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List of works by Mariusz Ratajczak

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Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery

scientific article published on 2 February 2006
A population of very small embryonic-like (VSEL) CXCR4(+)SSEA-1(+)Oct-4+ stem cells identified in adult bone marrow

scientific article published in May 2006
Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis

scientific article published on 11 May 2005
Migration of Bone Marrow and Cord Blood Mesenchymal Stem Cells In Vitro Is Regulated by Stromal-Derived Factor-1-CXCR4 and Hepatocyte Growth Factor-c-met Axes and Involves Matrix Metalloproteinases

scientific article published in May 2006
CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion

scientific article published in March 2004
Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer

scientific article published in February 2005
Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner

scientific article published on 15 May 2001
Mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ stem cells, and mononuclear cells expressing early cardiac, muscle, and endothelial markers into peripheral blood in patients with acute myocardial infarction

scientific article published on 8 November 2004
Tumour-derived microvesicles carry several surface determinants and mRNA of tumour cells and transfer some of these determinants to monocytes

scientific article published on 9 November 2005
Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre Myocardial Regeneration by Int

scientific article published on 10 February 2009
STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells

scientific article
Morphological and molecular characterization of novel population of CXCR4+ SSEA-4+ Oct-4+ very small embryonic-like cells purified from human cord blood: preliminary report.

scientific article
Pivotal role of paracrine effects in stem cell therapies in regenerative medicine: can we translate stem cell-secreted paracrine factors and microvesicles into better therapeutic strategies?

scientific article published on 19 December 2011
Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction

scientific article published on 18 November 2004
Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization d

scientific article published in April 2010
Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV.

scientific article published on January 2003
CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion.

scientific article published in October 2002
Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment

scientific article published on November 15, 2001
Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient

scientific article published on 24 August 2004
Expression of functional CXCR4 by muscle satellite cells and secretion of SDF-1 by muscle-derived fibroblasts is associated with the presence of both muscle progenitors in bone marrow and hematopoietic stem/progenitor cells in muscles.

scientific article published on January 2003
Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells

scientific article published in May 2002
Lung cancer secreted microvesicles: underappreciated modulators of microenvironment in expanding tumors

scientific article published on October 2009
Clinical evidence that very small embryonic-like stem cells are mobilized into peripheral blood in patients after stroke

scientific article published on 26 February 2009
S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release

scientific article published on 25 January 2012
Mobilization of bone marrow-derived Oct-4+ SSEA-4+ very small embryonic-like stem cells in patients with acute myocardial infarction

scientific article published on January 2009
In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides

scientific article published on December 1992
Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct4(+) very small embryonic-like stem cells

scientific article published on 30 July 2009
Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1

scientific article (publication date: 15 May 2003)
Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow

scientific article published on 6 November 2003
The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells.

scientific article
Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging

scientific article published on March 1991
A hypothesis for an embryonic origin of pluripotent Oct-4(+) stem cells in adult bone marrow and other tissues

scientific article published in May 2007
Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes

scientific article published on 06 August 2009
Enhancing effect of platelet-derived microvesicles on the invasive potential of breast cancer cells

scientific article published on July 2006
Tissue-specific muscle, neural and liver stem/progenitor cells reside in the bone marrow, respond to an SDF-1 gradient and are mobilized into peripheral blood during stress and tissue injury

scientific article published in February 2004
Both hepatocyte growth factor (HGF) and stromal-derived factor-1 regulate the metastatic behavior of human rhabdomyosarcoma cells, but only HGF enhances their resistance to radiochemotherapy.

scientific article published in November 2003
Transplantation of bone marrow-derived very small embryonic-like stem cells attenuates left ventricular dysfunction and remodeling after myocardial infarction

scientific article published on 17 April 2008
Adult murine bone marrow-derived very small embryonic-like stem cells differentiate into the hematopoietic lineage after coculture over OP9 stromal cells

scientific article published on 27 October 2010
Exosomes: an overview of biogenesis, composition and role in ovarian cancer

scientific article published on 25 January 2014
Bone marrow as a source of circulating CXCR4+ tissue-committed stem cells

scientific article published in February 2005
Evidence that very small embryonic-like stem cells are mobilized into peripheral blood

scientific article published on 29 May 2008
Innate immunity as orchestrator of stem cell mobilization

scientific article published on 12 August 2010
A novel view of the adult bone marrow stem cell hierarchy and stem cell trafficking

scientific article published on December 9, 2014
The role of stromal-derived factor-1--CXCR7 axis in development and cancer

scientific article published on 14 October 2009
Conditioning for hematopoietic transplantation activates the complement cascade and induces a proteolytic environment in bone marrow: a novel role for bioactive lipids and soluble C5b-C9 as homing factors

scientific article published on 19 July 2011
Very small embryonic-like stem cells are present in adult murine organs: ImageStream-based morphological analysis and distribution studies

scientific article (publication date: December 2008)
Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas

scientific article published in December 2010
Differential MMP and TIMP production by human marrow and peripheral blood CD34(+) cells in response to chemokines.

scientific article published in November 2000
Leukemia inhibitory factor: a newly identified metastatic factor in rhabdomyosarcomas

scientific article published on March 2007
Morphological characterization of very small embryonic-like stem cells (VSELs) by ImageStream system analysis

scientific article published on 20 November 2007

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