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List of works by Vasu Nair

A heterocyclic molecule with significant activity against dengue virus

scientific article

A new approach for the synthesis of novel 5-substituted isodeoxyuridine analogs

scientific article published in January 2004

A non-natural dinucleotide containing an isomeric L-related deoxynucleoside: dinucleotide inhibitors of anti-HIV integrase activity

scientific article

A novel anti-HIV active integrase inhibitor with a favorable in vitro cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase metabolism profile.

scientific article

A novel diketo phosphonic acid that exhibits specific, strand-transfer inhibition of HIV integrase and anti-HIV activity

scientific article published on 15 December 2006

A novel molecule with notable activity against multi-drug resistant tuberculosis

scientific article

A novel strategy to assemble the beta-diketo acid pharmacophore of HIV integrase inhibitors on purine nucleobase scaffolds

scientific article published on 5 October 2007

A thymidine phosphorylase-stable analogue of BVDU with significant antiviral activity

scientific article published on December 2002

Acyclic nucleosides bearing a furanyl scaffold

scientific article published in January 2005

Approaches to the synthesis of a novel, anti-HIV active integrase inhibitor

scientific article published on 07 October 2013

Azadideoxyadenosine: synthesis, enzymology, and anti-HIV activity

scientific article published on 12 May 2006

Base-functionalized carbocyclic nucleosides: design, synthesis, and mechanism of antiviral activity

scientific article

Beta-diketo acids with purine nucleobase scaffolds: novel, selective inhibitors of the strand transfer step of HIV integrase

scientific article published on 24 January 2006

Binding modes of two novel dinucleotide inhibitors of HIV-1 integrase

scientific article

Biologically-validated HIV integrase inhibitors with nucleobase scaffolds: structure, synthesis, chemical biology, molecular modeling, and antiviral activity

scientific article published in January 2007

Cyclopropyl and related analogs of the anti-HIV compound, isodideoxyadenosine

scientific article

Design and synthesis of specific inhibitors of the 3'-processing step of HIV-1 integrase

scientific article

Discovery of a Potent HIV Integrase Inhibitor That Leads to a Prodrug with Significant anti-HIV Activity ⬇️

scientific article published on October 5, 2011

HIV integrase as a target for antiviral chemotherapy

scientific article

HIV integrase inhibitors as therapeutic agents in AIDS.

scientific article published on July 2007

HIV integrase inhibitors with nucleobase scaffolds: discovery of a highly potent anti-HIV agent

scientific article published on January 2006

IMPDH as a biological probe for RNA antiviral drug discovery: synthesis, enzymology, molecular docking, and antiviral activity of new ribonucleosides with surrogate bases

scientific article published in January 2007

Inhibition of inosine monophosphate dehydrogenase (IMPDH) by 2-[2-(Z)-fluorovinyl]inosine 5'-monophosphate

scientific article published in February 2003

Inhibition of inosine monophosphate dehydrogenase (IMPDH) by the antiviral compound, 2-vinylinosine monophosphate

scientific article

Inhibition of the strand transfer step of HIV-1 integrase by non-natural dinucleotides

scientific article published in October 2004

Inosine monophosphate dehydrogenase (IMPDH) as a target in drug discovery

scientific article published on March 2008

Inosine monophosphate dehydrogenase as a probe in antiviral drug discovery

scientific article published on January 2007

Integrase Inhibitor Prodrugs: Approaches to Enhancing the Anti-HIV Activity of β-Diketo Acids

scientific article (publication date: 2015)

Isonucleosides: design and synthesis of new isomeric nucleosides with antiviral potential

scientific article published in January 2007

NEW BASE-ALTERED ADENOSINE ANALOGUES: SYNTHESIS AND AFFINITY AT ADENOSINE A1 and A2A RECEPTORS.

scientific article

Notable difference in anti-HIV activity of integrase inhibitors as a consequence of geometric and enantiomeric configurations.

scientific article published on 23 May 2013

Novel Inhibitors of HIV Integrase: The Discovery of Potential Anti-HIV Therapeutic Agents ⬇️

scientific article published on January 1, 2003

Pharmacokinetics and dose-range finding toxicity of a novel anti-HIV active integrase inhibitor

scientific article

Resistance towards exonucleases of dinucleotides with stereochemically altered internucleotide phosphate bonds

scientific article published in January 2004

Ribonucleosides bearing Michael acceptors: synthesis, molecular docking, enzyme inhibition data and antiviral activity

scientific article

Solid-state tautomeric structure and invariom refinement of a novel and potent HIV integrase inhibitor ⬇️

scientific article published on February 14, 2013

Synthesis and biological activities of 2-functionalized purine nucleosides

scientific article published in February 2003

Synthesis of a novel carbocyclic analog of bredinin

scientific article published on 17 September 2013

Synthetic approaches to nuclease-resistant, nonnatural dinucleotides of anti-HIV integrase interest

scientific article published in January 2005

The antiviral activity, mechanism of action, clinical significance and resistance of abacavir in the treatment of pediatric AIDS.

scientific article

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