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List of works by Rolf Kaiser

A genotype independent, full-genome reverse-transcription protocol for HCV genotyping and resistance testing

scientific article published on 10 April 2017

A genotypic method for determining HIV-2 coreceptor usage enables epidemiological studies and clinical decision support

scientific article published on 20 December 2016

A novel internally controlled real-time reverse transcription-PCR assay for HIV-1 RNA targeting the pol integrase genomic region

scientific article published on 26 February 2007

A pan-genotypic Hepatitis C Virus NS5A amplification method for reliable genotyping and resistance testing

scientific article published on 30 January 2019

APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1.

scientific article published on 15 May 2011

Advantages of predicted phenotypes and statistical learning models in inferring virological response to antiretroviral therapy from HIV genotype

scientific article published in January 2009

Ambulatory care for HIV-infected patients: differences in outcomes between hospital-based units and private practices: analysis of the RESINA cohort

scientific article

An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data

scientific article

Analysis of immune selection as a potential cause for the presence of cleavage site mutation 431V in treatment-naive HIV type-1 isolates ⬇️

scientific article published on January 1, 2010

Analysis of physicochemical and structural properties determining HIV-1 coreceptor usage

scientific article

Antiretroviral therapy optimisation without genotype resistance testing: a perspective on treatment history based models

scientific article

Application of Luminex Gastrointestinal Pathogen Panel to human stool samples from Côte d'Ivoire

scientific article published on 29 August 2015

Basics of the virology of HIV-1 and its replication

scientific article

Bioinformatics approach to predicting HIV drug resistance

scientific article

Bioinformatics prediction of HIV coreceptor usage

scientific article published on 01 December 2007

Changes in the HIV‐1 mutational profile before first‐line HAART in the RESINA cohort ⬇️

scientific article published on February 1, 2011

Characterisation of the epitope for a herpes simplex virus glycoprotein B-specific monoclonal antibody with high protective capacity ⬇️

scientific article published on October 8, 2010

Clinical evaluation of Rega 8: an updated genotypic interpretation system that significantly predicts HIV-therapy response

scientific article

Clinical use, efficacy, and durability of maraviroc for antiretroviral therapy in routine care: A European survey

scientific article published on 21 November 2019

Combined Analysis of the Prevalence of Drug-Resistant Hepatitis B Virus in Antiviral Therapy-Experienced Patients in Europe (CAPRE).

scientific article published on July 2015

Comparison of GB virus C, HIV, and HCV infection markers in hemophiliacs exposed to non-inactivated or inactivated factor concentrates

scientific article published in September 2005

Comparison of classifier fusion methods for predicting response to anti HIV-1 therapy

scientific article

Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients.

scientific article published in January 2006

Computational methods for the design of effective therapies against drug resistant HIV strains

scientific article

Correction: Antiretroviral Therapy Optimisation without Genotype Resistance Testing: A Perspective on Treatment History Based Models.

scientific article published on 26 April 2011

Correction: Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana

scientific article published on 11 October 2019

Declining Prevalence of HIV-1 Drug Resistance in Antiretroviral Treatment-exposed Individuals in Western Europe ⬇️

scientific article published on January 11, 2013

Detection and characterization of enteroviruses and parechoviruses in healthy people living in the South of Côte d'Ivoire

scientific article published on 5 August 2015

Detection of a genetic footprint of the sofosbuvir resistance-associated substitution S282T after HCV treatment failure

scientific article published on 8 June 2017

Detection of bocavirus DNA in nasopharyngeal aspirates of a child with bronchiolitis

scientific article published on 11 September 2006

Detection of drug resistance mutations at low plasma HIV-1 RNA load in a European multicentre cohort study ⬇️

scientific article published on May 30, 2011

Determination of Phenotypic Resistance Cutoffs From Routine Clinical Data

scientific article

Determination of drug resistance and virus typology in HIV-1-positive pediatric patients in Istanbul, Turkey

scientific article published on 28 June 2014

Development of a phenotypic susceptibility assay for HIV-1 integrase inhibitors

scientific article published on 10 October 2016

Diversity and complexity of HIV-1 drug resistance: a bioinformatics approach to predicting phenotype from genotype

scientific article

Dynamics of BKPyV reactivation and risk of hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation

scientific article published on 12 April 2017

Dynamics of Torque Teno virus viremia could predict risk of complications after allogeneic hematopoietic stem cell transplantation

scientific article published on 12 July 2017

Earlier Initiation of Antiretroviral Treatment Coincides With an Initial Control of the HIV-1 Sub-Subtype F1 Outbreak Among Men-Having-Sex-With-Men in Flanders, Belgium

article

Effects of sequence alterations on results from genotypic tropism testing

scientific article

Efficacy and safety of abacavir plus efavirenz as a salvage regimen in HIV-infected individuals after 48 weeks

scientific article published in May 2002

Efficacy of antiretroviral therapy switch in HIV-infected patients: a 10-year analysis of the EuResist Cohort.

scientific article published on 24 January 2012

Emergence and Persistence of Letermovir-Resistant Cytomegalovirus in a Patient With Primary Immunodeficiency

scientific article published on 23 August 2019

Endogenous or exogenous spreading of HIV-1 in Nordrhein-Westfalen, Germany, investigated by phylodynamic analysis of the RESINA Study cohort

scientific article published on 20 January 2012

Epidemiology of transmitted drug resistance in chronically HIV-infected patients in Germany: the RESINA study 2001-2009

scientific article published on 24 January 2012

Erratum to "Detection and characterization of enteroviruses and parechoviruses in healthy people living in the South of Côte d'Ivoire" [J. Clin. Virol. 71 (2015) 40-43].

scientific article published on 21 October 2015

Erratum zu: Nachweis einer Infektion mit Humanem Immundefizienzvirus (HIV): Serologisches Screening mit nachfolgender Bestätigungsdiagnostik durch Antikörper-basierte Testsysteme und/oder durch HIV-Nukleinsäure-Nachweis

article

Estimating HIV evolutionary pathways and the genetic barrier to drug resistance

scientific article published on 28 April 2005

Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapy

scientific article

Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates

scientific article published on 29 April 2010

Evolution of raltegravir resistance during therapy.

scientific article published on 14 May 2009

Extraction of viral nucleic acids: Comparison of five automated nucleic acid extraction platforms ⬇️

scientific article published on April 13, 2012

Failure of Dolutegravir First-Line ART with Selection of Virus Carrying R263K and G118R

scientific article published on 01 August 2019

Fifteen years of env C2V3C3 evolution in six individuals infected clonally with human immunodeficiency virus type 1.

scientific article published on November 2007

Frequent detection of cell-associated HIV-1 RNA in patients with plasma viral load <50 copies/ml

scientific article published on 01 October 2007

Functional domains of the human immunodeficiency virus type 1 Nef protein are conserved among different clades in Cameroon

scientific article published in October 2006

Geno2pheno: Estimating phenotypic drug resistance from HIV-1 genotypes

scientific article

Geno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents

scientific article

Genome Sequence of Novel Human Parechovirus Type 17.

scientific article published on 23 February 2017

Genotypic resistance testing of HCV - is there a clinical need?

scientific article published on 4 August 2016

Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis ⬇️

scientific article

Genotyping hepatitis B virus dual infections using population-based sequence data

scientific article

HIV in Turkey, a country bridging the Islamic world and Europe

scientific article published on 2 March 2014

HIV prevalence and route of transmission in Turkish immigrants living in North-Rhine Westphalia, Germany

scientific article published on 02 April 2011

HIV-1 Sub-Subtype A6: Settings for Normalised Identification and Molecular Epidemiology in the Southern Federal District, Russia

scientific article published on 22 April 2020

HIV-1 subtypes and drug resistance profiles in a cohort of heterosexual patients in Istanbul, Turkey

scientific article published on 28 April 2015

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

scientific article published on 16 September 2013

HIV-2: A summary of present standard of care and treatment options for HIV-2 infected individuals living in Western Europe

scientific article published on 30 March 2020

HIV-2EU-Supporting Standardized HIV-2 Drug-Resistance Interpretation in Europe: An Update

scientific article published on 17 July 2015

HIV-2EU: supporting standardized HIV-2 drug resistance interpretation in Europe

scientific article published on 19 February 2013

HIV-GRADE: a publicly available, rules-based drug resistance interpretation algorithm integrating bioinformatic knowledge

scientific article published on 24 January 2012

HIV/Hepatitis C Virus Co-infection among Adults Beginning Antiretroviral Therapy, Malawi

scientific article published on November 2016

Hepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery ⬇️

scientific article published on September 25, 2010

High prevalence of bevirimat resistance mutations in protease inhibitor-resistant HIV isolates

scientific article published on March 2010

How Individual Can Personalized Antiretroviral Treatment Be? Deep Salvage in an HIV-1-Infected Patient ⬇️

scientific article published on January 24, 2012

Immune-escape mutations and stop-codons in HBsAg develop in a large proportion of patients with chronic HBV infection exposed to anti-HBV drugs in Europe.

scientific article published in June 2018

Improved prediction of HIV‐1 coreceptor usage with sequence information from the second hypervariable loop of gp120

scientific article published on 01 November 2010

Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance

scientific article published in January 2007

Improved therapy-success prediction with GSS estimated from clinical HIV-1 sequences

scientific article

Inferring short-range linkage information from sequencing chromatograms

scientific article

Influence of major HIV-1 protease inhibitor resistance mutations on CTL recognition

scientific article published on 01 February 2011

Integrase inhibitor (INI) genotypic resistance in treatment-naive and raltegravir-experienced patients infected with diverse HIV-1 clades

scientific article

Learning multiple evolutionary pathways from cross-sectional data

scientific article

Longer-term effectiveness of protease-inhibitor-based second line antiretroviral therapy in four large sub-Saharan African clinics

scientific article published on 06 March 2019

Longitudinal comparison of HIV-1 plasma viral load and cellular proviral load

scientific article published on 2 November 2014

Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART: a multicohort European case-control study using centralized ultrasensitive 454 pyrosequencing

scientific article

Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana

scientific article published on 03 September 2019

Maraviroc, as a Switch Option, in HIV-1-infected Individuals With Stable, Well-controlled HIV Replication and R5-tropic Virus on Their First Nucleoside/Nucleotide Reverse Transcriptase Inhibitor Plus Ritonavir-boosted Protease Inhibitor Regimen: Wee

scientific article published on 5 April 2016

Methods for optimizing antiviral combination therapies

scientific article

Molecular Characterization and Clinical Description of Non-Polio Enteroviruses Detected in Stool Samples from HIV-Positive and HIV-Negative Adults in Ghana

scientific article published on 16 February 2020

Molecular Epidemiology of the HIV Epidemic in Three German Metropolitan Regions - Cologne/Bonn, Munich and Hannover, 1999-2016

scientific article published on 01 May 2018

Molecular epidemiology of HIV in a cohort of men having sex with men from Istanbul.

scientific article

Mtreemix: a software package for learning and using mixture models of mutagenetic trees

scientific article published on 18 January 2005

Multicenter Evaluation of Two Next-Generation HIV-1 Quantitation Assays, Aptima Quant Dx and Cobas 6800, in Comparison to the RealTie HIV-1 Reference Assay

article

Mutational patterns in the frameshift-regulating site of HIV-1 selected by protease inhibitors ⬇️

scientific article published on December 27, 2011

New findings in HCV genotype distribution in selected West European, Russian and Israeli regions

scientific article published on 24 May 2016

Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure in Indian patients.

scientific article

Only slight impact of predicted replicative capacity for therapy response prediction

scientific article

Parameters Influencing Baseline HIV-1 Genotypic Tropism Testing Related to Clinical Outcome in Patients on Maraviroc

scientific article

Persistent CMV infection after allogeneic hematopoietic stem cell transplantation in a CMV-seronegative donor-to-positive recipient constellation: Development of multidrug resistance in the absence of anti-viral cellular immunity

scientific article published on 30 November 2015

Personalized HIV therapy to control drug resistance

scientific article

Predicting HIV coreceptor usage on the basis of genetic and clinical covariates.

scientific article published in January 2007

Predicting response to antiretroviral treatment by machine learning: the EuResist project

scientific article published on 24 January 2012

Predicting the response to combination antiretroviral therapy: retrospective validation of geno2pheno-THEO on a large clinical database

scientific article published in April 2009

Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach

scientific article published on December 2011

Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients

scientific article published on 19 September 2010

Prevalence of C-terminal gag cleavage site mutations in HIV from therapy-naïve patients

scientific article published on 24 December 2008

Prevalence of anti-HBs without anti-HBc among HIV-infected adults initiating antiretroviral therapy in Lilongwe, Malawi.

scientific article

Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naïve patients

scientific article published on 4 November 2010

Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naïve patients and their impact on the virological failure

scientific article published on 17 April 2009

Primary HIV drug resistance and efficacy of first-line antiretroviral therapy guided by resistance testing

scientific article published in April 2006

Proviral DNA as a Target for HIV-1 Resistance Analysis

scientific article published on 27 June 2015

RNAemia Corresponds to Disease Severity and Antibody Response in Hospitalized COVID-19 Patients

scientific article published on 18 September 2020

Rapid Rebound of a Preexisting CXCR4-tropic Human Immunodeficiency Virus Variant After Allogeneic Transplantation With CCR5 Δ32 Homozygous Stem Cells

scientific article published on 01 February 2019

Reactivation of an occult hepatitis B virus escape mutant in an anti-HBs positive, anti-HBc negative lymphoma patient

scientific article published on 28 November 2006

RegaDB: community-driven data management and analysis for infectious diseases

scientific article

Reply to "Issues on results of the external quality assessment for proviral DNA testing of HIV-1 Tropism in the Maraviroc Switch collaborative study".

scientific article published on December 2013

Results of external quality assessment for proviral DNA testing of HIV tropism in the Maraviroc Switch collaborative study

scientific article published on 17 April 2013

Results of the first international HIV-1 coreceptor proficiency panel test

scientific article published on 10 June 2017

Risk factors associated with older age in treatment-naive HIV-positive patients

scientific article published on 24 January 2012

Risk of hepatitis C after immunoadsorption

scientific article

Seasonal influenza virus species in patient swab samples analyzed for the presence of the pandemic (H1N1) 2009 influenza virus

scientific article published on 30 September 2009

Selecting anti-HIV therapies based on a variety of genomic and clinical factors

scientific article published on July 2008

Selective pressures of HLA genotypes and antiviral therapy on human immunodeficiency virus type 1 sequence mutation at a population level

scientific article

Severe human bocavirus infection, Germany

scientific article published in December 2011

Severe pneumonia and human bocavirus in adult

scientific article

Shift of HIV tropism in stem-cell transplantation with CCR5 Delta32 mutation

scientific article published in August 2014

Short communication: selection of thymidine analogue resistance mutational patterns in children infected from a common HIV type 1 subtype G source

scientific article published in March 2010

Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART

scientific article published on 26 September 2006

Standardized representation, visualization and searchable repository of antiretroviral treatment-change episodes

scientific article (publication date: 3 May 2012)

State of the Art in HIV Drug Resistance: Science and Technology Knowledge Gap

State of the Art in HIV Drug Resistance: Surveillance and Regional Gaps

article

Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment

scientific article published in November 2004

Tenofovir resistance and resensitization

scientific article published on November 2003

The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage?

scientific article

The SnoB study: frequency of baseline raltegravir resistance mutations prevalence in different non-B subtypes ⬇️

scientific article published on April 8, 2011

The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V.

scientific article published in March 2010

Time on drug analysis based on real life data

scientific article

Trends of Transmitted and Acquired Drug Resistance in Europe From 1981 to 2019: A Comparison Between the Populations of Late Presenters and Non-late Presenters

scientific article published on 13 April 2022

Trends of prevalence of primary HIV drug resistance in Germany

scientific article published on 22 August 2007

Two Distinct Hepatitis C Virus Genotype 1a Clades Have Different Geographical Distribution and Association With Natural Resistance to NS3 Protease Inhibitors

scientific article published on 31 March 2015

Using drug exposure for predicting drug resistance - A data-driven genotypic interpretation tool

scientific article (publication date: 2017)

V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV.

scientific article

[Resistance screening]

scientific article published on 01 April 2009

geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data.

scientific article published in May 2018

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