List of works - Marie K Mankowski

A novel anti-HIV active integrase inhibitor with a favorable in vitro cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase metabolism profile.

scientific article

Abasic phosphorothioate oligomers inhibit HIV-1 reverse transcription and block virus transmission across polarized ectocervical organ cultures.

scientific article

Albumin-conjugated C34 peptide HIV-1 fusion inhibitor: equipotent to C34 and T-20 in vitro with sustained activity in SCID-hu Thy/Liv mice

scientific article published on 22 September 2008

An analog of camptothecin inactive against Topoisomerase I is broadly neutralizing of HIV-1 through inhibition of Vif-dependent APOBEC3G degradation.

scientific article published on 4 November 2016

Critical design features of phenyl carboxylate-containing polymer microbicides

scientific article

Cross-reactive HIV-1-neutralizing activity of serum IgG from a rabbit immunized with gp41 fused to IgG1 Fc: possible role of the prolonged half-life of the immunogen

scientific article

Development of a comprehensive human immunodeficiency virus type 1 screening algorithm for discovery and preclinical testing of topical microbicides.

scientific article published on 3 March 2008

Development of hexadecyloxypropyl tenofovir (CMX157) for treatment of infection caused by wild-type and nucleoside/nucleotide-resistant HIV.

scientific article

Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacement

scientific article published on December 2014

Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein.

scientific article published on 29 November 2012

Evaluation of PD 404,182 as an anti-HIV and anti-herpes simplex virus microbicide

scientific article

Exploring Modifications of an HIV-1 Capsid Inhibitor: Design, Synthesis, and Mechanism of Action

article

Highly Potent Chimeric Inhibitors Targeting Two Steps of HIV Cell Entry ⬇️

scientific article published on June 9, 2011

Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein

scientific article

Identification of a small-molecule inhibitor of HIV-1 assembly that targets the phosphatidylinositol (4,5)-bisphosphate binding site of the HIV-1 matrix protein.

scientific article

In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories

scientific article

Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid

scientific article published on 30 May 2012

Inhibition of HIV-1 Replication by Amphotericin B Methyl Ester

scientific article published in Journal of Biological Chemistry

Potent Strategy To Inhibit HIV-1 by Binding both gp120 and gp41 ⬇️

scientific article published on October 18, 2010

Redoxal, an inhibitor of de novo pyrimidine biosynthesis, augments APOBEC3G antiviral activity against human immunodeficiency virus type 1. ⬇️

scientific article published on 30 June 2015

Safety and anti-HIV assessments of natural vaginal cleansing products in an established topical microbicides in vitro testing algorithm

scientific article

Structure-activity relationship studies of indole-based compounds as small molecule HIV-1 fusion inhibitors targeting glycoprotein 41.

scientific article

Structure-activity relationships of a novel capsid targeted inhibitor of HIV-1 replication

scientific article published on 28 October 2014

List of works by Marie K Mankowski

A novel anti-HIV active integrase inhibitor with a favorable in vitro cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase metabolism profile.

Abasic phosphorothioate oligomers inhibit HIV-1 reverse transcription and block virus transmission across polarized ectocervical organ cultures.

Albumin-conjugated C34 peptide HIV-1 fusion inhibitor: equipotent to C34 and T-20 in vitro with sustained activity in SCID-hu Thy/Liv mice

An analog of camptothecin inactive against Topoisomerase I is broadly neutralizing of HIV-1 through inhibition of Vif-dependent APOBEC3G degradation.

Critical design features of phenyl carboxylate-containing polymer microbicides

Cross-reactive HIV-1-neutralizing activity of serum IgG from a rabbit immunized with gp41 fused to IgG1 Fc: possible role of the prolonged half-life of the immunogen

Development of a comprehensive human immunodeficiency virus type 1 screening algorithm for discovery and preclinical testing of topical microbicides.

Development of hexadecyloxypropyl tenofovir (CMX157) for treatment of infection caused by wild-type and nucleoside/nucleotide-resistant HIV.

Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacement

Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein.

Evaluation of PD 404,182 as an anti-HIV and anti-herpes simplex virus microbicide

Exploring Modifications of an HIV-1 Capsid Inhibitor: Design, Synthesis, and Mechanism of Action

Highly Potent Chimeric Inhibitors Targeting Two Steps of HIV Cell Entry ⬇️

Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein

Identification of a small-molecule inhibitor of HIV-1 assembly that targets the phosphatidylinositol (4,5)-bisphosphate binding site of the HIV-1 matrix protein.

In vitro preclinical testing of nonoxynol-9 as potential anti-human immunodeficiency virus microbicide: a retrospective analysis of results from five laboratories

Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid

Inhibition of HIV-1 Replication by Amphotericin B Methyl Ester

Potent Strategy To Inhibit HIV-1 by Binding both gp120 and gp41 ⬇️

Redoxal, an inhibitor of de novo pyrimidine biosynthesis, augments APOBEC3G antiviral activity against human immunodeficiency virus type 1. ⬇️

Safety and anti-HIV assessments of natural vaginal cleansing products in an established topical microbicides in vitro testing algorithm

Structure-activity relationship studies of indole-based compounds as small molecule HIV-1 fusion inhibitors targeting glycoprotein 41.

Structure-activity relationships of a novel capsid targeted inhibitor of HIV-1 replication