List of works - Alexandre Alexakis

1,2-Sulfone rearrangement in organocatalytic reactions

scientific article published on 07 January 2011

1,4-Dichloro- and 1,4-dibromo-2-butenes as substrates for Cu-catalyzed asymmetric allylic substitution

scientific article published on 01 January 2007

Access to high levels of molecular complexity by one-pot iridium/enamine asymmetric catalysis

scientific article published on 03 February 2011

Asymmetric Bromine–Lithium Exchange: Application toward the Synthesis of Natural Product ⬇️

scientific article published on 06 August 2013

Asymmetric Michael addition of alpha-hydroxyketones to nitroolefins catalyzed by chiral diamine

scientific article published on 01 July 2003

Asymmetric addition of alpha-hetero-disubstituted aldehydes to vinyl sulfones; formation of highly functionalized tetrasubstituted carbon centres

scientific article published on 16 April 2010

Asymmetric bromine-lithium exchange: on the importance of both the diamine ligand and the organolithium reagent

scientific article published on 01 December 2015

Asymmetric conjugate addition to α-substituted enones/enolate trapping.

scientific article

Asymmetric organocatalytic 1,6-conjugate addition of aldehydes to dienic sulfones

scientific article published on 28 April 2011

Biphenol-based phosphoramidite ligands for the enantioselective copper-catalyzed conjugate addition of diethylzinc

scientific article published on 01 August 2004

Conformationally stabilized catalysts by fluorine insertion: tool for enantioselectivity improvement

scientific article published on 31 October 2011

Copper(I) thiolate catalysts in asymmetric conjugate addition reactions

scientific article published on 01 June 2004

Copper-Catalyzed Asymmetric 1,4-Addition of Alkenyl Alanes to N-Substituted-2-3-dehydro-4-piperidones ⬇️

scientific article published on March 15, 2012

Copper-Catalyzed Asymmetric Conjugate Addition of Alkenyl- and Alkylalanes to α,β-Unsaturated Lactams ⬇️

scientific article published on January 29, 2013

Copper-Catalyzed Enantioselective Synthesis of Axially Chiral Allenes ⬇️

scientific article published on November 12, 2012

Copper-catalysed ring opening of polycyclic meso-hydrazines with trialkylaluminium reagents and SimplePhos ligands

scientific article published on 01 February 2010

Copper-catalyzed Asymmetric Conjugate Addition to Challenging Michael Acceptors and Synthesis of Relevant Target Molecules ⬇️

scientific article published on 01 January 2012

Copper-catalyzed asymmetric conjugate addition of trialkylaluminium reagents to trisubstituted enones: construction of chiral quaternary centers

scientific article published on 01 January 2007

Copper-catalyzed asymmetric conjugate addition with chiral SimplePhos ligands

scientific article published on 01 October 2009

Copper-catalyzed enantioselective 1,4-addition to alpha,beta-unsaturated aldehydes

scientific article published on 01 May 2010

Copper-catalyzed propargylic substitution of dichloro substrates: enantioselective synthesis of trisubstituted allenes and formation of propargylic quaternary stereogenic centers

scientific article published on 19 October 2014

Creation of Highly Congested Quaternary Centers via Cu-catalyzed Conjugate Addition of Alkenyl Alanates to β-Substituted Cyclic Enones ⬇️

scientific article published on March 18, 2013

Diamine-catalyzed asymmetric Michael additions of aldehydes and ketones to nitrostyrene

scientific article published on 01 October 2002

Direct Trapping of Sterically Encumbered Aluminum Enolates ⬇️

scientific article published on April 22, 2013

Diversity-oriented synthesis towards conceptually new highly modular aminal-pyrrolidine organocatalysts

scientific article published on 01 January 2008

Domino asymmetric conjugate addition-conjugate addition

scientific article published on 24 March 2014

Dynamic kinetic asymmetric transformation in copper catalyzed allylic alkylation

scientific article published on 04 June 2009

Enantioselective 1,6-Conjugate Addition to Cyclic Dienones Catalyzed by the Cu−DiPPAM Complex ⬇️

scientific article published on 01 October 2010

Enantioselective 1,6-conjugate addition of dialkylzinc reagents to acyclic dienones catalyzed by Cu-DiPPAM complex-extension to asymmetric sequential 1,6/1,4-conjugate addition

scientific article published on 13 September 2013

Enantioselective and regiodivergent copper-catalyzed conjugate addition of trialkylaluminium reagents to extended nitro-Michael acceptors

scientific article published on 01 June 2010

Enantioselective catalytic fluorinative aza-semipinacol rearrangement

scientific article published on 12 September 2014

Enantioselective halogenative semi-pinacol rearrangement: a stereodivergent reaction on a racemic mixture

scientific article published in November 2014

Enantioselective halogenative semi-pinacol rearrangement: extension of substrate scope and mechanistic investigations

scientific article published on 25 February 2015

Enantioselective iridium-catalyzed allylic arylation

scientific article published on 01 January 2009

Enantioselective one-pot organocatalytic Michael addition/gold-catalyzed tandem acetalization/cyclization

scientific article

Enantioselective organocatalytic conjugate addition of aldehydes to nitrodienes

scientific article published on 11 September 2008

Enantioselective organocatalytic conjugate addition of aldehydes to vinyl sulfones and vinyl phosphonates as challenging Michael acceptors

scientific article published in January 2009

Enantioselective organocatalytic conjugate addition of alpha-aminoketone to nitroolefins

scientific article published on 28 August 2008

Enantioselective organocatalytic fluorination-induced Wagner-Meerwein rearrangement

scientific article

Enantioselective organocatalytic iodination-initiated Wagner-Meerwein rearrangement

scientific article published on 06 November 2013

Enantio‐ and Regioselective Conjugate Addition of Organometallic Reagents to Linear Polyconjugated Nitroolefins ⬇️

scientific article published on July 12, 2013

First enantioselective organocatalytic conjugate addition of aldehydes to vinyl phosphonates

scientific article published on 23 August 2007

Formation of Quaternary Stereogenic Centers by NHC–Cu‐Catalyzed Asymmetric Conjugate Addition Reactions with Grignard Reagents on Polyconjugated Cyclic Enones ⬇️

scientific article published on June 11, 2012

Formation of contiguous quaternary and tertiary stereocenters by sequential asymmetric conjugate addition of grignard reagents to 2-substituted enones and mg-enolate trapping

scientific article published on 27 April 2015

High diversity on simple substrates: 1,4-dihalo-2-butenes and other difunctionalized allylic halides for copper-catalyzed S(N)2' reactions

scientific article

Highly Diastereo- and Enantioselective Organocatalytic Domino Michael/Aldol Reaction of Acyclic 3-Halogeno-1,2-Diones to α,β-Unsaturated Aldehydes ⬇️

scientific article published on April 22, 2013

Highly Enantioselective and Regioselective Copper-Catalyzed 1,4 Addition of Grignard Reagents to Cyclic Enynones ⬇️

scientific article published on February 23, 2011

Highly enantioselective direct vinylogous Michael addition of γ-butenolide to enals

scientific article published on 14 February 2011

Highly enantioselective organocascade intermolecular iminium/enamine Michael addition on enals

scientific article published on 23 May 2011

Identification of a valuable kinetic process in copper-catalyzed asymmetric allylic alkylation

scientific article published on January 21, 2011

Iridium-catalyzed asymmetric allylic substitution with aryl zinc reagents

scientific article published on 19 July 2007

Kinetic study of various phosphoramidite ligands in the iridium-catalyzed allylic substitution

scientific article published on 01 April 2005

N-Heterocyclic Carbene-Catalyzed Annulation of α-Cyano-1,4-diketones with Ynals ⬇️

scientific article published on September 12, 2012

New Experimental Conditions for Tandem hydroalumination/Cu-Catalyzed Asymmetric Conjugate Additions to β-Substituted Cyclic Enones ⬇️

scientific article published on May 18, 2011

On the use of phosphoramidite ligands in copper-catalyzed asymmetric transformations with trialkylaluminum reagents

scientific article published on 01 August 2006

Organic Chemistry à la Genevoise.

scientific article published in December 2009

Organocatalytic addition on 1,2-bis(sulfone)vinylenes leading to an unprecedented rearrangement

scientific article published on 01 October 2009

Organocatalytic asymmetric annulation of 1,3-bis(alkoxycarbonyl)buta-1,3-dienes and aldehydes

scientific article published on 03 June 2013

Phosphoramidite ligands in iridium-catalyzed allylic substitution

scientific article published on 01 April 2006

Regiodivergent 1,4 versus 1,6 asymmetric copper-catalyzed conjugate addition

scientific article published on 01 January 2008

Rhodium and copper-catalyzed asymmetric conjugate addition of alkenyl nucleophiles ⬇️

scientific article published on December 25, 2012

Rhodium‐Catalyzed Asymmetric 1,4‐Addition of Aryl Alanes to Trisubstituted Enones: Binap as an Effective Ligand in the Formation of Quaternary Stereocenters ⬇️

scientific article published on October 11, 2010

Significant Asymmetric Amplification in Enantioselective Cu/DiPPAM-catalyzed 1,6- and 1,4-Conjugate Additions of Diethylzinc to (Di)enones ⬇️

scientific article published on June 28, 2012

SimplePhos monodentate ligands: synthesis and application in copper-catalyzed reactions

scientific article published on 01 January 2007

Very efficient phosphoramidite ligand for asymmetric iridium-catalyzed allylic alkylation

scientific article published on 01 September 2004

beta-Disubstituted allylic chlorides: substrates for the Cu-catalyzed asymmetric SN2' reaction

scientific article published on 01 September 2006

List of works by Alexandre Alexakis

1,2-Sulfone rearrangement in organocatalytic reactions

1,4-Dichloro- and 1,4-dibromo-2-butenes as substrates for Cu-catalyzed asymmetric allylic substitution

Access to high levels of molecular complexity by one-pot iridium/enamine asymmetric catalysis

Asymmetric Bromine–Lithium Exchange: Application toward the Synthesis of Natural Product ⬇️

Asymmetric Michael addition of alpha-hydroxyketones to nitroolefins catalyzed by chiral diamine

Asymmetric addition of alpha-hetero-disubstituted aldehydes to vinyl sulfones; formation of highly functionalized tetrasubstituted carbon centres

Asymmetric bromine-lithium exchange: on the importance of both the diamine ligand and the organolithium reagent

Asymmetric conjugate addition to α-substituted enones/enolate trapping.

Asymmetric organocatalytic 1,6-conjugate addition of aldehydes to dienic sulfones

Biphenol-based phosphoramidite ligands for the enantioselective copper-catalyzed conjugate addition of diethylzinc

Conformationally stabilized catalysts by fluorine insertion: tool for enantioselectivity improvement

Copper(I) thiolate catalysts in asymmetric conjugate addition reactions

Copper-Catalyzed Asymmetric 1,4-Addition of Alkenyl Alanes to N-Substituted-2-3-dehydro-4-piperidones ⬇️

Copper-Catalyzed Asymmetric Conjugate Addition of Alkenyl- and Alkylalanes to α,β-Unsaturated Lactams ⬇️

Copper-Catalyzed Enantioselective Synthesis of Axially Chiral Allenes ⬇️

Copper-catalysed ring opening of polycyclic meso-hydrazines with trialkylaluminium reagents and SimplePhos ligands

Copper-catalyzed Asymmetric Conjugate Addition to Challenging Michael Acceptors and Synthesis of Relevant Target Molecules ⬇️

Copper-catalyzed asymmetric conjugate addition of trialkylaluminium reagents to trisubstituted enones: construction of chiral quaternary centers

Copper-catalyzed asymmetric conjugate addition with chiral SimplePhos ligands

Copper-catalyzed enantioselective 1,4-addition to alpha,beta-unsaturated aldehydes

Copper-catalyzed propargylic substitution of dichloro substrates: enantioselective synthesis of trisubstituted allenes and formation of propargylic quaternary stereogenic centers

Creation of Highly Congested Quaternary Centers via Cu-catalyzed Conjugate Addition of Alkenyl Alanates to β-Substituted Cyclic Enones ⬇️

Diamine-catalyzed asymmetric Michael additions of aldehydes and ketones to nitrostyrene

Direct Trapping of Sterically Encumbered Aluminum Enolates ⬇️

Diversity-oriented synthesis towards conceptually new highly modular aminal-pyrrolidine organocatalysts

Domino asymmetric conjugate addition-conjugate addition

Dynamic kinetic asymmetric transformation in copper catalyzed allylic alkylation

Enantioselective 1,6-Conjugate Addition to Cyclic Dienones Catalyzed by the Cu−DiPPAM Complex ⬇️

Enantioselective 1,6-conjugate addition of dialkylzinc reagents to acyclic dienones catalyzed by Cu-DiPPAM complex-extension to asymmetric sequential 1,6/1,4-conjugate addition

Enantioselective and regiodivergent copper-catalyzed conjugate addition of trialkylaluminium reagents to extended nitro-Michael acceptors

Enantioselective catalytic fluorinative aza-semipinacol rearrangement

Enantioselective halogenative semi-pinacol rearrangement: a stereodivergent reaction on a racemic mixture

Enantioselective halogenative semi-pinacol rearrangement: extension of substrate scope and mechanistic investigations

Enantioselective iridium-catalyzed allylic arylation

Enantioselective one-pot organocatalytic Michael addition/gold-catalyzed tandem acetalization/cyclization

Enantioselective organocatalytic conjugate addition of aldehydes to nitrodienes

Enantioselective organocatalytic conjugate addition of aldehydes to vinyl sulfones and vinyl phosphonates as challenging Michael acceptors

Enantioselective organocatalytic conjugate addition of alpha-aminoketone to nitroolefins

Enantioselective organocatalytic fluorination-induced Wagner-Meerwein rearrangement

Enantioselective organocatalytic iodination-initiated Wagner-Meerwein rearrangement

Enantio‐ and Regioselective Conjugate Addition of Organometallic Reagents to Linear Polyconjugated Nitroolefins ⬇️

First enantioselective organocatalytic conjugate addition of aldehydes to vinyl phosphonates

Formation of Quaternary Stereogenic Centers by NHC–Cu‐Catalyzed Asymmetric Conjugate Addition Reactions with Grignard Reagents on Polyconjugated Cyclic Enones ⬇️

Formation of contiguous quaternary and tertiary stereocenters by sequential asymmetric conjugate addition of grignard reagents to 2-substituted enones and mg-enolate trapping

High diversity on simple substrates: 1,4-dihalo-2-butenes and other difunctionalized allylic halides for copper-catalyzed S(N)2' reactions

Highly Diastereo- and Enantioselective Organocatalytic Domino Michael/Aldol Reaction of Acyclic 3-Halogeno-1,2-Diones to α,β-Unsaturated Aldehydes ⬇️

Highly Enantioselective and Regioselective Copper-Catalyzed 1,4 Addition of Grignard Reagents to Cyclic Enynones ⬇️

Highly enantioselective direct vinylogous Michael addition of γ-butenolide to enals

Highly enantioselective organocascade intermolecular iminium/enamine Michael addition on enals

Identification of a valuable kinetic process in copper-catalyzed asymmetric allylic alkylation

Iridium-catalyzed asymmetric allylic substitution with aryl zinc reagents

Kinetic study of various phosphoramidite ligands in the iridium-catalyzed allylic substitution

N-Heterocyclic Carbene-Catalyzed Annulation of α-Cyano-1,4-diketones with Ynals ⬇️

New Experimental Conditions for Tandem hydroalumination/Cu-Catalyzed Asymmetric Conjugate Additions to β-Substituted Cyclic Enones ⬇️

On the use of phosphoramidite ligands in copper-catalyzed asymmetric transformations with trialkylaluminum reagents

Organic Chemistry à la Genevoise.

Organocatalytic addition on 1,2-bis(sulfone)vinylenes leading to an unprecedented rearrangement

Organocatalytic asymmetric annulation of 1,3-bis(alkoxycarbonyl)buta-1,3-dienes and aldehydes

Phosphoramidite ligands in iridium-catalyzed allylic substitution

Regiodivergent 1,4 versus 1,6 asymmetric copper-catalyzed conjugate addition

Rhodium and copper-catalyzed asymmetric conjugate addition of alkenyl nucleophiles ⬇️

Rhodium‐Catalyzed Asymmetric 1,4‐Addition of Aryl Alanes to Trisubstituted Enones: Binap as an Effective Ligand in the Formation of Quaternary Stereocenters ⬇️

Significant Asymmetric Amplification in Enantioselective Cu/DiPPAM-catalyzed 1,6- and 1,4-Conjugate Additions of Diethylzinc to (Di)enones ⬇️

SimplePhos monodentate ligands: synthesis and application in copper-catalyzed reactions

Very efficient phosphoramidite ligand for asymmetric iridium-catalyzed allylic alkylation

beta-Disubstituted allylic chlorides: substrates for the Cu-catalyzed asymmetric SN2' reaction