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List of works by Takaji Wakita

2',5'-Oligoadenylate synthetase-like gene highly induced by hepatitis C virus infection in human liver is inhibitory to viral replication in vitro

scientific article

A hepatitis C virus (HCV) vaccine comprising envelope glycoproteins gpE1/gpE2 derived from a single isolate elicits broad cross-genotype neutralizing antibodies in humans

scientific article

Antiviral activity of glycyrrhizin against hepatitis C virus in vitro

scientific article (publication date: 2013)

Antiviral lectins from red and blue-green algae show potent in vitro and in vivo activity against hepatitis C virus

scientific article

Arsenic Trioxide Inhibits Hepatitis C Virus RNA Replication through Modulation of the Glutathione Redox System and Oxidative Stress

scientific article (publication date: March 2009)

Biological properties of purified recombinant HCV particles with an epitope-tagged envelope

scientific article published on 23 April 2010

Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicits neutralizing antibodies against JEV and hepatitis C virus

scientific article

CD81 Expression Is Important for the Permissiveness of Huh7 Cell Clones for Heterogeneous Hepatitis C Virus Infection

scientific article (publication date: May 2007)

Candidatus Mycoplasma haemohominis in Human, Japan

scientific article published on 01 January 2020

Critical Role of Virion-Associated Cholesterol and Sphingolipid in Hepatitis C Virus Infection

scientific article

Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP).

scientific article

DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication

scientific article

De Novo Macrocyclic Peptide Inhibitors of Hepatitis B Virus Cellular Entry

scientific article published on 17 May 2018

Detection of anti-hepatitis C virus effects of interferon and ribavirin by a sensitive replicon system

scientific article

Diverse Effects of Cyclosporine on Hepatitis C Virus Strain Replication

scientific article

Dysregulation of retinoic acid receptor diminishes hepatocyte permissiveness to hepatitis B virus infection through modulation of sodium taurocholate cotransporting polypeptide (NTCP) expression

scientific article

E6AP ubiquitin ligase mediates ubiquitylation and degradation of hepatitis C virus core protein

scientific article

Ethanol Enhances Hepatitis C Virus Replication through Lipid Metabolism and Elevated NADH/NAD+

scientific article

Evaluation of Hepatitis C Virus Core Antigen Assays in Detecting Recombinant Viral Antigens of Various Genotypes

scientific article

Functional association of cellular microtubules with viral capsid assembly supports efficient hepatitis B virus replication

scientific article published on 6 September 2017

Generation of Infectious Hepatitis C Virus in Immortalized Human Hepatocytes

scientific article

Genetic variation of the IL-28B promoter affecting gene expression

scientific article

HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor

scientific article

Haplotype networks of SARS-CoV-2 infections in the Diamond Princess cruise ship outbreak

scientific article (preprint)

Hepatitis C Virus Entry Depends on Clathrin-Mediated Endocytosis

scientific article (publication date: July 2006)

Hepatitis C Virus Nonstructural 4B Protein Modulates Sterol Regulatory Element-binding Protein Signaling via the AKT Pathway

scientific article

Hepatitis C virus JFH-1 strain infection in chimpanzees is associated with low pathogenicity and emergence of an adaptive mutation

scientific article (publication date: September 2008)

Hepatitis C virus controls interferon production through PKR activation

scientific article

Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2.

scientific article

Hepatitis C virus infection of T cells inhibits proliferation and enhances fas-mediated apoptosis by down-regulating the expression of CD44 splicing variant 6.

scientific article

Hepatitis C virus-induced innate immune responses in human iPS cell-derived hepatocyte-like cells

scientific article published on 8 September 2017

Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection.

scientific article published on 04 April 2017

Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway

scientific article

Independent evolution of multi-dominant viral genome species observed in a hepatitis C virus carrier

scientific article published in 2022

Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

scientific article

Inhibitory effects on HAV IRES-mediated translation and replication by a combination of amantadine and interferon-alpha

scientific article

Inoculation of Plasmids Encoding Japanese Encephalitis Virus PrM-E Proteins with Colloidal Gold Elicits a Protective Immune Response in BALB/c Mice

scientific article (publication date: April 2003)

Interaction of Hepatitis C Virus Nonstructural Protein 5A with Core Protein Is Critical for the Production of Infectious Virus Particles

scientific article

Intragenotypic JFH1 based recombinant hepatitis C virus produces high levels of infectious particles but causes increased cell death

scientific article (publication date: 5 July 2008)

Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein

scientific article

Monitoring the Antiviral Effect of Alpha Interferon on Individual Cells

scientific article (publication date: August 2007)

NTCP and beyond: opening the door to unveil hepatitis B virus entry

scientific article

New preclinical antimalarial drugs potently inhibit hepatitis C virus genotype 1b RNA replication

scientific article (publication date: 2013)

Non-nucleoside hepatitis B virus polymerase inhibitors identified by an in vitro polymerase elongation assay

scientific article published on 25 November 2019

Nuclear localization of Japanese encephalitis virus core protein enhances viral replication

scientific article published in March 2005

Production of Infectious Hepatitis C Virus of Various Genotypes in Cell Cultures

scientific article

Production of infectious chimeric hepatitis C virus genotype 2b harboring minimal regions of JFH-1.

scientific article published on 7 December 2011

Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells

scientific article (publication date: 14 February 2006)

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

scientific article (publication date: July 2005)

Proteasomal Turnover of Hepatitis C Virus Core Protein Is Regulated by Two Distinct Mechanisms: a Ubiquitin-Dependent Mechanism and a Ubiquitin-Independent but PA28 -Dependent Mechanism

scientific article (publication date: March 2009)

Regulation of CXCL-8 (Interleukin-8) Induction by Double-Stranded RNA Signaling Pathways during Hepatitis C Virus Infection

scientific article

Replication of a hepatitis C virus replicon clone in mouse cells

scientific article (publication date: 28 October 2006)

Robust hepatitis C virus infection in vitro

scientific article

Robust production of infectious hepatitis C virus (HCV) from stably HCV cDNA-transfected human hepatoma cells

scientific article

Screening siRNAs against host glycosylation pathways to develop novel anti-viral agents against hepatitis B virus

scientific article published on 01 August 2020

Seroprevalence of trichodysplasia spinulosa-associated polyomavirus in Japan.

scientific article

Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2

scientific article

Suppression of La antigen exerts potential antiviral effects against hepatitis A virus

scientific article published in 2014

The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication

scientific article

The NS3 Helicase and NS5B-to-3'X Regions Are Important for Efficient Hepatitis C Virus Strain JFH-1 Replication in Huh7 Cells

scientific article

The lipid droplet is an important organelle for hepatitis C virus production

scientific article (publication date: September 2007)

Valosin-Containing Protein (VCP/p97) Is Required for Poliovirus Replication and Is Involved in Cellular Protein Secretion Pathway in Poliovirus Infection ⬇️

scientific article published on February 29, 2012

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