List of works by David Julius

21 Determination of aminoacylation isomeric specificity using tRNA terminating in 3′-amino-3′-deoxyadenosine and 2′-amino-2′-deoxyadenosine

scientific article published on January 1, 1979

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

scholarly article

5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system

scientific article

A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain

scientific article published on 22 August 2019

A Nobel for smell

scientific article published in December 2004

A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain

scientific article

A capsaicin-receptor homologue with a high threshold for noxious heat

scientific article

A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain

scientific article published on 16 November 2011

A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity

scientific article published in May 2003

A neuropeptide courier for delta-opioid receptors?

scientific article published in August 2005

A new wave of serotonin receptors

scientific article

A unified nomenclature for the superfamily of TRP cation channels.

scientific article

A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating

scientific article published on May 2008

ATP receptors in sickness, pain and death

scientific article published on April 1996

ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor

scientific article

Acid potentiation of the capsaicin receptor determined by a key extracellular site

scientific article

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

scientific article

Capsaicin receptor in the pain pathway

scientific article

Cellular and Molecular Mechanisms of Pain

scientific article (publication date: October 2009)

Changes in anxiety-related behaviors and hypothalamic-pituitary-adrenal activity in mice lacking the 5-HT-3A receptor

scientific article published on June 2004

Co-localization of endomorphin-2 and substance P in primary afferent nociceptors and effects of injury: a light and electron microscopic study in the rat.

scientific article published in April 2004

Coiled coils direct assembly of a cold-activated TRP channel

scientific article

Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli.

scientific article published on 19 September 2011

Does long-acting injectable neuroleptic protect against tardive dyskinesia?

scientific article published on 01 October 1982

Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation

scientific article

Editorial overview: molecular biology of sensation

scientific article published on 21 July 2015

Effects of 5-HT1c-receptor expression on cell proliferation control in hamster fibroblasts: Serotonin fails to induce a transformed phenotype ⬇️

scientific article published on June 1, 1992

Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways.

scientific article published on 21 June 2017

Erratum: Structure of the TRPA1 ion channel suggests regulatory mechanisms

scientific article published in Nature

Evolution of thermal response properties in a cold-activated TRP channel

scientific article

Expression cloning of an ATP receptor from mouse neuroblastoma cells

scientific article

Expression of a serotonin-gated ion channel in embryonic neural and nonneural tissues

scientific article

Fire in the hole: pore dilation of the capsaicin receptor TRPV1.

scientific article published in May 2008

From peppers to peppermints: natural products as probes of the pain pathway

scientific article published on January 2005

Functional expression of the 5-HT1c receptor in neuronal and nonneuronal cells

scientific article

Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats

scientific article

Home for an orphan endorphin

scientific article published in Nature

Identification of a cold receptor reveals a general role for TRP channels in thermosensation

scientific journal article

Identification of the platelet ADP receptor targeted by antithrombotic drugs

scientific article

Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat.

scientific article published in March 2004

International Union of Pharmacology. XLIII. Compendium of voltage-gated ion channels: transient receptor potential channels.

scientific article published on December 2003

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels

scientific article

Irritant-evoked activation and calcium modulation of the TRPA1 receptor

scientific article published on 08 July 2020

Isomeric specificity of aminoacylation of wheat germ transfer ribonucleic acid and the specificity of interaction of elongation factor Tu with aminoacyl transfer ribonucleic acid ⬇️

scientific article published on February 20, 1979

Lessons from peppers and peppermint: the molecular logic of thermosensation

scientific article

Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release

scientific article published on 6 March 2017

Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A-/-, 5-HT1B-/-, 5-HT2A-/-, 5-HT3A-/- and 5-HTT-/- knock-out male mice

scientific article published on 23 January 2007

Membrane mimetic systems in CryoEM: keeping membrane proteins in their native environment

scientific article published on 03 July 2019

Molecular basis for species-specific sensitivity to "hot" chili peppers

scientific article published in February 2002

Molecular basis of ancestral vertebrate electroreception

scientific article published on 6 March 2017

Molecular basis of infrared detection by snakes

scientific article

Molecular biology of pituitary development and disease

scientific article published on January 1996

Molecular biology of serotonin receptors

scientific article published on 01 January 1991

Molecular characterization of a functional cDNA encoding the serotonin 1c receptor

scientific article

Molecular tuning of electroreception in sharks and skates

scientific article published in Nature

Multiple unbiased prospective screens identify TRP channels and their conserved gating elements

scientific article published on November 2008

Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1

scientific journal article

NIDA'S Naltrexone Research Program

scientific article published on September 1, 1976

Nervous system distribution of the serotonin 5-HT3 receptor mRNA.

scientific article

Neuroanatomical evidence for segregation of nerve fibers conveying light touch and pain sensation in Eimer's organ of the mole

scholarly article

Neuroendocrine cells initiate protective upper airway reflexes

scientific article published on 18 April 2024

Neuronal expression of the 5HT3 serotonin receptor gene requires nuclear factor 1 complexes.

scientific article published on August 1998

New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor ⬇️

scientific article published on October 6, 1994

Pharmacology of the Nav1.1 domain IV voltage sensor reveals coupling between inactivation gating processes

scientific article published on 12 June 2017

Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel

scientific article

Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels

scientific article

Pungent products from garlic activate the sensory ion channel TRPA1

scientific article

Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons

scientific article

Receptor-targeting mechanisms of pain-causing toxins: How ow?

scientific article

Restriction of transient receptor potential vanilloid-1 to the peptidergic subset of primary afferent neurons follows its developmental downregulation in nonpeptidergic neurons

scientific article published on July 2011

Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain.

scientific article published in March 2005

Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain

scientific journal article

Sense and specificity: a molecular identity for nociceptors

scientific article

Sensory systems

Serotonin receptor 1c gene assigned to X chromosome in human (band q24) and mouse (bands D-F4)

scientific article (publication date: December 1992)

Serotonin receptor knockouts: a moody subject

scientific article

Signaling by extracellular nucleotides

scientific article published on January 1996

Signaling by sensory receptors

scientific article

Single particle electron cryo-microscopy of a mammalian ion channel

scientific article

Spider toxins activate the capsaicin receptor to produce inflammatory pain.

scientific article

Structural insight into TRPV5 channel function and modulation

scientific article published on 11 April 2019

Structural insights into TRPM8 inhibition and desensitization

scientific article

Structure of the TRPA1 ion channel suggests regulatory mechanisms

scientific article

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

scientific article published on 5 December 2013

Structure of the human TRPM4 ion channel in a lipid nanodisc

scientific article

Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

scientific article

TRP channel activation by reversible covalent modification

scientific article

TRP channel structural biology: new roles for an old fold

scientific article

TRP channels and pain

scientific article

TRPA1 mediates formalin-induced pain

scientific article

TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents

scientific journal article

TRPV1 channels are intrinsically heat sensitive and negatively regulated by phosphoinositide lipids

scientific article published on February 2013

TRPV1 structures in distinct conformations reveal activation mechanisms

scientific article

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

scientific journal article

The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. ⬇️

scientific article published in February 2002

The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors

scientific article

The P2Y12 receptor regulates microglial activation by extracellular nucleotides

scientific journal article

The anandamide transport inhibitor AM404 activates vanilloid receptors.

scientific article

The capsaicin receptor: a heat-activated ion channel in the pain pathway

scientific article

The cloned capsaicin receptor integrates multiple pain-producing stimuli

scientific article (publication date: September 1998)

The menthol receptor TRPM8 is the principal detector of environmental cold

scientific journal article

The serotonin receptor subtype 2 locus HTR2 is on human chromosome 13 near genes for esterase D and retinoblastoma-1 and on mouse chromosome 14.

scientific article

The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel

scientific article published on September 2004

The vanilloid receptor: a molecular gateway to the pain pathway

scientific article

Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch

scientific article published on 21 November 2018

Toward better pain control.

scientific article

Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells

scientific article

Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors

scientific article published on August 1999

Uropathic observations in mice expressing a constitutively active point mutation in the 5-HT3A receptor subunit.

scientific article

Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

scientific article

X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel

scientific article

Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function

scientific article

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