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Authors whose works are in public domain in at least one jurisdiction

List of works by Raghubir Prasad Sharma

Alteration of major cytokines produced by mitogen-activated peritoneal macrophages and splenocytes in T-2 toxin-treated male CD-1 mice ⬇️

scientific article published on February 15, 1997

Aluminum disrupts the pro-inflammatory cytokine/neurotrophin balance in primary brain rotation-mediated aggregate cultures: possible role in neurodegeneration

journal article published in 2003

Aluminum maltolate-induced cytotoxicity in neuro-2a cells involves apoptosis and necrosis ⬇️

abstract published in 2003

Aluminum-induced neurodegeneration involves differential regulation of proinflammatory cytokine and neurotrophin gene expression ⬇️

abstract published in 2003

Aluminum-maltolate induces apoptosis and necrosis in neuro-2a cells: potential role for p53 signaling.

scientific article published on 10 November 2004

Amelioration of fumonisin B1 hepatotoxicity in mice by depletion of T cells with anti-Thy-1.2.

scientific article published on 18 April 2006

Augmented fumonisin B1 toxicity in co-cultures: evidence for crosstalk between macrophages and non-parenchymatous liver epithelial cells involving proinflammatory cytokines

scientific article published in October 2004

Cadmium-induced apoptosis in murine macrophages is antagonized by antioxidants and caspase inhibitors

scientific article published on June 2006

Calcium-mediated activation of c-Jun NH2-terminal kinase (JNK) and apoptosis in response to cadmium in murine macrophages

scientific article published on 14 July 2004

Carcinogenicity and mechanism of action of fumonisin B1: a mycotoxin produced by Fusarium moniliforme (= F. verticillioides).

scientific article published in January 2002

Ceramide synthase inhibition by fumonisin B1 treatment activates sphingolipid-metabolizing systems in mouse liver

scientific article published on 07 September 2006

Characterization of heterologously expressed recombinant retinoic acid receptors with natural or synthetic retinoids

scientific article published on 01 October 1994

Cytotoxicity of inorganic mercury in murine T and B lymphoma cell lines: involvement of reactive oxygen species, Ca(2+) homeostasis, and cytokine gene expression

scientific article

Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1.

scientific article published in February 2001

Decreased membrane fluidity and hyperpolarization in aluminum-treated PC-12 cells correlates with increased production of cellular oxidants

journal article published in 2005

Deletion of IFN-y reduces fumonisin-induced hepatoxicity in mice via alterations in inflammatory cytokines and apoptic factors

journal article published in 2003

Demonstration of in-situ apoptosis in mouse liver and kidney after short-term repeated exposure to fumonisin B1 ⬇️

scientific article published on 01 November 1997

Disruption of sphingolipid homeostasis by myriocin, a mycotoxin, reduces thymic and splenic T-lymphocyte populations

journal article published in 2004

Disruption of sphingolipid metabolism in small intestines, liver and kidney of mice dosed subcutaneously with fumonisin B(1).

scientific article published in September 2000

Early fumonisin B1 toxicity in relation to disrupted sphingolipid metabolism in male BALB/c mice ⬇️

scientific article published on January 1, 1998

Effect of cadmium on P53 and mitogen-activated protein kinases in a murine macrophage cell line: relation to apoptosis ⬇️

abstract published in 2003

Effects of T-2 toxin and its congeners on membrane functions of cultured human fibroblasts

scientific article published on 01 March 1991

Effects of aflatoxin B1 and T-2 toxin on the granulocyte-macrophage progenitor cells in mouse bone marrow cultures

scientific article published on 01 January 1994

Effects of endotoxin and tumor necrosis factor alpha on regional brain neurotransmitters in mice

scientific article published on 01 January 1999

Endotoxin exposure alters brain and liver effects of fumonisin B1 in BALB/c mice: implication of blood brain barrier

scientific article published in September 2005

Extracellular signal-regulated kinase-signaling-dependent G2/M arrest and cell death in murine macrophages by cadmium

scientific article published in December 2005

Fumonisin B(1) alters sphingolipid metabolism and tumor necrosis factor alpha expression in heart and lung of mice

scientific article published in September 2002

Fumonisin B(1)-induced alterations in cytokine expression and apoptosis signaling genes in mouse liver and kidney after an acute exposure

scientific article

Fumonisin B1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride

scientific article published in February 2005

Fumonisin B1 induces necrotic cell death in BV-2 cells and murine cultured astrocytes and is antiproliferative in BV-2 cells while N2A cells and primary cortical neurons are resistant

scientific article published on 6 July 2005

Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-κB and tumor necrosis factor α in LLC-PK1 cells ⬇️

scientific article published on October 25, 2003

Fumonisin B1-induced increases in neurotransmitter metabolite levels in different brain regions of BALB/c mice.

scientific article published in October 1998

Fumonisin B1-induced localized activation of cytokine network in mouse liver

scientific article published in October 2002

Fumonisin B1-induced neurodegeneration in mice after intracerebroventricular infusion is concurrent with disruption of sphingolipid metabolism and activation of proinflammatory signaling

scientific article published in March 2005

Fumonisin hepatotoxicity is reduced in mice carrying the human tumour necrosis factor alpha transgene

scientific article published on 01 July 2000

Fumonisin toxicity in a transgenic mouse model lacking the mdr1a/1b P-glycoprotein genes

scientific article published in March 2000

Fumonisin-induced tumor necrosis factor-alpha expression in a porcine kidney cell line is independent of sphingoid base accumulation induced by ceramide synthase inhibition

scientific article

Gender-dependent immunosuppression following subacute exposure to fumonisin B1.

scientific article

Gender-related differences in subacute fumonisin B1 hepatotoxicity in BALB/c mice

scientific article

Histochemical localization of retinoic acid receptors in the developing hamster fetus

scientific article published on September 1995

Increase in dopamine metabolites in murine striatum after oral exposure to inorganic but not organic form of selenium

scientific article published on 01 July 2000

Increased expression of CD95-ligand and other apoptotic signaling factors by fumonisin B1, a hepatotoxic mycotoxin, in livers of mice lacking tumor necrosis factor α ⬇️

scientific article published on 01 December 2003

Increased production of proinflammatory cytokines by murine macrophages following oral exposure to sodium selenite but not to seleno-L-methionine

scientific article

Increased proinflammatory cytokines production by ergotamine in male BALB/c mice

scientific article published on 01 October 1999

Increased responsiveness to intravenous lipopolysaccharide challenge in steers grazing endophyte-infected tall fescue compared with steers grazing endophyte-free tall fescue

scientific article published on November 1999

Increased susceptibility of renal epithelial cells to TNFalpha-induced apoptosis following treatment with fumonisin B1

scientific article published on 01 June 2003

Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase

scientific article

Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression

scientific article published on May 2004

Inhibition of serine palmitoyltransferase by myriocin, a natural mycotoxin, causes induction of c-myc in mouse liver

journal article published in 2004

Inhibition of tumor necrosis factor alpha signaling by anti-tumor necrosis factor alpha antibodies and pentoxifylline is unable to prevent fumonisin hepatotoxicity in mice

scientific article published in September 2005

Localization of retinoic acid receptors in anterior-human embryo

scientific article published on 01 June 1995

Lupus-prone NZBWF1/J mice, defective in cytokine signaling, are resistant to fumonisin hepatotoxicity despite accumulation of liver sphinganine

scientific article

Mercury alters endotoxin-induced inflammatory cytokine expression in liver: differential roles of p38 and extracellular signal-regulated mitogen-activated protein kinases

scientific article

Mercury inhibits nitric oxide production but activates proinflammatory cytokine expression in murine macrophage: differential modulation of NF-kappaB and p38 MAPK signaling pathways

scientific article published on August 2002

Mercury-induced apoptosis and necrosis in murine macrophages: role of calcium-induced reactive oxygen species and p38 mitogen-activated protein kinase signaling

scientific article published in April 2004

Mice lacking both TNFalpha receptors show increased constitutive expression of IFNgamma: a possible reason for lack of protection from fumonisin B1 hepatotoxicity

scientific article published on 01 June 2006

Modification of the retinoic acid signaling pathway by the catalytic subunit of protein kinase-A.

scientific article published on April 1993

Modulation of tumor necrosis factor alpha expression in mouse brain after exposure to aluminum in drinking water

scientific article

Myriocin prevents fumonisin B1-induced sphingoid base accumulation in mice liver without ameliorating hepatotoxicity

scientific article published in June 2005

Myriocin, a serine palmitoyltransferase inhibitor, alters regional brain neurotransmitter levels without concurrent inhibition of the brain sphingolipid biosynthesis in mice

scientific article

Oral exposure to inorganic mercury alters T lymphocyte phenotypes and cytokine expression in BALB/c mice

scientific article published on 20 August 2003

Oral exposure to inorganic mercury alters T-lymphocyte phenotypes and cytokine gene expression in BALB/C Mice ⬇️

abstract published in 2003

Paradoxical role of tumor necrosis factor alpha in fumonisin-induced hepatotoxicity in mice

scientific article published in December 2002

Persistence and reversibility of the elevation in free sphingoid bases induced by fumonisin inhibition of ceramide synthase

scientific article

Pharmacological antagonism of fumonisin B1 cytotoxicity in porcine renal epithelial cells (LLC-PK1): a model for reducing fumonisin-induced nephrotoxicity in vivo

scientific article

Physiological responses of a natural antioxidant flavonoid mixture, silymarin, in BALB/c mice: III. Silymarin inhibits T-lymphocyte function at low doses but stimulates inflammatory processes at high doses

scientific article published on 01 January 2003

Physiological responses to a natural antioxidant flavonoid mixture, silymarin, in BALB/c mice: I induction of transforming growth factor beta1 and c-myc in liver with marginal effects on other genes

scientific article published in August 2002

Physiological responses to a natural antioxidant flavonoid mixture, silymarin, in BALB/c mice: II. alterations in thymic differentiation correlate with changes in c-myc gene expression

scientific article published on 01 November 2002

Region-specific decrease of dopamine and its metabolites in brains of mice given ergotamine

scientific article

S-adenosylmethionine or 5'-methylthioadenosine are unable to prevent fumonisin B1 hepatotoxicity in mice despite increased oxidation in liver

scientific article published in November 2006

Selective and transient activation of protein kinase C alpha by fumonisin B1, a ceramide synthase inhibitor mycotoxin, in cultured porcine renal cells

scientific article

Selenium attenuates lipopolysaccharide-induced oxidative stress responses through modulation of p38 MAPK and NF-kappaB signaling pathways

scientific article published on February 2004

Selenium inhibits lipopolysaccharide-induced nitric oxide production by attenuation of NF[kappa]B and p38 MAPK pathways in murine macrophages ⬇️

abstract published in 2003

Serine palmitoyltransferase inhibition reverses anti-proliferative effects of ceramide synthase inhibition in cultured renal cells and suppresses free sphingoid base accumulation in kidney of BALBc mice ⬇️

scientific article published on 01 April 1999

Silymarin protects against liver damage in BALB/c mice exposed to fumonisin B1 despite increasing accumulation of free sphingoid bases

scientific article published on 21 April 2004

Sodium selenite-induced apoptosis in murine B-lymphoma cells is associated with inhibition of protein kinase C-delta, nuclear factor kappaB, and inhibitor of apoptosis protein

scientific article published on 21 January 2004

Sphingoid bases and their phosphates: transient activation and delayed repression of protein kinase C isoforms and their possible involvement in fumonisin B1 cytotoxicity ⬇️

scientific article published on May 3, 2003

Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis

scientific article

Sphingosine kinase activity confers resistance to apoptosis by fumonisin B1 in human embryonic kidney (HEK-293) cells.

scientific article

Temporal expression of fumonisin B(1)-induced tumor necrosis factor-alpha and interferon gamma in mice

scientific article published in February 2002

Temporal expression of retinoic acid receptors in hamster fetus during organogenesis and alteration by retinoic acid treatment

scientific article published on May 1996

The effect of aflatoxin B1 on cytokine mRNA and corresponding protein levels in peritoneal macrophages and splenic lymphocytes

scientific article published on 01 October 1996

The mycotoxin fumonisin B1 transiently activates nuclear factor-kappaB, tumor necrosis factor alpha and caspase 3 via protein kinase Calpha-dependent pathway in porcine renal epithelial cells

scientific article published in July 2004

Tolerance to fumonisin toxicity in a mouse strain lacking the P75 tumor necrosis factor receptor

scientific article published on 01 February 2000

Transcriptional activation of a model reporter system by retinoids and retinoic acid receptor isoforms

scientific article published on January 1995

Tumor necrosis factor alpha-mediated activation of c-Jun NH(2)-terminal kinase as a mechanism for fumonisin B(1) induced apoptosis in murine primary hepatocytes

scientific article published on 01 January 2005

Tumor necrosis factor-alpha as a contributor in fumonisin B1 toxicity ⬇️

scientific article published on 01 April 1998

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