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List of works by Evgueni L Saenko

A novel mechanism of factor VIII protection by von Willebrand factor from activated protein C-catalyzed inactivation

scientific article published on 01 June 2002

Anticoagulant effects of a synthetic peptide containing residues Thr-2253-Gln-2270 within factor VIII C2 domain that selectively inhibits factor Xa-catalysed factor VIII activation

scientific article published on 01 March 2002

Catalytic IgG from patients with hemophilia A inactivate therapeutic factor VIII.

scientific article published in July 2006

Coagulation pathways in atherothrombosis

scientific article

Development and applications of surface plasmon resonance-based von Willebrand factor-collagen binding assay

scientific article published in March 2002

Development of a peptidomimetic ligand for efficient isolation and purification of factor VIII via affinity chromatography

scientific article published on 11 August 2007

Development of a small molecule peptidomimetic affinity ligand for efficient purification of the large protein factor VIII.

scientific article published in January 2009

Development of improved factor VIII molecules and new gene transfer approaches for hemophilia A.

scientific article

Editorial: Critical need for pediatric hematologists to specialize in hemostasis and thrombosis ⬇️

scientific article published on 01 September 2010

Effect of factor VIII on tissue factor-initiated spatial clot growth

scientific article published in February 2003

Epitope mapping of polyclonal clotting factor VIII-inhibitory antibodies using phage display

scientific article published in March 2004

Expression of factor VIII in recombinant and transgenic systems

scientific article

Factor VIII - novel insights into form and function

scientific article

Factor VIII bypasses CD91/LRP for endocytosis by dendritic cells leading to T-cell activation.

scientific article published in January 2008

Factor VIIIa regulates substrate delivery to the intrinsic factor X-activating complex

scientific article published in January 2006

Failure of immunocompetitive capillary electrophoresis assay to detect disease-specific prion protein in buffy coat from humans and chimpanzees with Creutzfeldt-Jakob disease

scientific article published in March 2003

Gene therapy for hemophilia A. Friend or foe?

scientific article

Hemophilia A mutations within the factor VIII A2-A3 subunit interface destabilize factor VIIIa and cause one-stage/two-stage activity discrepancy

scientific article published on 01 November 2002

Hemophilia A--from basic science to clinical practice

scientific article

High-throughput optimization of protein expression in the baculovirus system based on determination of relative expression efficiency of viral stocks

scientific article

Human factor VIII inhibitor alloantibodies with a C2 epitope inhibit factor Xa-catalyzed factor VIII activation: a new anti-factor VIII inhibitory mechanism

scientific article published on 01 March 2002

Identification of a plasmin-interactive site within the A2 domain of the factor VIII heavy chain

scientific article published on 14 February 2008

Identification of a protein S-interactive site within the A2 domain of the factor VIII heavy chain

scientific article published in October 2009

Identification of a thrombin-interactive site within the FVIII A2 domain that is responsible for the cleavage at Arg372.

scientific article

Identification of coagulation factor VIII A2 domain residues forming the binding epitope for low-density lipoprotein receptor-related protein.

scientific article published in February 2006

Identification of plasmin-interactive sites in the light chain of factor VIII responsible for proteolytic cleavage at Lys36.

scientific article published on 6 January 2009

Inhibitors in hemophilia A: advances in elucidation of inhibitory mechanisms and in inhibitor management with bypassing agents

scientific article

Inhibitors in hemophilia A: mechanisms of inhibition, management and perspectives

scientific article published on March 2004

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509

scientific article

Intrinsic pathway of blood coagulation contributes to thrombogenicity of atherosclerotic plaque

scientific article published in June 2002

Kinetics of Factor X activation by the membrane-bound complex of Factor IXa and Factor VIIIa

scientific article published on August 2004

Localization of the low-density lipoprotein receptor-related protein regions involved in binding to the A2 domain of coagulation factor VIII

scientific article published on 01 December 2007

Low Density Lipoproteins Interact With Acidic Fibroblast Growth Factor and Modify Its Function ⬇️

scientific article published on 06 March 2003

Mechanisms of action of recombinant activated factor VII in the context of tissue factor concentration and distribution

scientific article

Molecular basis for different ability of low-density and high-density lipoproteins to support activity of the intrinsic Xase complex

scientific article published in January 2002

Protein S down-regulates factor Xase activity independent of activated protein C: specific binding of factor VIII(a) to protein S inhibits interactions with factor IXa.

scientific article published on 28 August 2008

Role of the B domain in proteolytic inactivation of activated coagulation factor VIII by activated protein C and activated factor X.

scientific article published in July 2006

Spatial propagation and localization of blood coagulation are regulated by intrinsic and protein C pathways, respectively

scientific article

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor

scientific article

The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII

scientific article

Treating haemophilia A with recombinant blood factors: a comparison

scientific article published on May 2004

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