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Authors whose works are in public domain in at least one jurisdiction

List of works by Elaine C Johnstone

"Intention to Analyze" in Pharmacogenomics Studies

A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS

scientific article

A cost-effectiveness analysis of genetic testing of the DRD2 Taq1A polymorphism to aid treatment choice for smoking cessation

scientific article

A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans

scientific article

A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21

article

A proof of concept randomised placebo controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to prevent weight gain on smoking cessation

scientific article

Aberrant P53 expression lacks prognostic or predictive significance in colorectal cancer: results from the VICTOR trial

scientific article published in March 2015

Adjuvant capecitabine plus bevacizumab versus capecitabine alone in patients with colorectal cancer (QUASAR 2): an open-label, randomised phase 3 trial

scientific article published on 19 September 2016

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

scientific article published on 14 May 2019

Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure

scientific article

Association between nicotinic acetylcholine receptor single nucleotide polymorphisms and smoking cessation

scientific article published on 17 December 2011

Association between the DRD2 gene Taq1A (C32806T) polymorphism and alcohol consumption in social drinkers

scientific article published in January 2005

Association between the serotonin transporter gene and alcohol consumption in social drinkers

scientific article

Association of COMT Val108/158Met genotype with smoking cessation

scientific article published on February 2008

Association of COMT Val108/158Met genotype with smoking cessation in a nicotine replacement therapy randomized trial

scientific article

Association of serotonin transporter gene polymorphism with nicotine dependence: no evidence for an interaction with trait neuroticism

article

Association of serotonin transporter genotype with selective processing of smoking-related stimuli in current smokers and ex-smokers

scientific article

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

scientific article

Association of the dopamine-β-hydroxylase gene with nicotine dependence: No evidence for mediation by personality

article

Association of the mu-opioid receptor gene with smoking cessation

scientific article published on 16 January 2007

Associations between weight change over 8 years and baseline body mass index in a cohort of continuing and quitting smokers

scientific article published on 6 October 2010

Bromocriptine use is associated with decreased smoking rates

scientific article

CHRNA3 rs1051730 genotype and short-term smoking cessation

scientific article

Cyclin D1 rare variants in UK multiple adenoma and early-onset colorectal cancer patients

scientific article

Determinants of the rate of nicotine metabolism and effects on smoking behavior

scientific article published on 01 October 2006

Differential Efficacy of Nicotine Replacement Among Overweight and Obese Women Smokers.

scientific article

Does the DRD2-Taq1 A polymorphism influence treatment response to bupropion hydrochloride for reduction of the nicotine withdrawal syndrome?

scientific article

Effect on adherence to nicotine replacement therapy of informing smokers their dose is determined by their genotype: a randomised controlled trial

scientific article (publication date: 2012)

Effectiveness of nicotine patches in relation to genotype in women versus men: randomised controlled trial

scientific article

Effects of dopamine D2 receptor gene polymorphisms on smoking cessation: abstinence and withdrawal symptoms

article

Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer

scientific article

Genes and cigarette smoking

scientific article published on 08 January 2008

Genetic clues to the molecular basis of tobacco addiction and progress towards personalized therapy

scientific article

Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis

scientific article

Genetic prognostic and predictive markers in colorectal cancer

scientific article published on 18 June 2009

Genetic testing: the future of smoking cessation therapy?

scientific article

Genetic variation in dopaminergic pathways and short-term effectiveness of the nicotine patch

scientific article published in February 2004

Genetic variation in the dopamine D4 receptor (DRD4) gene and smoking cessation: follow-up of a randomised clinical trial of transdermal nicotine patch

scientific article published on 27 March 2007

Genetic variation in the serotonin pathway and smoking cessation with nicotine replacement therapy: new data from the Patch in Practice trial and pooled analyses

scientific article

Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement

scientific article

Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1

scientific article

Identification of CYP2B6 sequence variants by use of multiplex PCR with allele-specific genotyping

scientific article published on 3 June 2004

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

scientific article published on 7 October 2014

Lack of Association of OPRM1 Genotype and Smoking Cessation

scientific article published on 18 September 2012

Lack of association of 5-HTTLPR genotype with smoking cessation in a nicotine replacement therapy randomized trial

scientific article published in February 2006

Lack of association of DRD2 rs1800497 (Taq1A) polymorphism with smoking cessation in a nicotine replacement therapy randomized trial

scientific article published on 8 March 2009

Level of nicotine replacement during a quit-smoking attempt

scientific article

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN.

scientific article

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

scientific article

Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series

article

Neuroticism mediates the association of the serotonin transporter gene with lifetime major depression

scientific article

New directions in the genetic mechanisms underlying nicotine addiction

scientific article published in April 2001

No association between functional catechol O-methyl transferase 1947A>G polymorphism and smoking initiation, persistent smoking or smoking cessation

scientific article

Pattern Recognition Receptor Polymorphisms as Predictors of Oxaliplatin Benefit in Colorectal Cancer

scientific article published on 01 August 2019

Pharmacogenetics of smoking cessation in general practice: results from the patch II and patch in practice trials

scientific article

Pharmacoproteomic characterisation of human colon and rectal cancer.

scientific article published on 3 November 2017

Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: final results of the VICTOR trial

scientific article published on 13 September 2010

Polymorphisms in dopamine metabolic enzymes and tobacco consumption in smokers: seeking confirmation of the association in a follow-up study

scientific article published in October 2002

Prognostic markers for colorectal cancer; estimating ploidy and stroma

scientific article published on 27 December 2017

Role of rare variants in undetermined multiple adenomatous polyposis and early-onset colorectal cancer

scientific article published on 09 August 2012

Smoking cessation, weight gain, and DRD4 -521 genotype

scientific article published in June 2006

Smoking status moderates the association of the dopamine D4 receptor (DRD4) gene VNTR polymorphism with selective processing of smoking-related cues

scientific article published on 7 March 2008

The Predictive Role of ERCC1 Status in Oxaliplatin Based Neoadjuvant Therapy for Metastatic Colorectal Cancer (mCRC) to the Liver

scientific article published on 27 February 2015

The dopamine D2 receptor C32806T polymorphism (DRD2 Taq1A RFLP) exhibits no association with smoking behaviour in a healthy UK population

scientific article published in September 2004

The genetic basis for smoking behavior: a systematic review and meta-analysis

scientific article published in August 2004

The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial

scientific article published on 02 August 2012

The serotonin transporter 5-HTTLPR polymorphism and treatment response to nicotine patch: follow-up of a randomized controlled trial

scientific article

The value of additional bevacizumab in patients with high-risk stroma-high colon cancer. A study within the QUASAR2 trial, an open-label randomized phase 3 trial

scientific article published on 15 February 2018

Trial Protocol: Using genotype to tailor prescribing of nicotine replacement therapy: a randomised controlled trial assessing impact of communication upon adherence.

scientific article

Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.

scientific article published on February 2013

Weekly versus basic smoking cessation support in primary care: a randomised controlled trial

scientific article

Weight change over eight years in relation to alcohol consumption in a cohort of continuing smokers and quitters

scientific article

What is the role and impact of molecular markers on treatment decisions for colorectal cancer in the adjuvant setting?

scientific article published on 01 October 2009

What is the role and impact of molecular markers on treatment decisions in the adjuvant setting of colorectal cancer?

scientific article published on 01 September 2008

Zyban for smoking cessation in a general practice setting: the response to an invitation to make a quit attempt

scientific article published in September 2004