List of works - Christine Trumpfheller

Abstract 2853: Co-delivery of antigen-encoding mRNA and signal 2/3 mRNAs to PBMCs by Cell Squeeze® technology generates SQZ™ eAPCs that prime CD8+T cells in a humanized mouse model

scientific article published in 2022

Cell type-dependent retention and transmission of HIV-1 by DC-SIGN.

scientific article published on February 2003

Combinations of Toll-like receptor 8 agonist TL8-506 activate human tumor-derived dendritic cells

scientific article published on 01 June 2022

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

scientific article

DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells

scientific article

DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes

scientific article

DEC-205/CD205+ dendritic cells are abundant in the white pulp of the human spleen, including the border region between the red and white pulp

scientific article published on 16 October 2007

Dendritic Cells in Tolerance and Immunity against Pathogens

scientific article published on 31 March 2016

Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8+ T cells

scientific article

Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin/CD209 is abundant on macrophages in the normal human lymph node and is not required for dendritic cell stimulation of the mixed leukocyte reaction

scientific article

Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant

scientific article published on 29 June 2009

Differential antigen processing by dendritic cell subsets in vivo

scientific article (publication date: 5 January 2007)

HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine DC.

scientific article published on January 2010

HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood

scientific article published on 01 January 2006

HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation

scholarly article

Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves

scientific article published on 16 February 2009

Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates.

scientific article

Immunogenicity of DNA vaccines encoding simian immunodeficiency virus antigen targeted to dendritic cells in rhesus macaques

scientific article (publication date: 2012)

Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti–human DEC205 monoclonal antibody ⬇️

scientific article published on July 28, 2010

Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine

scientific article

Quantitative histology by multicolor slide-based cytometry

scientific article

Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein.

scientific article

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

scientific article published on 7 November 2011

Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques

scientific article

Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses.

scientific article published on 2 June 2008

The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

scientific article

The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine

scholarly article

List of works by Christine Trumpfheller

Abstract 2853: Co-delivery of antigen-encoding mRNA and signal 2/3 mRNAs to PBMCs by Cell Squeeze® technology generates SQZ™ eAPCs that prime CD8+T cells in a humanized mouse model

Cell type-dependent retention and transmission of HIV-1 by DC-SIGN.

Combinations of Toll-like receptor 8 agonist TL8-506 activate human tumor-derived dendritic cells

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells

DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes

DEC-205/CD205+ dendritic cells are abundant in the white pulp of the human spleen, including the border region between the red and white pulp

Dendritic Cells in Tolerance and Immunity against Pathogens

Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8+ T cells

Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin/CD209 is abundant on macrophages in the normal human lymph node and is not required for dendritic cell stimulation of the mixed leukocyte reaction

Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant

Differential antigen processing by dendritic cell subsets in vivo

HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine DC.

HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood

HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation

Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves

Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates.

Immunogenicity of DNA vaccines encoding simian immunodeficiency virus antigen targeted to dendritic cells in rhesus macaques

Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti–human DEC205 monoclonal antibody ⬇️

Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine

Quantitative histology by multicolor slide-based cytometry

Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein.

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques

Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses.

The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine