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List of works by Hideki Sakai

A Mini-Review of Reactive Oxygen Species in Urological Cancer: Correlation with NADPH Oxidases, Angiogenesis, and Apoptosis

scientific article published on 22 October 2017

A Review of Oxidative Stress and Urinary Dysfunction Caused by Bladder Outlet Obstruction and Treatments Using Antioxidants.

scientific article

A case of metastatic tumor of spermatic cord from ascending colon carcinoma

scientific article published in September 2006

A case report of bilateral spermatocytic seminoma

scientific article

A pilot study to assess the safety and usefulness of combined transurethral endoscopic mucosal resection and en-bloc resection for non-muscle invasive bladder cancer

scientific article published on 24 June 2019

Analysis of mRNA expression for steroidogenic enzymes in the remaining adrenal cortices attached to adrenocortical adenomas.

scientific article published in June 2008

Analysis of numerical chromosomal aberrations in adrenal cortical neoplasms by fluorescence in situ hybridization

scientific article published on 01 October 2002

Analysis of unilateral adrenal hyperplasia with primary aldosteronism from the aspect of messenger ribonucleic acid expression for steroidogenic enzymes: a comparative study with adrenal cortices adhering to aldosterone-producing adenoma

scientific article

Anti-Cancer Effects of Green Tea Polyphenols Against Prostate Cancer

article by Yasuyoshi Miyata et al published 7 January 2019 in Molecules

Anti-Cancer and Protective Effects of Royal Jelly for Therapy-Induced Toxicities in Malignancies

article

Anticancer Effects of Green Tea and the Underlying Molecular Mechanisms in Bladder Cancer

scientific article published on 10 August 2018

CD105 is a more appropriate marker for evaluating angiogenesis in urothelial cancer of the upper urinary tract than CD31 or CD34.

scientific article published on 25 August 2013

Changes in Angiotensin II Type 1 Receptor Expression in the Rat Bladder by Bladder Outlet Obstruction

scientific article published on July 4, 2012

Changes in Lymphangiogenesis and Vascular Endothelial Growth Factor Expression by Neo-Adjuvant Hormonal Therapy in Prostate Cancer Patients

scientific article published on 16 August 2016

Clinical evaluation of ureteral stenting for managing extrinsic ureteral obstruction due to gynecological and gastrointestinal cancer

scientific article

Clinical significance and predictive value of prostaglandin E2 receptors (EPR) 1 - 4 in patients with renal cell carcinoma

scientific article published on 01 February 2011

Clinical significance and prognostic value of S100A4 and matrix metalloproteinase-14 in patients with organ-confined bladder cancer

scientific article

Combined adrenal adenoma and myelolipoma in a patient with Cushing's syndrome: case report and review of the literature

scientific article published on June 2004

Comparison Between a Combined Transrectal and Transperineal Approach and a Transrectal Approach for Prostate Rebiopsy

scientific article published in September 2016

Composite pheochromocytoma of the adrenal gland: a case series

scientific article published on 24 June 2015

Correction: Oral Intake of Royal Jelly Has Protective Effects against Tyrosine Kinase Inhibitor-Induced Toxicity in Patients with Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled Trial. Medicines, 2019, 6, 2

scientific article published on 19 November 2020

Correlation study showing no concordance between EPAS-1/HIF-2alpha mRNA and protein expression in transitional cellcancer of the bladder

scientific article published on 01 April 2003

Daily salt intake is an independent risk factor for pollakiuria and nocturia

scientific article published on 14 March 2017

De novo minimal change disease after ABO‐incompatible kidney transplantation

scientific article published on 01 July 2012

Determination of Gemcitabine in Plasma of Bladder Cancer Patients by Hydrophilic Interaction Chromatography with Ultraviolet Detection

scientific article published on 25 May 2020

Diagnostic Impacts of Clinical Laboratory Based p2PSA Indexes on any Grade, Gleason Grade Group 2 or Greater, or 3 or Greater Prostate Cancer and Prostate Specific Antigen below 10 ng/ml

scientific article published on 20 August 2019

E1AF expression is associated with extra-prostatic growth and matrix metalloproteinase-7 expression in prostate cancer

scientific article published on 01 November 2009

EGFR signaling pathway negatively regulates PSA expression and secretion via the PI3K-Akt pathway in LNCaP prostate cancer cells

scientific article published on 2 February 2006

Editorial Comment from Dr Miyata and Dr Sakai to Impact of multimodal treatment on prognosis for patients with metastatic upper urinary tract urothelial cancer: Subanalysis of the multi-institutional nationwide case series study of the Japanese Urol

scientific article published on 02 February 2016

Editorial Comment from Dr Miyata and Dr Sakai to Sulfoquinovosylacylpropanediol is a novel potent radiosensitizer in prostate cancer

scientific article published on 23 April 2015

Editorial Comment from Dr Miyata et al. to Impact of serum sodium concentration on survival outcomes in patients with invasive bladder cancer without metastasis treated by cystectomy

scientific article published on 22 January 2019

Editorial Comment to Nutrient intake and urinary incontinence in Korean women: A propensity score-matched analysis from the Korea National Health and Nutrition Examination Survey data

scientific article published on 23 September 2017

Effect of maintenance chemotherapy with gemcitabine and paclitaxel on recurrent squamous cell carcinoma of the bladder: a case report

scientific article published on 01 December 2011

Effect of salt intake reduction on nocturia in patients with excessive salt intake

scientific article published on 01 February 2019

Efficacy and safety of sunitinib alternate day regimen in patients with metastatic renal cell carcinoma in Japan: Comparison with standard 4/2 schedule.

scientific article published on 31 January 2018

Efficacy of Tadalafil Therapy and Changes in Oxidative Stress Levels in Male Patients with Lower Urinary Tract Symptoms and Overactive Bladder

scientific article published on 13 August 2019

Efficacy of mirabegron for overactive bladder with human T cell lymphotropic virus-1 associated myelopathy.

scientific article published on 22 February 2018

Efficacy of naftopidil in patients with overactive bladder associated with benign prostatic hyperplasia: prospective randomized controlled study to compare differences in efficacy between morning and evening medication

scientific article published on January 1, 2011

Efficacy of prosultiamine treatment in patients with human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis: results from an open-label clinical trial

scientific article published on August 15, 2013

Erratum: Oral intake of royal jelly improves anti-cancer effects and suppresses adverse events of molecular targeted therapy by regulating TNF-α and TGF-β in renal cell carcinoma: A preliminary study based on a randomized double-blind clinical trial

scientific article published on 25 September 2020

Establishment of a serum tumor marker for preclinical trials of mouse prostate cancer models

scientific article published on 01 November 2005

Excessive accumulation of visceral fat is associated with lower urinary symptoms including overactive bladder in female patients

scientific article published on 29 December 2020

Expression and function of E prostanoid receptors in urological cancer

scientific article published on February 1, 2013

Expression of Class III Beta-tubulin Predicts Prognosis in Patients with Cisplatin-resistant Bladder Cancer Receiving Paclitaxel-based Second-line Chemotherapy

scientific article published in March 2018

Expression of X-linked inhibitor of apoptosis protein in human prostate cancer specimens with and without neo-adjuvant hormonal therapy

scientific article

Expression of insulin-like growth factor binding protein-3 before and after neoadjuvant hormonal therapy in human prostate cancer tissues: correlation with histopathologic effects and biochemical recurrence

scientific article published in June 2004

Expression of matrix metalloproteinase-10 in non-metastatic prostate cancer: Correlation with an imbalance in cell proliferation and apoptosis

scientific article published on May 1, 2010

Feasibility of simultaneous integrated boost IMRT (SIB-IMRT) for castration-resistant prostate cancer.

scientific article published in August 2014

Feline sarcoma‐related protein expression correlates with malignant aggressiveness and poor prognosis in renal cell carcinoma

scientific article published on April 18, 2013

Four-weekly Low-dose Gemcitabine and Paclitaxel in Patients With Platinum-resistant Urothelial Cancer and Performance Status 2/3

scientific article published on 01 November 2019

Green Tea Polyphenol Induces Changes in Cancer-Related Factors in an Animal Model of Bladder Cancer

scientific article

Gross hematuria and bladder tumor in a patient with advanced thyroid papillary carcinoma

scientific article published on 13 May 2013

Heme oxygenase-1 expression is associated with tumor aggressiveness and outcomes in patients with bladder cancer: a correlation with smoking intensity

scientific article published on 03 July 2014

High Consumption of Green Tea Suppresses Urinary Tract Recurrence of Urothelial Cancer via Down-regulation of Human Antigen-R Expression in Never Smokers

scientific article published on 01 July 2018

High Expression of HuR in Cytoplasm, but Not Nuclei, Is Associated with Malignant Aggressiveness and Prognosis in Bladder Cancer

scientific article published on March 13, 2013

High density of tryptase-positive mast cells in patients with renal cell carcinoma on hemodialysis: correlation with expression of stem cell factor and protease activated receptor-2

scientific article published on December 26, 2011

High expression of Twist is associated with tumor aggressiveness and poor prognosis in patients with renal cell carcinoma

scientific article

Hot flashes during androgen deprivation therapy with luteinizing hormone-releasing hormone agonist combined with steroidal or nonsteroidal antiandrogen for prostate cancer

scientific article published on 26 November 2008

Human antigen R as a predictive marker for response to gemcitabine-based chemotherapy in advanced cisplatin-resistant urothelial cancer

scientific article published on 12 December 2016

Human antigen R is positively associated with malignant aggressiveness via upregulation of cell proliferation, migration, and vascular endothelial growth factors and cyclooxygenase-2 in prostate cancer

scientific article published on 29 April 2016

Immune complexome analysis reveals the specific and frequent presence of immune complex antigens in lung cancer patients: A pilot study.

scientific article published on 29 September 2016

Influence of prior oral ethinylestradiol use on the efficacy of enzalutamide for the treatment of castration-resistant prostate cancer in men.

scientific article

Left atrial metastasis of renal cell carcinoma: a case report and review of the literature

scientific article

Long-term Treatment With Sequential Molecular Targeted Therapy for Xp11.2 Translocation Renal Cell Carcinoma: A Case Report and Review of the Literature

scientific article published on 29 December 2016

Lymphangiogenesis and angiogenesis in conventional renal cell carcinoma: association with vascular endothelial growth factors A to D immunohistochemistry

scientific article published on 04 March 2008

Mechanisms Underlying the Inhibition of Tyrosine Kinase Inhibitor-Induced Anorexia and Fatigue by Royal Jelly in Renal Cell Carcinoma Patients and the Correlation between Macrophage Colony Stimulating Factor and Inflammatory Mediators

scientific article published on 09 October 2020

Met in urological cancers

scientific article

Molecular Mechanisms of the Anti-Cancer Effects of Isothiocyanates from Cruciferous Vegetables in Bladder Cancer

scientific article published on 29 January 2020

Neoadjuvant hormonal therapy for low-risk prostate cancer induces biochemical recurrence after radical prostatectomy via increased lymphangiogenesis-related parameters.

scientific article published on 28 August 2017

Oncological outcomes of hormonal therapy with a gonadotropin-releasing hormone agonist combined with a steroidal or non-steroidal antiandrogen in patients with prostate cancer

Oral Intake of Royal Jelly Has Protective Effects Against Tyrosine Kinase Inhibitor-Induced Toxicity in Patients with Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled Trial

scientific article published on 20 December 2018

Oral intake of royal jelly improves anti-cancer effects and suppresses adverse events of molecular targeted therapy by regulating TNF-α and TGF-β in renal cell carcinoma: A preliminary study based on a randomized double-blind clinical trial

scientific article published on 20 July 2020

Pathologic significance and prognostic value of phosphorylated cortactin expression in patients with sarcomatoid renal cell carcinoma

scientific article published on 21 June 2011

Pathological Characteristics of Periodontal Disease in Patients with Chronic Kidney Disease and Kidney Transplantation

scientific article published on 11 July 2019

Pathological and Pharmacological Roles of Mitochondrial Reactive Oxygen Species in Malignant Neoplasms: Therapies Involving Chemical Compounds, Natural Products, and Photosensitizers

scientific article published on 11 November 2020

Pathological roles of c-Met in bladder cancer: Association with cyclooxygenase-2, heme oxygenase-1, vascular endothelial growth factor-A and programmed death ligand 1

scientific article published on 15 April 2020

Pathological significance and predictive value for biochemical recurrence of c‐Fes expression in prostate cancer

scientific article published on May 11, 2011

Pathological significance and prognostic implications of heme oxygenase 1 expression in non-muscle-invasive bladder cancer: Correlation with cell proliferation, angiogenesis, lymphangiogenesis and expression of VEGFs and COX-2.

scientific article

Pathological significance and prognostic role of microvessel density, evaluated using CD31, CD34, and CD105 in prostate cancer patients after radical prostatectomy with neoadjuvant therapy

scientific article published on 13 October 2014

Pathological significance and prognostic roles of densities of CD57+ cells, CD68+ cells, and mast cells, and their ratios in clear cell renal cell carcinoma

scientific article published on 19 May 2018

Pathological significance and prognostic significance of FES expression in bladder cancer vary according to tumor grade.

scientific article published on 26 September 2017

Periodontal Disease in Patients Receiving Dialysis

scientific article published on 03 August 2019

Pheochromocytoma multisystem crisis treated with emergency surgery: a case report and literature review

scientific article published on 9 December 2015

Prediction of Nonadherence and Renal Prognosis by Pre-Transplantation Serum Phosphate Levels.

scientific article published on 10 May 2019

Predictive Markers for the Recurrence of Nonmuscle Invasive Bladder Cancer Treated with Intravesical Therapy

scientific article

Present Status, Limitations and Future Directions of Treatment Strategies Using Fucoidan-Based Therapies in Bladder Cancer

scientific article published on 15 December 2020

Primary aldosteronism with aldosterone-producing adenoma consisting of pure zona glomerulosa-type cells in a pregnant woman

scientific article published in January 2009

Proliferative activity and genetic changes in adrenal cortical tumors examined by flow cytometry, fluorescence in situ hybridization and immunohistochemistry

scientific article published on 01 February 2005

Prosultiamine for treatment of lower urinary tract dysfunction accompanied by human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis

scientific article published on October 2017

Reconsideration of the clinical and histopathological significance of angiogenesis in prostate cancer: Usefulness and limitations of microvessel density measurement

scientific article

Recovery from life-threatening pelvic organ prolapse in an 80-year-old Japanese woman: a case report

scientific article

Relationship Between Stage-specific Embryonic Antigen-4 and Anti-cancer Effects of Neoadjuvant Hormonal Therapy in Prostate Cancer

scientific article published on 01 October 2020

Relationship between changes in prostate cancer cell proliferation, apoptotic index, and expression of apoptosis-related proteins by neoadjuvant hormonal therapy and duration of such treatment

scientific article published in June 2005

Relationship between prostaglandin E2 receptors and clinicopathologic features in human prostate cancer tissue

scientific article published in December 2006

Renal dysfunction due to hydronephrosis by SAPHO syndrome: a case report

scientific article

Renoprotective effects of telmisartan after unilateral renal ablation in rats

scientific article published on 10 October 2013

Response of recurrent urachal cancer to gemcitabine and cisplatin therapy: a case report and literature review.

scientific article published on June 2011

Response to Re: Reconsideration of the clinical and histopathological significance of angiogenesis in prostate cancer: Usefulness and limitations of microvessel density measurement

scientific article published on 25 October 2015

Safety and efficacy of combination therapy with low-dose gemcitabine, paclitaxel, and sorafenib in patients with cisplatin-resistant urothelial cancer

scientific article

Secondary endocrine therapy with oral estrogen for relapsed prostate cancer

scientific article published in October 2009

Serum insulin-like growth factor binding protein-3/prostate-specific antigen ratio is a useful predictive marker in patients with advanced prostate cancer

scientific article published on 01 February 2003

Smoking-induced changes in cancer-related factors in patients with upper tract urothelial cancer

scientific article

Stability of [-2]Pro-PSA in whole blood and serum: analysis for optimal measurement conditions

Stage-specific embryonic antigen-4 is a histological marker reflecting the malignant behavior of prostate cancer

scientific article published on 26 June 2019

Stromal expression of Fer suppresses tumor progression in renal cell carcinoma and is a predictor of survival

scientific article published on 12 December 2016

Successful laparoscopic resection of a paraganglioma immediately behind the inferior vena cava and bilateral renal veins

scientific article published on 22 June 2019

Successful treatment for retroperitoneal cavernous hemangioma adjacent to the renal hilum via the laparoscopic approach: a case report

scientific article published on 26 February 2014

Susceptibility of muridae cell lines to ecotropic murine leukemia virus and the cationic amino acid transporter 1 viral receptor sequences: implications for evolution of the viral receptor

scientific article published on 28 January 2014

Synaptophysin immunoreactivity in adrenocortical adenomas: a correlation between synaptophysin and CYP17A1 expression

scientific article published on 15 September 2009

TFE3-renal carcinoma in an adult patient: a case with strong expression of phosphorylated hepatocyte growth factor (HGFR)/Met.

scientific article

The Pathological Significance and Prognostic Roles of Thrombospondin-1, and -2, and 4N1K-peptide in Bladder Cancer

scientific article published on 01 May 2019

The efficacy of mirabegron additional therapy for lower urinary tract symptoms after treatment with α1-adrenergic receptor blocker monotherapy: prospective analysis of elderly men.

scientific article

Three cases of brain metastasis from castration-resistant prostate cancer

scientific article published on 04 December 2019

Three cases of nonmetastatic prostate cancer treated successfully with primary intermittent androgen deprivation therapy over 10 years.

scientific article published on 23 February 2017

Thrombospondin-1 in Urological Cancer: Pathological Role, Clinical Significance, and Therapeutic Prospects

scientific article published on 07 June 2013

Thrombospondin-1-derived 4N1K peptide expression is negatively associated with malignant aggressiveness and prognosis in urothelial carcinoma of the upper urinary tract

scientific article published on August 28, 2012

Tumor-associated Stromal Cells Expressing E-prostanoid 2 or 3 Receptors in Prostate Cancer: Correlation With Tumor Aggressiveness and Outcome by Angiogenesis and Lymphangiogenesis

scientific article published on November 11, 2012

Unicentric Castleman's disease with leiomyosarcoma: a rare association

scientific article published on 01 November 2003

Use of low-dose combined therapy with gemcitabine and paclitaxel for advanced urothelial cancer patients with resistance to cisplatin-containing therapy: a retrospective analysis

scientific article published on August 3, 2012

[A Case of Giant Adrenal Endothelial Cyst that was Discovered in Pregnancy and Caused Bleeding Three Years Later]

scientific article published on 01 January 2019

[A case of extramammary Paget's disease with urethral invasion treated by construction of continent urinary diversion based on the Monti principle using the sigmoid colon]

[Clinical analysis of non-clear cell renal cell carcinoma]

[Effectiveness of Cooperative Treatment Using Community Medical Systems and Healthcare Services for Second-Line Therapy in Advanced Urothelial Cancer Patients : Impact on Survival]

scientific article published on 01 April 2020

[Efficacy of periprostatic nerve blockade during ultrasound-guided transrectal 10-core biopsy of the prostate]

scientific article published on 01 November 2005

[Four cases of urinary dysfunction associated with sacral herpes zoster]

[Update of treatment for bladder neoplasm]

scientific article published on 01 January 2011

p38MAPK activation is involved in androgen-independent proliferation of human prostate cancer cells by regulating IL-6 secretion

scientific article published on 20 December 2006