Search filters

List of works by Jesper Melchjorsen

Activation and Evasion of Innate Antiviral Immunity by Herpes Simplex Virus

scientific article published on November 5, 2009

Activation of NF-kappa B in virus-infected macrophages is dependent on mitochondrial oxidative stress and intracellular calcium: downstream involvement of the kinases TGF-beta-activated kinase 1, mitogen-activated kinase/extracellular signal-regulat

scientific article published on June 2003

Activation of innate defense against a paramyxovirus is mediated by RIG-I and TLR7 and TLR8 in a cell-type-specific manner

scientific article

Administration of a Toll-like receptor 9 agonist decreases the proviral reservoir in virologically suppressed HIV-infected patients

scientific article

Antiviral and immunological effects of tenofovir microbicide in vaginal herpes simplex virus 2 infection.

scientific article published on 25 September 2012

Characterization of HIV-1 infection and innate sensing in different types of primary human monocyte-derived macrophages

scientific article published on 28 January 2013

Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation

scientific article published on 31 January 2013

Correction for Jensen et al., Timing of Toll-Like Receptor 9 Agonist Administration in Pneumococcal Vaccination Impacts Both Humoral and Cellular Immune Responses as Well as Nasopharyngeal Colonization in Mice.

scientific article published in September 2014

Cytosolic RNA recognition pathway activates 14-3-3 protein mediated signaling and caspase-dependent disruption of cytokeratin network in human keratinocytes.

scientific article

Differential regulation of the OASL and OAS1 genes in response to viral infections

scientific article

Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways

scientific article published on 25 August 2010

Endotoxemia is associated with altered innate and adaptive immune responses in untreated HIV-1 infected individuals

scientific article

Evaluation of cardiovascular biomarkers in HIV-infected patients switching to abacavir or tenofovir based therapy

scientific article

Expression and function of chemokines during viral infections: from molecular mechanisms to in vivo function

scientific article

Expression of genes for cytokines and cytokine-related functions in leukocytes infected with Herpes simplex virus: comparison between resistant and susceptible mouse strains

scientific article published in July 2002

Expression of type III interferon (IFN) in the vaginal mucosa is mediated primarily by dendritic cells and displays stronger dependence on NF-kappaB than type I IFNs

scientific article

Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA

scientific article (publication date: 2012)

HSV-1-induced chemokine expression via IFI16-dependent and IFI16-independent pathways in human monocyte-derived macrophages

scientific article published on 14 October 2012

Herpes simplex virus selectively induces expression of the CC chemokine RANTES/CCL5 in macrophages through a mechanism dependent on PKR and ICP0

scientific article

Highly active macromolecular prodrugs inhibit expression of the hepatitis C virus genome in the host cells.

scientific article published on 7 August 2014

Induction of RANTES/CCL5 by herpes simplex virus is regulated by nuclear factor kappa B and interferon regulatory factor 3.

scientific article published in September 2003

Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-kappaB and IRF-3.

scientific article published in May 2006

Induction of humoral and cellular immune responses against the HIV-1 envelope protein using γ-retroviral virus-like particles

scientific article

Innate immune recognition and activation during HIV infection

scientific article

Learning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines

scientific article published on 31 January 2013

Polymers fight HIV: potent (pro)drugs identified through parallel automated synthesis.

scientific article published on 9 May 2014

Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

scientific article published on 23 January 2013

RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: dependence on TRAF2 and TAK1.

scientific article published on 18 February 2009

Sensing herpes: more than toll

scientific article published on October 21, 2011

Suppression of proinflammatory cytokine expression by herpes simplex virus type 1.

scientific article

T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication

scientific article published on 3 January 2014

TLR9-adjuvanted pneumococcal conjugate vaccine induces antibody-independent memory responses in HIV-infected adults

scientific article published on August 2012

Tenofovir selectively regulates production of inflammatory cytokines and shifts the IL-12/IL-10 balance in human primary cells

scientific article published on August 2011

Timing of Toll-like receptor 9 agonist administration in pneumococcal vaccination impacts both humoral and cellular immune responses as well as nasopharyngeal colonization in mice

scientific article

Viral activation of macrophages through TLR-dependent and -independent pathways

scientific article