Search filters

List of works by Hideki Sakai

An approach to the research on ion and water properties in the interphase between the plasma membrane and bulk extracellular solution.

scientific article published on 17 February 2017

Association of paracellin-1 with ZO-1 augments the reabsorption of divalent cations in renal epithelial cells

scientific journal article

Bimodal effect of alkalization on the polycystin transient receptor potential channel, PKD2L1

scientific article published on February 22, 2011

Cellular Physiology of Channels and Transporters in Gastrointestinal Tracts

scientific article published on 01 January 2011

Clathrin-dependent endocytosis of claudin-2 by DFYSP peptide causes lysosomal damage in lung adenocarcinoma A549 cells

scientific article published on 8 July 2015

Claudin-16 is directly phosphorylated by protein kinase A independently of a vasodilator-stimulated phosphoprotein-mediated pathway

scientific article published on January 2008

Crosstalk between Na+,K+-ATPase and a volume-regulated anion channel in membrane microdomains of human cancer cells

scientific article published on 13 September 2018

Cyclic AMP-dependent Cl- secretion induced by thromboxane A2 in isolated human colon.

scientific article

E3040 sulphate, a novel thromboxane synthase inhibitor, blocks the Cl- secretion induced by platelet-activating factor in isolated rat colon

scientific journal article

Elevation of sensitivity to anticancer agents of human lung adenocarcinoma A549 cells by knockdown of claudin-2 expression in monolayer and spheroid culture models

scientific article published on 13 December 2017

Erratum to: An approach to the research on ion and water properties in the interphase between the plasma membrane and bulk extracellular solution.

scientific article

Expression of ATP1AL1, a non-gastric proton pump, in human colorectum

scientific article

Flexible synthesis of poison-frog alkaloids of the 5,8-disubstituted indolizidine-class. II: Synthesis of (-)-209B, (-)-231C, (-)-233D, (-)-235B", (-)-221I, and an epimer of 193E and pharmacological effects at neuronal nicotinic acetylcholine recept

scientific article

Frontier of ion pump research

scientific article published in February 2010

Function of K+-Cl- Cotransporters in the Acid Secretory Mechanism of Gastric Parietal Cells

scientific article published on January 1, 2011

Functional association between K+-Cl- cotransporter-4 and H+,K+-ATPase in the apical canalicular membrane of gastric parietal cells

scientific article published on 4 November 2008

Functional consequences of various leucine mutations in the M3/M4 loop of the Na+,K +-ATPase alpha-Subunit

scientific article published on 23 January 2008

Functional coupling of chloride-proton exchanger ClC-5 to gastric H+,K+-ATPase

scientific article published on 15 January 2014

Gating modulation by heat of the polycystin transient receptor potential channel PKD2L1 (TRPP3)

scientific article published on 16 January 2014

Genetic networks responsive to sodium butyrate in colonic epithelial cells.

scientific article published on 27 April 2006

Hyperosmolarity-induced up-regulation of claudin-4 mediated by NADPH oxidase-dependent H2O2 production and Sp1/c-Jun cooperation

scientific article published on 29 June 2013

Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells

scientific article published on 12 October 2016

Impaired actin filaments decrease cisplatin sensitivity via dysfunction of volume-sensitive Cl- channels in human epidermoid carcinoma cells

scientific article published on 05 May 2020

Increase in ouabain-sensitive K+-ATPase activity in hepatocellular carcinoma by overexpression of Na+, K+-ATPase alpha 3-isoform

scientific article published on 03 May 2010

Inhibition of Gastric H+,K+-ATPase Activity in Vitro by Dissolution Media of Original Brand-Name and Generic Tablets of Lansoprazole, a Proton Pump Inhibitor

scientific article published on 01 January 2018

Inhibition of P-type ATPases by [(dihydroindenyl)oxy]acetic acid (DIOA), a K+ -Cl- cotransporter inhibitor

scientific article published on 19 January 2007

Inhibition of ecto-ATPase activity by curcumin in hepatocellular carcinoma HepG2 cells

scientific article published on September 20, 2011

Inhibition of gastric H+,K+-ATPase by 4-(2-butyl-6,7-dichloro-2-cyclopentylindan-1-on-5-yl)oxybutyric acid (DCPIB), an inhibitor of volume-regulated anion channel

scientific article published on 13 August 2015

Inhibition of small-conductance Cl- channels by the interleukin-1beta-stimulated production of superoxide in rabbit gastric parietal cells

scientific article

Involvement of aquaporin-5 in differentiation of human gastric cancer cells

scientific article published on 14 January 2009

Involvement of the H3O+-Lys-164 -Gln-161-Glu-345 charge transfer pathway in proton transport of gastric H+,K+-ATPase

scientific article published on 09 April 2008

Is the ClC-2 chloride channel involved in the Cl- secretory mechanism of gastric parietal cells?

scientific article

K+-Cl- Cotransporter-3a Up-regulates Na+,K+-ATPase in Lipid Rafts of Gastric Luminal Parietal Cells

scientific journal article

L-type amino acid transporter-1 expressed in human astrocytomas, U343MGa

scientific article published on March 2007

Leukotrienes-mediated effects of water extracts from Sargassum horneri, a marine brown alga, on Cl- absorption in isolated rat colon

scientific article published in February 2004

Modulation of H(+),K(+)-ATPase activity by the molecular chaperone ERp57 highly expressed in gastric parietal cells

scientific article

Molecular and pharmacological properties of inwardly rectifying K+ channels of human lung cancer cells

scientific article published on January 2002

Molecular mechanisms of H(+) and Cl(-) secretion in gastric parietal cells

scientific article published on 01 August 2011

Nitric oxide-induced Cl- secretion in isolated rat colon is mediated by the release of thromboxane A2.

scientific article published in August 2002

Non-morphogenic effect of Sonic Hedgehog on gastric H+,K+-ATPase activity

scientific article published on 21 August 2019

Overexpression of heat shock protein 70 restores the structural stability and functional defects of temperature-sensitive mutant of large T antigen at nonpermissive temperature.

scientific article published on January 2006

Pathophysiological properties of CLIC3 chloride channel in human gastric cancer cells

scientific article published on 17 February 2020

Positive regulation of the enzymatic activity of gastric H(+),K(+)-ATPase by sialylation of its β-subunit.

scientific article

Proton-Potassium (H(+)/K(+)) ATPases: Properties and Roles in Health and Diseases

scientific article published on 01 January 2016

Role of cholesterol in functional association between K+–Cl− cotransporter-3a and Na+,K+-ATPase

scientific article published on June 23, 2012

Synthesis of poison-frog alkaloids 233A, 235U, and 251AA and their inhibitory effects on neuronal nicotinic acetylcholine receptors

scientific article published on 26 August 2007

TMEM16F is a component of a Ca2+-activated Cl− channel but not a volume-sensitive outwardly rectifying Cl− channel

scientific article published on February 20, 2013

TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.

scientific article

The NH2-terminus of K+-Cl− cotransporter 3a is essential for up-regulation of Na+,K+-ATPase activity

scientific article published on August 5, 2010

The Relationship Between Actin Cytoskeleton and Membrane Transporters in Cisplatin Resistance of Cancer Cells

scientific article published on 27 October 2020

The asparagine 533 residue in the outer pore loop region of the mouse PKD2L1 channel is essential for its voltage-dependent inactivation

scientific article published on 14 August 2017

The natural flavonoid myricetin inhibits gastric H+, K+-ATPase.

scientific article published on 20 December 2017

Tight junctional localization of claudin-16 is regulated by syntaxin 8 in renal tubular epithelial cells

scientific article

Up-regulation of Kv7.1 channels in thromboxane A2-induced colonic cancer cell proliferation

scientific article published on September 2013

Up-regulation of Na(+),K(+)-ATPase alpha 3-isoform and down-regulation of the alpha1-isoform in human colorectal cancer

scientific article published on April 2004

Upregulation of thromboxane synthase in human colorectal carcinoma and the cancer cell proliferation by thromboxane A2.

scientific article

Volume-sensitive outwardly rectifying Cl(-) channels contribute to butyrate-triggered apoptosis of murine colonic epithelial MCE301 cells.

scientific article

[Cancer cell-specific functional relation between Na+,K+-ATPase and volume-regulated anion channel]

scientific article published on 01 January 2019

[Functional relationship between K(+)-Cl(-) cotransporters and P-type ATPases in gastric parietal cells].

scientific article

[Negative regulation of gastric proton pump by desialylation suggested by fluorescent imaging with the sialic acid-specific nanoprobe]

scientific article published on 01 January 2019