List of works - Nancy L. Oleinick

A requirement for bid for induction of apoptosis by photodynamic therapy with a lysosome- but not a mitochondrion-targeted photosensitizer

scientific article

ATR/CHK1 inhibitors and cancer therapy

scientific article

Activated T cells exhibit increased uptake of silicon phthalocyanine Pc 4 and increased susceptibility to Pc 4-photodynamic therapy-mediated cell death

scientific article published on 10 May 2016

Apoptosis Mechanisms Related to the Increased Sensitivity of Jurkat T-cells versus A431 Epidermoid Cells to Photodynamic Therapy with the Phthalocyanine Pc 4

Apoptosis during photodynamic therapy-induced ablation of RIF-1 tumors in C3H mice: electron microscopic, histopathologic and biochemical evidence

scientific article published on December 1993

Apoptosis mechanisms related to the increased sensitivity of Jurkat T-cells vs A431 epidermoid cells to photodynamic therapy with the phthalocyanine Pc 4.

scientific article published on 23 January 2008

Assessing autophagy in the context of photodynamic therapy

scientific article

Association between the photodynamic loss of Bcl-2 and the sensitivity to apoptosis caused by phthalocyanine photodynamic therapy

scientific article published in July 2003

Association of Ceramide Accumulation with Photodynamic Treatment‐Induced Cell Death ⬇️

scientific article published on 01 July 1998

Atg7 deficiency increases resistance of MCF-7 human breast cancer cells to photodynamic therapy

scientific article published on February 2010

Bax is essential for mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy ⬇️

scientific article published on October 20, 2003

Binding to and photo-oxidation of cardiolipin by the phthalocyanine photosensitizer Pc 4

scientific article

Cell Death Pathways Associated with Photodynamic Therapy: An Update

scientific article published on 16 November 2017

Ceramide generation in response to photodynamic treatment of L5178Y mouse lymphoma cells

scientific article published on 01 May 1997

Chromatin Compaction and the Efficiency of Formation of DNA-Protein Crosslinks in γ-Irradiated Mammalian Cells

scientific article published on 01 February 1992

Comparison of DNA-protein cross-links induced by 4'-(9-acridinylamino)-methanesulfon-m-anisidide and by gamma-radiation

scientific article published in February 1989

Considerations on the role of cardiolipin in cellular responses to PDT

scientific article published on 14 June 2004

Copper ion-mediated sensitization of nuclear matrix attachment sites to ionizing radiation

scientific article published in June 1993

Cutaneous penetration of the topically applied photosensitizer Pc 4 as detected by intravital 2-photon laser scanning microscopy

scientific article published on 23 February 2012

Cytotoxic and mutagenic effects of the photodynamic action of chloroaluminum phthalocyanine and visible light in L5178Y cells

scientific article published on 01 January 1989

DNA lesions and DNA degradation in mouse lymphoma L5178Y cells after photodynamic treatment sensitized by chloroaluminum phthalocyanine

scientific article published on 01 September 1989

DNA-protein cross-links: new insights into their formation and repair in irradiated mammalian cells

scientific article published in January 1986

Deformable and rigid registration of MRI and microPET images for photodynamic therapy of cancer in mice.

scientific article published on March 2006

Delivery of the photosensitizer Pc 4 in PEG-PCL micelles for in vitro PDT studies

scientific article

Differential Processing of Ultraviolet or Ionizing Radiation-induced DNA—protein Cross-links in Chinese Hamster Cells ⬇️

scientific article published on 01 December 1984

Differential dependence on chromatin structure for copper and iron ion induction of DNA double-strand breaks

scientific article published on February 1995

Differential responses of Mcl-1 in photosensitized epithelial vs lymphoid-derived human cancer cells

scientific article published on October 2005

Dissociation of mitochondrial depolarization from cytochrome c release during apoptosis induced by photodynamic therapy

scientific article

Domain-dependent photodamage to Bcl-2. A membrane anchorage region is needed to form the target of phthalocyanine photosensitization

scientific article published on 11 October 2002

EGFR-mediated intracellular delivery of Pc 4 nanoformulation for targeted photodynamic therapy of cancer: in vitro studies ⬇️

scientific article published on October 22, 2011

Enhancement of photodynamic cell killing (with chloroaluminum phthalocyanine) by treatment of V79 cells with the ionophore nigericin.

scientific article published on March 1990

Etk/Bmx, a PH-domain containing tyrosine kinase, protects prostate cancer cells from apoptosis induced by photodynamic therapy or thapsigargin

scientific article published on 01 June 1999

Fluorescence resonance energy transfer reveals a binding site of a photosensitizer for photodynamic therapy ⬇️

scientific article published on September 1, 2003

Formation and repair of DNA-protein crosslinks in newly replicated DNA.

scientific article published on December 1989

Formation of DNA-protein cross-links in mammalian cells by levuglandin E2.

scientific article published on April 1993

Gamma radiation as a probe of chromatin structure: damage to and repair of active chromatin in the metaphase chromosome

scientific article published on 01 June 1984

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

scientific article

High-field magnetic resonance imaging of the response of human prostate cancer to Pc 4-based photodynamic therapy in an animal model

scientific article

Hypersensitivity of DNA in transcriptionally active chromatin to ionizing radiation ⬇️

scientific article published on October 29, 1982

In Vivo Small Animal Imaging for Early Assessment of Therapeutic Efficacy of Photodynamic Therapy for Prostate Cancer.

scientific article published on March 2007

Induction of DNA damage in gamma-irradiated nuclei stripped of nuclear protein classes: differential modulation of double-strand break and DNA-protein crosslink formation

scientific article published on 01 July 1994

Induction of DNA strand breaks in transcriptionally active DNA sequences of mouse cells by low doses of ionizing radiation

scientific article published on 01 September 1987

Induction of DNA-protein cross-links in Chinese hamster cells by the photodynamic action of chloroaluminum phthalocyanine and visible light

scientific article published on 01 September 1988

Initiation of autophagy by photodynamic therapy

scientific article

Large mutagenic lesions are induced by photodynamic therapy in murine L5178Y lymphoblasts

scientific article

Lysosomal cathepsin initiates apoptosis, which is regulated by photodamage to Bcl-2 at mitochondria in photodynamic therapy using a novel photosensitizer, ATX-s10 (Na).

scientific article published in August 2006

Modification of DNA damage in transcriptionally active vs. bulk chromatin

scientific article published on 01 August 1986

Multiscale Fuzzy C-Means Image Classification for Multiple Weighted MR Images for the Assessment of Photodynamic Therapy in Mice.

scientific article published on March 2007

Mutagenicity of Photodynamic Therapy as Compared to UVC and Ionizing Radiation in Human and Murine Lymphoblast Cell Lines ⬇️

scientific article published on November 1, 1997

New phthalocyanine photosensitizers for photodynamic therapy

scientific article published on February 1993

New phthalocyanines for photodynamic virus inactivation in red blood cell concentrates

scientific article

Nuclear matrix proteins are crosslinked to transcriptionally active gene sequences by ionizing radiation

scientific article

Nuclear structure and the microdistribution of radiation damage in DNA.

scientific article

Optimization of a nanomedicine-based silicon phthalocyanine 4 photodynamic therapy (Pc 4-PDT) strategy for targeted treatment of EGFR-overexpressing cancers

scientific article

Oxidative modification of cytochrome c by singlet oxygen.

scientific article published on 4 January 2008

Pc 4 photodynamic therapy of U87-derived human glioma in the nude rat.

scientific article

Phospholipase activation triggers apoptosis in photosensitized mouse lymphoma cells

scientific article published on 01 December 1993

Photo-oxidation of cardiolipin and cytochrome c with bilayer-embedded Pc 4.

scientific article published on 25 May 2010

Photodamage to multiple Bcl-xL isoforms by photodynamic therapy with the phthalocyanine photosensitizer Pc 4.

scientific article published on December 2003

Photodynamic therapy and cell death pathways

scientific article published on January 2010

Photodynamic therapy induces rapid cell death by apoptosis in L5178Y mouse lymphoma cells

scientific article published on 01 November 1991

Photodynamic therapy of cottontail rabbit papillomavirus-induced papillomas in a severe combined immunodeficient mouse xenograft system

scientific article published on March 2010

Photodynamic therapy of human squamous cell carcinoma in vitro and in xenografts in nude mice

scientific article published on September 1993

Photodynamic therapy with Pc 4 induces apoptosis of Candida albicans.

scientific article published on 13 June 2011

Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice

scientific article

Photodynamic therapy with the phthalocyanine photosensitizer Pc 4: the case experience with preclinical mechanistic and early clinical-translational studies

scientific article

Photodynamic therapy with the silicon phthalocyanine pc 4 induces apoptosis in mycosis fungoides and sezary syndrome

scientific article published on 12 December 2010

Photodynamic therapy-induced apoptosis in lymphoma cells: translocation of cytochrome c causes inhibition of respiration as well as caspase activation

scientific article published on 01 February 1999

Photodynamic therapy-induced death of HCT 116 cells: Apoptosis with or without Bax expression

scientific article published in December 2005

Photodynamic therapy-induced death of MCF-7 human breast cancer cells: a role for caspase-3 in the late steps of apoptosis but not for the critical lethal event

scientific article

Photofrin II photosensitization is mutagenic at the tk locus in mouse L5178Y cells

scientific article published on 01 January 1992

Photosensitization of intact heart mitochondria by the phthalocyanine Pc 4: Correlation of structural and functional deficits with cytochrome c release.

scientific article published on 25 May 2010

Phthalocyanine 4 (Pc 4) photodynamic therapy of human OVCAR-3 tumor xenografts

scientific article

Phthalocyanine 4 photodynamic therapy-induced apoptosis of mouse L5178Y-R cells results from a delayed but extensive release of cytochrome c from mitochondria

scientific article published in April 2001

Poly(ADP-ribose) and the response of cells to ionizing radiation

scientific article

Post-treatment interactions of photodynamic and radiation-induced cytotoxic lesions

scientific article published on September 1990

Preliminary clinical and pharmacologic investigation of photodynamic therapy with the silicon phthalocyanine photosensitizer pc 4 for primary or metastatic cutaneous cancers.

scientific article

Promotion of photodynamic therapy-induced apoptosis by stress kinases

scientific article published on 01 September 1999

Promotion of photodynamic therapy-induced apoptosis by the mitochondrial protein Smac/DIABLO: dependence on Bax.

scientific article published in August 2002

Protease activation and cleavage of poly(ADP-ribose) polymerase: an integral part of apoptosis in response to photodynamic treatment ⬇️

scientific article published on 01 March 1998

Protection by Bcl-2 against apoptotic but not autophagic cell death after photodynamic therapy

scientific article published on 12 November 2007

Radiation Therapy Combined with Cowpea Mosaic Virus Nanoparticle in Situ Vaccination Initiates Immune-Mediated Tumor Regression.

scientific article published on 2 April 2018

Radiation-induced binding of DNA from irradiated mammalian cells to hydroxyapatite columns

scientific article published on September 1990

Radioprotection against the Formation of DNA Double-Strand Breaks in Cellular DNA but Not Native Cellular Chromatin by the Polyamine Spermine

scientific article published on 01 August 1997

Radioprotection of Cellular Chromatin by the Polyamines Spermine and Putrescine: Preferential Action against Formation of DNA-Protein Crosslinks

scientific article published on June 1, 1998

Radiosensitization of Human Cervical Cancer Cells by Inhibiting Ribonucleotide Reductase: Enhanced Radiation Response at Low-Dose Rates ⬇️

scientific article published on April 4, 2011

Radiosensitization of non-small-cell lung cancer cells and xenografts by the interactive effects of pemetrexed and methoxyamine.

scientific article

Rapid Tyrosine Phosphorylation of HS1 in the Response of Mouse Lymphoma L5178Y‐R Cells to Photodynamic Treatment Sensitized by the Phthalocyanine Pc 4 ⬇️

scientific article published on 01 July 1997

Repair of chromatin damage in glutathione-depleted V-79 cells: comparison of oxic and hypoxic conditions.

scientific article published in October 1988

Resistance of the Nucleosomal Organization of Eucaryotic Chromatin to Ionizing Radiation

scientific article published on September 1, 1982

Signaling From Lysosomes Enhances Mitochondria-Mediated Photodynamic Therapy In Cancer Cells

scientific article

Silicon phthalocyanine (pc 4) photodynamic therapy is a safe modality for cutaneous neoplasms: results of a phase 1 clinical trial ⬇️

scientific article published on December 1, 2010

Staurosporine-induced death of MCF-7 human breast cancer cells: a distinction between caspase-3-dependent steps of apoptosis and the critical lethal lesions

scientific article

Structural factors and mechanisms underlying the improved photodynamic cell killing with silicon phthalocyanine photosensitizers directed to lysosomes versus mitochondria

scientific article

Targeting of mitochondria by 10-N-alkyl acridine orange analogues: role of alkyl chain length in determining cellular uptake and localization.

scientific article published on 25 April 2008

The death of human cancer cells following photodynamic therapy: apoptosis competence is necessary for Bcl-2 protection but not for induction of autophagy

scientific article

The effect of L-buthionine sulfoximine on the aerobic radiation response of A549 human lung carcinoma cells

scientific article published in July 1986

The fate of DNA-protein crosslinks formed in gamma-irradiated metaphase cells

scientific article published on 01 August 1990

The formation, identification, and significance of DNA-protein cross-links in mammalian cells

scientific article

The induction of partial resistance to photodynamic therapy by the protooncogene BCL-2

scientific article published on 01 November 1996

The peripheral benzodiazepine receptor in photodynamic therapy with the phthalocyanine photosensitizer Pc 4.

scientific article published on June 2002

The photobiology of photodynamic therapy: cellular targets and mechanisms

scientific article published on 01 November 1998

The role of DNA damage and repair in the function of eukaryotic genes: radiation-induced single-strand breaks and their rejoining in chromosomal and extrachromosomal ribosomal DNA of tetrahymena

scientific article published on 01 April 1980

The role of apoptosis in response to photodynamic therapy: what, where, why, and how.

scientific article

The sensitivity of active and inactive chromatin to ionizing radiation-induced DNA strand breakage

scientific article published on 01 January 1982

The synthesis, photophysical and photobiological properties and in vitro structure-activity relationships of a set of silicon phthalocyanine PDT photosensitizers

scientific article published on March 1997

Topical delivery of a preformed photosensitizer for photodynamic therapy of cutaneous lesions

scientific article published on 13 February 2012

Ultra-High Dose Rate Effect on Circulating Immune Cells: A Potential Mechanism for FLASH Effect?

scientific article published on 05 May 2020

Variation in Photodynamic Efficacy during the Cellular Uptake of Two Phthalocyanine Photosensitizers ⬇️

scientific article published on June 1, 1998

List of works by Nancy L. Oleinick

A requirement for bid for induction of apoptosis by photodynamic therapy with a lysosome- but not a mitochondrion-targeted photosensitizer

ATR/CHK1 inhibitors and cancer therapy

Activated T cells exhibit increased uptake of silicon phthalocyanine Pc 4 and increased susceptibility to Pc 4-photodynamic therapy-mediated cell death

Apoptosis Mechanisms Related to the Increased Sensitivity of Jurkat T-cells versus A431 Epidermoid Cells to Photodynamic Therapy with the Phthalocyanine Pc 4

Apoptosis during photodynamic therapy-induced ablation of RIF-1 tumors in C3H mice: electron microscopic, histopathologic and biochemical evidence

Apoptosis mechanisms related to the increased sensitivity of Jurkat T-cells vs A431 epidermoid cells to photodynamic therapy with the phthalocyanine Pc 4.

Assessing autophagy in the context of photodynamic therapy

Association between the photodynamic loss of Bcl-2 and the sensitivity to apoptosis caused by phthalocyanine photodynamic therapy

Association of Ceramide Accumulation with Photodynamic Treatment‐Induced Cell Death ⬇️

Atg7 deficiency increases resistance of MCF-7 human breast cancer cells to photodynamic therapy

Bax is essential for mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy ⬇️

Binding to and photo-oxidation of cardiolipin by the phthalocyanine photosensitizer Pc 4

Cell Death Pathways Associated with Photodynamic Therapy: An Update

Ceramide generation in response to photodynamic treatment of L5178Y mouse lymphoma cells

Chromatin Compaction and the Efficiency of Formation of DNA-Protein Crosslinks in γ-Irradiated Mammalian Cells

Comparison of DNA-protein cross-links induced by 4'-(9-acridinylamino)-methanesulfon-m-anisidide and by gamma-radiation

Considerations on the role of cardiolipin in cellular responses to PDT

Copper ion-mediated sensitization of nuclear matrix attachment sites to ionizing radiation

Cutaneous penetration of the topically applied photosensitizer Pc 4 as detected by intravital 2-photon laser scanning microscopy

Cytotoxic and mutagenic effects of the photodynamic action of chloroaluminum phthalocyanine and visible light in L5178Y cells

DNA lesions and DNA degradation in mouse lymphoma L5178Y cells after photodynamic treatment sensitized by chloroaluminum phthalocyanine

DNA-protein cross-links: new insights into their formation and repair in irradiated mammalian cells

Deformable and rigid registration of MRI and microPET images for photodynamic therapy of cancer in mice.

Delivery of the photosensitizer Pc 4 in PEG-PCL micelles for in vitro PDT studies

Differential Processing of Ultraviolet or Ionizing Radiation-induced DNA—protein Cross-links in Chinese Hamster Cells ⬇️

Differential dependence on chromatin structure for copper and iron ion induction of DNA double-strand breaks

Differential responses of Mcl-1 in photosensitized epithelial vs lymphoid-derived human cancer cells

Dissociation of mitochondrial depolarization from cytochrome c release during apoptosis induced by photodynamic therapy

Domain-dependent photodamage to Bcl-2. A membrane anchorage region is needed to form the target of phthalocyanine photosensitization

EGFR-mediated intracellular delivery of Pc 4 nanoformulation for targeted photodynamic therapy of cancer: in vitro studies ⬇️

Enhancement of photodynamic cell killing (with chloroaluminum phthalocyanine) by treatment of V79 cells with the ionophore nigericin.

Etk/Bmx, a PH-domain containing tyrosine kinase, protects prostate cancer cells from apoptosis induced by photodynamic therapy or thapsigargin

Fluorescence resonance energy transfer reveals a binding site of a photosensitizer for photodynamic therapy ⬇️

Formation and repair of DNA-protein crosslinks in newly replicated DNA.

Formation of DNA-protein cross-links in mammalian cells by levuglandin E2.

Gamma radiation as a probe of chromatin structure: damage to and repair of active chromatin in the metaphase chromosome

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

High-field magnetic resonance imaging of the response of human prostate cancer to Pc 4-based photodynamic therapy in an animal model

Hypersensitivity of DNA in transcriptionally active chromatin to ionizing radiation ⬇️

In Vivo Small Animal Imaging for Early Assessment of Therapeutic Efficacy of Photodynamic Therapy for Prostate Cancer.

Induction of DNA damage in gamma-irradiated nuclei stripped of nuclear protein classes: differential modulation of double-strand break and DNA-protein crosslink formation

Induction of DNA strand breaks in transcriptionally active DNA sequences of mouse cells by low doses of ionizing radiation

Induction of DNA-protein cross-links in Chinese hamster cells by the photodynamic action of chloroaluminum phthalocyanine and visible light

Initiation of autophagy by photodynamic therapy

Large mutagenic lesions are induced by photodynamic therapy in murine L5178Y lymphoblasts

Lysosomal cathepsin initiates apoptosis, which is regulated by photodamage to Bcl-2 at mitochondria in photodynamic therapy using a novel photosensitizer, ATX-s10 (Na).

Modification of DNA damage in transcriptionally active vs. bulk chromatin

Multiscale Fuzzy C-Means Image Classification for Multiple Weighted MR Images for the Assessment of Photodynamic Therapy in Mice.

Mutagenicity of Photodynamic Therapy as Compared to UVC and Ionizing Radiation in Human and Murine Lymphoblast Cell Lines ⬇️

New phthalocyanine photosensitizers for photodynamic therapy

New phthalocyanines for photodynamic virus inactivation in red blood cell concentrates

Nuclear matrix proteins are crosslinked to transcriptionally active gene sequences by ionizing radiation

Nuclear structure and the microdistribution of radiation damage in DNA.

Optimization of a nanomedicine-based silicon phthalocyanine 4 photodynamic therapy (Pc 4-PDT) strategy for targeted treatment of EGFR-overexpressing cancers

Oxidative modification of cytochrome c by singlet oxygen.

Pc 4 photodynamic therapy of U87-derived human glioma in the nude rat.

Phospholipase activation triggers apoptosis in photosensitized mouse lymphoma cells

Photo-oxidation of cardiolipin and cytochrome c with bilayer-embedded Pc 4.

Photodamage to multiple Bcl-xL isoforms by photodynamic therapy with the phthalocyanine photosensitizer Pc 4.

Photodynamic therapy and cell death pathways

Photodynamic therapy induces rapid cell death by apoptosis in L5178Y mouse lymphoma cells

Photodynamic therapy of cottontail rabbit papillomavirus-induced papillomas in a severe combined immunodeficient mouse xenograft system

Photodynamic therapy of human squamous cell carcinoma in vitro and in xenografts in nude mice

Photodynamic therapy with Pc 4 induces apoptosis of Candida albicans.

Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice

Photodynamic therapy with the phthalocyanine photosensitizer Pc 4: the case experience with preclinical mechanistic and early clinical-translational studies

Photodynamic therapy with the silicon phthalocyanine pc 4 induces apoptosis in mycosis fungoides and sezary syndrome

Photodynamic therapy-induced apoptosis in lymphoma cells: translocation of cytochrome c causes inhibition of respiration as well as caspase activation

Photodynamic therapy-induced death of HCT 116 cells: Apoptosis with or without Bax expression

Photodynamic therapy-induced death of MCF-7 human breast cancer cells: a role for caspase-3 in the late steps of apoptosis but not for the critical lethal event

Photofrin II photosensitization is mutagenic at the tk locus in mouse L5178Y cells

Photosensitization of intact heart mitochondria by the phthalocyanine Pc 4: Correlation of structural and functional deficits with cytochrome c release.

Phthalocyanine 4 (Pc 4) photodynamic therapy of human OVCAR-3 tumor xenografts

Phthalocyanine 4 photodynamic therapy-induced apoptosis of mouse L5178Y-R cells results from a delayed but extensive release of cytochrome c from mitochondria

Poly(ADP-ribose) and the response of cells to ionizing radiation

Post-treatment interactions of photodynamic and radiation-induced cytotoxic lesions

Preliminary clinical and pharmacologic investigation of photodynamic therapy with the silicon phthalocyanine photosensitizer pc 4 for primary or metastatic cutaneous cancers.

Promotion of photodynamic therapy-induced apoptosis by stress kinases