List of works - Naoya Hosono

A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression

scientific article

A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese

A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese

scientific journal article

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population

scientific journal article

A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population

scientific article published on 15 August 2010

A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese

scientific journal article

A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids

scientific journal article

A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population

scientific article

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.

scientific article published on 6 April 2009

A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci

scientific article

A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region

scientific journal article

A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population

scientific article published on 12 July 2011

A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility

scientific article published on 09 May 2010

Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility

scientific article published on 28 September 2010

Automated SNPs typing system based on the Invader assay

scientific article published on 10 March 2009

CYP2D6 genotyping for functional-gene dosage analysis by allele copy number detection

scientific article published on 18 June 2009

Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations

scientific article published on 19 February 2012

Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility

scientific journal article

Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count

scientific article published on 18 February 2010

Criterion values for multiplex SNP genotyping by the invader assay.

scientific article published on 21 August 2009

Development of new HLA-B*3505 genotyping method using Invader assay ⬇️

scientific article published on October 1, 2010

Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays

scientific article published on July 2010

Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients

scientific article published on 23 September 2011

Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk

scientific article published on 19 August 2009

Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes

scientific article published on 29 March 2012

Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus

Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma

scientific article published on 17 April 2011

Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population

scientific journal article

Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population

scientific article published on 11 September 2011

Genome-wide association study of hematological and biochemical traits in a Japanese population

scientific article

Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population

scientific article

Identification of nine novel loci associated with white blood cell subtypes in a Japanese population

scientific article

Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy

scientific article

Impact of LIMK1, MMP2 and TNF-α variations for intracranial aneurysm in Japanese population.

scientific article published on 13 January 2011

Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis

scientific article published in September 2013

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

scientific article

Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies

scientific article

Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response

scientific article published on September 2010

Making a haplotype catalog with estimated frequencies based on SNP homozygotes

scientific article published on 20 May 2010

Multiplex PCR-based real-time invader assay (mPCR-RETINA): a novel SNP-based method for detecting allelic asymmetries within copy number variation regions

scientific article published on 01 January 2008

New pharmacogenetic test for detecting an HLA-A*31: 01 allele using the InvaderPlus assay

scientific article

Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese

scientific article published on 7 March 2012

Optineurin mutations in Japanese amyotrophic lateral sclerosis

scientific article published on 08 January 2011

PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data

scientific article

Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients

scientific article published on February 2010

Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations

scientific article published on 26 September 2010

Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing

article

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

scientific article

List of works by Naoya Hosono

A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression

A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese

A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population

A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population

A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese

A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids

A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.

A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci

A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region

A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population

A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility

Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility

Automated SNPs typing system based on the Invader assay

CYP2D6 genotyping for functional-gene dosage analysis by allele copy number detection

Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations

Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility

Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count

Criterion values for multiplex SNP genotyping by the invader assay.

Development of new HLA-B*3505 genotyping method using Invader assay ⬇️

Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays

Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients

Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk

Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes

Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus

Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma

Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population

Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population

Genome-wide association study of hematological and biochemical traits in a Japanese population

Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population

Identification of nine novel loci associated with white blood cell subtypes in a Japanese population

Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy

Impact of LIMK1, MMP2 and TNF-α variations for intracranial aneurysm in Japanese population.

Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies

Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response

Making a haplotype catalog with estimated frequencies based on SNP homozygotes

Multiplex PCR-based real-time invader assay (mPCR-RETINA): a novel SNP-based method for detecting allelic asymmetries within copy number variation regions

New pharmacogenetic test for detecting an HLA-A*31: 01 allele using the InvaderPlus assay

Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese

Optineurin mutations in Japanese amyotrophic lateral sclerosis

PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data

Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients

Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations

Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators