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List of works by Irena Nalepa

A comparison of norepinephrine stimulated inositol phosphate accumulation in cerebral cortex of the Acomys cahirinus, the laboratory mice and the rat

scientific article published on 01 July 1988

A lack of α1A-adrenergic receptor-mediated antidepressant-like effects of S-(+)-niguldipine and B8805-033 in the forced swim test

scientific article published on 19 November 2015

A possible physiological role for cerebral tetrahydroisoquinolines

scientific article

Acute and repeated treatment with the 5-HT7 receptor antagonist SB 269970 induces functional desensitization of 5-HT7 receptors in rat hippocampus

scientific article published in January 2012

Anticonvulsant effect of pterostilbene and its influence on the anxiety- and depression-like behavior in the pentetrazol-kindled mice: behavioral, biochemical, and molecular studies

scientific article published in November 2021

Antidepressants Differentially Regulate Intracellular Signaling from α1-Adrenergic Receptor Subtypes In Vitro

scientific article published in May 2021

Antidepressants: past, present and future

scientific article

Assessment of leukocyte activity in mice devoid of the glucocorticoid receptor in the noradrenergic system (GR(DBHCre)).

scientific article

Avoidance learning during antidepressant withdrawal in mice

scientific article published in January 1991

Behavioural and biochemical studies of citalopram and WAY 100635 in rat chronic mild stress model

scientific article published in May 2002

Beta down-regulation induced by repeated vasopressin treatment

scientific article published in March 1990

Brief maternal separation affects brain α1-adrenoceptors and apoptotic signaling in adult mice

scientific article published on 12 October 2013

Carane derivative stereoisomers of different local anaesthetic and antiplatelet activity similarly potentiate forskolin-stimulated cyclic AMP response and bind to beta-adrenoceptors in the rat brain cortex

scientific article published in November 2004

Centpropazine affinity to cortical noradrenergic receptors and effect on their responsiveness in the rat.

scientific article published in March 1993

Changes induced by formalin pain in central alpha1-adrenoceptor density are modulated by adenosine receptor agonists

scientific article published on 23 March 2010

Chronic restraint stress induces changes in the cerebral Galpha 12/13 and Rho-GTPase signaling network

scientific article published in August 2021

Chronic treatment with citalopram does not affect the expression of alpha1-adrenergic receptor (alpha1-AR) subtypes.

scientific article published in November 2004

Chronic treatment with electroconvulsive shock may modulate the immune function of macrophages

scientific article published in December 2008

Concomitant administration of fluoxetine and amantadine modulates the activity of peritoneal macrophages of rats subjected to a forced swimming test

scientific article

Cryptic peptide derived from the rat neuropeptide FF precursor affects G-proteins linked to opioid receptors in the rat brain

scientific article

Depressive-like effect of prenatal exposure to DDT involves global DNA hypomethylation and impairment of GPER1/ESR1 protein levels but not ESR2 and AHR/ARNT signaling.

scientific article

Depressive-like immobility behavior and genotype × stress interactions in male mice of selected strains

scientific article published on 3 March 2016

Different calcium requirements during incorporation of myo-inositol into membrane lipids for phosphatidylinositol hydrolysis stimulated by carbachol and noradrenaline.

scientific article published in July 1990

Different mechanisms of beta-adrenoceptor down-regulation by chronic imipramine and electroconvulsive treatment: possible role for protein kinase C.

scientific article published in September 1991

Different regulation of phospholipase D activity in glioma C6 cells by sphingosine, propranolol, imipramine and phorbol ester.

scientific article published in June 2000

Disruption of glucocorticoid receptors in the noradrenergic system leads to BDNF up-regulation and altered serotonergic transmission associated with a depressive-like phenotype in female GR(DBHCre) mice

scientific article published on 7 August 2015

Does Ca2+ channel blockade modulate the antidepressant-induced changes in mechanisms of adrenergic transduction?

scientific article published on 01 January 1997

Does the presence of morphine counteract adaptive changes in expression of G-protein alpha subunits mRNA induced by chronic morphine treatment?

scientific article published in January 2007

Effect of cocaine on responsiveness of alpha(1)-adrenergic receptors in rat cerebral cortex: modulation by GABA-mimetic drugs.

scientific article published in November 2008

Effect of cocaine sensitization on alpha1-adrenoceptors in brain regions of the rat: an autoradiographic analysis

scientific article

Effect of combined treatment with paroxetine and transcranial magnetic stimulation (TMS) on the mitogen-induced proliferative response of rat lymphocytes.

scientific article published in November 2002

Effect of repeated administration of paroxetine and electroconvulsive shock on the proliferative response of lymphocytes and the synthesis of nitric oxide by macrophages in rats

scientific article published in June 2005

Effects of co-administration of fluoxetine and risperidone on properties of peritoneal and pleural macrophages in rats subjected to the forced swimming test

scientific article

Effects of diisopropyl fluorophosphate on muscarinic-M1-receptors and on receptor-mediated responsiveness of the phosphatidyl-inositol system in the cerebral cortex of rats

scientific article published on January 1, 1992

Effects of excitatory amino acids on inositol phosphate accumulation in slices of the cerebral cortex of young and aged rats

scientific article

Effects of morphine and methadone treatment on mRNA expression of Gα(i) subunits in rat brains.

scientific article published on November 2010

Effects of the noradrenergic neurotoxin DSP-4 on the expression of α1-adrenoceptor subtypes after antidepressant treatment ⬇️

scientific article published on January 1, 2011

Enhancement of the responsiveness of cortical adrenergic receptors by chronic administration of the 5-hydroxytryptamine uptake inhibitor citalopram

scientific article published in June 1993

Erratum to: Neuroprotective Effect of the Endogenous Amine 1MeTIQ in an Animal Model of Parkinson's Disease

scientific article published on 01 August 2016

Fear memory-induced alterations in the mRNA expression of G proteins in the mouse brain and the impact of immediate posttraining treatment with morphine

scientific article published on 03 April 2019

Formalin hindpaw injection induces changes in the [3H]prazosin binding to alpha1-adrenoceptors in specific regions of the mouse brain and spinal cord

scientific article

Gender differences in genetic mouse models evaluated for depressive-like and antidepressant behavior

scientific article

Gender-dependent activity of CYP3A is indirectly modified by GR in the noradrenergic system

scientific article

Gene Expression Changes Induced by Exposure of RAW 264.7 Macrophages to Particulate Matter of Air Pollution: The Role of Endotoxins

scientific article published on 10 August 2022

Genetic lesions of the noradrenergic system trigger induction of oxidative stress and inflammation in the ventral midbrain

scientific article published in May 2022

Imipramine administration induces changes in the phosphorylation of FAK and PYK2 and modulates signaling pathways related to their activity.

scientific article published on 24 November 2015

Inactivation of glucocorticoid receptor in noradrenergic system influences anxiety- and depressive-like behavior in mice

scientific article

Increased responsiveness of the cerebral cortical phosphatidylinositol system to noradrenaline and carbachol in senescent rats

scientific article published on 01 December 1989

Involvement of Macrophage Inflammatory Protein-1 Family Members in the Development of Diabetic Neuropathy and Their Contribution to Effectiveness of Morphine.

scientific article

Involvement of protein kinase C in the mechanism of in vitro effects of imipramine on generation of second messengers by noradrenaline in cerebral cortical slices of the rat.

scientific article

Isomer-nonspecific action of dichlorodiphenyltrichloroethane on aryl hydrocarbon receptor and G-protein-coupled receptor 30 intracellular signaling in apoptotic neuronal cells

scientific article

Lack of beta adrenoceptor desensitization in brain following the dual noradrenaline and serotonin reuptake inhibitor venlafaxine

scientific article published in August 1998

Lack of riluzole efficacy in the progression of the neurodegenerative phenotype in a new conditional mouse model of striatal degeneration

scientific article

Macrophages and depression - a misalliance or well-arranged marriage?

scientific article

Magnetic field inhibits isolated lymphocytes' proliferative response to mitogen stimulation

article

Metabolic Response of RAW 264.7 Macrophages to Exposure to Crude Particulate Matter and a Reduced Content of Organic Matter

scientific article published on 30 August 2021

Minocycline influences the anti-inflammatory interleukins and enhances the effectiveness of morphine under mice diabetic neuropathy

scientific article

Modulation by Mianserin Pretreatment of the Chronic Electroconvulsive Shock Effects on the Adrenergic System in the Cerebral Cortex of the Rat

scientific article published in July 1996

Modulation by cationic amphiphilic drugs of serine base-exchange, phosholipase d and intracellular calcium homeostasis in glioma C6 cells.

scientific article published in September 2002

Morphine-induced place preference affects mRNA expression of G protein α subunits in rat brain

scientific article published in January 2012

Neuroprotective Effect of the Endogenous Amine 1MeTIQ in an Animal Model of Parkinson's Disease

scientific article published on 25 August 2015

Nicotine potentiates imipramine-induced effects on catecholamine metabolism: possible relation to antidepressant activity

scientific article

Nicotine produces antidepressant-like actions: Behavioral and neurochemical evidence.

scientific article published in May 2005

Norepinephrine-independent regulation of GRII mRNA in vivo by a tricyclic antidepressant.

scientific article published in July 1995

Novel multi-target azinesulfonamides of cyclic amine derivatives as potential antipsychotics with pro-social and pro-cognitive effects

scientific article

Opposite effect of simple tetrahydroisoquinolines on amphetamine- and morphine-stimulated locomotor activity in mice

scientific article published in January 2001

P-2 Effects of electroconvulsive seizures on protein kinase C-induced potentiation of cyclic AMP response are modified by pretreatment with antidepressant drugs

scientific article published in April 1996

Paroxetine pretreatment does not change the effects induced in the rat cortical beta-adrenergic receptor system by repetitive transcranial magnetic stimulation and electroconvulsive shock

scientific article published on 24 August 2009

Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury

scientific article published on 26 September 2019

Pharmacological actions of the antidepressant venlafaxine beyond aminergic receptors

scientific article published on 01 March 1999

Phorbol ester and central chemosympathectomy augment beta-adrenoceptor response by different mechanisms

scientific article published in March 1993

Prenatal stress affects insulin-like growth factor-1 (IGF-1) level and IGF-1 receptor phosphorylation in the brain of adult rats

scientific article published on 22 July 2014

Psychosocial Crowding Stress-Induced Changes in Synaptic Transmission and Glutamate Receptor Expression in the Rat Frontal Cortex

scientific article published on 16 February 2021

Repeated imipramine and electroconvulsive shock increase alpha 1A-adrenoceptor mRNA level in rat prefrontal cortex

scientific article

Reserpinization enhances electroconvulsive treatment effects on cortical alpha 1-adrenoceptors

scientific article published on 01 November 1988

Retrieval associated cholinergic activity and its inhibition by memory updating

scientific article published in January 1994

Reversal by imipramine of beta-adrenoceptor up-regulation induced in a chronic mild stress model of depression

scientific article published on 01 August 1994

Second messengers: rate of formation as an index of receptor reactivity

scientific article published on January 1990

Selective Depletion of CREB in Serotonergic Neurons Affects the Upregulation of Brain-Derived Neurotrophic Factor Evoked by Chronic Fluoxetine Treatment

Selective ablation of glucocorticoid receptors in the noradrenergic system affects evening corticosterone levels in a sex-dependent manner

scientific article

Spinal CCL1/CCR8 signaling interplay as a potential therapeutic target - Evidence from a mouse diabetic neuropathy model

scientific article published on 25 September 2017

Splenectomy and Adoptive Cell Transfer Reveal a Prominent Role for Splenic Memory Lymphocytes in the Development of Chronic Relapsing Experimental Autoimmune Encephalomyelitis

scientific article published on 01 October 2000

Spontaneous head twitches in aged rats: behavioral and molecular study

scientific article published on 24 October 2022

Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism

article

Strain differences in changes in some parameters of cerebral cortical adrenergic system following chronic imipramine administration to rats

scientific article

Suppression of pro-inflammatory cytokine expression and lack of anti-depressant-like effect of fluoxetine in lipopolysaccharide-treated old female mice

scientific article published on 28 April 2017

The Air We Breathe: Air Pollution as a Prevalent Proinflammatory Stimulus Contributing to Neurodegeneration

scientific article published in 2021

The Protective Effect of Repeated 1MeTIQ Administration on the Lactacystin-Induced Impairment of Dopamine Release and Decline in TH Level in the Rat Brain

scholarly article by Agnieszka Wąsik et al published October 2018 in Neurotoxicity Research

The antagonistic effect of separate and consecutive chronic treatment with imipramine and ECS on the inhibition of alpha 1-adrenoceptor activity by protein kinase C.

scientific article published in September 1993

The dopamine D4 receptor VNTR in Polish schizophrenia patients

scientific article published in February 2005

The effect of (-)-4-(2-hydroxy-3(N-isopropylamino)-propoxyimino)-cis-carane on basal and forskolin-stimulated accumulation of cyclic AMP in the cerebral cortical slices of the rat.

scientific article published in May 1994

The effect of calcium channel blockade on the action of chronic ECT and imipramine on responses of alpha 1- and beta-adrenoceptors in the rat cerebral cortex

scientific article published in March 1993

The effect of psychotropic drugs on the interaction of protein kinase C with second messenger systems in the rat cerebral cortex

scientific article published on January 1994

The effects of chlorpromazine and haloperidol on second messenger systems related to adrenergic receptors

scientific article published in July 1993

The influence of CaMKII and ERK phosphorylation on BDNF changes observed in mice selectively devoid of CREB in serotonergic or noradrenergic neurons

scientific article published on 09 April 2019

The influence of electroshock on adrenoceptor function in rat brain cerebral cortex: selectivity for the alpha-adrenoceptor site

scientific article published on 01 October 1988

The interaction of tetrahydroisoquinoline derivatives with antinociceptive action of morphine and oxotremorine in mice

scientific article published in November 2003

The responsiveness of cerebral cortical adrenergic receptors after chronic administration of atypical antidepressant mianserin

scientific article published on March 1994

Transgenic mice lacking CREB and CREM in noradrenergic and serotonergic neurons respond differently to common antidepressants on tail suspension test.

scientific article published on 18 October 2017

Using reverse transcription and a competitive polymerase chain reaction for quantification of alpha1B-adrenoceptor mRNA.

scientific article published in July 2002

α1-Adrenergic receptor subtypes in the central nervous system: insights from genetically engineered mouse models.

scientific article published on January 2013

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