List of works - Lothar Brecker

2H-Azirines from a concerted addition of alkylcarbenes to nitrile groups

scientific article published in May 2010

A novel beta-diketone-cleaving enzyme from Acinetobacter johnsonii: acetylacetone 2,3-oxygenase

scientific article published in September 2002

A novel concept for detoxification: complexation between aconitine and liquiritin in a Chinese herbal formula ('Sini Tang').

scientific article

A revised classification of the sister tribes Palicoureeae and Psychotrieae (Rubiaceae) indicates genus-specific alkaloid accumulation

scientific article published in 2021

Acetylacetone-cleaving enzyme Dke1: a novel C-C-bond-cleaving enzyme from Acinetobacter johnsonii

scientific article

Acid-base catalysis in Leuconostoc mesenteroides sucrose phosphorylase probed by site-directed mutagenesis and detailed kinetic comparison of wild-type and Glu237-->Gln mutant enzymes

scientific article published on May 2007

Alcoholysis of naturally occurring imides: misleading interpretation of antifungal activities

scientific article published on August 2010

Alkaloid and iridoid glucosides from Palicourea luxurians (Rubiaceae: Palicoureeae) indicate tryptamine- and tryptophan-iridoid alkaloid formation apart the strictosidine pathway

scientific article published on 19 February 2020

Anti-angiogenic effects and mechanisms of zerumin A from Alpinia caerulea

scientific article published on 25 October 2011

Binding pattern of intermediate UDP-4-keto-xylose to human UDP-xylose synthase: Synthesis and STD NMR of model keto-saccharides

scientific article published on 5 November 2016

Bisecting Galactose as a Feature of N-Glycans of Wild-type and Mutant Caenorhabditis elegans

scientific article published on 22 May 2015

Bromination and accompanying rearrangement of the polycyclic oxetane 2,4-oxytwistane

scientific article published on 03 September 2014

Candida tenuis xylose reductase catalysed reduction of acetophenones: the effect of ring-substituents on catalytic efficiency

scientific article published on 05 July 2011

Candida tenuis xylose reductase catalyzed reduction of aryl ketones for enantioselective synthesis of active oxetine derivatives.

scientific article

Catalytic mechanism of human UDP-glucose 6-dehydrogenase: in situ proton NMR studies reveal that the C-5 hydrogen of UDP-glucose is not exchanged with bulk water during the enzymatic reaction ⬇️

scientific article published on April 2, 2012

Characterization and scope of S-layer protein O-glycosylation in Tannerella forsythia

scientific article published on 12 September 2011

Chemical constituents of Clausena lenis

scientific article published on 06 April 2020

Chemical structure of Bacteriovorax stolpii lipid A.

scientific article

Chemodiversity of tryptamine-derived alkaloids in six Costa Rican Palicourea species (Rubiaceae-Palicoureeae).

scientific article

Chiral resolution through stereoselective transglycosylation by sucrose phosphorylase: application to the synthesis of a new biomimetic compatible solute, (R)-2-O-α-D-glucopyranosyl glyceric acid amide

scientific article published on January 2014

Configurational stability of oxymethyllithiums as intermediates in intramolecular rearrangements

scientific article published on 01 January 2007

Controllable selective functionalization of a cavitand via solid state photolysis of an encapsulated phenyl azide

scientific article published on 01 July 2009

Cope rearrangement versus a novel tandem retro-Diels-Alder-Diels-Alder reaction with role reversal

scientific article published on 01 January 2007

Diastereoselective Synthesis of Glycosyl Phosphates by Using a Phosphorylase-Phosphatase Combination Catalyst

scientific article published on 13 November 2015

Discovery and structural characterization of fucosylated oligomannosidic N-glycans in mushrooms

scientific article

Dissecting Metabolism of Leaf Nodules in Ardisia crenata and Psychotria punctata ⬇️

scientific article

Dopamine-iridoid alkaloids in Carapichea affinis (= Psychotria borucana) confirm close relationship to the vomiting root Ipecac

scholarly article by Martin Bernhard et al published June 2011 in Biochemical Systematics and Ecology

Efforts toward Distorted Spiropentanes ⬇️

scientific article published on November 5, 2010

Enzyme identification and development of a whole-cell biotransformation for asymmetric reduction of o-chloroacetophenone

article

Examining the role of phosphate in glycosyl transfer reactions of Cellulomonas uda cellobiose phosphorylase using d-glucal as donor substrate ⬇️

scientific article published on April 13, 2012

Flavonoids in Selected <i>Primula</i> Spp.: Bridging Micromorphology with Chemodiversity

scientific article published in 2012

Flavonoids in selected Primula spp.: bridging micromorphology with chemodiversity

scientific article published on 01 November 2012

Functionalized cyclobutanes via Heck cyclization

scientific article published on 27 September 2007

In situ proton NMR analysis of alpha-alkynoate biotransformations. From 'invisible' substrates to detectable metabolites

scientific article published in April 2003

In situ proton NMR study of acetyl and formyl group migration in mono-O-acyl D-glucose

scientific article published in April 2009

Inside cover: total synthesis and configurational assignment of pasteurestin a and B (Angew. Chem. Int. Ed. 48/2007)

scientific article published on 01 January 2007

Interplay of catalytic subsite residues in the positioning of α-d-glucose 1-phosphate in sucrose phosphorylase

scientific article published on 17 April 2015

Intra- and intermolecular reaction selectivities of γ-substituted adamantanylidenes

scientific article published on 12 January 2012

Iridoids as chemical markers of false ipecac (Ronabea emetica), a previously confused medicinal plant

scientific article

Kabiramide L, a new antiplasmodial trisoxazole macrolide from the spongePachastrissa nux ⬇️

scientific article published on September 12, 2012

Loganin and secologanin derived tryptamine-iridoid alkaloids from Palicourea crocea and Palicourea padifolia (Rubiaceae).

scientific article published in June 2015

Mechanistic differences among retaining disaccharide phosphorylases: insights from kinetic analysis of active site mutants of sucrose phosphorylase and alpha,alpha-trehalose phosphorylase

scientific article published on 02 February 2008

NMR study of 13C-kinetic isotope effects at 13C natural abundance to characterize oxidations and an enzyme-catalyzed reduction

New reports on flavonoids, benzoic- and chlorogenic acids as rare features in the Psychotria alliance (Rubiaceae)

scientific article published in 2016

Nuclear Magnetic Relaxation Mapping of Spin Relaxation in Electrically Stressed Glycerol

scientific article published on 24 August 2020

Nuclear magnetic resonance of lipid A--the influence of solvents on spin relaxation and spectral quality

scientific article

Orphan flavonoids and dihydrochalcones from Primula exudates.

scientific article published in August 2013

Pandanus alkaloids in Stemonaceae: finding of a plausible biogenetic origin of Stemona alkaloids.

scientific article published in September 2009

Phosphoryl transfer from α-d-glucose 1-phosphate catalyzed by Escherichia coli sugar-phosphate phosphatases of two protein superfamily types

scientific article published on 19 December 2014

Phytochemical meanings of tetrahydro-β-carboline moiety in strictosidine derivatives.

scientific article published on 18 December 2015

Probing the active site of Corynebacterium callunae starch phosphorylase through the characterization of wild-type and His334-->Gly mutant enzymes

scientific article published on 04 September 2007

Regioselective O-glucosylation by sucrose phosphorylase: a promising route for functional diversification of a range of 1,2-propanediols

scientific article published on 8 June 2010

Reversible DNA compaction induced by partial intercalation of 16-Ph-16 gemini surfactants: evidence of triple helix formation

article published in 2018

Rhamnogalacturonan II structure shows variation in the side chains monosaccharide composition and methylation status within and across different plant species

scientific article published on 05 August 2013

Selectivity issues in targeted metabolomics: Separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography.

scientific article published on November 2010

Silvaglenamin—a novel dimeric triterpene alkaloid from Aglaia silvestris

Spectroscopic studies on the molecular interactions of curcumin and piperine

scientific article published in 2020

Striking Diversification of Exudate Profiles in Selected Primula Lineages

scientific article published in May 2016

Structural and biological characterization of highly purified hepta-acyl lipid A present in the lipopolysaccharide of the Salmonella enterica sv. Minnesota Re deep rough mutant strain R595

Structural and biological characterization of highly purified hepta-acyl lipid A present in the lipopolysaccharide of the Salmonella enterica sv. Minnesota Re deep rough mutant strain R595.

scientific article

Structural and immunological properties of arabinogalactan polysaccharides from pollen of timothy grass (Phleum pratense L.).

scientific article published on 01 March 2005

Structural relationships of stemona alkaloids: assessment of species-specific accumulation trends for exploiting their biological activities

scientific article published on 08 September 2011

Structure and mechanism of human UDP-xylose synthase: evidence for a promoting role of sugar ring distortion in a three-step catalytic conversion of UDP-glucuronic acid

scientific article published on 18 July 2012

Structure of a highly phosphorylated lipopolysaccharide core in the Delta algC mutants derived from Pseudomonas aeruginosa wild-type strains PAO1 (serogroup O5) and PAC1R (serogroup O3).

scientific article published in November 2003

Structure-reactivity relationships: reactions of a 5-substituted aziadamantane in a resorcin[4]arene-based cavitand

scientific article published in January 2010

Studying non-covalent enzyme carbohydrate interactions by STD NMR.

scientific article

Supramolecular recognition and structural elucidation of inclusion complexes of an achiral carbene precursor in beta- and permethylated beta-cyclodextrin

scientific article published on 01 June 2004

Synthesis and conformation of chiral biheteroaryls

scientific article published on 23 March 2011

Synthesis, characterization, and antioxidant activity of Zn2+ and Cu2+ coordinated polyhydroxychalcone complexes

scientific article published on 29 August 2016

The obligate predatory Bdellovibrio bacteriovorus possesses a neutral lipid A containing alpha-D-Mannoses that replace phosphate residues: similarities and differences between the lipid As and the lipopolysaccharides of the wild type strain B. [...]

scientific article

The role of PKAc1 in gene regulation and trichodimerol production in Trichoderma reesei

scientific article published on 10 September 2019

Total synthesis and configurational assignment of pasteurestin A and B

scientific article published on 01 January 2007

Unusual compounds from exudates of Dionysia diapensifolia and D. gaubae var. megalantha (Primulaceae)

scientific article published on 01 May 2011

Ursane-type triterpenoids, steroids and phenolics from the stem bark and leaves of Nauclea orientalis (L.) L. (Rubiaceae)

scientific article published in 2022

Van der Waals versus hydrogen-bonding forces in a crystalline analog of cellotetraose: cyclohexyl 4'-O-cyclohexyl beta-D-cellobioside cyclohexane solvate.

scientific article published in December 2008

Xanthones, biflavanones and triterpenes from Pentadesma grandifolia (Clusiaceae): structural determination and bioactivity

scientific article published on July 1, 2010

List of works by Lothar Brecker

2H-Azirines from a concerted addition of alkylcarbenes to nitrile groups

A novel beta-diketone-cleaving enzyme from Acinetobacter johnsonii: acetylacetone 2,3-oxygenase

A novel concept for detoxification: complexation between aconitine and liquiritin in a Chinese herbal formula ('Sini Tang').

A revised classification of the sister tribes Palicoureeae and Psychotrieae (Rubiaceae) indicates genus-specific alkaloid accumulation

Acetylacetone-cleaving enzyme Dke1: a novel C-C-bond-cleaving enzyme from Acinetobacter johnsonii

Acid-base catalysis in Leuconostoc mesenteroides sucrose phosphorylase probed by site-directed mutagenesis and detailed kinetic comparison of wild-type and Glu237-->Gln mutant enzymes

Alcoholysis of naturally occurring imides: misleading interpretation of antifungal activities

Alkaloid and iridoid glucosides from Palicourea luxurians (Rubiaceae: Palicoureeae) indicate tryptamine- and tryptophan-iridoid alkaloid formation apart the strictosidine pathway

Anti-angiogenic effects and mechanisms of zerumin A from Alpinia caerulea

Binding pattern of intermediate UDP-4-keto-xylose to human UDP-xylose synthase: Synthesis and STD NMR of model keto-saccharides

Bisecting Galactose as a Feature of N-Glycans of Wild-type and Mutant Caenorhabditis elegans

Bromination and accompanying rearrangement of the polycyclic oxetane 2,4-oxytwistane

Candida tenuis xylose reductase catalysed reduction of acetophenones: the effect of ring-substituents on catalytic efficiency

Candida tenuis xylose reductase catalyzed reduction of aryl ketones for enantioselective synthesis of active oxetine derivatives.

Catalytic mechanism of human UDP-glucose 6-dehydrogenase: in situ proton NMR studies reveal that the C-5 hydrogen of UDP-glucose is not exchanged with bulk water during the enzymatic reaction ⬇️

Characterization and scope of S-layer protein O-glycosylation in Tannerella forsythia

Chemical constituents of Clausena lenis

Chemical structure of Bacteriovorax stolpii lipid A.

Chemodiversity of tryptamine-derived alkaloids in six Costa Rican Palicourea species (Rubiaceae-Palicoureeae).

Chiral resolution through stereoselective transglycosylation by sucrose phosphorylase: application to the synthesis of a new biomimetic compatible solute, (R)-2-O-α-D-glucopyranosyl glyceric acid amide

Configurational stability of oxymethyllithiums as intermediates in intramolecular rearrangements

Controllable selective functionalization of a cavitand via solid state photolysis of an encapsulated phenyl azide

Cope rearrangement versus a novel tandem retro-Diels-Alder-Diels-Alder reaction with role reversal

Diastereoselective Synthesis of Glycosyl Phosphates by Using a Phosphorylase-Phosphatase Combination Catalyst

Discovery and structural characterization of fucosylated oligomannosidic N-glycans in mushrooms

Dissecting Metabolism of Leaf Nodules in Ardisia crenata and Psychotria punctata ⬇️

Dopamine-iridoid alkaloids in Carapichea affinis (= Psychotria borucana) confirm close relationship to the vomiting root Ipecac

Efforts toward Distorted Spiropentanes ⬇️

Enzyme identification and development of a whole-cell biotransformation for asymmetric reduction of o-chloroacetophenone

Examining the role of phosphate in glycosyl transfer reactions of Cellulomonas uda cellobiose phosphorylase using d-glucal as donor substrate ⬇️

Flavonoids in Selected <i>Primula</i> Spp.: Bridging Micromorphology with Chemodiversity

Flavonoids in selected Primula spp.: bridging micromorphology with chemodiversity

Functionalized cyclobutanes via Heck cyclization

In situ proton NMR analysis of alpha-alkynoate biotransformations. From 'invisible' substrates to detectable metabolites

In situ proton NMR study of acetyl and formyl group migration in mono-O-acyl D-glucose

Inside cover: total synthesis and configurational assignment of pasteurestin a and B (Angew. Chem. Int. Ed. 48/2007)

Interplay of catalytic subsite residues in the positioning of α-d-glucose 1-phosphate in sucrose phosphorylase

Intra- and intermolecular reaction selectivities of γ-substituted adamantanylidenes

Iridoids as chemical markers of false ipecac (Ronabea emetica), a previously confused medicinal plant

Kabiramide L, a new antiplasmodial trisoxazole macrolide from the spongePachastrissa nux ⬇️

Loganin and secologanin derived tryptamine-iridoid alkaloids from Palicourea crocea and Palicourea padifolia (Rubiaceae).

Mechanistic differences among retaining disaccharide phosphorylases: insights from kinetic analysis of active site mutants of sucrose phosphorylase and alpha,alpha-trehalose phosphorylase

NMR study of 13C-kinetic isotope effects at 13C natural abundance to characterize oxidations and an enzyme-catalyzed reduction

New reports on flavonoids, benzoic- and chlorogenic acids as rare features in the Psychotria alliance (Rubiaceae)

Nuclear Magnetic Relaxation Mapping of Spin Relaxation in Electrically Stressed Glycerol

Nuclear magnetic resonance of lipid A--the influence of solvents on spin relaxation and spectral quality

Orphan flavonoids and dihydrochalcones from Primula exudates.

Pandanus alkaloids in Stemonaceae: finding of a plausible biogenetic origin of Stemona alkaloids.

Phosphoryl transfer from α-d-glucose 1-phosphate catalyzed by Escherichia coli sugar-phosphate phosphatases of two protein superfamily types

Phytochemical meanings of tetrahydro-β-carboline moiety in strictosidine derivatives.

Probing the active site of Corynebacterium callunae starch phosphorylase through the characterization of wild-type and His334-->Gly mutant enzymes

Regioselective O-glucosylation by sucrose phosphorylase: a promising route for functional diversification of a range of 1,2-propanediols

Reversible DNA compaction induced by partial intercalation of 16-Ph-16 gemini surfactants: evidence of triple helix formation

Rhamnogalacturonan II structure shows variation in the side chains monosaccharide composition and methylation status within and across different plant species

Selectivity issues in targeted metabolomics: Separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography.

Silvaglenamin—a novel dimeric triterpene alkaloid from Aglaia silvestris

Spectroscopic studies on the molecular interactions of curcumin and piperine

Striking Diversification of Exudate Profiles in Selected Primula Lineages

Structural and biological characterization of highly purified hepta-acyl lipid A present in the lipopolysaccharide of the Salmonella enterica sv. Minnesota Re deep rough mutant strain R595

Structural and biological characterization of highly purified hepta-acyl lipid A present in the lipopolysaccharide of the Salmonella enterica sv. Minnesota Re deep rough mutant strain R595.

Structural and immunological properties of arabinogalactan polysaccharides from pollen of timothy grass (Phleum pratense L.).

Structural relationships of stemona alkaloids: assessment of species-specific accumulation trends for exploiting their biological activities

Structure and mechanism of human UDP-xylose synthase: evidence for a promoting role of sugar ring distortion in a three-step catalytic conversion of UDP-glucuronic acid

Structure of a highly phosphorylated lipopolysaccharide core in the Delta algC mutants derived from Pseudomonas aeruginosa wild-type strains PAO1 (serogroup O5) and PAC1R (serogroup O3).

Structure-reactivity relationships: reactions of a 5-substituted aziadamantane in a resorcin[4]arene-based cavitand

Studying non-covalent enzyme carbohydrate interactions by STD NMR.

Supramolecular recognition and structural elucidation of inclusion complexes of an achiral carbene precursor in beta- and permethylated beta-cyclodextrin

Synthesis and conformation of chiral biheteroaryls

Synthesis, characterization, and antioxidant activity of Zn2+ and Cu2+ coordinated polyhydroxychalcone complexes

The obligate predatory Bdellovibrio bacteriovorus possesses a neutral lipid A containing alpha-D-Mannoses that replace phosphate residues: similarities and differences between the lipid As and the lipopolysaccharides of the wild type strain B. [...]

The role of PKAc1 in gene regulation and trichodimerol production in Trichoderma reesei

Total synthesis and configurational assignment of pasteurestin A and B

Unusual compounds from exudates of Dionysia diapensifolia and D. gaubae var. megalantha (Primulaceae)

Ursane-type triterpenoids, steroids and phenolics from the stem bark and leaves of Nauclea orientalis (L.) L. (Rubiaceae)

Van der Waals versus hydrogen-bonding forces in a crystalline analog of cellotetraose: cyclohexyl 4'-O-cyclohexyl beta-D-cellobioside cyclohexane solvate.

Xanthones, biflavanones and triterpenes from Pentadesma grandifolia (Clusiaceae): structural determination and bioactivity