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List of works by Susan E. Critchlow

3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers

scientific article published on 26 November 2018

A functional analysis of 180 cancer cell lines reveals conserved intrinsic metabolic programs

scientific article published in November 2022

AZD3514: A Small Molecule That Modulates Androgen Receptor Signaling and Function In Vitro and In Vivo ⬇️

scientific article published on July 16, 2013

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

scientific article

Acetyl-coA synthetase 2 promotes acetate utilization and maintains cell growth under metabolic stress.

scientific article published on 28 May 2014

Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer

scientific article

Combined Inhibition of PI3Kβ and mTOR Inhibits Growth of PTEN-null Tumors

scientific article published on 10 August 2018

Inhibiting PI3Kβ with AZD8186 Regulates Key Metabolic Pathways in PTEN-Null Tumors

scientific article published on 2 October 2017

Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.

scientific article

Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma

scientific article published on 6 April 2017

Inhibition of monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport

scientific article

Investigation of the role of Ras and other signaling kinases on the regulation of pyruvate dehydrogenase complex activity

Leptin, BMI, and a Metabolic Gene Expression Signature Associated with Clinical Outcome to VEGF Inhibition in Colorectal Cancer

scientific article published on 24 November 2015

Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt's lymphoma anti-tumor activity

scientific article published on 25 May 2017

Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging

scientific article published on 26 April 2018

Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters

scientific article published in Scientific Reports

Targeted Metabolic Profiling of the Tg197 Mouse Model Reveals Itaconic Acid as a Marker of Rheumatoid Arthritis

scientific article published on 5 October 2016

Targeted profiling of polar intracellular metabolites using ion-pair-high performance liquid chromatography and -ultra high performance liquid chromatography coupled to tandem mass spectrometry: applications to serum, urine and tissue extracts

scientific article published on 12 May 2014

The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

scientific article published on 07 January 2021

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