Search filters

List of works by Rolf M. Zinkernagel

"Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses

scientific article

"Viral déjà vu" elicits organ-specific immune disease independent of reactivity to self

scientific article

A Btk transgene restores the antiviral TI-2 antibody responses of xid mice in a dose-dependent fashion

scientific article published in September 1999

A biological role for the major histocompatibility antigens

scientific article

A comparison of T cell memory against the same antigen induced by virus versus intracellular bacteria.

scientific article published on August 1999

A comparison of efficacy and specificity of three NK depleting antibodies

scientific article published on 01 December 1996

A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers

scientific article

A crucial role for B cells in neuroinvasive scrapie.

scientific article published in December 1997

A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro ⬇️

scientific article published on December 1, 1997

A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8(+) T cell responses

scholarly article

A monoclonal antibody against altered LFA-1 induces proliferation and lymphokine release of cloned T cells

scientific article published on 01 February 1986

A non-retroviral RNA virus persists in DNA form ⬇️

scientific article published on November 20, 1997

A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3

scientific article published on 30 October 2011

A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria

scientific article published on 01 June 2000

A protective cytotoxic T cell response to a subdominant epitope is influenced by the stability of the MHC class I/peptide complex and the overall spectrum of viral peptides generated within infected cells

scientific article published on October 1998

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

scientific article published in April 1991

Absence of complement receptor type 3 and lymphocyte function antigen 1 causing deficient phagocyte and lymphocyte functions

scientific article published on 01 October 1988

Absence of effects of thymopentin on murine host resistance to Listeria monocytogenes

scientific article published on 01 February 1991

Activation or suppression of bactericidal activity of macrophages during a graft-versus-host reaction againstI-A andI-J-region differences, respectively ⬇️

scientific article published on January 1, 1980

Acute rejection of vascular heart allografts by perforin-deficient mice

scientific article published on 01 February 1995

Addendum: Specific cytotoxic T cells eliminate cells producing neutralizing antibodies

scientific article published in Nature

Additive effect of neutralizing antibody and antiviral drug treatment in preventing virus escape and persistence

scientific article

Adherence of pathogenic Escherichia coli to epithelial cells isolated from the intestinal mucosa of the rabbit, inhibiting effect of hyperimmune bovine colostrum and of various carbohydrates (author's transl)

scientific article published on January 1, 1975

Aggravation of viral hepatitis by platelet-derived serotonin

scientific article published on 30 May 2008

Allogeneic H-2d leads to H-2b irradiation bone marrow chimeras: a) failure to transfer chimerism adoptively and b) immune reactivity of immunocompetent lymphocytes adoptively transferred to chimeras

scientific article published on 01 May 1983

Allogeneic beta-islet cells correct diabetes and resist immune rejection

scientific article

An acquired immune suppression in mice caused by infection with lymphocytic choriomeningitis virus

scientific article published in April 1988

An easy and rapid method to screen large numbers of antibodies against internal cellular determinants

scientific article

An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses

scientific article published on October 1998

Analysis of neutralizing antibody specificities of different strains of lymphocytic choriomeningitis virus with strain-specific immune sera

scientific article published in November 1993

Analysis of the kinetics of antiviral memory T help in vivo: characterization of short-lived cross-reactive T help

scientific article published in December 1990

Antagonistic variant virus prevents wild-type virus-induced lethal immunopathology

scientific article published on October 2002

Anti-Listeria monocytogenes immunity in mu-suppressed mice: a comparison of treatment with conventional hyperimmune rabbit anti-mouse IgM and affinity-purified, monoclonal rat anti-mouse IgM.

scientific article

Anti-viral immune response of allogeneic irradiation bone marrow chimeras: cytotoxic T cell responsiveness depends upon H-2 combination and infectious agent

scientific article published in January 1984

Anti-viral protection and prevention of lymphocytic choriomeningitis or of the local footpad swelling reaction in mice by immunization with vaccinia-recombinant virus expressing LCMV-WE nucleoprotein or glycoprotein

scientific article published in March 1989

Antibodies against the two serotypes of vesicular stomatitis virus measured by enzyme-linked immunosorbent assay: immunodominance of serotype-specific determinants and induction of asymmetrically cross-reactive antibodies

scientific article published on August 1987

Antibody mediated suppression of secondary IgM response in nude mice against vesicular stomatitis virus

scientific article

Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity

scientific article published on April 1997

Antigen localization and migration in immunity and tolerance

scientific article

Antigen persistence and time of T-cell tolerization determine the efficacy of tolerization protocols for prevention of skin graft rejection

scientific article published on September 1998

Antiinfection immunity and autoimmunity.

scientific article

Antiviral B cell memory in the absence of mature follicular dendritic cell networks and classical germinal centers in TNFR1-/- mice

scientific article

Antiviral T cell competence and restriction specificity of mixed allogeneic (P1 + P2----P1) irradiation chimeras

scientific article published on 01 June 1989

Antiviral T-cell memory?

scientific article published on January 1990

Antiviral antibody responses: the two extremes of a wide spectrum

scientific article

Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide ⬇️

scientific article published on May 1, 1990

Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors ⬇️

scientific article published on August 1, 1995

Antiviral immune responses in CTLA4 transgenic mice

scientific article published in March 1997

Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies

scientific article published on 20 October 2003

Antiviral immune responses in mice deficient for both interleukin-2 and interleukin-4.

scientific article published in August 1995

Antiviral immune responses in the absence of organized lymphoid T cell zones in plt/plt mice

scientific article published in June 2002

Antiviral immune responses of mice lacking MHC class II or its associated invariant chain

scientific article published on 01 January 1996

Antiviral immunity

scientific article published on June 1997

Antiviral protection and germinal center formation, but impaired B cell memory in the absence of CD19.

scientific article published on July 1998

Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice.

scientific article published in April 1995

Antiviral protection by virus-immune cytotoxic T cells: infected target cells are lysed before infectious virus progeny is assembled ⬇️

scientific article published on March 1, 1977

Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen ⬇️

scientific article published on November 1, 1992

Aplastic Anemia Rescued by Exhaustion of Cytokine-secreting CD8+ T Cells in Persistent Infection with Lymphocytic Choriomeningitis Virus ⬇️

scientific article published on June 1, 1998

Are HIV-specific CTL responses salutary or pathogenic?

scientific article published on August 1995

Arterial inflammation and atherosclerosis

scientific article

Assessing the mechanisms that give rise to autoimmunity

scientific article published on 01 October 2000

Assessment of some genetic non-MHC differences with GVHR-induced anti-listeria activity of macrophages

scientific article published on 01 January 1982

Association of disease susceptibility to major histocompatibility antigens

scientific article published on March 1, 1979

Associations Between Major Histocompatibility Antigens and Susceptibility to Disease ⬇️

scientific article published on January 1, 1979

Astrocytes as antigen-presenting cells. Part II: Unlike H-2K-dependent cytotoxic T cells, H-2Ia-restricted T cells are only stimulated in the presence of interferon-gamma

scientific article published on 01 July 1986

B cell activation state-governed formation of germinal centers following viral infection.

scientific article published on November 2007

B cells are required for induction of T cell abnormalities in a murine retrovirus-induced immunodeficiency syndrome

scientific article

Biological role of major transplantation antigens in T cell self-recognition

scientific article

Bystander activation of cytotoxic T cells: studies on the mechanism and evaluation of in vivo significance in a transgenic mouse model

scientific article

CD4 negative mice as a model for immunodeficiency

scientific article published on 01 October 1993

CD4(+) T cell subsets during virus infection. Protective capacity depends on effector cytokine secretion and on migratory capability

scientific article

CD4+ T-Cell Induction and Effector Functions: A Comparison of Immunity against Soluble Antigens and Viral Infections

scientific article published on 01 January 1998

CD4+ T-cell-epitope escape mutant virus selected in vivo

scientific article published in July 2001

CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions

scientific article

CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity

scientific article published in December 1994

CXCR5-dependent seeding of follicular niches by B and Th cells augments antiviral B cell responses

scientific article published on 01 December 2005

Cell-Mediated Immunity to Vesicular Stomatitis Virus Infections in Mice ⬇️

scientific article published on January 1, 1978

Cell-mediated immune response to Salmonella typhimurium infection in mice: development of nonspecific bactericidal activity against Listeria monocytogenes ⬇️

scientific article published on April 1, 1976

Cell-mediated immune response to lymphocytic choriomeningitis and vaccinia virus in rats ⬇️

scientific article published on October 1, 1977

Cell-mediated immunity to hepatitis-associated antigen (HAA) demonstrated by leucocyte migration test during and after acute B hepatitis.

scientific article published in September 1973

Cell-mediated immunity to viruses in hamsters

scientific article published on May 15, 1978

Cells that express viral antigens but lack H-2 determinants are not lysed by immune thymus-derived lymphocytes but are lysed by other antiviral immune attack mechanisms ⬇️

scientific article published on October 1, 1976

Cellular Immune Recognition and the Biological Role of Major Transplantation Antigens ⬇️

scientific article published on April 1, 1997

Characteristics of the interaction in vitro between cytotoxic thymus-derived lymphocytes and target monolayers infected with lymphocytic choriomeningitis virus

scientific article published in January 1974

Characterization and Immunological Properties of Influenza A Virus Nucleoprotein (NP): Cell-associated NP Isolated from Infected Cells or Viral NP Expressed by Vaccinia Recombinant Virus do not Confer Protection

scientific article published on May 1, 1990

Characterization of T-helper epitopes of the glycoprotein of vesicular stomatitis virus

scientific article published on March 1994

Characterization of an Lyt-2+ alloreactive cytotoxic T cell clone specific for H-2Db that cross-reacts with I-Ek

scientific article published on 01 November 1986

Characterization of virus-specific cytotoxic T cell clones from allogeneic bone marrow chimeras

scientific article published in February 1987

Class II major histocompatibility complex-restricted T cell function in CD4-deficient mice

scientific article

Clearance of lymphocytic choriomeningitis virus in antibody- and B-cell-deprived mice

scientific article published on May 1988

Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny

scientific article published on May 1992

Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa

scientific article

Cloned cytotoxic T cells specific for lymphocytic choriomeningitis virus induce acute disease and primary footpad swelling in infected mice

scientific article

Combinatorial immunoglobulin light chain variability creates sufficient B cell diversity to mount protective antibody responses against pathogen infections

scientific article published in April 2003

Comparison of T cell-mediated immune responsiveness of NZB, (NZB x &NZW)F1 hybrid and other murine strains ⬇️

scientific article published on July 1, 1977

Comparison of activation versus induction of unresponsiveness of virus-specific CD4+ and CD8+ T cells upon acute versus persistent viral infection

scientific article

Comparison of the sensitivity of in vivo and in vitro assays for detection of antiviral cytotoxic T cell activity

scientific article published in October 1993

Complement facilitates early prion pathogenesis

scientific article published in April 2001

Contra: CD8+ T-cell-mediated suppression without 'suppressor' T cells?

scientific article published on 01 January 1993

Control of early viral and bacterial distribution and disease by natural antibodies

scientific article published on 01 December 1999

Correlates of protective viruses damaging to HIV infection

scientific article published on 01 May 1996

Correlation of T cell independence of antibody responses with antigen dose reaching secondary lymphoid organs: implications for splenectomized patients and vaccine design

scientific article published on 01 June 2000

Correlation of anti-viral B cell responses and splenic morphology with expression of B cell-specific molecules

scientific article published on 01 September 2000

Correlation of tolerogenicity of a viral antigen with its immunogenicity

scientific article published on 01 June 1997

Cortisone-resistant effector T cells in acute lymphocytic choriomeningitis and Listeria monocytogenes infection of mice.

scientific article

Cross-reactive cytotoxic T cells to serologically distinct vesicular stomatitis virus ⬇️

scientific article published on May 1, 1980

Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis

scientific article

Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infection ⬇️

scientific article published on October 1, 1997

Crystal-ball gazing--the future of immunological research viewed from the cutting edge

scientific article published on January 2007

Cytotoxic T Cells Are Sensitised to ‘Altered Self’ in Lymphocytic Choriomeningitis Virus Infections

Cytotoxic T cell activity is strain-specific in outbred mice infected with lymphocytic choriomeningitis virus ⬇️

scientific article published on December 1, 1975

Cytotoxic T cell clone-specific monoclonal antibodies used to select clonotypic antigen-specific cytotoxic T cells

scientific article published on January 1985

Cytotoxic T cell lysis of target cells fused with liposomes containing influenza virus haemagglutinin and neuraminidase

scientific article published on June 1985

Cytotoxic T cell response to lymphocytic choriomeningitis virus. Properties of precursors of effector T cells, primary effector T cells and memory T cells in vitro and in vivo ⬇️

scientific article published on September 1, 1977

Cytotoxic T cells learn specificity for self H–2 during differentiation in the thymus ⬇️

scientific article published on January 19, 1978

Cytotoxic cells induced during lymphocytic choriomeningitis virus infection of mice. II. "Specificities" of the natural killer cells ⬇️

scientific article published on February 1, 1979

Cytotoxic thymus-derived lymphocytes in cerebrospinal fluid of mice with lymphocytic choriomeningitis ⬇️

scientific article published on November 1, 1973

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

scientific journal article

Decreased tumor surveillance in perforin-deficient mice

scientific article

Delayed type hypersensitivity (DTH) in anti-IgM-treated B cell-depleted mice: analysis of induction and effector phase

scientific article published on 01 September 1988

Deletion of self-reactive T cells before entry into the thymus medulla

scientific article published in Nature

Deliberate removal of T cell help improves virus-neutralizing antibody production.

scientific article published on 8 August 2004

Dendritic cells efficiently induce protective antiviral immunity

scientific article

Dendritic cells in autoimmune diseases ⬇️

scientific article published on December 1, 2001

Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue

scientific article

Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus

scientific article

Development of follicular dendritic cells in lymph nodes of B-cell-depleted mice

scientific article published on 01 November 1988

Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity

scientific article

Different susceptibility of cytotoxic T cells to CD95 (Fas/Apo-1) ligand-mediated cell death after activation in vitro versus in vivo.

scientific article

Differentiation of T cells: thymic selection of specificity for self

scientific article published on 01 January 1982

Direct quantitation of rapid elimination of viral antigen-positive lymphocytes by antiviral CD8(+) T cells in vivo

scientific article published in May 2000

Discrepancy between in vitro measurable and in vivo virus neutralizing cytotoxic T cell reactivities. Low T cell receptor specificity and avidity sufficient for in vitro proliferation or cytotoxicity to peptide-coated target cells but not for in viv ⬇️

scientific article published on August 1, 1992

Distinct fates of self-specific T cells developing in irradiation bone marrow chimeras: clonal deletion, clonal anergy, or in vitro responsiveness to self-Mls-1a controlled by hemopoietic cells in the thymus

scientific article

Distinct patterns of virus-specific T cell-mediated cytolysis of transformed versus primary target cells

scientific article

Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities

scientific article published in August 1990

Do thymically and strictly extrathymically developing T cells generate similar immune responses?

scientific article

Donor cell persistence and activation-induced unresponsiveness of peripheral CD8+ T cells

scientific article published in March 2000

Early antibodies specific for the neutralizing epitope on the receptor binding subunit of the lymphocytic choriomeningitis virus glycoprotein fail to neutralize the virus

scientific article

Early appearance of sensitized lymphocytes in mice infected with Listeria monocytogenes

scientific article published on 01 February 1974

Early high-affinity neutralizing anti-viral IgG responses without further overall improvements of affinity

scientific article

Early type I interferon-mediated signals on B cells specifically enhance antiviral humoral responses

scientific article published on 01 August 2006

Effect of cell dose and dose of infectious agent on expression of protection against Listeria monocytogenes and Ectromelia virus in cell transfer models ⬇️

scientific article published on June 1, 1975

Effect of cyclosporin A on immunity to Listeria monocytogenes

scientific article published on April 1986

Effect of rabbit anti-asialo GM1 treatment in vivo or with anti-asialo GM1 plus complement in vitro on cytotoxic T cell activities.

scientific article published in June 1986

Effector T-cell induction and T-cell memory versus peripheral deletion of T cells

scientific article

Effects of cyclosporin A on humoral immune response and resistance against vesicular stomatitis virus in mice.

scientific article published on March 1986

Effects of promyelocytic leukemia protein on virus-host balance

scientific article

Effects of treatment with IL-2 receptor specific monoclonal antibody in mice

scientific article published on 01 April 1990

Effects of treatment with IL-2 receptor specific monoclonal antibody in mice. Inhibition of cytotoxic T cell responses but not of T help

article

Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHC

scientific article

Efficient immune responses in mice lacking N-region diversity

article

Endogenous neosynthesis vs. cross-presentation of viral antigens for cytotoxic T cell priming

scientific article published on 31 October 2003

Enhanced Virus Clearance by Early Inducible Lymphocytic Choriomeningitis Virus-Neutralizing Antibodies in Immunoglobulin-Transgenic Mice ⬇️

scientific article published on March 1, 1998

Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice.

scientific article published on July 1994

Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex

scientific article published in July 1975

Enhanced positive selection of a transgenic TCR by a restriction element that does not permit negative selection.

scientific article published on February 1993

Enhanced tumor susceptibility of immunocompetent mice infected with lymphocytic choriomeningitis virus

scientific article published on January 1990

Enhanced virus replication and inhibition of lymphocytic choriomeningitis virus disease in anti-gamma interferon-treated mice

scientific article published on June 1989

Enhancement of disease by neutralizing antiviral antibodies in the absence of primed antiviral cytotoxic T cells

scientific article published on 01 December 1993

Erratum: Corrigendum: Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

scholarly article published in Nature Medicine

Erratum: Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

scientific article published in September 2001

Erratum: Specific cytotoxic T cells eliminate cells producing neutralizing antibodies

scientific article published in Nature

Erratum: Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

scientific article published in Nature

Escape of thymocytes and mature T cells from clonal deletion due to limiting tolerogen expression levels

scientific article published on 01 October 1994

Evidence for a differential avidity model of T cell selection in the thymus

scientific article published in February 1994

Evidence for a role of IFN γ in control ofListeria monocytogenes in T cell deficient mice ⬇️

scientific article published on June 15, 1991

Exacerbation of experimental murine cutaneous leishmaniasis with CD4+Leishmania major-specific T cell lines or clones which secrete interferon-γ and mediate parasite-specific delayed-type hypersensitivity ⬇️

scientific article published on March 1, 1991

Exhaustion of cytotoxic T cells during adoptive immunotherapy of virus carrier mice can be prevented by B cells or CD4+ T cells

scientific article published in February 2002

Experiments and speculation on antiviral specificity of T and B cells

scientific article

Expression of T cell receptor gamma-chain in murine cytotoxic T cells: analysis of a highly transcribed nonrearranged gene cluster

scientific article

Expression of lymphotoxin beta governs immunity at two distinct levels

scientific article published in August 2006

Extralymphatic virus sanctuaries as a consequence of potent T-cell activation

scientific article published on 4 November 2007

Extrathymic positive selection of alpha beta T-cell precursors in nude mice

scientific article published on January 9, 1992

FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory

scientific article published in June 2000

Fate of potentially self-reactive T cells in neonatal mice: analysis of V beta 6+ T cells in Mlsa mice

scientific article published on 01 January 1989

Felix Hoppe-Seyler Lecture 1997. Protective antibody responses against viruses

scientific article published on August 1, 1997

Fewer protective cytotoxic T-cell epitopes than T-helper-cell epitopes on vesicular stomatitis virus ⬇️

scientific article published on June 1, 1993

Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8

scientific article

Formalin inactivation of vesicular stomatitis virus impairs T-cell- but not T-help-independent B-cell responses

scientific article published on July 1993

Free recirculation of memory B cells versus antigen-dependent differentiation to antibody-forming cells.

scientific article published in October 1994

Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC.

scholarly article

Functional analysis of T lymphocyte subsets in antiviral host defense.

scientific article published in April 1987

Functional in vivo MHC class II loading by endogenously synthesized glycoprotein during viral infection

scientific article published in June 1997

Functional role of type I and type II interferons in antiviral defense

scientific article

Games that viruses play ⬇️

scientific article published on December 12, 1991

Gene technology and democracy

scientific article published in November 1997

General and specific immunosuppression caused by antiviral T-cell responses

scientific article

General immunologic fundamentals and an example of virally induced immunosuppression

scientific article published on 01 January 1991

Generation of agammaglobulinaemic mice by prenatal and postnatal exposure to polyclonal or monoclonal anti-IgM antibodies

scientific article published on 01 October 1986

Generation of virus-specific cytolytic activity in human peripheral lymphocytes after vaccination with vaccinia virus and measles virus

scientific article published on November 17, 1978

Genes required for cytotoxicity against virus-infected target cells in K and D regions of H-2 complex

scientific article

Graft-versus-host reactions in F1 hybrid mice: MHC-restriction-independent generalized depression of virus-specific cytotoxic T cell response

scientific article published in May 1984

H-2 compatability requirement for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus. Different cytotoxic T-cell specificities are associated with structures coded for in H-2K or H-2D; ⬇️

scientific article published on June 1, 1975

H-2 compatibility is required for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus ⬇️

scientific article published on February 1, 1975

H-2 compatibility requirement for virus-specific T cell-mediated effector functions in vivo. I. Specificity of T cells conferring antiviral protection against lymphocytic choriomeningitis virus is associated with H-2K and H-2D ⬇️

scientific article published on November 1, 1976

H-2 compatibility requirement for virus-specific T-cell-mediated cytolysis. Evaluation of the role of H-2I region and non-H-2 genes in regulating immune response

scientific article

H-2 compatibility requirement for virus-specific T-cell-mediated cytolysis. The H-2K structure involved is coded by a single cistron defined by H-2Kb mutant mice ⬇️

scientific article published on February 1, 1976

H-2 restriction of cell-mediated immunity to an intracellular bacterium: effector T cells are specific for Listeria antigen in association with H-21 region-coded self-markers ⬇️

scientific article published on May 1, 1977

H-2 restriction of virus-specific T-cell-mediated effector functions in vivo. II. Adoptive transfer of delayed-type hypersensitivity to murine lymphocytic choriomeningits virus is restriced by the K and D region of H-2 ⬇️

scientific article published on September 1, 1976

H-2 restriction of virus-specific cytotoxicity across the H-2 barrier. Separate effector T-cell specificities are associated with self-H-2 and with the tolerated allogeneic H-2 in chimeras

scientific article

HLA and H-2

journal article; published in Nature on 1979-8

Heterospecific cytotoxic cell activity induced during the first three days of acute lymphocytic choriomeningitis virus infection in mice ⬇️

scientific article published on August 18, 1977

Hierarchies of antigen-specific cytotoxic T-cell responses

scientific article published on 01 August 1998

Histological analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells

scientific article published in September 2005

Host-determined T cell fine specificity for self-H-2 in radiation bone-marrow chimeras of standard C57BL/6 (H-2b) mutantHz1 (H-2ba), and F1 mice ⬇️

scientific article published on December 1, 1978

How can we stimulate the immune system in vivo?

scientific article published on 01 January 1992

How many specific B cells are needed to protect against a virus?

scientific article published in May 1994

How to escape immune surveillance?

scientific article published on 01 January 1982

Hypercholesterolemia exacerbates virus-induced immunopathologic liver disease via suppression of antiviral cytotoxic T cell responses

scientific article

Hypergammaglobulinemia and autoantibody induction mechanisms in viral infections

scientific article published on 10 March 2003

IL-12 is not required for induction of type 1 cytokine responses in viral infections

scientific article published on 01 January 1999

IL-4 and IL-10 antagonize IL-12-mediated protection against acute vaccinia virus infection with a limited role of IFN-gamma and nitric oxide synthetase 2.

scientific article published in January 2000

Identical V beta T-cell receptor genes used in alloreactive cytotoxic and antigen plus I-A specific helper T cells

scientific article published on 01 May 1985

Identification and characterization of a novel antigen from the nematode Nippostrongylus brasiliensis recognized by specific IgE.

scientific article

Identification of an N-terminal trimeric coiled-coil core within arenavirus glycoprotein 2 permits assignment to class I viral fusion proteins

scientific article

IgA production without mu or delta chain expression in developing B cells

scientific article published in July 2001

IgD can largely substitute for loss of IgM function in B cells ⬇️

scientific article published on June 25, 1998

Immune defence in mice lacking type I and/or type II interferon receptors

scientific article published on December 1995

Immune protection vs. immunopathology vs. autoimmunity: a question of balance and of knowledge

scientific article published on April 1993

Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression ⬇️

scientific article published on December 1, 1991

Immune response against vaccinia virus in rhesus monkeys: no evidence for primary MHC-restricted cytolytic T cells.

scientific article published in January 1984

Immune response in humans after vaccination with vaccinia virus: generation of a virus-specific cytotoxic activity by human peripheral lymphocytes ⬇️

scientific article published on October 1, 1977

Immune response in mice that lack the interferon-gamma receptor

scientific article published on 19 March 1993

Immune responses in interleukin-2-deficient mice

scientific article published in Science

Immune responses in the absence of costimulation: viruses know the trick

scientific article published in December 1998

Immune surveillance against a solid tumor fails because of immunological ignorance

scientific article published on March 1999

Immune surveillance and AIDS progression ⬇️

scientific article published on 01 July 1997

Immunity 2000.

scientific article published in September 2000

Immunity against solid tumors?

scientific article

Immunity to infection

scientific article published on 01 August 1996

Immunity to lymphocytic choriomeningitis virus in B cell-depleted mice: evidence for B cell and antibody-independent protection by memory T cells

scientific article published in August 1986

Immunity to viruses in B cell-deficient mice: influence of antibodies on virus persistence and on T cell memory

scientific article published in September 1996

Immunity, immunopathology and vaccines against HIV?

scientific article

Immunization with recombinant protein: conditions for cytotoxic T cell and/or antibody induction ⬇️

scientific article published on 01 December 1994

Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus

scientific article published in April 1995

Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene

scientific article

Immunodeficiency of alymphoplasia mice (aly/aly) in vivo: structural defect of secondary lymphoid organs and functional B cell defect

scientific article

Immunodominant T cell epitope from signal sequence

scientific article published on August 21, 1992

Immunogenicity of a viral model vaccine after different inactivation procedures

scientific article published on 01 May 1994

Immunologic cellular effector mechanisms as examples of cellular interactions

scientific article published on January 1, 1978

Immunological memory ≠ protective immunity ⬇️

scientific article published on 06 April 2012

Immunological memory: lessons from the past and a look to the future

scientific article published in February 2016

Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytes choriomeningitis ⬇️

scientific article published on October 11, 1974

Immunological tolerance to a non-cytopathic virus is not inheritable in mice ⬇️

scientific article published on June 1, 1984

Immunology and immunity studied with viruses

scientific article published on January 1997

Immunology taught by viruses

scientific article published on January 1996

Immunopathology or organ-specific autoimmunity as a consequence of virus infection

scientific article published on August 1996

Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling

scientific article

Immunoreactivity of long lived H-2 incompatible irradiation chimeras (H-2d leads to H-2b) ⬇️

scientific article published on 01 June 1982

Immunosuppression by a noncytolytic virus via T cell mediated immunopathology. Implication for AIDS.

scientific article

Immunosuppression by embryonic liver cells ⬇️

scientific article published on December 1, 1975

Immunosuppression by lymphocytic choriomeningitis virus infection: competent effector T and B cells but impaired antigen presentation

scientific article published in July 1992

Immunosuppression in mice by lymphocytic choriomeningitis virus infection: time dependence during primary and absence of effects on secondary antibody responses

scientific article published in October 1990

Immunotherapy with dendritic cells directed against tumor antigens shared with normal host cells results in severe autoimmune disease

scientific article

Impaired generation of anti-viral cytotoxicity against lymphocytic choriomeningitis and vaccinia virus in mice treated with CD4-specific monoclonal antibody

scientific article published in December 1989

Impaired immune and acute-phase responses in interleukin-6-deficient mice

scientific article published in March 1994

Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells ⬇️

scientific article published on November 15, 1993

Impairment of CD4(+) T cell responses during chronic virus infection prevents neutralizing antibody responses against virus escape mutants

scientific article

In irradiation chimeras, K or D regions of the chimeric host, not of the donor lymphocytes, determine immune responsiveness of antiviral cytotoxic T cells ⬇️

scientific article published on September 1, 1978

In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytes

scientific article published on December 1991

In vivo antigen loading and activation of dendritic cells via a liposomal peptide vaccine mediates protective antiviral and anti-tumour immunity

scientific article published on 01 August 2000

In vivo selection of neutralization-resistant virus variants but no evidence of B cell tolerance in lymphocytic choriomeningitis virus carrier mice expressing a transgenic virus-neutralizing antibody

scientific article published in April 1999

Inability of mice to generate cytotoxic T lymphocytes to vesicular stomatitis virus restricted to H-2Kk or H-2Dk ⬇️

scientific article published on February 1, 1981

Increased bactericidal macrophage activity induced by immunological stimuli is dependent on interferon (IFN)-gamma. Interference of anti-IFN-gamma but not anti-IFN-alpha/beta with modulation of macrophage activity caused by lymphocytic choriomeningi

scientific article published in August 1988

Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses

scholarly article

Induced prion protein controls immune-activated retroviruses in the mouse spleen

scientific article

Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.

scientific article

Induction of IgE and allergic-type responses in fur mite-infested mice.

scientific article

Induction of Protective Cytotoxic T Cell Responses in the Presence of High Titers of Virus-neutralizing Antibodies: Implications for Passive and Active Immunization ⬇️

scientific article published on February 16, 1998

Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha

scientific article published in June 1993

Induction of long-lived germinal centers associated with persisting antigen after viral infection

scientific article

Induction of optimal anti-viral neutralizing B cell responses by dendritic cells requires transport and release of virus particles in secondary lymphoid organs

scientific article published in January 2000

Induction of protective cytotoxic T cells with viral proteins

scientific article published on September 1994

Induction or prevention of immunopathological disease by cloned cytotoxic T cell lines specific for lymphocytic choriomeningitis virus

scientific article

Inflammatory process in murine lymphocytic choriomeningitis is maximal in H-2K or H-2D compatible interactions

scientific article

Influence of one virus infection on a second concurrent primary in vivo antiviral cytotoxic T-cell response ⬇️

scientific article published on August 1, 1983

Inhibition of HSV-1 and vaccinia virus replication by cephalosporin derivatives

scientific article

Inhibition of hapten-specific cytotoxic T cell recognition by monoclonal anti-hapten antibodies

scientific article published on 01 March 1985

Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections

scholarly article

Interferon gamma-producing gammadelta T cell-dependent antibody isotype switching in the absence of germinal center formation during virus infection.

scientific article published on February 1998

Intralymphatic immunization enhances DNA vaccination.

scholarly article

Intrathymic elimination of Mlsa-reactive (V beta 6+) cells during neonatal tolerance induction to Mlsa-encoded antigens

scientific article

Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation

scientific article published on 01 March 2005

Ir-genes in H-2 regulate generation of anti-viral cytotoxic T cells. Mapping to K or D and dominance of unresponsiveness ⬇️

scientific article published on August 1, 1978

Kinetics of clonal deletion varies with tolerizing antigen

scientific article published on 01 August 1992

Kinetics of protective antibodies are determined by the viral surface antigen

scientific article published on October 2004

Lack of correlation between serum titres of interferon alpha, beta, natural killer cell activity and clinical susceptibility in mice infected with two isolates of lymphocytic choriomeningitis virus

scientific article

Lactate dehydrogenase-elevating virus (LDV): lifelong coexistence of virus and LDV-specific immunity ⬇️

scientific article published on August 15, 1997

Leflunomide-mediated suppression of antiviral antibody and Tcell responses: differential restoration by uridine

scientific article

Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model

scientific article published in November 2000

Living donor liver transplantation and tolerance: a potential strategy in cholangiocarcinoma

scientific article published on 01 September 2003

Localization dose and time of antigens determine immune reactivity

scientific article

Localization of T helper cell epitopes in the vesicular stomatitis virus: the nucleoprotein is responsible for serotype cross-reactive T help.

scientific article published on January 1994

Long-lasting immunity by early infection of maternal-antibody-protected infants

scientific article published in January 2010

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors.

scientific article

Long-term maternal imprinting of the specific B cell repertoire by maternal antibodies

scientific article published on 01 January 2008

Low responsiveness to Dk or Db plus vaccinia virus or to Kk plus lymphocytic choriomeningitis virus assessed by availability of D or K products.

scientific article

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function ⬇️

scientific article published on June 6, 1991

Lymphocyte-mediated cytotoxicity in vitro and in vivo: mechanisms and significance

scientific article published on August 1995

Lymphocytic choriomeningitis virus and immunology

scientific article

Lymphohemopoietic origin of the immunogenic, virus-antigen-presenting cells triggering anti-viral T-cell responses

scientific article published in March 1980

Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

scientific article published on 25 January 2004

Lysis of infected cells in vivo by antiviral cytolytic T cells demonstrated by release of cell internal viral proteins

scientific article published on 01 July 1993

MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice

scientific article published in May 1994

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

scientific article published on January 1, 1979

Macrophage activation in mice lacking thymus-derived (T) cells

scientific article published on May 15, 1975

Maintenance of memory CTL responses by T helper cells and CD40-CD40 ligand: antibodies provide the key.

scientific article published in February 2004

Major Transplantation Antigens in Host Responses to Infection ⬇️

scientific article published on July 1, 1978

Major histocompatibility complex binding and T cell recognition of a viral nonapeptide containing a minimal tetrapeptide ⬇️

scientific article published on May 1, 1991

Major histocompatibility complex--dependent T cell epitopes of lymphocytic choriomeningitis virus nucleoprotein and their protective capacity against viral disease

scientific article published in September 1989

Major histocompatibility complex-linked susceptibility or resistance to disease caused by a noncytopathic virus varies with the disease parameter evaluated

scientific article

Major histocompatibility gene complex-disease associations may reflect T cell-mediated immunopathology

scientific article published on April 1986

Major transplantation antigens in T cell-mediated immunity: a comparison of the transplantation reaction with antiviral immunity

scientific article published on August 1, 1978

Major transplantation antigens, viruses, and specificity of surveillance T cells

scientific article

Mapping of the dominant neutralizing antigenic site of a virus using infected cells

scientific article published in February 1996

Marginal zone macrophages and immune responses against viruses

scientific article published on 01 August 2002

Maternal antibodies, childhood infections, and autoimmune diseases

scientific article

Mechanisms of neonatal mucosal antibody protection.

scientific article

Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

scientific journal article

Microchimerism maintains deletion of the donor cell-specific CD8+ T cell repertoire

scientific article

Models for recognition of virally modified cells by immune thymus-derived lymphocytes

article

Molecular analysis of the antigen receptor of virus-specific cytotoxic T cells and identification of a new V alpha family

scientific article

Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo

scientific article published on January 1996

Monoclonal antibodies against viral determinants are not restricted to the K/D end of the major histocompatibility complex

scientific article

Monovalent single-chain Fv fragments and bivalent miniantibodies bound to vesicular stomatitis virus protect against lethal infection.

scientific article published in December 1996

Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice

scientific article

Murine antiviral proliferative and cytotoxic T-cell responses: specificities and role of the H-21 region

scientific article

MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus

scientific article published on September 2007

Natural IgE production in the absence of MHC Class II cognate help

scientific article published on 01 March 2006

Natural antibodies and complement link innate and acquired immunity

scientific article

Natural cytotoxic cells in NZB mice: Spontaneous in vivo and in vitro primed activity and structural characteristics ⬇️

scientific article published on April 1, 1979

Natural killer cells vs cytotoxic T cells in the peripheral blood of virus-infected mice.

scientific article

Neonatal tolerance to MIs-1a determinants: deletion or anergy of V beta 6+ T lymphocytes depending upon MHC compatibility of neonatally injected cells

scientific article published on 01 February 1991

Neonatally tolerant mice fail to react against virus-infected tolerated cells ⬇️

scientific article published on April 28, 1977

Neutralizing antiviral B cell responses

scientific article published on January 1997

Neutralizing antiviral antibodies reduce hematogenic viral spread but not antiviral cytotoxic T cell induction and subsequent immunopathology

scientific article published on 01 May 2001

Neutralizing antiviral antibody responses ⬇️

scientific article published on January 1, 2001

No functional gamma-chain transcripts detected in an alloreactive cytotoxic T-cell clone

scientific article published on June 1986

Non-tolerant B cells cause autoimmunity in anti-CD8 IgG2a-transgenic mice

scientific article

Nonimmunogenic tumor cells may efficiently restimulate tumor antigen-specific cytotoxic T cells.

scientific article published on May 1993

Nonneutralizing antibodies binding to the surface glycoprotein of lymphocytic choriomeningitis virus reduce early virus spread.

scientific article

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

scientific journal article

Novartis Prizes for Immunology 2001, Stockholm

scientific article published in March 2002

Nuclear myxovirus-resistance protein Mx is a minor histocompatibility antigen

scientific article published on March 1990

Of mice and men: cytotoxic T cells and AIDS pathogenesis

scientific article published on October 1, 1999

On 'reactivity' versus 'tolerance'.

scientific article published in August 2004

On T cell memory: arguments for antigen dependence

scientific article published on April 1996

On cross-priming of MHC class I-specific CTL: rule or exception?

scientific article

On differences between immunity and immunological memory

scientific article

On immunity against infections and vaccines: credo 2004.

scientific article published in July 2004

On immunological memory

scientific article

On immunological memory

scientific article published on 01 January 1996

On natural and artificial vaccinations

scientific article

On observing and analyzing disease versus signals

scientific article published in January 2007

On plasma cell longevity or brevity

scientific article published on 7 June 2014

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases

scientific article published on 01 April 1989

On the immunocompetence of H-2 incompatible irradiation bone marrow chimeras

scientific article published on 01 May 1980

On the key role of secondary lymphoid organs in antiviral immune responses studied in alymphoplastic (aly/aly) and spleenless (Hox11(-)/-) mutant mice.

scientific article

On the pathogenesis of perforin defects and related immunodeficiencies

scientific article published on 01 November 2000

On the role of antigen in maintaining cytotoxic T-cell memory

scientific article published on September 1996

On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells

scientific article

On the role of viruses in the evolution of immune responses

scientific article

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition? ⬇️

scientific article published on March 1, 1978

Ontogeny and selection of the T cell repertoire in transgenic mice.

scientific article

Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes

scientific article published in Nature

Parameters governing exhaustion of rare T cell-independent neutralizing IgM-producing B cells after LCMV infection

scientific article published on 01 December 2006

Passive oral immunization with bovine immunoglobulins: enterpathogenic Escherichia coli from infants and bovine anti-E. coli lactoserum assayed in the rabbit ileal loop model

scientific article published on December 1975

Peptide antigen treatment of naive and virus-immune mice: antigen-specific tolerance versus immunopathology

scientific article published on May 1997

Peptide-induced T cell receptor down-regulation on naive T cells predicts agonist/partial agonist properties and strictly correlates with T cell activation

scientific article published on 01 September 1997

Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model

scientific article

Peptide-induced antiviral protection by cytotoxic T cells

scientific article published on February 1991

Peptides control the gain and loss of allele specificity by mutated MHC class I molecules

scientific article published on 01 May 1995

Perforin dependence of natural killer cell-mediated tumor control in vivo

scientific article published in December 1995

Perforin-independent regulation of dendritic cell homeostasis by CD8(+) T cells in vivo: implications for adaptive immunotherapy

scientific article

Peripheral T cells in mice lacking p56lck do not express significant antiviral effector functions

scientific article published on 01 July 1993

Peripheral clonal deletion of antiviral memory CD8+ T cells

scientific article published in December 1993

Peritoneal macrophages as target cells for measuring virus-specific T cell mediated cytotoxicity in vitro

scientific article published on September 1975

Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice.

scientific article published on October 1999

Persistence of vesicular stomatitis virus in cloned interleukin-2-dependent natural killer cell lines

scientific article published in November 1986

Phenotypic analysis of TNFR1-deficient mice and characterization of TNFR1-deficient fibroblasts in vitro.

scientific article

Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection.

scientific article published in October 2008

Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus

scientific article

Positive and negative selection of the T-cell antigen receptor repertoire in nontransgenic mice

scientific article

Positive selection of CD4+ thymocytes controlled by MHC class II gene products

scientific article published in Nature

Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity

scientific article

PrP expression in B lymphocytes is not required for prion neuroinvasion

article published in 1998

Preferential positive selection of V alpha 2+ CD8+ T cells in mouse strains expressing both H-2k and T cell receptor V alpha a haplotypes: determination with a V alpha 2-specific monoclonal antibody

scientific article published in February 1992

Presentation of endogenous viral proteins in association with major histocompatibility complex class II: on the role of intracellular compartmentalization, invariant chain and the TAP transporter system

scientific article published on December 1995

Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies

scientific article published on 6 September 2001

Primary antibody responses to a well-defined and unique hapten are not enhanced by preimmunization with carrier: analysis in a viral model

scientific article published on April 1986

Proceedings: Immunosuppression by embryonic liver cells: a model for establishment of tolerance to self

scientific article published on 01 December 1975

Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients

scientific article

Production of random classes of immunoglobulins in brain tissue during persistent viral infection paralleled by secretion of interleukin-6 (IL-6) but not IL-4, IL-5, and gamma interferon

scientific article published on March 1991

Promethean viruses?

scientific article published in Nature

Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"?

scientific article

Protection and damage by antiviral immunity.

scientific article published on January 1993

Protection and damage by immunity to intracellular parasites

scientific article published on April 1, 1983

Protective 'immunity' by pre-existent neutralizing antibody titers and preactivated T cells but not by so-called 'immunological memory'.

scientific article published on June 2006

Protective Immunity Does Not Correlate with the Hierarchy of Virus-specific Cytotoxic T Cell Responses to Naturally Processed Peptides ⬇️

scientific article published on May 18, 1998

Protective T cell-independent antiviral antibody responses are dependent on complement

scientific article

Protective antiviral cytotoxic T cell memory is most efficiently maintained by restimulation via dendritic cells.

scientific article published on August 1999

Protective long-term antibody memory by antigen-driven and T help-dependent differentiation of long-lived memory B cells to short-lived plasma cells independent of secondary lymphoid organs

scientific article

Public versus personal serotypes of a viral quasispecies.

scientific article

Qualitative and quantitative requirements for CD4+ T cell-mediated antiviral protection

scientific article published on 01 March 1999

Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates

scientific article published on June 1991

Quantitative studies of the growth and rejection of allogeneic tumour cells in mouse cerebrospinal fluid. Elimination in the absence of H-2 differences ⬇️

scientific article published on February 1, 1975

Rapid Peptide Turnover and Inefficient Presentation of Exogenous Antigen Critically Limit the Activation of Self-Reactive CTL by Dendritic Cells

scientific article published on 01 March 2001

Reactive oxygen species delay control of lymphocytic choriomeningitis virus ⬇️

scientific article published on January 18, 2013

Reactivity and tolerance of virus-specific T cells

scientific article published on January 1989

Recombinant vaccines

scientific article published on 01 June 1991

Recombination of retrotransposon and exogenous RNA virus results in nonretroviral cDNA integration

scientific article

Reduced Incidence and Delayed Onset of Diabetes in Perforin-deficient Nonobese Diabetic Mice ⬇️

scientific article published on October 6, 1997

Regulation of IgG antibody titers by the amount persisting of immune-complexed antigen

scientific article published on 01 October 1994

Regulation of the immune response by antigen

scientific article

Rejection of allogeneic tumor cells growing in mouse cerebrospinal fluid Functional analysis of the inflammatory process

scientific article published on 01 March 1981

Requirement for neutralizing antibodies to control bone marrow transplantation-associated persistent viral infection and to reduce immunopathology

scientific article published on 01 October 2005

Resistance of lymphocytic choriomeningitis virus to alpha/beta interferon and to gamma interferon

scientific article published on March 1994

Response: immunology taught by darwin

scientific article

Responses to Cohn's discussion on the Zinkernagel-Hengartner 'Credo 2004'

scientific article published on 01 September 2005

Restriction by H-2 gene complex of transfer of cell-mediated immunity to Listeria monocytogenes

scientific article published in Nature

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.

scientific article

Restriction specificities, alloreactivity, and allotolerance expressed by T cells from nude mice reconstituted with H-2-compatible or -incompatible thymus grafts

scientific article published on February 1980

Restriction specificity of virus-specific cytotoxic T cells from thymectomised irradiated bone marrow chimeras reconstituted with thymus grafts

scientific article published on April 1, 1981

Review: Cellular immune responses to intracellular parasites: role of the major histocompatibility gene complex and thymus in determining immune responsiveness and susceptibility to disease ⬇️

scientific article published on January 1, 1979

Role of T helper cell precursor frequency on vesicular stomatitis virus neutralizing antibody responses in a T cell receptor beta chain transgenic mouse

scientific article

Role of TCR-restricting MHC density and thymic environment on selection and survival of cells expressing low-affinity T cell receptors

scientific article published in April 2004

Role of an intact splenic microarchitecture in early lymphocytic choriomeningitis virus production.

scientific article

Role of dendritic cells in the induction and maintenance of autoimmune diseases

scientific article

Role of repetitive antigen patterns for induction of antibodies against antibodies

scientific article

Role of the H-2 gene complex in cell-mediated immunity to infectious disease

scientific article published on December 1977

Role of the H-2I region in the generation of an antiviral cytotoxic T-cell response in vitro

scientific article published on 01 August 1980

Role of tumor necrosis factor in Listeria resistance of nude mice

scientific article published in January 1990

Role of virus and host variables in virus persistence or immunopathological disease caused by a non-cytolytic virus

scientific article

Role of virus-induced cell-mediated immune reactions

scientific article published on 01 January 1981

Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

scientific article published in Nature

Science and sensibility: an interview with Professor Rolf M. Zinkernagel, Nobel Prize Winner for Medicine 1996. Interview by Hrishikesh Satish Kulkarni and Ajit H. Goenka.

scientific article published on 6 November 2007

Scrapie pathogenesis in subclinically infected B-cell-deficient mice

scientific article

Search for suppression of T cells specific for the second nonhost H-2 haplotype in F1 leads to P irradiation bone marrow chimeras ⬇️

scientific article published on May 1, 1979

Secondary cytotoxic cell response to lymphocytic choriomeningitis virus II. Nature and specificity of effector cells ⬇️

scientific article published on August 1, 1976

Secondary rearrangements and hypermutation generate sufficient B cell diversity to mount protective antiviral immunoglobulin responses

scientific article

Selection of restriction specificities of virus-specific cytotoxic T cells in the thymus: no evidence for a crucial role of antigen-presenting cells ⬇️

scientific article published on December 1, 1982

Selective and unidirectional membrane redistribution of an H-2 antigen with an antibody-clustered viral antigen: relationship to mechanisms of cytotoxic T-cell interactions ⬇️

scientific article published on September 1, 1979

Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy ⬇️

scientific article published on August 29, 1997

Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgene

scientific article

Skin test to assess virus-specific cytotoxic T-cell activity ⬇️

scientific article published on August 15, 1992

Some general aspects of immunity to viruses

scientific article published on December 1994

Specific cytotoxic T cells eliminate B cells producing virus-neutralizing antibodies [corrected]

scientific article published in August 1996

Specific immune lysis of paramyxovirus-infected cells by H-2-compatible thymus-derived lymphocytes ⬇️

scientific article published on July 1, 1976

Specificity and development of cytotoxic thymus-derived lymphocytes in lymphocytic choriomeningitis

scientific article published on April 1, 1974

Specificity of Virus-Immune Effector T Cells for H-2K or H-2D Compatible Interactions: Implications for H-Antigen Diversity ⬇️

scientific article published on January 1, 1976

Specificity of in vitro cytotoxic T cell clones directed against vesicular stomatitis virus.

scientific article published in July 1983

Speculations on the Role of Major Transplantation Antigens in Cell-Mediated Immunity Against Intracellular Parasites ⬇️

scientific article published on January 1, 1978

Strictly transporter of antigen presentation (TAP)-dependent presentation of an immunodominant cytotoxic T lymphocyte epitope in the signal sequence of a virus protein ⬇️

scientific article published on November 1, 1995

Studies on immunity to lymphocytic choriomeningitis virus

scientific article

Suppression by cyclosporin A of murine T-cell-mediated immunity against viruses in vivo and in vitro

scientific article published in February 1985

Suppression of B cell development and antibody responses in mice with polyclonal rabbit and monoclonal rat anti-IgM antibodies. I. Characterization of the suppressed state

scientific article published on 01 January 1985

Suppression of the generation of secondary virus-specific proliferative and cytotoxic T lymphocytes by suppressor cells induced during primary anti-viral sensitization in vitro.

scientific article published in May 1981

Suppression of virus-specific antibody production by CD8+ class I-restricted antiviral cytotoxic T cells in vivo ⬇️

scientific article published on June 1, 1992

Suppressive effects of B-lactam-antibiotics on in vitro generation of cytotoxic T-cells

scientific article published on 01 January 1986

Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D

scientific article

Susceptibility to murine lymphocytic choriomeningitis maps to class I MHC genes—a model for MHC/disease associations

scientific article published in Nature

T Helpers may be Sensitized by Antigen-Specifically Altered Structures, which are Coded by the I Region of the H-2 Gene Complex ⬇️

scientific article published on 01 January 1976

T and B cell tolerance and responses to viral antigens in transgenic mice: implications for the pathogenesis of autoimmune versus immunopathological disease

scientific article published on August 1991

T cell development in CD8-/- mice. Thymic positive selection is biased toward the helper phenotype.

scientific article published in October 1995

T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides

scientific article published in August 1993

T cell priming versus T cell tolerance induced by synthetic peptides

scientific article

T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice.

scientific article

T cell-dependent IFN-gamma exerts an antiviral effect in the central nervous system but not in peripheral solid organs

scientific article published in March 1993

T cell-independent type I antibody response against B cell epitopes expressed repetitively on recombinant virus particles ⬇️

scientific article published on August 4, 1998

T cell-mediated hepatitis in mice infected with lymphocytic choriomeningitis virus. Liver cell destruction by H-2 class I-restricted virus-specific cytotoxic T cells as a physiological correlate of the 51Cr-release assay?

scientific article

T cell-mediated immune responses of lupus-prone BXSB mice and other murine strains ⬇️

scientific article published on August 1, 1979

T cells causing immunological disease

scientific article published on January 1, 1992

T cells causing immunological disease: immunopathology or autoimmunity? ⬇️

scientific article published on March 1, 1992

T helper cell unresponsiveness: Rapid induction in antigen-transgenic and reversion in non-transgenic mice

scientific article published on 01 December 1994

T helper cell-independent neutralizing B cell response against vesicular stomatitis virus: role of antigen patterns in B cell induction?

scientific article published in December 1995

T-Cell-Mediated Immunopathology in Viral Infections ⬇️

scientific article published on January 1, 1974

T-cell antigen receptors with identical variable regions but different diversity and joining region gene segments have distinct specificities but cross-reactive idiotypes

scientific article

T-cell immunoincompetence in allogeneic chimerism

scientific article published on 01 April 1992

T-cell independent IgM and enduring protective IgG antibodies induced by chimeric measles viruses ⬇️

scientific article published on August 1, 1998

T-cell lineages, repertoire selection and tolerance induction

scientific article published on August 1988

T-cell reactivity and tolerance to Mlsa-encoded antigens

scientific article published on February 1989

T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens

scientific article published on March 1988

T-cell-mediated immunopathology versus direct cytolysis by virus: implications for HIV and AIDS.

scientific article published on June 1994

T-independent activation of B cells by vesicular stomatitis virus: no evidence for the need of a second signal

scientific article published in March 1996

TAP1-independent loading of class I molecules by exogenous viral proteins

scientific article published on 01 June 1995

Target antigens for H-2-restricted vesicular stomatitis virus-specific cytotoxic T cells ⬇️

scientific article published on August 1, 1978

Targeted inactivation of the tetraspanin CD37 impairs T-cell-dependent B-cell response under suboptimal costimulatory conditions

scientific journal article

The 1995 Albert Lasker Medical Research Award. MHC-restricted T-cell recognition. The basis of immune surveillance

scientific article published in October 1995

The Concept That Surveillance of Self Is Mediated Via the Same Set of Genes That Determines Recognition of Allogenic Cells ⬇️

scientific article published on January 1, 1977

The Impact of Variation in the Number of CD8+T-Cell Precursors on the Outcome of Virus Infection ⬇️

scientific article published on October 10, 1998

The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1996. Cellular immune recognition and the biological role of major transplantation antigens

scientific article published in November 1997

The challenges of an HIV vaccine enterprise

scientific article

The discovery of MHC restriction

scientific article published on January 1997

The influence of antigen organization on B cell responsiveness

scientific article

The influence of virus structure on antibody responses and virus serotype formation

scientific article

The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help ⬇️

scientific article published on March 1, 1978

The role of antibodies in natural and acquired resistance of mice to vesicular stomatitis virus

scientific article

The role of antibody concentration and avidity in antiviral protection.

scientific article

The role of antigen in maintaining T cell memory.

scientific article published in January 1994

The role of somatic mutation in the generation of the protective humoral immune response against vesicular stomatitis virus.

scientific article published in December 1996

The roles of perforin- and Fas-dependent cytotoxicity in protection against cytopathic and noncytopathic viruses

scientific article published in December 1995

Thymic MHC class I gene regulation of susceptibility to lymphocytic choriomeningitis

scientific article published on 01 November 1990

Thymic reconstitution of nude F1 mice with one or both parental thymus grafts ⬇️

scientific article published on September 19, 1979

Thymic selection of H-2-incompatible bone marrow cells in SCID mice. Differences in T help for induction of B cell IgG responses versus cytotoxic T cells

scientific article published on September 1988

Thymus Function and Reconstitution of Immunodeficiency ⬇️

scientific article published on January 26, 1978

Thymus and Lymphohemopoietic Cells: Their Role in T Cell Maturation in Selection of T Cells' H-2-Restriction-Specificity and in H-2 Linked Ir Gene Control ⬇️

scientific article published on January 1, 1978

Thymus differentiation and T-cell specificity in nu/nu +/+ mouse aggregation chimaeras

scientific article

Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice

Tolerance induction by clonal deletion of CD4+8+ thymocytes in vitro does not require dedicated antigen-presenting cells

scientific article published on 01 March 1993

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

scientific article

Tolerance to Mlsa by clonal deletion of V beta 6+ T cells in bone marrow and thymus chimeras

scientific article published on 01 January 1989

Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

scientific article published on 16 January 2005

Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice.

scientific article

Transgenic animal models for virus-induced autoimmune diseases

scientific article

Transplantation antigens: biological function and role as disease determinants

scientific article published on 01 November 1982

Transplantation tolerance from a historical perspective

scientific article

Treatment with anti-tumor necrosis factor alpha does not influence the immune pathological response against lymphocytic choriomeningitis virus

scientific article published in January 1990

Treatment with high doses of anti-IgM prevents, but with lower doses accelerates autoimmune disease in (NZW x BXSB)F1 hybrid mice.

scientific article

Tumor necrosis factor alpha in cerebrospinal fluid during bacterial, but not viral, meningitis. Evaluation in murine model infections and in patients

scientific article

Uncertainties - discrepancies in immunology

scientific article

Unimpaired first-set and second-set skin graft rejection in agammaglobulinemic mice

scientific article published on 01 June 1988

Vaccination for Disease ⬇️

scientific article published on January 11, 1991

Vaccination or tolerance to prevent diabetes

scientific article published on 01 December 1992

Vaccination with a synthetic peptide modulates lymphocytic choriomeningitis virus-mediated immunopathology ⬇️

scientific article published on February 1, 1992

Vaccination with two different vaccinia recombinant viruses: long-term inhibition of secondary vaccination

scientific article published on 01 January 1993

Variable Immune Response Against a Developmentally Regulated Self-Antigen

scientific article published on 01 February 1999

Vesicular stomatitis virus Indiana glycoprotein as a T-cell-dependent and -independent antigen

scientific article published on June 1994

Viral and Bacterial Infections Interfere with Peripheral Tolerance Induction and Activate CD8+ T Cells to Cause Immunopathology ⬇️

scientific article published on March 2, 1998

Viral escape and the failure of cellular immune responses

scientific article

Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo ⬇️

scientific article published on August 16, 1990

Viral escape from the neutralizing antibody response: the lymphocytic choriomeningitis virus model.

scientific article published in April 2001

Viral immunopathology. Introduction

scientific article published on January 1995

Viral persistence in vivo through selection of neutralizing antibody-escape variants.

scholarly article

Virally induced immunosuppression

scientific article published on August 1, 1992

Virus neutralization by germ-line vs. hypermutated antibodies

scientific article published on August 2000

Virus or a hapten-carrier complex can activate autoreactive B cells by providing linked T help.

scientific article

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

scientific article published in April 1993

Virus-Immune Cytotoxic T Cells are Sentized to by Virus Specifically Altered Structures Coded for in H-2K or H-2D: A Biological Role for Major Histocompatibility Antigens ⬇️

scientific article published on January 1, 1976

Virus-induced acquired immune suppression by cytotoxic T cell-mediated immunopathology

scientific article published on November 1, 1992

Virus-induced autoantibody response to a transgenic viral antigen

scientific article published in May 1990

Virus-induced immune deficiency disease AIDS: direct pathogenic effect of the virus or immunopathology?

scientific article published in January 1994

Virus-induced transient bone marrow aplasia: major role of interferon-alpha/beta during acute infection with the noncytopathic lymphocytic choriomeningitis virus

scientific article

Virus-specific T-cell-mediated cytotoxicity across the H–2 barrier to virus-altered alloantigen ⬇️

scientific article published on May 13, 1976

Virus-specific cytotoxic T cell-mediated lysis of lymphocytes in vitro and in vivo.

scientific article

Virus-specific major MHC class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection ⬇️

scientific article published on January 1, 1998

Virus-specific proliferative T-cell responses: parameters and specificity

scientific article

Virus-triggered AIDS: a T-cell-mediated immunopathology?

scientific article published on December 1988

Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure

scientific article published on September 1991

Virus-triggered immune suppression in mice caused by virus-specific cytotoxic T cells

scientific article

Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts

scientific article published on April 1996

What can we learn about human immunodeficiency virus infection from a study of lymphocytic choriomeningitis virus? ⬇️

scientific article published on October 1, 1997

What if protective immunity is antigen-driven and not due to so-called "memory" B and T cells?

scientific article published in May 2018

What is missing in immunology to understand immunity?

scientific article

[Autoimmune diseases]

scientific article published on 01 April 1993

[Model concepts on the development of so-called autoimmune diseases]

scientific article published on 01 February 1993

Paulina is supported by:

About Paulina

Help