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List of works by Polly J. Bingley

'Insulin autoantibody affinity measurement using a single concentration of unlabelled insulin competitor discriminates risk in relatives of patients with type 1 diabetes

scientific article published on 01 January 2012

-to: Pani MA, Van Autreve J, Van der Auwera BJ, Gorus FK, Badenhoop K (2002) Non-transmitted maternal HLA DQ2 or DQ8 alleles and risk of Type 1 diabetes in offspring: the importance of foetal or post partum exposure to diabetogenic molecules. Diabet

scientific article published on 05 April 2003

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004 ⬇️

article

A comparison of the prevalence of islet autoantibodies in children from two countries with differing incidence of diabetes

scientific article

Absolute risk of childhood-onset type 1 diabetes defined by human leukocyte antigen class II genotype: a population-based study in the United Kingdom

scientific article

An association analysis of the HLA gene region in latent autoimmune diabetes in adults.

scientific article

An increased frequency of NK cell receptor and HLA-C group 1 combinations in early-onset type 1 diabetes ⬇️

scientific article published on September 10, 2011

Anti-BSA antibodies are a major cause of non-specific binding in insulin autoantibody radiobinding assays

scientific article published on 09 September 2010

Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus

scientific article published on 01 July 1994

Antiphospholipid antibody syndrome: a review.

scientific article

Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk

scientific article published on 01 August 2019

Association of intercellular adhesion molecule-1 gene with type 1 diabetes

scientific article published on November 2003

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

scientific article (publication date: 29 May 2003)

Attenuated humoral responses in HLA-A*24-positive individuals at risk of type 1 diabetes.

scientific article published on 30 July 2015

Autoantibodies to IA-2beta improve diabetes risk assessment in high-risk relatives.

scientific article published on 9 January 2008

Autoantibodies to islet antigen-2 are associated with HLA-DRB1*07 and DRB1*09 haplotypes as well as DRB1*04 at onset of type 1 diabetes: the possible role of HLA-DQA in autoimmunity to IA-2.

scientific article published on 27 May 2008

Azide and Tween-20 reduce binding to autoantibody epitopes of islet antigen-2; implications for assay performance and reproducibility

scientific article

Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes

scientific article published on 3 September 2016

Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes

scientific article

Can we prevent IDDM?

scientific article published on 01 April 1994

Capillary whole blood measurement of islet autoantibodies

scientific article published on 01 February 1999

Cerebellar ataxia, peripheral neuropathy, "gluten sensitivity" and anti-neuronal autoantibodies.

scientific article

Children with type-1 diabetes and their unaffected siblings have fewer symptoms of asthma

scientific article published on 01 May 1999

Clinical applications of diabetes antibody testing

scientific article published on 29 October 2009

Combined analysis of IDDM-related autoantibodies in healthy schoolchildren

scientific article published on 01 September 1994

Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives

scientific article published on 01 November 1994

Combined testing of antibody titer and affinity improves insulin autoantibody measurement: Diabetes Antibody Standardization Program

scientific article published on 23 October 2006

Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop

scientific article published on 01 December 1998

Continuing metformin when starting insulin in patients with Type 2 diabetes: a double-blind randomized placebo-controlled trial

scientific article

Coxsackie B virus and postviral fatigue syndrome ⬇️

scientific article published on March 16, 1991

Diabetes Antibody Standardization Program: First Assay Proficiency Evaluation ⬇️

scientific article published on May 1, 2003

Diabetes Antibody Standardization Program: First evaluation of assays for autoantibodies to IA-2β

scientific article

Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2.

scientific article published on 29 March 2008

Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies

scientific article published on 25 September 2010

Diabetes mellitus among young adults in Sri Lanka--role of GAD antibodies in classification and treatment: the Sri Lanka Young Diabetes study

scientific article published on 5 June 2008

Early T-cell defects in pre-type 1 diabetes

scientific article published on January 1, 1992

Early onset of diabetes in the proband is the major determinant of risk in HLA DR3-DQ2/DR4-DQ8 siblings.

scientific article published on 7 November 2013

Early-onset, coexisting autoimmunity and decreased HLA-mediated susceptibility are the characteristics of diabetes in Down syndrome.

scientific article published on 28 December 2012

Eczema and Type 1 diabetes

scientific article published on 01 February 2002

Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial

scientific article published on April 2015

Erratum. Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes. Diabetes 2014;63:3835-3845

scientific article published on September 2015

European Nicotinamide Diabetes Intervention Trial (ENDIT): a randomised controlled trial of intervention before the onset of type 1 diabetes

scientific article published in March 2004

Evaluation of a high-throughput second antibody radiobinding assay for measuring IgA antibodies to human tissue transglutaminase

scientific article published on 01 August 1999

Evidence that HLA class I and II associations with type 1 diabetes, autoantibodies to GAD and autoantibodies to IA-2, are distinct.

scientific article

Family studies of insulin-dependent diabetes: the UK experience

scientific article published on 01 January 1988

GAD autoantibodies and epitope reactivities persist after diagnosis in latent autoimmune diabetes in adults but do not predict disease progression: UKPDS 77

scientific article published on 27 July 2007

Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

scientific article

HLA class II typing of whole genome amplified mouth swab DNA

scientific article published on 01 December 2000

HLA genotyping supports a nonautoimmune etiology in patients diagnosed with diabetes under the age of 6 months

scientific article published on 01 June 2006

Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for national institute of diabetes and digestive and kidney diseases consortia

scientific article

High Familial Risk and Genetic Susceptibility in Early Onset Childhood Diabetes ⬇️

scientific article published on 01 January 2002

Housing subsidies and work incentives in Great Britain

scientific article published on 01 January 2001

Humoral Responses to Islet Antigen-2 and Zinc Transporter 8 Are Attenuated in Patients CarryingHLA-A*24Alleles at the Onset of Type 1 Diabetes ⬇️

scientific article published on February 8, 2013

IGF-secreting tumour treated with a combination of growth hormone and glucocorticoids

scientific article published on 01 May 2006

Identifying hepatic nuclear factor 1alpha mutations in children and young adults with a clinical diagnosis of type 1 diabetes

scientific article

Impact of Age and Antibody Type on Progression From Single to Multiple Autoantibodies in Type 1 Diabetes Relatives

scientific article published on 22 May 2017

Influence of maternal age at delivery and birth order on risk of type 1 diabetes in childhood: prospective population based family study. Bart's-Oxford Family Study Group

scientific article

Insulin resistance and progression to type 1 diabetes in the European Nicotinamide Diabetes Intervention Trial (ENDIT).

scientific article published on 24 October 2007

Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes

scientific article published on 21 November 2019

Is puberty an accelerator of type 1 diabetes in IL6-174CC females?

scientific article published on 01 April 2005

Islet autoantibodies can discriminate maturity-onset diabetes of the young (MODY) from Type 1 diabetes

scientific article published on 01 September 2011

Islet autoantibodies, nationality and gender: a multinational screening study in first-degree relatives of patients with Type I diabetes

scientific article published on 01 February 2002

Islet autoantibody markers in IDDM: risk assessment strategies yielding high sensitivity

scientific article published on July 1995

Islet autoantibody testing: an end to the trials and tribulations?

scientific article published on December 2013

Islet autoimmunity in children with Down's syndrome

scientific article published on 01 November 2006

Latent autoimmune diabetes in adults (LADA) in South Wales: incidence and characterisation

Loss of regular oscillatory insulin secretion in islet cell antibody positive non-diabetic subjects

scientific article published on January 1992

Low interleukin-2 receptor levels in serum of patients with insulin-dependent diabetes

scientific article published on 01 July 1994

Maternal microchimerism in peripheral blood in type 1 diabetes and pancreatic islet beta cell microchimerism.

scholarly article

Measurement of islet cell antibodies in the Type 1 Diabetes Genetics Consortium: efforts to harmonize procedures among the laboratories ⬇️

scientific article published on January 1, 2010

Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes

scientific article published on 28 May 2003

Mortality of South Asian patients with insulin-treated diabetes mellitus in the United Kingdom: a cohort study

scientific article published in August 2004

Nicotinamide and insulin secretion in normal subjects

scientific article

Non-specific binding to protein A Sepharose and protein G Sepharose in insulin autoantibody assays may be reduced by pre-treatment with glycine or ethanolamine

scientific article published on 28 June 2006

Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes

scientific article

Predicting type 1 diabetes using autoantibodies: the latest results from the diabetes autoantibody standardization program

scientific article published on 01 January 2002

Presentation and progress of childhood diabetes mellitus: a prospective population-based study

Presentation and progress of childhood diabetes mellitus: a prospective population-based study. The Bart's-Oxford Study Group

scientific article published on 01 January 1994

Prevention of type 1 diabetes

scientific article published on 02 July 2011

Progression to diabetes in relatives with islet autoantibodies. Is it inevitable?

scientific article published on 01 December 1999

Progression to type 1 diabetes in islet cell antibody-positive relatives in the European Nicotinamide Diabetes Intervention Trial: the role of additional immune, genetic and metabolic markers of risk

scientific article published on 3 March 2006

Proinsulin-specific autoantibodies are relatively infrequent in young offspring with pre-type 1 diabetes

scientific article published on 01 October 2001

Proposed guidelines on screening for risk of type 1 diabetes

scientific article published on 01 February 2001

Quantification of islet-cell antibodies and prediction of insulin-dependent diabetes

scientific article published on January 1990

Rationale and protocol for the After Diabetes Diagnosis REsearch Support System (ADDRESS): an incident and high risk type 1 diabetes UK cohort study.

scientific article

Reactivity to N-Terminally Truncated GAD65(96-585) Identifies GAD Autoantibodies That Are More Closely Associated With Diabetes Progression in Relatives of Patients With Type 1 Diabetes

scientific article published on 22 May 2015

Relationship between islet autoantibody status and the clinical characteristics of children and adults with incident type 1 diabetes in a UK cohort.

scientific article

Restriction fragment length polymorphism analysis of HLA haplotypes in families with type I diabetes mellitus

scientific article published on 01 January 1990

Rising incidence of type 1 diabetes is associated with altered immunophenotype at diagnosis

scientific article published on 7 February 2012

Risk of pediatric celiac disease according to HLA haplotype and country

scientific article

Safety of high-dose nicotinamide: a review

scientific article

Seasonal variation in month of diagnosis in children with type 1 diabetes registered in 23 European centers during 1989-2008: little short-term influence of sunshine hours or average temperature. ⬇️

scientific article published on 15 October 2014

Sera from patients with IDDM and healthy individuals have antibodies to ICA69 on western blots but do not immunoprecipitate liquid phase antigen

scientific article

Slow metabolic deterioration towards diabetes in islet cell antibody positive patients with autoimmune polyendocrine disease

scientific article published on 01 April 1994

Soluble L-selectin levels in type I diabetes mellitus: a surrogate marker for disease activity?

scientific article published on 01 February 2000

Standardization of IVGTT to predict IDDM

scientific article published on October 1, 1992

Strategies to prevent type 1 diabetes

scientific article published on 19 May 2009

Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics

scientific article published on 01 February 2004

Systematic assessment of etiology in adults with a clinical diagnosis of young-onset type 2 diabetes is a successful strategy for identifying maturity-onset diabetes of the young

scientific article

The British Diabetic Association Cohort Study, II: cause-specific mortality in patients with insulin-treated diabetes mellitus

scientific article

The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results

scientific article published on 24 September 2008

The core cysteines, (C909) of islet antigen-2 and (C945) of islet antigen-2β, are crucial to autoantibody binding in type 1 diabetes.

scientific article

The implications of autoantibodies to a single islet antigen in relatives with normal glucose tolerance: development of other autoantibodies and progression to type 1 diabetes

scientific article published on 16 December 2015

The prevalence of insulin autoantibodies at the onset of Type 1 diabetes is higher in males than females during adolescence

scientific article published on 9 September 2003

The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes

scientific article published on 01 November 2004

The role of autoantibodies to zinc transporter 8 in prediction of type 1 diabetes in relatives: lessons from the European Nicotinamide Diabetes Intervention Trial (ENDIT) cohort

scientific article published on 07 December 2011

Three generations of autoimmune diabetes: an extended family study

scientific article published on 30 July 2003

Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989–2013: a multicentre prospective registration study ⬇️

scientific article published on 28 November 2018

Trends in childhood type 1 diabetes incidence in Europe during 1989-2008: evidence of non-uniformity over time in rates of increase

scientific article published on 26 May 2012

Two distinctly HLA-associated contiguous linear epitopes uniquely expressed within the islet antigen 2 molecule are major autoantibody epitopes of the diabetes-specific tyrosine phosphatase-like protein autoantigens

scientific article

Type 1 Diabetes TrialNet: A Multifaceted Approach to Bringing Disease-Modifying Therapy to Clinical Use in Type 1 Diabetes

scientific article published on 01 April 2018

Type 1 diabetes risk assessment: improvement by follow-up measurements in young islet autoantibody-positive relatives

scientific article published on 26 September 2006

Undiagnosed coeliac disease at age seven: population based prospective birth cohort study.

scientific article

Use of Dried Capillary Blood Sampling for Islet Autoantibody Screening in Relatives: A Feasibility Study

scientific article

Use of self-collected capillary blood samples for islet autoantibody screening in relatives: a feasibility and acceptability study

scientific article

Validation of autoantibody assays in type 1 diabetes: workshop programme

scientific article

What is Type 1 Diabetes?

scientific article

Worth the wait: type 1 diabetes prospective birth cohort studies enter adolescence ⬇️

scientific article published on May 20, 2012

Zinc Transporter-8 Autoantibodies Improve Prediction of Type 1 Diabetes in Relatives Positive for the Standard Biochemical Autoantibodies ⬇️

scientific article published on March 23, 2012

[Prevalence of ICA antibodies, anti-GAD and antylA-2 in women with gestational diabetes treated with diet]

scientific article published on 01 January 1999

β-cell specific T-lymphocyte response has a distinct inflammatory phenotype in children with Type 1 diabetes compared with adults

scientific article published on 30 May 2016

β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure

scientific article

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