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List of works by Francisco Borrás-Cuesta

A fusion protein between streptavidin and the endogenous TLR4 ligand EDA targets biotinylated antigens to dendritic cells and induces T cell responses in vivo.

scientific article published on 05 September 2013

A peptide inhibitor of FOXP3 impairs regulatory T cell activity and improves vaccine efficacy in mice.

scientific article

A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine-induced liver damage

scientific article published in February 2003

A synthetic peptide from transforming growth factor beta type III receptor inhibits liver fibrogenesis in rats with carbon tetrachloride liver injury

scientific article published in April 2003

A synthetic peptide from transforming growth factor-beta1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats

scientific article published on 19 November 2008

A synthetic peptide from transforming growth factor-β₁ type III receptor inhibits NADPH oxidase and prevents oxidative stress in the kidney of spontaneously hypertensive rats

scientific article published on 18 March 2013

Abnormal priming of CD4(+) T cells by dendritic cells expressing hepatitis C virus core and E1 proteins.

scientific article

Adjuvant Combination and Antigen Targeting as a Strategy to Induce Polyfunctional and High-Avidity T-Cell Responses against Poorly Immunogenic Tumors

article

B cell epitopes of HIV type 1 p24 capsid protein: a reassessment

scientific article published on 01 April 1996

Blockade of TGF-β 1 signalling inhibits cardiac NADPH oxidase overactivity in hypertensive rats.

scientific article

CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination.

scientific article published on December 2003

CD4-modified synthetic peptides containing phenylalanine inhibit HIV-1 infection in vitro.

scientific article published on February 1994

Carcinoembryonic antigen as a target to induce anti-tumor immune responses.

scientific article published in August 2004

Cellular immunity to hepatitis C virus core protein and the response to interferon in patients with chronic hepatitis C.

scientific article published on September 1998

Characterization of T-cell responses against immunodominant epitopes from hepatitis C virus E2 and NS4a proteins.

scientific article published in January 2006

Characterization of an immunologically conserved epitope from hepatitis C virus E2 glycoprotein recognized by HLA-A2 restricted cytotoxic T lymphocytes

scientific article published on February 2001

Combined immunization with adjuvant molecules poly(I:C) and anti-CD40 plus a tumor antigen has potent prophylactic and therapeutic antitumor effects

scientific article published on 13 June 2007

Detection of anti-hepatitis C virus antibodies by ELISA using synthetic peptides

scientific article published in April 1993

Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a coadministered antigen: the role of nitric oxide

scientific article published in May 1999

Engineered promiscuous T helper peptides for the induction of immune responses

scientific article published on 8 December 2006

Engineering Th determinants for efficient priming of humoral and cytotoxic T cell responses

scientific article published on 01 June 2003

Enhanced T cell responses against hepatitis C virus by ex vivo targeting of adenoviral particles to dendritic cells

scientific article published on 14 May 2011

Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus

scientific article published in May 2005

Enhancement of peptide immunogenicity by insertion of a cathepsin B cleavage site between determinants recognized by B and T cells

scientific article published on 01 May 1993

Enhancing immunogenicity of a CTL epitope from carcinoembryonic antigen by selective amino acid replacements.

scientific article

Fine analysis of immunoreactivity of V3 peptides: antibodies specific for V3 domain of laboratory HIV type 1 strains recognize multiple V3 sequences synthesized from field HIV type 1 isolates

scientific article published in December 1996

Further insights on the inhibition of HIV type 1 infection in vitro by CD4-modified synthetic peptides containing phenylalanine

scientific article published on July 1996

Helper cell-independent antitumor activity of potent CD8(+) T cell epitope peptide vaccines is dependent upon CD40L.

scientific article published on 05 December 2013

Hepatitis C Virus Structural Proteins Impair Dendritic Cell Maturation and Inhibit In Vivo Induction of Cellular Immune Responses

scientific article

Identification and characterization of a T-helper peptide from carcinoembryonic antigen.

scientific article published on April 2004

Identification of HLA-B27-restricted cytotoxic T lymphocyte epitope from carcinoembryonic antigen

scientific article

Identification of an antigenic epitope for helper T lymphocytes from carcinoembryonic antigen

scientific article published in October 2002

Identification of peptide inhibitors of transforming growth factor beta 1 using a phage-displayed peptide library

scientific article published in August 2007

Immunization against hepatitis C virus with a fusion protein containing the extra domain A from fibronectin and the hepatitis C virus NS3 protein

scientific article

Immunization with a tumor-associated CTL epitope plus a tumor-related or unrelated Th1 helper peptide elicits protective CTL immunity

scientific article published on 01 June 2001

In vitro and in vivo down-regulation of regulatory T cell activity with a peptide inhibitor of TGF-beta1.

scientific article published in July 2008

In vivo cytotoxic T-lymphocyte induction may take place via CD8 T helper lymphocytes

scientific article published on 01 January 1995

Induction of Monocyte Chemoattractant Protein-1 and Interleukin-10 by TGF 1 in Melanoma Enhances Tumor Infiltration and Immunosuppression

scientific article published on 15 December 2010

Induction of antibodies against a peptide hapten does not require covalent linkage between the hapten and a class II presentable T helper peptide

scientific article published on 01 June 1991

Induction of cytotoxic T lymphocytes in mice against the principal neutralizing domain of HIV-1 by immunization with an engineered T-cytotoxic-T-helper synthetic peptide construct

scientific article published on 01 April 1992

Induction of cytotoxic T-cell response against hepatitis C virus structural antigens using a defective recombinant adenovirus

scientific article published on February 1997

Induction of multiepitopic and long-lasting immune responses against tumour antigens by immunization with peptides, DNA and recombinant adenoviruses expressing minigenes

scientific article published on 10 December 2008

Induction of neutralizing antibodies against human immunodeficiency virus type 1 using synthetic peptide constructs containing an immunodominant T-helper cell determinant from vpr.

scientific article published on July 1994

Induction of potent and long-lasting CD4 and CD8 T-cell responses against hepatitis C virus by immunization with viral antigens plus poly(I:C) and anti-CD40.

scientific article published on 22 January 2007

Insights on the amino acid side-chain interactions of a synthetic T-cell determinant

scientific article published on July 1991

Monocyte-derived dendritic cells from HCV-infected patients transduced with an adenovirus expressing NS3 are functional when stimulated with the TLR3 ligand poly(I:C).

scientific article

Overcoming class II-linked non-responsiveness to hepatitis B vaccine

scientific article published on 01 August 1994

Peptide inhibitors of transforming growth factor-beta enhance the efficacy of antitumor immunotherapy.

scientific article

Polarity of immunogens: implications for vaccine design

scientific article published in October 1990

Production of interleukin-2 in response to synthetic peptides from hepatitis C virus E1 protein in patients with chronic hepatitis C: relationship with the response to interferon treatment

scientific article published on July 1996

Simple strategy to induce antibodies of distinct specificity: Application to the mapping of gp120 and inhibition of HIV-1 infectivity

article

Specific and general HLA-DR binding motifs: comparison of algorithms

scientific article published in March 2000

T(h)1 but not T(h)0 cell help is efficient to induce cytotoxic T lymphocytes by immunization with short synthetic peptides

scientific article published on 01 December 1999

T-helper cell response to woodchuck hepatitis virus antigens after therapeutic vaccination of chronically-infected animals treated with lamivudine

scientific article published in July 2001

The extra domain A from fibronectin targets antigens to TLR4-expressing cells and induces cytotoxic T cell responses in vivo

scientific article published on 01 January 2007

Therapeutic vaccination of woodchucks against chronic woodchuck hepatitis virus infection.

scientific article published in October 1997

Topical application of a peptide inhibitor of transforming growth factor-beta1 ameliorates bleomycin-induced skin fibrosis

scientific article published on 01 September 2005

Tumor therapy in mice by using a tumor antigen linked to modulin peptides from Staphylococcus epidermidis

scientific article published on 15 September 2010

Upregulation of indoleamine 2,3-dioxygenase in hepatitis C virus infection

scientific article published on 17 January 2007

Vaccination against hepatitis C virus with dendritic cells transduced with an adenovirus encoding NS3 protein.

scientific article

Vaccination with an adenoviral vector encoding hepatitis C virus (HCV) NS3 protein protects against infection with HCV-recombinant vaccinia virus

scientific article published on December 2002

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