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List of works by Marija Tadin-Strapps

A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice

scientific article published on 19 August 2008

A recurrent intragenic deletion in the desmoglein 4 gene underlies localized autosomal recessive hypotrichosis

scientific article published on 01 September 2004

Alterations in the hepatic transcriptional landscape after RNAi mediated ApoB silencing in cynomolgus monkeys

scientific article

ApoB siRNA‐induced Liver Steatosis is Resistant to Clearance by the Loss of Fatty Acid Transport Protein 5 (Fatp5) ⬇️

scientific article published on August 9, 2011

Attenuation of Slc27a5 Gene Expression Followed by LC–MS Measurement of Bile Acid Reconjugation Using Metabolomics and a Stable Isotope Tracer Strategy ⬇️

scientific article published on August 26, 2011

DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates

scientific article published on 20 April 2018

Development of lipoprotein(a) siRNAs for mechanism of action studies in non-human primate models of atherosclerosis

scientific article

Discovering metabolic disease gene interactions by correlated effects on cellular morphology

article

Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey

scientific article published on 05 October 2016

Factor XII full and partial null in rat confers robust antithrombotic efficacy with no bleeding

scientific article published in December 2015

Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9 ⬇️

scientific article published on January 24, 2011

Mutations in the cholesterol transporter gene ABCA5 are associated with excessive hair overgrowth

scientific article

Position effect on FGF13 associated with X-linked congenital generalized hypertrichosis.

scientific article

Preclinical and translational evaluation of coagulation factor IXa as a novel therapeutic target

scientific article published on 15 January 2016

Proof-of-concept Studies for siRNA-mediated Gene Silencing for Coagulation Factors in Rat and Rabbit

scientific article published on 27 January 2015

Rescue of Mtp siRNA-induced hepatic steatosis by DGAT2 siRNA silencing

scientific article published on 21 February 2012

Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth

scientific article

TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation

scientific article published on 13 February 2017

Targeting of hepatic angiotensinogen using chemically modified siRNAs results in significant and sustained blood pressure lowering in a rat model of hypertension

scientific article published on 12 December 2013

Titrating haemophilia B phenotypes using siRNA strategy: evidence that antithrombotic activity is separated from bleeding liability

scientific article published on 19 March 2015

siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids

scientific article

siRNA-mediated inhibition of SREBP cleavage-activating protein reduces dyslipidemia in spontaneously dysmetabolic rhesus monkeys

scientific article published on 06 March 2017

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