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List of works by Minoru Toyota

A novel correlation between LINE-1 hypomethylation and the malignancy of gastrointestinal stromal tumors

scientific article published on 26 October 2010

A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth

scientific article published on 23 June 2009

A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma

scientific article published on 10 January 2012

A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells

scientific article

Aberrant DNA methylation associated with aggressiveness of gastrointestinal stromal tumour

scientific article published on June 27, 2011

Aberrant methylation of RASGRF1 is associated with an epigenetic field defect and increased risk of gastric cancer.

scientific article

Activation of the ribosomal protein L13 gene in human gastrointestinal cancer.

scientific article

Cancer epigenomics: implications of DNA methylation in personalized cancer therapy

scientific article published on 19 February 2009

Comparative genome analysis identifies the vitamin D receptor gene as a direct target of p53-mediated transcriptional activation.

scientific article published on May 2006

Correction: Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma

scientific article

Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer

scientific article published on 29 February 2008

DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer

scientific article

DNA methylation and cancer pathways in gastrointestinal tumors

scientific article published on December 2008

DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae

scientific article

Epigenetic alteration of DNA in mucosal wash fluid predicts invasiveness of colorectal tumors.

scientific article published in May 2011

Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.

scientific article

Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.

scientific article

Epigenetics in gastroenterological cancer and prospects for translational research.

scientific article published on September 2007

Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.

scientific article published on 3 August 2007

Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma

scientific article

Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus

scientific article published in April 2006

Genome-wide analysis of DNA methylation identifies novel cancer-related genes in hepatocellular carcinoma.

scientific article

Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer.

scientific article

Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.

scientific article

Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma.

scientific article

Haploinsufficiency in multiploid colorectal cancer

scientific article published on 01 July 2005

Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models

scientific article

IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype

scientific article

Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer

scientific article published on January 2007

Identification of flotillin-2, a major protein on lipid rafts, as a novel target of p53 family members

scientific article

Inflammation-related aberrant patterns of DNA methylation: detection and role in epigenetic deregulation of cancer cell transcriptome.

scientific article

Integrated analysis of genetic and epigenetic alterations in cancer

scientific article published on December 2009

Interferon-α/β and anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo

scientific article (publication date: 9 May 2011)

LINE-1 hypomethylation is associated with increased CpG island methylation in Helicobacter pylori-related enlarged-fold gastritis.

scientific article

Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect

scientific article published on 5 October 2010

Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype.

scientific article published on 17 September 2012

PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer.

scientific article published on August 2007

Role of DNA methylation in the development of diffuse-type gastric cancer

scientific article published on 27 January 2011

Small interfering RNA-induced CHFR silencing sensitizes oral squamous cell cancer cells to microtubule inhibitors.

scientific article published on 6 July 2005

The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents

scientific article

Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors

scientific article published on 18 January 2012

[DNA methylation and carcinogenesis].

scientific article

[Epigenetic alterations in cancer].

scientific article

[Gene mutation and DNA methylation in non-hereditary colon neoplasms]

scientific article published on 01 February 2007

p53 family members regulate the expression of the apolipoprotein D gene.

scientific article

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