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List of works by Daniel Spinks

Chemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasis

scientific article

Design, synthesis and biological evaluation of Trypanosoma brucei trypanothione synthetase inhibitors

scientific article

Design, synthesis and biological evaluation of novel inhibitors of Trypanosoma brucei pteridine reductase 1.

scientific article

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

scientific article

Discovery of a Novel Class of Orally Active Trypanocidal N -Myristoyltransferase Inhibitors

scientific article

Dissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methods

scientific article

Identification and optimisation of a series of 8-hydroxy naphthyridines with potent in vitro antileishmanial activity: Initial SAR and assessment of in vivo activity

scientific article published on 14 July 2020

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

scientific article published on 20 December 2018

Investigation of trypanothione reductase as a drug target in Trypanosoma brucei

scientific article

One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening

scientific article

Optimisation of the anti-Trypanosoma brucei activity of the opioid agonist U50488

scientific article

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

scientific article published on 08 April 2019

Screening a protein kinase inhibitor library against Plasmodium falciparum

scientific article published on 7 November 2017

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