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List of works by Hiroko Hashimoto

A novel method to generate single-cell-derived cancer-associated fibroblast clones

scientific article published on 31 March 2017

CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors

scientific article

Cancer cell invasion driven by extracellular matrix remodeling is dependent on the properties of cancer-associated fibroblasts

scientific article published on 15 September 2015

Clonal heterogeneity in osteogenic potential of lung cancer-associated fibroblasts: promotional effect of osteogenic progenitor cells on cancer cell migration

scientific article published on 27 April 2016

Collagen type I induces EGFR-TKI resistance in EGFR-mutated cancer cells via mTOR activation through Akt-independent pathway.

scientific article published on 27 April 2018

Ezrin-expressing lung adenocarcinoma cells and podoplanin-positive fibroblasts form a malignant microenvironment

scientific article published on 11 October 2014

Fibroblast-led cancer cell invasion is activated by epithelial-mesenchymal transition through platelet-derived growth factor BB secretion of lung adenocarcinoma

scientific article

Fibroblasts associated with cancer cells keep enhanced migration activity after separation from cancer cells: a novel character of tumor educated fibroblasts

scientific article published on August 2010

Fibroblasts-dependent invasion of podoplanin-positive cancer stem cells in squamous cell carcinoma

scientific article published on 09 February 2020

Interaction between cancer cells and cancer-associated fibroblasts after cisplatin treatment promotes cancer cell regrowth

scientific article published on 22 August 2019

Morphophenotype of floating colonies derived from a single cancer cell has a critical impact on tumor-forming activity

scientific article published on 7 January 2013

Organoid culture containing cancer cells and stromal cells reveals that podoplanin-positive cancer-associated fibroblasts enhance proliferation of lung cancer cells

scientific article published on 08 April 2019

Podoplanin-expressing cancer-associated fibroblasts inhibit small cell lung cancer growth

scientific article published in April 2015

Podoplanin-expressing cancer-associated fibroblasts lead and enhance the local invasion of cancer cells in lung adenocarcinoma

scientific article published on 20 February 2015

Podoplanin-positive cancer-associated fibroblasts in the tumor microenvironment induce primary resistance to EGFR-TKIs in lung adenocarcinoma with EGFR mutation

scientific article

Secretion of high amounts of hepatocyte growth factor is a characteristic feature of cancer-associated fibroblasts with EGFR-TKI resistance-promoting phenotype: A study of 18 cases of cancer-associated fibroblasts

scientific article published on 24 July 2019

Spatiotemporal characteristics of fibroblasts-dependent cancer cell invasion

scientific article published on 23 November 2018

The difference in Ezrin-pAkt signaling axis between lepidic and papillary predominant invasive adenocarcinomas of the lung

scientific article published on 08 April 2016

Tumor promoting effect of podoplanin-positive fibroblasts is mediated by enhanced RhoA activity

scientific article published on 7 May 2012

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