List of works - Hiroyuki Osada

A new peptaibol, RK-026A, from the soil fungus Trichoderma sp. RK10-F026 by culture condition-dependent screening ⬇️

A novel GSK3 inhibitor that promotes self-renewal in mouse embryonic stem cells

scientific article published on 08 July 2020

A small-molecule ligand of valosin-containing protein/p97 inhibits cancer cell-accelerated fibroblast migration

scientific article published on 04 January 2019

Abscisic Acid Derivatives with Different Alkyl Chain Lengths Activate Distinct Abscisic Acid Receptor Subfamilies

scientific article published on 09 September 2019

An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s

scientific article published on 02 December 2019

Aturanosides A and B, Glycosylated Anthraquinones with Antiangiogenic Activity from a Soil-Derived Streptomyces Species

scientific article published on 12 September 2018

Biosynthesis and Structure-Activity Relationship Studies of Okaramines That Target Insect Glutamate-Gated Chloride Channels

scientific article published on 31 January 2018

Biosynthetic gene cluster identification and biological activity of lucilactaene from Fusarium sp. RK97-94 ⬇️

scientific article published on 11 February 2020

Catalytic Enantioselective Synthesis of a Pyrrolizidine-Alkaloid-Inspired Compound Collection with Antiplasmodial Activity

scientific article published on 20 February 2018

Chemical reversal of abnormalities in cells carrying mitochondrial DNA mutations

scientific article published on 09 November 2020

Control of the Stereochemical Course of [4+2] Cycloaddition during trans-Decalin Formation by Fsa2-Family Enzymes

scientific article published on 04 July 2018

Development of Mirror-Image Screening Systems for XIAP BIR3 Domain Inhibitors

scientific article published on 17 April 2019

Development of a Terpenoid-Production Platform in Streptomyces reveromyceticus SN-593.

scientific article published on 11 October 2017

Discovery and applications of nucleoside antibiotics beyond polyoxin

scientific article published on 25 September 2019

Discovery of small-molecule modulator of heterotrimeric Gi-protein by integrated phenotypic profiling and chemical proteomics

scientific article published on 31 August 2020

Heterologous Expression of the Biosynthetic Gene Cluster for Verticilactam and Identification of Analogues

scientific article published on 20 November 2020

Hitoyol A and B, Two Norsesquiterpenoids from the Basidiomycete Coprinopsis cinerea.

scientific article published on 20 July 2017

Identification and Characterization of Small Molecule Compounds That Modulate Trichothecene Production by Fusarium graminearum

scientific article published on 26 March 2018

Identification of a Selective RelA Inhibitor Based on DSE-FRET Screening Methods

scientific article published on 30 November 2020

Identification of the kinanthraquinone biosynthetic gene cluster by expression of an atypical response regulator ⬇️

scientific article published on 6 February 2021

Induction of secondary metabolite production by hygromycin B and identification of the 1233A biosynthetic gene cluster with a self-resistance gene

scientific article published on 05 March 2020

Inhibition of mitochondrial complex I by the novel compound FSL0260 enhances high salinity-stress tolerance in Arabidopsis thaliana

scientific article published on 26 May 2020

Mechanism of Action of Prethioviridamide, an Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptide with a Polythioamide Structure

scientific article published on 31 July 2019

Octaminomycins A and B, Cyclic Octadepsipeptides Active against Plasmodium falciparum.

scientific article

Oxicam-type non-steroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway

scientific article published on 15 December 2021

Pentaminomycins A and B, Hydroxyarginine-Containing Cyclic Pentapeptides from Streptomyces sp. RK88-1441.

scientific article published on 7 March 2018

Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock

scientific article published on 07 October 2021

Productivity and bioactivity of enokipodins A-D of Flammulina rossica and Flammulina velutipes

scientific article published on 16 January 2020

Regulatory Mechanism of Mycotoxin Tenuazonic Acid Production in Pyricularia oryzae.

scientific article published on 18 August 2017

Special issue: Nucleoside antibiotics, polyoxin and beyond

scientific article published on 27 November 2019

Synthesis of Grb2 SH2 Domain Proteins for Mirror-Image Screening Systems.