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List of works by Arthur Krieg

A CpG oligonucleotide can protect mice from a low aerosol challenge dose of Burkholderia mallei

scientific article

A combination of Flt3 ligand cDNA and CpG ODN as nasal adjuvant elicits NALT dendritic cells for prolonged mucosal immunity

scientific article published on 14 July 2008

A possible cause of joint destruction in septic arthritis

scientific article

Activation of innate immunity in healthy Macaca mulatta macaques by a single subcutaneous dose of GMP CpG 7909: safety data and interferon-inducible protein-10 kinetics for humans and macaques

scientific article

Antiinfective applications of toll-like receptor 9 agonists

scientific article published on July 2007

Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides

scientific article published on March 2004

Biodistribution and metabolism of immunostimulatory oligodeoxynucleotide CPG 7909 in mouse and rat tissues following subcutaneous administration

scientific article

Cancer and inflammation: promise for biologic therapy.

scientific article

Clinical evaluation of safety and immunogenicity of PADRE-cytomegalovirus (CMV) and tetanus-CMV fusion peptide vaccines with or without PF03512676 adjuvant

scientific article published on 7 March 2012

Combining vaccination and postexposure CpG therapy provides optimal protection against lethal sepsis in a biodefense model of human melioidosis

scientific article

CpG DNA: Trigger of Sepsis, Mediator of Protection, or Both?

scientific article published on January 1, 2003

CpG Still Rocks! Update on an Accidental Drug

scientific article published on February 21, 2012

CpG motifs in bacterial DNA and their immune effects

scientific article

CpG motifs: the active ingredient in bacterial extracts?

scientific article

CpG oligodeoxynucleotide and Montanide ISA 51 adjuvant combination enhanced the protective efficacy of a subunit malaria vaccine

scientific article published on February 2004

CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection

scientific article

Dendritic cells from HIV-1 infected individuals are less responsive to toll-like receptor (TLR) ligands.

scientific article

Deoxycytidyl-deoxyguanosine oligonucleotide classes A, B, and C induce distinct cytokine gene expression patterns in rhesus monkey peripheral blood mononuclear cells and distinct alpha interferon responses in TLR9-expressing rhesus monkey plasmacyto

scientific article

Development of TLR9 agonists for cancer therapy

scientific article published on May 2007

Early development of the Toll-like receptor 9 agonist, PF-3512676, for the treatment of patients with advanced cancers

scientific article published on May 1, 2009

Enhanced antibody responses elicited by a CpG adjuvant do not improve the protective effect of an aldrithiol-2-inactivated simian immunodeficiency virus therapeutic AIDS vaccine

scientific article published on 18 February 2009

Enhancing antisense efficacy with multimers and multi-targeting oligonucleotides (MTOs) using cleavable linkers

scientific article

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

scientific article

Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8.

scientific article

Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8+ T cells in melanoma patients

scientific article published on October 2008

Immunostimulatory CpG oligodeoxynucleotide confers protection in a murine model of infection with Burkholderia pseudomallei.

scientific article

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

scientific article

Induction of CD8 T-cell-specific systemic and mucosal immunity against herpes simplex virus with CpG-peptide complexes

scientific article

Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery

scientific article published on March 15, 2012

Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma

scientific article

Oral pretreatment of mice with CpG DNA reduces susceptibility to oral or intraperitoneal challenge with virulent Listeria monocytogenes

scientific article

PD-1 and Tim-3 regulate the expansion of tumor antigen-specific CD8⁺ T cells induced by melanoma vaccines

scientific article published on 16 December 2013

Positive T cell co-stimulation by TLR7/8 ligands is dependent on the cellular environment

scientific article

Randomized phase II trial of a toll-like receptor 9 agonist oligodeoxynucleotide, PF-3512676, in combination with first-line taxane plus platinum chemotherapy for advanced-stage non-small-cell lung cancer

scientific article

Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.

scientific article published in March 2005

Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses

scientific article

Stimulation via Toll-like receptor 9 reduces Cryptococcus neoformans-induced pulmonary inflammation in an IL-12-dependent manner

scientific article

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

scientific article published on 09 July 2008

Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy

scientific article

The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques

scientific article

The toll of too much TLR7.

scientific article

Therapeutic potential of Toll-like receptor 9 activation

scientific article published on June 2006

Toll-like receptor 9 activation with CpG oligodeoxynucleotides for asthma therapy

scientific article published on October 2008

Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila

scientific article published on 21 April 2008

Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity

scientific article published on December 2007