphorylated Histone H2AX: Reduced Expression in Unirradiated but not X-Irradiated G1-Phase Cells

scientific article published on June 1, 2003

Cell Fusion Studies to Examine the Mechanism for Etoposide Resistance in Chinese Hamster V79 Spheroids ⬇️

scientific article published on September 15, 1998

Cell killing and DNA damage by etoposide in Chinese hamster V79 monolayers and spheroids: influence of growth kinetics, growth environment and DNA packaging

scientific article

Cell selection from a murine tumour using the fluorescent probe Hoechst 33342

scientific article published on April 1985

Changes in subcellular distribution of topoisomerase IIalpha correlate with etoposide resistance in multicell spheroids and xenograft tumors.

scientific article published in October 2000

Characterization of radiolabeled fluoromisonidazole as a probe for hypoxic cells

scientific article published on 01 August 1987

Comparison between Pulsed-field and Constant-field Gel Electrophoresis for Measurement of DNA Double-strand Breaks in Irradiated Chinese Hamster Ovary Cells ⬇️

scientific article published on 01 November 1991

Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix

scientific article published in March 2006

Comparison between the binding of [3H]misonidazole and AF-2 in Chinese hamster V79 spheroids

scientific article

Comparison between the comet assay and the oxygen microelectrode for measurement of tumor hypoxia

scientific article published on 01 May 1999

Cytotoxicity of RSU 1069 in spheroids and murine tumors

scientific article published on 01 September 1987

Cytotoxicity, Mutagenicity and DNA damage by Hoechst 33342.

scientific article published on February 1982

DNA conformation of Chinese hamster V79 cells and sensitivity to ionizing radiation

scientific article published on 01 July 1986

DNA double-strand breaks measured in individual cells subjected to gel electrophoresis

article by P L Olive et al published 1 September 1991 in Cancer Research

DNA-PK is responsible for enhanced phosphorylation of histone H2AX under hypertonic conditions

scientific article published in September 2005

Detection of DNA Double-strand Breaks through the Cell Cycle after Exposure to X-rays, Bleomycin, Etoposide and125IdUrd ⬇️

scientific article published on October 1, 1993

Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells

scientific article published on May 1990

Detection of hypoxic cells in a murine tumor with the use of the comet assay

scientific article published on 01 May 1992

Detection of subpopulations resistant to DNA-damaging agents in spheroids and murine tumours

scientific article published on April 1997

Development of apoptosis and polyploidy in human lymphoblast cells as a function of position in the cell cycle at the time of irradiation

scientific article published on 01 December 1996

Effect of angiotensin II on intermittent tumour blood flow and acute hypoxia in the murine SCCVII carcinoma

scientific article

Effect of intercellular contact on DNA conformation, radiation-induced DNA damage, and mutation in Chinese hamster V79 cells

scientific article published in January 1985

Effect of vascular marker Hoechst 33342 on tumour perfusion and cardiovascular function in the mouse

scientific article

Effects of lucanthone on Chinese hamster V-79 cells. II. Damage to DNA

scientific article published on 01 November 1980

Endogenous and radiation-induced expression of gammaH2AX in biopsies from patients treated for carcinoma of the uterine cervix

scientific article published on 10 November 2009

Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability.

scientific article published on 30 June 2006

Enhancement of toxicity from N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea in V79 spheroids by a nitrofuran.

scientific article published in October 1987

Etoposide Sensitivity and Topoisomerase II Activity in Chinese Hamster V79 Monolayers and Small Spheroids ⬇️

scientific article published on September 1, 1991

Evidence for intermittent radiobiological hypoxia in experimental tumour systems

scientific article published on 01 January 1989

Explanation for excessive DNA single-strand breaks and endogenous repair foci in pluripotent mouse embryonic stem cells

scientific article

Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks.

scientific article published in August 2003

Expression of phosphorylated histone H2AX in cultured cell lines following exposure to X-rays

scientific article published in May 2003

Factors influencing DNA migration from individual cells subjected to gel electrophoresis

scientific article published on February 1, 1992

Flow cytometry studies of intracellular adriamycin in single cells in vitro

scientific article published on 01 September 1981

Fluorescent nitroheterocycles for identifying hypoxic cells ⬇️

scientific article published on July 1, 1983

Gel electrophoresis of individual cells to quantify hypoxic fraction in human breast cancers

scientific article published on 01 February 1993

Growth of V79 cells as xenograft tumors promotes multicellular resistance but does not increase spontaneous or radiation-induced mutant frequency

scientific article published on December 2005

Heterogeneity in Radiation-Induced DNA Damage and Repair in Tumor and Normal Cells Measured Using the “Comet” Assay

scientific article published on August 1, 2012

Heterogeneity in human tumour hypoxic fraction using the comet assay

scientific article published on July 1996

Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay

scientific article

Higher-Order Chromatin Structure-Dependent Repair of DNA Double-Strand Breaks: Factors Affecting Elution of DNA from Nucleoids

scientific article published on June 1, 1998

Higher-Order Chromatin Structure-Dependent Repair of DNA Double-Strand Breaks: Involvement of the V(D)J Recombination Double-Strand Break Repair Pathway

scientific article published on 01 May 1998

Higher-Order Chromatin Structure-Dependent Repair of DNA Double-Strand Breaks: Modeling the Elution of DNA from Nucleoids

scientific article published on December 1, 1997

Hypertonic saline enhances expression of phosphorylated histone H2AX after irradiation

scientific article

Hypoxic fractions measured in murine tumors and normal tissues using the comet assay

scientific article published on 01 June 1994

Impact of nicotinamide on human tumour hypoxic fraction measured using the comet assay

scientific article published on 01 November 1997

Induction and rejoining of radiation-induced DNA single-strand breaks: “tail moment” as a function of position in the cell cycle ⬇️

scientific article published on October 1, 1993

Intermittent blood flow in a murine tumor: radiobiological effects

scientific article

Kinetics of H2AX phosphorylation after exposure to cisplatin

scientific article

Lack of a correlation between radiosensitivity and DNA double-strand break induction or rejoining in six human tumor cell lines.

scientific article published in July 1994

Local hypoxia is produced at sites of intratumour injection

scientific article published in February 2002

Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1 alpha stabilization: a role for phosphatidylinositol 3'-kinase

scientific article (publication date: August 2002)

Measuring hypoxia in solid tumours--is there a gold standard?

scientific article published in January 2001

Misonidazole binding in SCCVII tumors in relation to the tumor blood supply

scientific article

Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks

scientific article

Multicell spheroid response to drugs predicted with the comet assay ⬇️

scientific article published on December 15, 1997

Mutagen screening with bacteria: Niridazole and nitrofurans ⬇️

scientific article published on February 1, 1975

Nitrofurazone-reducing enzymes in E. coli and their role in drug activation in vivo ⬇️

scientific article published on October 1, 1975

Overnight lysis improves the efficiency of detection of DNA damage in the alkaline comet assay

scientific article published on April 2001

Oxygen and nitroreductase-dependent binding of AF-2 in spheroids and murine tumors

scientific article

Pharmacokinetics, binding and distribution of Hoechst 33342 in spheroids and murine tumours

scientific article

Phosphorylated histone H2AX in relation to cell survival in tumor cells and xenografts exposed to single and fractionated doses of X-rays

scientific article published on 14 August 2006

Phosphorylated histone H2AX in spheroids, tumors, and tissues of mice exposed to etoposide and 3-amino-1,2,4-benzotriazine-1,3-dioxide

scientific article

Phosphorylation of histone H2AX as a measure of radiosensitivity

scientific article published on February 2004

Possible mechanisms for intermittent blood flow in the murine SCCVII carcinoma

scientific article published on 01 July 1991

Potentiation of CCNU toxicity by AF-2 in V79 spheroids: implications for mechanisms of chemosensitization

scientific article

Potentiation of the tumor cytotoxicity of melphalan by vasodilating drugs

scientific article published on 01 May 1989

RPA foci are associated with cell death after irradiation

scientific article

Radiation Response of Connexin43-Transfected Cells in Relation to the “Contact Effect” ⬇️

scientific article published on August 1, 1997

Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines

scientific article

Radiation-Induced DNA Damage in V79 Spheroids and Monolayers

scientific article published on April 1, 1979

Radiation-induced DNA base damage detected in individual aerobic and hypoxic cells with endonuclease III and formamidopyrimidine-glycosylase

scientific article published in May 1999

Radiation-induced DNA unwinding is influenced by cell shape and trypsin

scientific article published on May 1, 1992

Radiation-induced apoptosis measured in TK6 human B lymphoblast cells using the comet assay

scientific article published on 01 October 1993

Radiosensitisation and radioprotection by BSO and WR-2721: the role of oxygenation

scientific article published in October 1989

Radiosensitization by the histone deacetylase inhibitor PCI-24781.

scientific article published on November 2007

Reduced expression of hypoxia-inducible factor-1alpha in perinecrotic regions of solid tumors.

scientific article published on August 2005

Residual gammaH2AX after irradiation of human lymphocytes and monocytes in vitro and its relation to late effects after prostate brachytherapy

scientific article published on 29 September 2007

Residual gammaH2AX foci as an indication of lethal DNA lesions

scientific article

Resistance to DNA denaturation in irradiated Chinese hamster V79 fibroblasts is linked to cell shape

scientific article published on 01 April 1991

Response of fibroblast cultures from ataxia-telangiectasia patients to reactive oxygen species generated during inflammatory reactions

scientific article published on January 1994

Sizing Highly Fragmented DNA in Individual Apoptotic Cells Using the Comet Assay and a DNA Crosslinking Agent ⬇️

scientific article published on November 1, 1995

The comet assay in clinical practice

scientific article published on 01 January 1999

The comet assay: A new method to examine heterogeneity associated with solid tumors ⬇️

scientific article published on 01 January 1998

The range of oxygenation in SiHa tumor xenografts

scientific article published in August 2002

The use of fluorescent probes to identify regions of transient perfusion in murine tumors

scientific article

Use of a carbocyanine dye as a marker of functional vasculature in murine tumours

scientific article

Use of the comet assay for assessment of drug resistance and its modulation in vivo ⬇️

scientific article published on January 1, 1998

gammaH2AX expression in tumors exposed to cisplatin and fractionated irradiation

scientific article published on 28 April 2009

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