List of works - Ogyi Park

A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury

scientific article

AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice

scientific journal article

Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis

scientific article

Activation of innate immunity (NK/IFN-gamma) in rat allogeneic liver transplantation: contribution to liver injury and suppression of hepatocyte proliferation

scientific article published on 21 February 2008

Acute and chronic effects of IL-22 on acetaminophen-induced liver injury

scientific article

Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice

scientific article published on 9 May 2014

Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice.

scientific article

Analysis of the Foxp3/scurfin gene in Crohn's disease

scientific article published in June 2005

Anti-inflammatory and anti-apoptotic roles of endothelial cell STAT3 in alcoholic liver injury

scientific article

Antimitochondrial antibodies in acute liver failure: implications for primary biliary cirrhosis

scientific article

Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences

scientific article published on 30 May 2015

Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death

scientific article

Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury

scientific article published on 11 January 2008

Chronic expression of interferon-gamma leads to murine autoimmune cholangitis with a female predominance

scientific article published on 14 May 2016

Chronic plus binge ethanol feeding synergistically induces neutrophil infiltration and liver injury in mice: a critical role for E-selectin

scientific article published on 30 September 2013

Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice

scientific article

Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression

scientific article published on 09 May 2016

Dissociation between liver inflammation and hepatocellular damage induced by carbon tetrachloride in myeloid cell-specific signal transducer and activator of transcription 3 gene knockout mice

scientific article

Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure

scientific article published in 2022

Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride

scientific article published on May 2009

Enhanced Liver Regeneration in IL-10–Deficient Mice after Partial Hepatectomy via Stimulating Inflammatory Response and Activating Hepatocyte STAT3 ⬇️

scientific article published on April 1, 2011

Hepatic Hippo signaling inhibits protumoural microenvironment to suppress hepatocellular carcinoma

scientific article published on 2 September 2017

Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis ⬇️

scientific article published on September 8, 2010

Hepatoprotective versus Oncogenic Functions of STAT3 in Liver Tumorigenesis ⬇️

scientific article published on June 2, 2011

Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis

scientific article

Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1

scientific article published on 18 April 2019

Immunization with a Xenobiotic 6-Bromohexanoate Bovine Serum Albumin Conjugate Induces Antimitochondrial Antibodies ⬇️

scientific article published on May 15, 2003

In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression ⬇️

scientific article published on July 1, 2011

Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization

scientific article published in August 2007

Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10-deficient mice

scientific article

Interferon-lambda (IFN-λ) induces signal transduction and gene expression in human hepatocytes, but not in lymphocytes or monocytes

scientific article published on 20 December 2012

Interleukin-22 Promotes Proliferation of Liver Stem/Progenitor Cells in Mice and Patients With Chronic Hepatitis B Virus Infection ⬇️

scientific article published on April 3, 2012

Interleukin-22 ameliorates cerulein-induced pancreatitis in mice by inhibiting the autophagic pathway

scientific article published on 6 January 2012

Interplay of hepatic and myeloid signal transducer and activator of transcription 3 in facilitating liver regeneration via tempering innate immunity.

scientific article

Invariant NKT cell activation induces neutrophil accumulation and hepatitis: opposite regulation by IL-4 and IFN-γ

scientific article published on 06 August 2013

Is there a relation between Chlamydia infection and primary biliary cirrhosis?

scientific article published on June 2003

Lack of PPARα exacerbates lipopolysaccharide-induced liver toxicity through STAT1 inflammatory signaling and increased oxidative/nitrosative stress ⬇️

scientific article published on January 22, 2011

Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases

scientific article published on September 2009

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

scientific journal article

Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production

scientific article published on 15 August 2009

NKT cells in liver fibrosis: controversies or complexities.

scientific article published on 19 July 2011

Opposing effects of prednisolone treatment on T/NKT cell- and hepatotoxin-mediated hepatitis in mice

scientific article published on 21 January 2014

PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis

scientific article

PEGylated TRAIL ameliorates experimental inflammatory arthritis by regulation of Th17 cells and regulatory T cells

scientific article published on 7 October 2017

Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver

scientific article published in March 2008

Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis

scientific article published on April 2014

Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice

scientific article

Retinoic acid signaling sensitizes hepatic stellate cells to NK cell killing via upregulation of NK cell activating ligand RAE1.

scientific article published on 2 August 2007

STAT1 contributes to dsRNA inhibition of liver regeneration after partial hepatectomy in mice.

scientific article published in October 2006

STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity

scientific article published in December 2006

STAT4 knockout mice are more susceptible to concanavalin A-induced T-cell hepatitis

scientific article

Suppression of innate immunity (natural killer cell/interferon-γ) in the advanced stages of liver fibrosis in mice

scientific article

Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells

scientific article published on 28 December 2015

Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma

scientific article published on 08 March 2019

Tyrosine kinase inhibitor neratinib attenuates liver fibrosis by targeting activated hepatic stellate cells

scientific article published on 08 September 2020

List of works by Ogyi Park

A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury

AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice

Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis

Activation of innate immunity (NK/IFN-gamma) in rat allogeneic liver transplantation: contribution to liver injury and suppression of hepatocyte proliferation

Acute and chronic effects of IL-22 on acetaminophen-induced liver injury

Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice

Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice.

Analysis of the Foxp3/scurfin gene in Crohn's disease

Anti-inflammatory and anti-apoptotic roles of endothelial cell STAT3 in alcoholic liver injury

Antimitochondrial antibodies in acute liver failure: implications for primary biliary cirrhosis

Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences

Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death

Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury

Chronic expression of interferon-gamma leads to murine autoimmune cholangitis with a female predominance

Chronic plus binge ethanol feeding synergistically induces neutrophil infiltration and liver injury in mice: a critical role for E-selectin

Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice

Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression

Dissociation between liver inflammation and hepatocellular damage induced by carbon tetrachloride in myeloid cell-specific signal transducer and activator of transcription 3 gene knockout mice

Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure

Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride

Enhanced Liver Regeneration in IL-10–Deficient Mice after Partial Hepatectomy via Stimulating Inflammatory Response and Activating Hepatocyte STAT3 ⬇️

Hepatic Hippo signaling inhibits protumoural microenvironment to suppress hepatocellular carcinoma

Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis ⬇️

Hepatoprotective versus Oncogenic Functions of STAT3 in Liver Tumorigenesis ⬇️

Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis

Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1

Immunization with a Xenobiotic 6-Bromohexanoate Bovine Serum Albumin Conjugate Induces Antimitochondrial Antibodies ⬇️

In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression ⬇️

Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization

Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10-deficient mice

Interferon-lambda (IFN-λ) induces signal transduction and gene expression in human hepatocytes, but not in lymphocytes or monocytes

Interleukin-22 Promotes Proliferation of Liver Stem/Progenitor Cells in Mice and Patients With Chronic Hepatitis B Virus Infection ⬇️

Interleukin-22 ameliorates cerulein-induced pancreatitis in mice by inhibiting the autophagic pathway

Interplay of hepatic and myeloid signal transducer and activator of transcription 3 in facilitating liver regeneration via tempering innate immunity.

Invariant NKT cell activation induces neutrophil accumulation and hepatitis: opposite regulation by IL-4 and IFN-γ

Is there a relation between Chlamydia infection and primary biliary cirrhosis?

Lack of PPARα exacerbates lipopolysaccharide-induced liver toxicity through STAT1 inflammatory signaling and increased oxidative/nitrosative stress ⬇️

Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production

NKT cells in liver fibrosis: controversies or complexities.

Opposing effects of prednisolone treatment on T/NKT cell- and hepatotoxin-mediated hepatitis in mice

PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis

PEGylated TRAIL ameliorates experimental inflammatory arthritis by regulation of Th17 cells and regulatory T cells

Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver

Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis

Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice

Retinoic acid signaling sensitizes hepatic stellate cells to NK cell killing via upregulation of NK cell activating ligand RAE1.

STAT1 contributes to dsRNA inhibition of liver regeneration after partial hepatectomy in mice.

STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity

STAT4 knockout mice are more susceptible to concanavalin A-induced T-cell hepatitis

Suppression of innate immunity (natural killer cell/interferon-γ) in the advanced stages of liver fibrosis in mice

Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells

Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma

Tyrosine kinase inhibitor neratinib attenuates liver fibrosis by targeting activated hepatic stellate cells