List of works - Philip Crosier

13-P017 Live imaging demand-driven myelopoiesis ⬇️

scientific article published in August 2009

A COL17A1 Splice-Altering Mutation Is Prevalent in Inherited Recurrent Corneal Erosions

scientific article published on 16 January 2016

A Zebrafish Model for Chlamydia Infection with the Obligate Intracellular Pathogen Waddlia chondrophila

scientific article

A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents

scientific article published on 01 January 2011

A hierarchy of Runx transcription factors modulate the onset of chondrogenesis in craniofacial endochondral bones in zebrafish.

scientific article published in November 2006

A high-throughput lab-on-a-chip interface for zebrafish embryo tests in drug discovery and ecotoxicology ⬇️

scientific article published on 7 December 2013

A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation

scientific article

A zebrafish model of inflammatory lymphangiogenesis

scientific article

An essential role for zebrafish Fgfrl1 during gill cartilage development

scientific article published on 24 August 2006

An in vivo antilymphatic screen in zebrafish identifies novel inhibitors of mammalian lymphangiogenesis and lymphatic-mediated metastasis.

scientific article published on 22 July 2014

An inducible transgene reports activation of macrophages in live zebrafish larvae.

scientific article

Analysis of WASp function during the wound inflammatory response--live-imaging studies in zebrafish larvae

scientific article

Arap3 is dysregulated in a mouse model of hypotrichosis-lymphedema-telangiectasia and regulates lymphatic vascular development.

scientific article

Assessment of biocompatibility of 3D printed photopolymers using zebrafish embryo toxicity assays.

scientific article published on 08 December 2015

Blocking fatty acid-fueled mROS production within macrophages alleviates acute gouty inflammation.

scientific article published on 26 March 2018

Cadherin-17 is required to maintain pronephric duct integrity during zebrafish development.

scientific article

Chemically induced intestinal damage models in zebrafish larvae.

scientific article published on 28 February 2013

Cohesin-dependent regulation of Runx genes

scientific article published on 13 June 2007

DMXAA (Vadimezan, ASA404) is a multi-kinase inhibitor targeting VEGFR2 in particular.

scientific article published in May 2012

Dual oxidase in the intestinal epithelium of zebrafish larvae has anti-bacterial properties

scientific article published on 13 August 2010

Duplicate zebrafish runx2 orthologues are expressed in developing skeletal elements

scientific article published in September 2004

Dynamic analysis of angiogenesis in transgenic zebrafish embryos using a 3D multilayer chip-based technology

Editorial: Maintaining the balance--fishing for drugs to treat persistent neutrophilic inflammation

scientific article published in February 2010

Epidermal cells help coordinate leukocyte migration during inflammation through fatty acid-fuelled matrix metalloproteinase production

scientific article published on 23 May 2014

Expression and functional analysis of two isoforms of the human GM‐CSF receptor α chain in myeloid development and leukaemia ⬇️

scientific article published on September 1, 1997

Expression of isoforms of the human receptor tyrosine kinase c-kit in leukemic cell lines and acute myeloid leukemia ⬇️

scientific article published on August 15, 1993

Expression of zebrafish cxcl8 (interleukin-8) and its receptors during development and in response to immune stimulation.

scientific article published in December 2009

Fish on Chips: Automated Microfluidic Living Embryo Arrays ⬇️

scientific article published in 2012

Fish on chips: Microfluidic living embryo array for accelerated in vivo angiogenesis assays ⬇️

scientific article published in December 2013

Fishing on chips: up-and-coming technological advances in analysis of zebrafish and Xenopus embryos

scientific article published on 06 October 2014

Immobilization of zebrafish larvae on a chip-based device for environmental scanning electron microscopy (ESEM) imaging ⬇️

scientific article published on 7 December 2013

Immunoresponsive gene 1 augments bactericidal activity of macrophage-lineage cells by regulating β-oxidation-dependent mitochondrial ROS production

scientific article published on August 2013

In situ hybridization screen in zebrafish for the selection of genes encoding secreted proteins.

scientific article

Induction of tumor necrosis factor-alpha messenger RNA in human and murine cells by the flavone acetic acid analogue 5,6-dimethylxanthenone-4-acetic acid (NSC 640488).

scientific article published on February 1994

Infection-responsive expansion of the hematopoietic stem and progenitor cell compartment in zebrafish is dependent upon inducible nitric oxide.

scientific article published in February 2012

Inflammatory cytokines provide both infection-responsive and developmental signals for blood development: Lessons from the zebrafish

scientific article

Inflammatory pathway network-based drug repositioning and molecular phenomics

scientific article published on 27 June 2016

Innate immune cells and bacterial infection in zebrafish.

scientific article published on 8 October 2016

Integrated chip-based physiometer for automated fish embryo toxicity biotests in pharmaceutical screening and ecotoxicology.

scientific article

Interception of host angiogenic signalling limits mycobacterial growth.

scientific article

Interfacing Lab-on-a-Chip Embryo Technology with High-Definition Imaging Cytometry.

scientific article published on July 2015

Intestinal differentiation in zebrafish requires Cdx1b, a functional equivalent of mammalian Cdx2.

scientific article

Isolation and characterization of the human DTK receptor tyrosine kinase

scientific article

Liposome-Mediated Drug Delivery in Larval Zebrafish to Manipulate Macrophage Function

scientific article published on 06 February 2019

Live cell imaging of zebrafish leukocytes

scientific article

Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells.

scientific article published on 7 May 2010

Lymphatics, Cancer and Zebrafish.

scientific article published on January 2016

Macrophages enhance Vegfa-driven angiogenesis in an embryonic zebrafish tumour xenograft model

scientific article published on 29 November 2018

Microfluidic device for a rapid immobilization of zebrafish larvae in environmental scanning electron microscopy

scientific article published on 5 December 2014

Miniaturized embryo array for automated trapping, immobilization and microperfusion of zebrafish embryos

scientific article (publication date: 2012)

Mitochondrial metabolism, reactive oxygen species, and macrophage function-fishing for insights

scientific article

Molecular cloning and characterization of murine interleukin-11

scientific article

Neutrophil-delivered myeloperoxidase dampens the hydrogen peroxide burst after tissue wounding in zebrafish.

scientific article published on 30 August 2012

Neutrophils exert protection in the early tuberculous granuloma by oxidative killing of mycobacteria phagocytosed from infected macrophages

scientific article published on September 2012

New insights into the control of cell growth; the role of the AxI family

scientific article published on May 1997

New rationale for large metazoan embryo manipulations on chip-based devices

scientific article

OpenSource lab-on-a-chip physiometer for accelerated zebrafish embryo biotests

scientific article

Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis

scientific article published on 4 June 2015

Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish.

scientific article published on 3 February 2008

Pathways in blood and vessel development revealed through zebrafish genetics.

scientific article

Pkd1 regulates lymphatic vascular morphogenesis during development

scientific journal article

Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved

scientific article

Pseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryos

scientific article

Radar is required for the establishment of vascular integrity in the zebrafish

scientific article published in November 2002

Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling

scientific article published on 25 July 2013

Repositioning drugs for inflammatory disease - fishing for new anti-inflammatory agents

scientific article

Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis

scientific article

Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.

scientific article

Runx3 is required for hematopoietic development in zebrafish

scientific article

S16-03 Live imaging reveals that definitive haematopoietic stem cells emerge directly from haemogenic endothelial cells in zebrafish embryos ⬇️

scientific article published in August 2009

Screening of anti-mycobacterial compounds in a naturally infected zebrafish larvae model

scientific article

The inflammatory bowel disease (IBD) susceptibility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish

scientific article published on 4 July 2011

The innate immune cell response to bacterial infection in larval zebrafish is light-regulated

scientific article published on 4 October 2017

The zebrafish lysozyme C promoter drives myeloid-specific expression in transgenic fish

scientific article

The zebrafish retinoid-related orphan receptor (ror) gene family.

scientific article published on 13 February 2007

Through the looking-glass: observing HSCs through the lens of infection reveals unexpected insights into HSC function

scientific article published on 8 August 2012

Topographical distribution of antimicrobial genes in the zebrafish intestine.

scientific article

Toward embedded laboratory automation for smart Lab-on-a-Chip embryo arrays.

scientific article published on 30 April 2013

Transgenic zebrafish reporter lines reveal conserved Toll-like receptor signaling potential in embryonic myeloid leukocytes and adult immune cell lineages

scientific article

Transient inflammatory response mediated by interleukin-1β is required for proper regeneration in zebrafish fin fold

scientific article published on 23 February 2017

Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish

scientific article

Vegfd can compensate for loss of Vegfc in zebrafish facial lymphatic sprouting

scientific article published on 05 June 2014

Visualization of embryonic lymphangiogenesis advances the use of the zebrafish model for research in cancer and lymphatic pathologies

scientific article published in July 2010

Zebrafish facial lymphatics develop through sequential addition of venous and non-venous progenitors

scientific article published on 15 March 2019

Zebrafish heat shock protein a4 genes in the intestinal epithelium are up-regulated during inflammation

scientific article published on 13 October 2011

Zebrafish runx1 promoter-EGFP transgenics mark discrete sites of definitive blood progenitors.

scientific article

lyve1 expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafish.

scientific article

mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish

scientific article

List of works by Philip Crosier

13-P017 Live imaging demand-driven myelopoiesis ⬇️

A COL17A1 Splice-Altering Mutation Is Prevalent in Inherited Recurrent Corneal Erosions

A Zebrafish Model for Chlamydia Infection with the Obligate Intracellular Pathogen Waddlia chondrophila

A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents

A hierarchy of Runx transcription factors modulate the onset of chondrogenesis in craniofacial endochondral bones in zebrafish.

A high-throughput lab-on-a-chip interface for zebrafish embryo tests in drug discovery and ecotoxicology ⬇️

A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation

A zebrafish model of inflammatory lymphangiogenesis

An essential role for zebrafish Fgfrl1 during gill cartilage development

An in vivo antilymphatic screen in zebrafish identifies novel inhibitors of mammalian lymphangiogenesis and lymphatic-mediated metastasis.

An inducible transgene reports activation of macrophages in live zebrafish larvae.

Analysis of WASp function during the wound inflammatory response--live-imaging studies in zebrafish larvae

Arap3 is dysregulated in a mouse model of hypotrichosis-lymphedema-telangiectasia and regulates lymphatic vascular development.

Assessment of biocompatibility of 3D printed photopolymers using zebrafish embryo toxicity assays.

Blocking fatty acid-fueled mROS production within macrophages alleviates acute gouty inflammation.

Cadherin-17 is required to maintain pronephric duct integrity during zebrafish development.

Chemically induced intestinal damage models in zebrafish larvae.

Cohesin-dependent regulation of Runx genes

DMXAA (Vadimezan, ASA404) is a multi-kinase inhibitor targeting VEGFR2 in particular.

Dual oxidase in the intestinal epithelium of zebrafish larvae has anti-bacterial properties

Duplicate zebrafish runx2 orthologues are expressed in developing skeletal elements

Dynamic analysis of angiogenesis in transgenic zebrafish embryos using a 3D multilayer chip-based technology

Editorial: Maintaining the balance--fishing for drugs to treat persistent neutrophilic inflammation

Epidermal cells help coordinate leukocyte migration during inflammation through fatty acid-fuelled matrix metalloproteinase production

Expression and functional analysis of two isoforms of the human GM‐CSF receptor α chain in myeloid development and leukaemia ⬇️

Expression of isoforms of the human receptor tyrosine kinase c-kit in leukemic cell lines and acute myeloid leukemia ⬇️

Expression of zebrafish cxcl8 (interleukin-8) and its receptors during development and in response to immune stimulation.

Fish on Chips: Automated Microfluidic Living Embryo Arrays ⬇️

Fish on chips: Microfluidic living embryo array for accelerated in vivo angiogenesis assays ⬇️

Fishing on chips: up-and-coming technological advances in analysis of zebrafish and Xenopus embryos

Immobilization of zebrafish larvae on a chip-based device for environmental scanning electron microscopy (ESEM) imaging ⬇️

Immunoresponsive gene 1 augments bactericidal activity of macrophage-lineage cells by regulating β-oxidation-dependent mitochondrial ROS production

In situ hybridization screen in zebrafish for the selection of genes encoding secreted proteins.

Induction of tumor necrosis factor-alpha messenger RNA in human and murine cells by the flavone acetic acid analogue 5,6-dimethylxanthenone-4-acetic acid (NSC 640488).

Infection-responsive expansion of the hematopoietic stem and progenitor cell compartment in zebrafish is dependent upon inducible nitric oxide.

Inflammatory cytokines provide both infection-responsive and developmental signals for blood development: Lessons from the zebrafish

Inflammatory pathway network-based drug repositioning and molecular phenomics

Innate immune cells and bacterial infection in zebrafish.

Integrated chip-based physiometer for automated fish embryo toxicity biotests in pharmaceutical screening and ecotoxicology.

Interception of host angiogenic signalling limits mycobacterial growth.

Interfacing Lab-on-a-Chip Embryo Technology with High-Definition Imaging Cytometry.

Intestinal differentiation in zebrafish requires Cdx1b, a functional equivalent of mammalian Cdx2.

Isolation and characterization of the human DTK receptor tyrosine kinase

Liposome-Mediated Drug Delivery in Larval Zebrafish to Manipulate Macrophage Function

Live cell imaging of zebrafish leukocytes

Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells.

Lymphatics, Cancer and Zebrafish.

Macrophages enhance Vegfa-driven angiogenesis in an embryonic zebrafish tumour xenograft model

Microfluidic device for a rapid immobilization of zebrafish larvae in environmental scanning electron microscopy

Miniaturized embryo array for automated trapping, immobilization and microperfusion of zebrafish embryos

Mitochondrial metabolism, reactive oxygen species, and macrophage function-fishing for insights

Molecular cloning and characterization of murine interleukin-11

Neutrophil-delivered myeloperoxidase dampens the hydrogen peroxide burst after tissue wounding in zebrafish.

Neutrophils exert protection in the early tuberculous granuloma by oxidative killing of mycobacteria phagocytosed from infected macrophages

New insights into the control of cell growth; the role of the AxI family

New rationale for large metazoan embryo manipulations on chip-based devices

OpenSource lab-on-a-chip physiometer for accelerated zebrafish embryo biotests

Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis

Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish.

Pathways in blood and vessel development revealed through zebrafish genetics.

Pkd1 regulates lymphatic vascular morphogenesis during development

Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved

Pseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryos

Radar is required for the establishment of vascular integrity in the zebrafish

Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling

Repositioning drugs for inflammatory disease - fishing for new anti-inflammatory agents

Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis

Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.

Runx3 is required for hematopoietic development in zebrafish

S16-03 Live imaging reveals that definitive haematopoietic stem cells emerge directly from haemogenic endothelial cells in zebrafish embryos ⬇️

Screening of anti-mycobacterial compounds in a naturally infected zebrafish larvae model

The inflammatory bowel disease (IBD) susceptibility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish

The innate immune cell response to bacterial infection in larval zebrafish is light-regulated

The zebrafish lysozyme C promoter drives myeloid-specific expression in transgenic fish

The zebrafish retinoid-related orphan receptor (ror) gene family.

Through the looking-glass: observing HSCs through the lens of infection reveals unexpected insights into HSC function

Topographical distribution of antimicrobial genes in the zebrafish intestine.

Toward embedded laboratory automation for smart Lab-on-a-Chip embryo arrays.

Transgenic zebrafish reporter lines reveal conserved Toll-like receptor signaling potential in embryonic myeloid leukocytes and adult immune cell lineages