List of works - James S. Wainscoat

5q- syndrome

scientific article published on January 2012

Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies

scientific article published on 13 September 2012

Advances in the 5q- syndrome

scientific article published on 23 August 2010

Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression

scientific article published on October 2009

Gene expression profiles of CD34+ cells in myelodysplastic syndromes: involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype.

scientific article

Gene expression profiling in polycythemia vera using cDNA microarray technology.

scientific article

Gene expression profiling in the myelodysplastic syndromes

scientific article

Gene expression profiling in the myelodysplastic syndromes using cDNA microarray technology

article

Gene expression profiling of CD34+cells in patients with the 5q− syndrome

article

Gene expression profiling of erythroblasts from refractory anaemia with ring sideroblasts (RARS) and effects of G-CSF.

scientific article published on 12 April 2010

Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes

scientific article published on 8 May 2008

Haploinsufficiency of ribosomal proteins and p53 activation in anemia: Diamond-Blackfan anemia and the 5q- syndrome

scientific article published on January 2012

Identification of Gene Expression–Based Prognostic Markers in the Hematopoietic Stem Cells of Patients With Myelodysplastic Syndromes

article

Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the α-thalassemia myelodysplasia syndrome (ATMDS)

article

Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome

scientific article published on 01 April 2010

Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients

scholarly article

Low expression of the putative tumour suppressor gene gravin in chronic myeloid leukaemia, myelodysplastic syndromes and acute myeloid leukaemia.

scientific article

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome

scientific article published on 15 April 2011

Marked downregulation of the granulopoiesis regulator LEF1 is associated with disease progression in the myelodysplastic syndromes

scientific article

Molecular and clinical features of refractory anemia with ringed sideroblasts associated with marked thrombocytosis

scientific article published on 19 August 2009

Mutation patterns of 16 genes in primary and secondary acute myeloid leukemia (AML) with normal cytogenetics

scientific article

Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34⁺ progenitor cells

scientific article

Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes

scientific article published on 05 July 2013

The role of the iron transporter ABCB7 in refractory anemia with ring sideroblasts

scientific article

List of works by James S. Wainscoat

5q- syndrome

Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies

Advances in the 5q- syndrome

Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression

Gene expression profiles of CD34+ cells in myelodysplastic syndromes: involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype.

Gene expression profiling in polycythemia vera using cDNA microarray technology.

Gene expression profiling in the myelodysplastic syndromes

Gene expression profiling in the myelodysplastic syndromes using cDNA microarray technology

Gene expression profiling of CD34+cells in patients with the 5q− syndrome

Gene expression profiling of erythroblasts from refractory anaemia with ring sideroblasts (RARS) and effects of G-CSF.

Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes

Haploinsufficiency of ribosomal proteins and p53 activation in anemia: Diamond-Blackfan anemia and the 5q- syndrome

Identification of Gene Expression–Based Prognostic Markers in the Hematopoietic Stem Cells of Patients With Myelodysplastic Syndromes

Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the α-thalassemia myelodysplasia syndrome (ATMDS)

Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome

Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients

Low expression of the putative tumour suppressor gene gravin in chronic myeloid leukaemia, myelodysplastic syndromes and acute myeloid leukaemia.

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome

Marked downregulation of the granulopoiesis regulator LEF1 is associated with disease progression in the myelodysplastic syndromes

Molecular and clinical features of refractory anemia with ringed sideroblasts associated with marked thrombocytosis

Mutation patterns of 16 genes in primary and secondary acute myeloid leukemia (AML) with normal cytogenetics

Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34⁺ progenitor cells

Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes

The role of the iron transporter ABCB7 in refractory anemia with ring sideroblasts