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List of works by Natasha Sienkiewicz

Characterisation of a Putative Glutamate 5- Kinase from Leishmania donovani

scientific article

Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes

scientific article published on July 2008

Development and validation of a cytochrome c-coupled assay for pteridine reductase 1 and dihydrofolate reductase

scientific article

Dissecting the metabolic roles of pteridine reductase 1 in Trypanosoma brucei and Leishmania major

scientific article published on 14 January 2011

Structure and reactivity of Trypanosoma brucei pteridine reductase: inhibition by the archetypal antifolate methotrexate

scientific article published on September 2006

The Role of Folate Transport in Antifolate Drug Action in Trypanosoma brucei

scientific article

Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy

scientific article published on 9 September 2013

Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase

scientific article

Trypanosoma brucei pteridine reductase 1 is essential for survival in vitro and for virulence in mice

scientific article

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