List of works - Hiroyuki Mano

A hyperactive RelA/p65-hexokinase 2 signaling axis drives primary central nervous system lymphoma

scientific article published on 16 October 2020

A method of high-throughput functional evaluation of EGFR gene variants of unknown significance in cancer.

scientific article published in November 2017

Characterization of the large‐scale Japanese patient‐derived xenograft (J‐PDX) library

scientific article published on 24 March 2021

Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens

scientific article published on 05 March 2019

Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer

scientific article published on 16 July 2021

Development of an optimal protocol for molecular profiling of tumor cells in pleural effusions at single-cell level

scientific article published on 02 April 2021

Differential regulation of CpG island methylation within divergent and unidirectional promoters in colorectal cancer

scientific article published on 02 March 2019

Fusion kinases identified by genomic analyses of sporadic microsatellite instability-high colorectal cancers

scientific article published on 02 October 2018

Genomic profiles of colorectal carcinoma with liver metastases and newly identified fusion genes

scientific article published on 30 July 2019

High-Throughput Functional Evaluation of Variants of Unknown Significance in

scientific article published on 02 July 2018

High-throughput functional evaluation of BRCA2 variants of unknown significance

scientific article published on 22 May 2020

Identification of candidates for driver oncogenes in scirrhous-type gastric cancer cell lines

scientific article published on 15 July 2019

Identification of novel prognostic and predictive biomarkers in salivary duct carcinoma via comprehensive molecular profiling

scientific article published in 2022

KRAS mutations in uterine endometrium are associated with gravidity and parity

scientific article published on 11 May 2020

MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples

scientific article published on 15 December 2021

Multicenter phase 1/2 Trial of napabucasin and pembrolizumab in patients with metastatic colorectal cancer (EPOC1503/SCOOP Trial)

scientific article published on 21 July 2020

Small lung tumor biopsy samples are feasible for high quality targeted next generation sequencing

scientific article published on 21 June 2019

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

scientific article published on 31 August 2020

Transcript-targeted analysis reveals isoform alterations and double-hop fusions in breast cancer

scientific article published on 22 November 2021

List of works by Hiroyuki Mano