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List of works by Kees Nooter

Activating mutations in c-KIT and PDGFRalpha are exclusively found in gastrointestinal stromal tumors and not in other tumors overexpressing these imatinib mesylate target genes

scientific article

Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill

scientific article

Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib

scientific article published on August 2006

Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps

scientific article published on 9 July 2005

Determination of topotecan in human whole blood and unwashed erythrocytes by high-performance liquid chromatography

scientific article published in January 2002

Does P-glycoprotein play a role in anticancer drug pharmacokinetics?

scientific article published on December 2000

Effect of ABCG2 genotype on the oral bioavailability of topotecan

scientific article published on 11 June 2005

Evaluation of an alternate dosing strategy for cisplatin in patients with extreme body surface area values

scientific article published in April 2006

Functional cloning of drug resistance genes from retroviral cDNA libraries

scientific article

Functional screen for genes responsible for tamoxifen resistance in human breast cancer cells

scientific article published in June 2006

Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

scientific article published on 13 July 2004

Impact of Body-Size Measures on Irinotecan Clearance: Alternative Dosing Recommendations ⬇️

scientific article published on January 1, 2002

Impaired cisplatin influx in an A2780 mutant cell line: evidence for a putative, cis-configuration-specific, platinum influx transporter

scientific article published on 2 August 2006

Inactivation of the Saccharomyces cerevisiae SKY1 gene induces a specific modification of the yeast anticancer drug sensitivity profile accompanied by a mutator phenotype

scientific article published in March 2002

Influence of Cremophor El on the bioavailability of intraperitoneal paclitaxel

scientific article published in April 2002

Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2.

scientific article

Molecular profiling of platinum resistant ovarian cancer.

scientific article published in April 2006

Pharmacokinetic resistance to imatinib mesylate: role of the ABC drug pumps ABCG2 (BCRP) and ABCB1 (MDR1) in the oral bioavailability of imatinib

scientific article published on 22 December 2004

Preclinical evaluation of alternative pharmaceutical delivery vehicles for paclitaxel

scientific article published in August 2002

RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: correlation with chemotherapeutic response.

scientific article

Randomized cross-over evaluation of body-surface area-based dosing versus flat-fixed dosing of paclitaxel

scientific article published in January 2003

Red blood cells: a neglected compartment in topotecan pharmacokinetic analysis

scientific article published in March 2003

Resistance to platinum-containing chemotherapy in testicular germ cell tumors is associated with downregulation of the protein kinase SRPK1.

scientific article published on July 2004

Structural identification and biological activity of 7-methyl-10,11-ethylenedioxy-20(S)-camptothecin, a photodegradant of lurtotecan

scientific article published in March 2002

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