List of works - Clemens M F Dirven

A microcosting study of microsurgery, LINAC radiosurgery, and gamma knife radiosurgery in meningioma patients

scientific article

A randomised trial of high and low pressure level settings on an adjustable ventriculoperitoneal shunt valve for idiopathic normal pressure hydrocephalus: results of the Dutch evaluation programme Strata shunt (DEPSS) trial

scientific article

ABT-888 enhances cytotoxic effects of temozolomide independent of MGMT status in serum free cultured glioma cells.

scientific article published on 26 February 2015

AdDelta24 and the p53-expressing variant AdDelta24-p53 achieve potent anti-tumor activity in glioma when combined with radiotherapy.

scientific article published on December 2007

Anatomical differences determine distribution of adenovirus after convection-enhanced delivery to the rat brain

scientific article

Association Between Vascular Anatomy and Posterior Communicating Artery Aneurysms

scientific article published on 11 June 2015

Candidate genes on chromosome 9q33-34 involved in the progression of childhood ependymomas.

scientific article

Clinical factors associated with outcome in chronic subdural hematoma: a retrospective cohort study of patients on preoperative corticosteroid therapy

scientific article published in April 2012

Contemporary frameless intracranial biopsy techniques: Might variation in safety and efficacy be expected?

scientific article

Corticosteroid treatment compared with surgery in chronic subdural hematoma: a systematic review and meta-analysis

scientific article published on 10 April 2019

Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging

scientific article

Delineation of brain AVMs on MR-Angiography for the purpose of stereotactic radiosurgery

scientific article

Dexamethasone therapy versus surgery for chronic subdural haematoma (DECSA trial): study protocol for a randomised controlled trial

scientific article published on 20 October 2018

Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology

scientific article published on July 2015

Differential effects of combined Ad5- delta 24RGD and radiation therapy in in vitro versus in vivo models of malignant glioma.

scientific article published on December 2007

Does early resection of presumed low-grade glioma improve survival? A clinical perspective.

scientific article

Effect of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant in human cranial arteries

scientific article published on 26 March 2010

Efficient and selective gene transfer into primary human brain tumors by using single-chain antibody-targeted adenoviral vectors with native tropism abolished

scientific article published on March 2002

Fusiform Aneurysms Are Associated with Aortic Root Dilatation in Patients with Subarachnoid Hemorrhage

scientific article published on 13 July 2015

Gene delivery into malignant glioma by infectivity-enhanced adenovirus: in vivo versus in vitro models

scientific article published on 23 May 2007

Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma.

scientific article published on 17 March 2016

Glioma surgery in eloquent areas: can we preserve cognition?

scientific article

Glut1/SLC2A1 is crucial for the development of the blood‐brain barrier in vivo ⬇️

scientific article published on December 1, 2010

HeNe Laser (633 nm)-Coupled Confocal Microscope Allows Simulating Magnetic Resonance Imaging/Computed Tomography Scan of the Brain and Eye: A Noninvasive Optical Approach Applicable to Small Laboratory Animals ⬇️

scientific article published on June 1, 2011

Laser speckle imaging identification of increases in cortical microcirculatory blood flow induced by motor activity during awake craniotomy.

scientific article

Locally-delivered T-cell-derived cellular vehicles efficiently track and deliver adenovirus delta24-RGD to infiltrating glioma

scientific article

Magnetic Resonance Imaging-Based Assessment of Gadolinium-Conjugated Diethylenetriamine Penta-Acetic Acid Test-Infusion in Detecting Dysfunction of Convection-Enhanced Delivery Catheters

scientific article

Malignant Glioma In Vitro Models: On the Utilization of Stem-like Cells

scientific article published on 13 August 2016

Objective determination of the oncolytic potency of conditionally-replicating adenoviruses using mathematical modeling.

scientific article published on July 2010

Oncolytic activity of p53-expressing conditionally replicative adenovirus AdDelta24-p53 against human malignant glioma

scientific article published on August 2004

Pathophysiology and Nonsurgical Treatment of Chronic Subdural Hematoma: From Past to Present to Future

scientific article published on 14 May 2018

Pituitary Dysfunction After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis

scientific article

Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.

scientific article published in October 2002

Raman spectroscopy for cancer detection and cancer surgery guidance: translation to the clinics

scientific article

Serum-free culture success of glial tumors is related to specific molecular profiles and expression of extracellular matrix-associated gene modules.

scientific article published on 17 September 2013

Sitimagene ceradenovec: a gene-based drug for the treatment of operable high-grade glioma

scientific article

Spontaneous regression of brain arteriovenous malformations--a clinical study and a systematic review of the literature

scientific article

Stereotactic radiosurgery for brain AVMs: role of interobserver variation in target definition on digital subtraction angiography

scientific article published on May 2005

The Bcl-2 inhibitor Obatoclax overcomes resistance to histone deacetylase inhibitors SAHA and LBH589 as radiosensitizers in patient-derived glioblastoma stem-like cells.

scientific article published on November 2014

The Flower Petal Training System in Microsurgery: Validation of a Training Model Using a Randomized Controlled Trial

scientific article published on 01 December 2019

The HDAC Inhibitors Scriptaid and LBH589 Combined with the Oncolytic Virus Delta24-RGD Exert Enhanced Anti-Tumor Efficacy in Patient-Derived Glioblastoma Cells

scientific article published on 18 May 2015

The Sequence of Delta24-RGD and TMZ Administration in Malignant Glioma Affects the Role of CD8+T Cell Anti-tumor Activity.

scientific article

The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma

scientific article published on April 2006

The in vivo therapeutic efficacy of the oncolytic adenovirus Delta24-RGD is mediated by tumor-specific immunity

scientific article

The incidence of postoperative thromboembolic complications following surgical resection of intracranial meningioma. A retrospective study of a large single center patient cohort.

scientific article

The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitro

scientific article published in November 2002

The therapeutic efficacy of the oncolytic virus Delta24-RGD in a murine glioma model depends primarily on antitumor immunity.

scientific article published on October 2014

Therapeutic concentrations of anti-epileptic drugs do not inhibit the activity of the oncolytic adenovirus Delta24-RGD in malignant glioma

scientific article published on March 2013

Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.

scientific article published on October 2005

Towards improving the safety and diagnostic yield of stereotactic biopsy in a single centre

scientific article

List of works by Clemens M F Dirven

A microcosting study of microsurgery, LINAC radiosurgery, and gamma knife radiosurgery in meningioma patients

A randomised trial of high and low pressure level settings on an adjustable ventriculoperitoneal shunt valve for idiopathic normal pressure hydrocephalus: results of the Dutch evaluation programme Strata shunt (DEPSS) trial

ABT-888 enhances cytotoxic effects of temozolomide independent of MGMT status in serum free cultured glioma cells.

AdDelta24 and the p53-expressing variant AdDelta24-p53 achieve potent anti-tumor activity in glioma when combined with radiotherapy.

Anatomical differences determine distribution of adenovirus after convection-enhanced delivery to the rat brain

Association Between Vascular Anatomy and Posterior Communicating Artery Aneurysms

Candidate genes on chromosome 9q33-34 involved in the progression of childhood ependymomas.

Clinical factors associated with outcome in chronic subdural hematoma: a retrospective cohort study of patients on preoperative corticosteroid therapy

Contemporary frameless intracranial biopsy techniques: Might variation in safety and efficacy be expected?

Corticosteroid treatment compared with surgery in chronic subdural hematoma: a systematic review and meta-analysis

Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging

Delineation of brain AVMs on MR-Angiography for the purpose of stereotactic radiosurgery

Dexamethasone therapy versus surgery for chronic subdural haematoma (DECSA trial): study protocol for a randomised controlled trial

Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology

Differential effects of combined Ad5- delta 24RGD and radiation therapy in in vitro versus in vivo models of malignant glioma.

Does early resection of presumed low-grade glioma improve survival? A clinical perspective.

Effect of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant in human cranial arteries

Efficient and selective gene transfer into primary human brain tumors by using single-chain antibody-targeted adenoviral vectors with native tropism abolished

Fusiform Aneurysms Are Associated with Aortic Root Dilatation in Patients with Subarachnoid Hemorrhage

Gene delivery into malignant glioma by infectivity-enhanced adenovirus: in vivo versus in vitro models

Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma.

Glioma surgery in eloquent areas: can we preserve cognition?

Glut1/SLC2A1 is crucial for the development of the blood‐brain barrier in vivo ⬇️

HeNe Laser (633 nm)-Coupled Confocal Microscope Allows Simulating Magnetic Resonance Imaging/Computed Tomography Scan of the Brain and Eye: A Noninvasive Optical Approach Applicable to Small Laboratory Animals ⬇️

Laser speckle imaging identification of increases in cortical microcirculatory blood flow induced by motor activity during awake craniotomy.

Locally-delivered T-cell-derived cellular vehicles efficiently track and deliver adenovirus delta24-RGD to infiltrating glioma

Magnetic Resonance Imaging-Based Assessment of Gadolinium-Conjugated Diethylenetriamine Penta-Acetic Acid Test-Infusion in Detecting Dysfunction of Convection-Enhanced Delivery Catheters

Malignant Glioma In Vitro Models: On the Utilization of Stem-like Cells

Objective determination of the oncolytic potency of conditionally-replicating adenoviruses using mathematical modeling.

Oncolytic activity of p53-expressing conditionally replicative adenovirus AdDelta24-p53 against human malignant glioma

Pathophysiology and Nonsurgical Treatment of Chronic Subdural Hematoma: From Past to Present to Future

Pituitary Dysfunction After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis

Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.

Raman spectroscopy for cancer detection and cancer surgery guidance: translation to the clinics

Serum-free culture success of glial tumors is related to specific molecular profiles and expression of extracellular matrix-associated gene modules.

Sitimagene ceradenovec: a gene-based drug for the treatment of operable high-grade glioma

Spontaneous regression of brain arteriovenous malformations--a clinical study and a systematic review of the literature

Stereotactic radiosurgery for brain AVMs: role of interobserver variation in target definition on digital subtraction angiography

The Bcl-2 inhibitor Obatoclax overcomes resistance to histone deacetylase inhibitors SAHA and LBH589 as radiosensitizers in patient-derived glioblastoma stem-like cells.

The Flower Petal Training System in Microsurgery: Validation of a Training Model Using a Randomized Controlled Trial

The HDAC Inhibitors Scriptaid and LBH589 Combined with the Oncolytic Virus Delta24-RGD Exert Enhanced Anti-Tumor Efficacy in Patient-Derived Glioblastoma Cells

The Sequence of Delta24-RGD and TMZ Administration in Malignant Glioma Affects the Role of CD8+T Cell Anti-tumor Activity.

The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma

The in vivo therapeutic efficacy of the oncolytic adenovirus Delta24-RGD is mediated by tumor-specific immunity

The incidence of postoperative thromboembolic complications following surgical resection of intracranial meningioma. A retrospective study of a large single center patient cohort.

The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitro

The therapeutic efficacy of the oncolytic virus Delta24-RGD in a murine glioma model depends primarily on antitumor immunity.

Therapeutic concentrations of anti-epileptic drugs do not inhibit the activity of the oncolytic adenovirus Delta24-RGD in malignant glioma

Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.

Towards improving the safety and diagnostic yield of stereotactic biopsy in a single centre