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List of works by Maureen D O'Connor-McCourt

A direct interaction between transforming growth factor (TGF)-betas and amyloid-beta protein affects fibrillogenesis in a TGF-beta receptor-independent manner

scientific article

A ligand-pseudoreceptor system based on de novo designed peptides for the generation of adenoviral vectors with altered tropism.

scientific article published on April 2008

A map of human cancer signaling

scientific article

A mass spectrometry-based plasma protein panel targeting the tumor microenvironment in patients with breast cancer ⬇️

scientific article published on November 20, 2012

A multi-strategy approach to informative gene identification from gene expression data

scientific article

A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands

scientific article

Adenovirus-delivered antisense RNA and shRNA exhibit different silencing efficiencies for the endogenous transforming growth factor-beta (TGF-beta) type II receptor

scientific article published in January 2006

Analysis of acquired resistance to metronomic oral topotecan chemotherapy plus pazopanib after prolonged preclinical potent responsiveness in advanced ovarian cancer.

scientific article

Analysis of the contribution of receptor subdomains to the cooperative binding and internalization of transforming growth factor-beta (TGF-beta) type I and type II receptors

scientific article

Assisted Design of Antibody and Protein Therapeutics (ADAPT).

scientific article published on 27 July 2017

Autoantibodies to the epidermal growth factor receptor in systemic sclerosis, lupus, and autoimmune mice

scientific article

Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling.

scientific article published on 2 December 2016

Binding and functional profiling of antibody mutants guides selection of optimal candidates as antibody drug conjugates

scientific article published on 31 December 2019

Computational selection of antibody-drug conjugate targets for breast cancer.

scientific article published on 19 December 2015

Correction to Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling

scientific article

Correction: A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands

scientific article published on 21 August 2017

Corrigendum: Identification of high-quality cancer prognostic markers and metastasisnetwork modules.

scientific article published on 31 January 2012

Development of reverse phase protein microarrays for the validation of clusterin, a mid-abundant blood biomarker

scientific article

Differential sensitivity of A549 non-small lung carcinoma cell responses to epidermal growth factor receptor pathway inhibitors

scientific article published on 07 January 2008

Differential tumor-targeting abilities of three single-domain antibody formats

scientific article

Engineering and Therapeutic Application of Single-Chain Bivalent TGF-β Family Traps ⬇️

scientific article published on May 4, 2012

Enhancement of the antagonistic potency of transforming growth factor-beta receptor extracellular domains by coiled coil-induced homo- and heterodimerization

scientific article published on 24 March 2004

Escherichia coli expression and refolding of E/K-coil-tagged EGF generates fully bioactive EGF for diverse applications

scientific article

Expression of TGF‐β type II receptor antisense RNA impairs TGF‐β signaling in vitro and promotes mammary gland differentiation in vivo ⬇️

scientific article published on December 20, 2003

Glycoproteomic analysis of two mouse mammary cell lines during transforming growth factor (TGF)-beta induced epithelial to mesenchymal transition

scientific article published on 08 January 2009

Glycoproteomic comparison of clinical triple-negative and luminal breast tumors.

scientific article published on 16 February 2015

IGFBP-4 anti-angiogenic and anti-tumorigenic effects are associated with anti-cathepsin B activity

scientific article published on May 2013

Identification and Construction of Combinatory Cancer Hallmark-Based Gene Signature Sets to Predict Recurrence and Chemotherapy Benefit in Stage II Colorectal Cancer

scientific article published on 01 January 2016

Identification of a functional site on the type I TGF-beta receptor by mutational analysis of its ectodomain

scientific article published in February 2002

Identification of high-quality cancer prognostic markers and metastasis network modules ⬇️

scientific article published on July 13, 2010

Identification of vascular breast tumor markers by laser capture microdissection and label-free LC-MS.

scientific article

Investigation of three new mouse mammary tumor cell lines as models for transforming growth factor (TGF)-beta and Neu pathway signaling studies: identification of a novel model for TGF-beta-induced epithelial-to-mesenchymal transition

scientific article

Kinetic analysis of the interactions between troponin C (TnC) and troponin I (TnI) binding peptides: evidence for separate binding sites for the 'structural' N-terminus and the 'regulatory' C-terminus of TnI on TnC

scientific article published on 01 January 2003

Kinetic analysis of the interactions between troponin C and the C-terminal troponin I regulatory region and validation of a new peptide delivery/capture system used for surface plasmon resonance

scientific article published in October 2002

Link protein has greater affinity for versican than aggrecan

scientific article (publication date: 26 March 2004)

Mitochondrion-dependent N-terminal processing of outer membrane Mcl-1 protein removes an essential Mule/Lasu1 protein-binding site

scientific article

Molecular imaging of breast tumors using a near‐infrared fluorescently labeled clusterin binding peptide ⬇️

scientific article published on January 27, 2012

Paip1 interacts with poly(A) binding protein through two independent binding motifs

scientific article

Predictive genomics: a cancer hallmark network framework for predicting tumor clinical phenotypes using genome sequencing data

scientific article

Real-time monitoring of the interactions of two-stranded de novo designed coiled-coils: effect of chain length on the kinetic and thermodynamic constants of binding

scientific article published on 01 February 2003

Roles for endothelin receptor B and BCL2A1 in spontaneous CNS metastasis of melanoma

scientific article

Signaling network assessment of mutations and copy number variations predict breast cancer subtype-specific drug targets

scientific article published on 26 September 2013

Site-directed mutagenesis of the type II TGF-beta receptor indicates a ligand-binding site distinct from that of the type II activin receptor

scientific article published on March 2002

Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase

scientific article

Structural basis of the regulation of the CbpA co-chaperone by its specific modulator CbpM

scientific article

Structures of TGF-β Receptor Complexes: Implications for Function and Therapeutic Intervention Using Ligand Traps ⬇️

scientific article published on December 1, 2011

TbetaR-II discriminates the high- and low-affinity TGF-beta isoforms via two hydrogen-bonded ion pairs

scientific article

The crystal structure and dimerization interface of GADD45γ

scientific article

The extracellular domain of the TGFbeta type II receptor regulates membrane raft partitioning.

scientific article published on 12 June 2009

Three key residues underlie the differential affinity of the TGFbeta isoforms for the TGFbeta type II receptor

scientific article published on 02 November 2005

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